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UrduValue in Health, the official journal of ISPOR—The Professional Society for Health Economics and Outcomes Research, announced the publication of a report that identifies expensive Medicare Part B drugs with low added therapeutic benefit and models a reimbursement policy for them based on domestic reference pricing.
Month: September 2023
X-ray Spectral Microscopy Reveals The Active Edges of a Water-Splitting Material
X-rays penetrate a working electrode to determine the structure and chemistry in play when water enters the electrochemically active layers.
Atypical antipsychotics not safer than haloperidol for older adults with postoperative delirium
A study of more than 17,000 older adults prescribed an antipsychotic medication after major surgery found that atypical antipsychotics are not less harmful than haloperidol. The findings are published in Annals of Internal Medicine.
Low-cost generic drug programs have large gaps in coverage for core evidence-based CVD medications
A cross-sectional study of 19 low-cost generic programs (LCGPs) found that their medication coverage for six cardiovascular diseases (CVD) varied significantly between programs. Of all analyzed programs, Mark Cuban Cost Plus Drug Company demonstrated the most comprehensive coverage for all diseases included in the study. The findings are published in Annals of Internal Medicine.
Pharmacy Discount Card Programs Like Amazon Prime and GoodRx Gold Could Save Patients Millions Of Dollars In Out-of-Pocket Costs For Commonly Prescribed Generic Medications
A nationally representative study found that at least one out of five prescriptions for commonly prescribed generic medications were cheaper through Amazon Prime or GoodRx Gold discount cards compared to actual out-of-pocket (OOP) payments made by patients.
Pioneering research sheds surprising new light on evolution of plant kingdom
A new study has uncovered intriguing insights into the evolution of plant biology, effectively rewriting the history of how they evolved over the past billion years.
Largest genetic study of epilepsy to date provides new insights on why epilepsy develops and potential treatments
The largest genetic study of its kind, coordinated by the International League Against Epilepsy (ILAE), has discovered specific changes in our DNA that increase the risk of developing epilepsy.
Korean Scientific payload for observing the lunar space environment begins its transfer to the US for the scheduled 2024 launch
The Ministry of Science and ICT and the Korea Astronomy and Space Science Institute announced the beginning of the transfer of the lunar space environment monitor, ‘LUSEM'(Lunar Space Environment Monitor) that will be aboard United States’ unmanned lunar lander in 2024, has began on September 4th.
Plesiosaurs doubled their neck-length by gaining new vertebrae
Plesiosaurs gained their famous long necks rapidly, researchers have shown.
New ACP paper addresses ethical issues in determining death; recommends clarification to the Uniform Determination of Death Act
The American College of Physicians (ACP) has issued a new paper addressing current controversies about the standards for determining death, supporting a clarification to the Uniform Determination of Death Act (UDDA) but otherwise reaffirming the current UDDA and the ethical principles that are its foundation. The paper is published in Annals of Internal Medicine.
Hunting for Supermassive Black Holes in the Early Universe
Supermassive black holes (SMBHs) – black holes with masses exceeding a million times that of the Sun – are known to prevail in the universe today.
Study shows making cities greener doesn’t just capture carbon – it reