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UrduA new study from Washington University School of Medicine in St. Louis indicates that people with dementia – whose parents also had dementia – develop symptoms an average of six years earlier than their parents.
Tag: Alzheimer’s Disease
Novel agent flips on garbage disposal in neurons, eliminating toxic brain proteins in mice
CHICAGO — Neuroscientists at Georgetown University Medical Center say they have developed and tested an agent that reduces the buildup of toxic proteins in animal models of both Parkinson’s and Alzheimer’s diseases, and improves cognitive and motor behavior. The team…
In Alzheimer’s research, MIT scientists reveal brain rhythm role
In the years since her lab discovered that exposing Alzheimer’s disease model mice to light flickering at the frequency of a key brain rhythm could stem the disorder’s pathology, MIT neuroscientist Li-Huei Tsai and her team at The Picower Institute…
Biogen to submit aducanumab results in early Alzheimer’s to US FDA
Alzheimer’s Association statement
Twin study shows what’s good for the heart is good for the brain
Relationship between CV risk and cognitive decline
Cantabio Pharmaceuticals and LIH collaborate on the therapeutic targeting of DJ-1
The collaboration aims to explore the use of Cantabio’s DJ-1 protein targeting small molecule drug candidates in immune associated diseases at Luxembourg Institute of Health (LIH)
Salk scientists receive $12.9 million from NIH BRAIN Initiative
LA JOLLA–(October 21, 2019) Salk Institute scientists Nicola Allen, Eiman Azim, Margarita Behrens, and Joseph Ecker have been named recipients in the 2019 round of grants from the National Institutes of Health (NIH) to better understand the brain. The grants,…
Metabolic disturbance in the brain exacerbates, may forewarn Alzheimer’s pathology
New research uncovers the interplay between metabolic process and other signs of the disease
Dementia and eating disorders: it is a problem of (semantic) memory
New research sheds light on the possible origin of eating disorders in patients suffering from dementia
NIH continues support of Kent State Alzheimer’s researcher with new two-year grant
Once it begins, Alzheimer’s disease progresses systematically and aggressively, attacking victims on multiple fronts. But scientists studying the disease operate the same way – like Kent State University’s own Gemma Casadesus Smith, Ph.D. Since 2016, Casadesus Smith, professor of biological…
Could young blood hold secrets to longer, healthier life?
In what sounds like a scene from a science fiction movie, researchers in 2005 stitched together old and young mice so they shared a circulatory system. Youthful blood seemingly rejuvenated many tissues of the elderly rodents, boosting their cognitive and…
Researchers Develop mouse model of human gene involved in Alzheimer’s disease
Findings reported at ASHG 2019 Annual Meeting
In a first, scientists pinpoint neural activity’s role in human longevity
The brain’s neural activity–long implicated in disorders ranging from dementia to epilepsy–also plays a role in human aging and life span, according to research led by scientists in the Blavatnik Institute at Harvard Medical School. The study, published Oct. 16…
NIH scientists develop test for uncommon brain diseases
Samples of cerebrospinal fluid used to detect tauopathies
First study to test healthy lifestyle changes in reducing the risk of dementia in a large-scale, diverse population in the United States
A new study at Rush University Medical Center aims to determine whether a combination of lifestyle changes can protect memory and thinking skills in people at risk of developing dementia. The two-year U.S. Study to Protect Brain Health Through Lifestyle…
Protein misfolding as a risk marker for Alzheimer’s disease
Detection up to 14 years before the diagnosis
The New York Stem Cell Foundation Annual Conference
The New York Stem Cell Foundation’s (NYSCF) 14th Annual Conference convenes global leaders in stem cell research to present their latest progress towards new treatments and cures for the most devastating diseases and injuries in the world.
Overcoming the blood-brain-barrier: Delivering therapeutics to the brain
For the first time, scientists have identified a simple way that can effectively transport medication into the brain – which could lead to improved treatments for neurological and neurodegenerative diseases. In a study published today in Nature Communications , scientists…
Illumination of abnormal neuronal activities caused by myelin impairment
Suggests possible contribution to learning deficits
Dial In to the Cutting-edge Neuroscience at ANA2019 during the October 15 Media Roundtable
In a media roundtable at 11 a.m. U.S. Central on Tuesday, October 15, leading neuroscientists will summarize key science being presented at the American Neurological Association’s 2019 Annual Meeting (ANA2019). Reporters may attend in person or dial in.
New Diagnostic Criteria May Enable Earlier Detection of Cognitive Impairment in Women
Study finds when verbal memory test cut-offs were tailored to patient sex, more female patients and fewer male patients were considered to have amnesic mild cognitive impairment. This could change the way aMCI diagnoses are determined and make it easier to catch the condition in its early stages.
Using plasma to find Alzheimer’s
National Institute on Aging awards $225,000 for work to improve Alzheimer’s diagnoses
Tau-mediated RNA splicing errors linked to Alzheimer’s disease
A collaborative study published today in the journal Cell Reports provides evidence for a new molecular cause for neurodegeneration in Alzheimer’s disease. The study, led by researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research…
$2.8 Million Grant Will Fund Preclinical Study of New Dementia Treatment
LEXINGTON, Ky. (Oct. 7, 2019) — The Sanders-Brown Center on Aging has received a five-year, $2.8 million grant to underwrite preclinical efficacy studies of a potential new treatment for dementia. The drug candidate, called MW150, targets dysregulated brain inflammation driven…
An oral anticoagulant delays the appearance of Alzheimer’s disease in mice
Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have identified a possible treatment for Alzheimer disease. Working together with a scientific team at The Rockefeller University in New York, the investigators have shown that treatment with the oral anticoagulant…
Winners announced for National Institute on Aging dementia care coordination challenge
NIA’s Eureka competition awards focus on mobile apps for people with dementia, healthcare providers and caregivers
Diabetes-Alzheimer’s link explored at Neuroscience 2019
Live-streamed press conference offers breaking research
Study pinpoints Alzheimer’s plaque emergence early and deep in the brain
Long before symptoms like memory loss even emerge, the underlying pathology of Alzheimer’s disease, such as an accumulation of amyloid protein plaques, is well underway in the brain. A longtime goal of the field has been to understand where it…
MIT sets out to model Alzheimer’s disease complexity on a chip
The complexity of Alzheimer’s disease, which affects many types of cells in the brain including its blood vessels, has proven difficult to recreate in the lab. With a new $5.6 million, five-year grant from the National Institutes of Health, MIT…
Experts call for coordinated action to avert a brain disease crisis
Experts are calling for a public health campaign aimed at promoting a ‘brain-healthy lifestyle’ to reduce the risk of developing neurodegenerative brain diseases, such as Alzheimer’s disease and Parkinson’s disease. The campaign should support existing health promotion work by emphasising…
Key to learning and forgetting identified in sleeping brain
Manipulating specific brain waves in sleeping rats shifts the balance between learning or forgetting a new skill
IU School of Medicine awarded $36 million NIH grant for Alzheimer’s disease drug discovery center
The IU-led center is one of only two multi-institution teams in the nation selected as part of a new federal program intended to improve, diversify and reinvigorate the Alzheimer’s disease drug development pipeline.
National Institute on Aging awards $73 million for new Alzheimer’s drug discovery centers
Collaborating institutions will lead development of openly distributed tools to test the efficacy of Alzheimer’s therapies and share results
IU School of Medicine awarded $36 million NIH grant for Alzheimer’s drug discovery center
INDIANAPOLIS — Indiana University School of Medicine has been awarded a grant expected to total $36 million over five years from the National Institutes of Health to launch a drug discovery center to accelerate the development of promising treatments for…
A brain protein that could put the brakes on Alzheimer’s
UCI discovery heralds new directions in the disease fight
$4 million grant will test platform aimed at helping caregivers manage dementia symptoms
National Institute on Aging’s grant to Drexel College of Nursing and Health Professions will fund study on the impact of an easy-to-use, online platform called WeCareAdvisor
Researchers Receive $18 Million Grant to Study Connection Between Alzheimer’s, Dementia, and Parkinson’s Disease
A National Institute on Aging grant will support Penn’s Center for Neurodegenerative Disease Research to study the underlying genetic connections between Alzheimer’s Disease, Parkinson’s Disease, and Dementia.
Common nutrient supplementation may hold the answers to combatting Alzheimer’s disease
In a new study, Biodesign researchers reveal that a lifelong dietary regimen of choline holds the potential to prevent Alzheimer’s disease (AD). Choline is a safe and easy-to-administer nutrient that is naturally present in some foods and can be used…
Study examines alcohol consumption, risk of dementia in older adults
Bottom Line: This observational study examined alcohol consumption and the risk of dementia and cognitive decline in older adults with or without mild cognitive impairment (MCI). The study analyzed 3,021 adults (72 and older) who were free of dementia (2,548…
Latest issue of Alzheimer’s & Dementia
September 2019 journal digest
AAN recommends people 65+ be screened yearly for memory problems
MINNEAPOLIS – People with mild cognitive impairment have thinking and memory problems but usually do not know it because such problems are not severe enough to affect their daily activities. Yet mild cognitive impairment can be an early sign of…
Potential target for diabetes-associated Alzheimer’s disease
Study reveals potential mechanism underlying relationship between diabetes and dementia
Is copper a cause of Alzheimer’s disease?
University of Houston researcher examines the link
Shimmer announces launch of healthcare industry open source initiative for wearable sensor algorithm
Initiative will enable the development of industry standards for wearable sensor data
Popular mobile games can be used to detect signs of cognitive decline
New research led by the University of Kent shows that popular mobile phone games could provide a new tool to help doctors spot early signs of cognitive decline, some of which may indicate the onset of serious conditions like dementia.…
Knotty problem of cell reprogramming solved, USC scientists report
The researchers found a way to repurpose cells more reliably than current methods by untangling DNA,
RRI senior scientist elected as a fellow of the Royal Society of Canada
Dr. Cheryl Grady, a senior scientist at Baycrest’s Rotman Research Institute (RRI), has been recogni
Brain changes may help track dementia, even before diagnosis
MINNEAPOLIS – Even before a dementia diagnosis, people with mild cognitive impairment may have different changes in the brain depending on what type of dementia they have, according to a study published in the September 11, 2019, online issue of…
Researchers propose the ‘Alzheimer’s Disease Exposome’ to address environmental risks
USC and Duke researchers say the framework illustrates how environmental and genetic factors interac
New biomarker for dementia improves risk prediction
In a study of cognitively healthy adults, elevated plasma levels of IGFBP-2 were associated with an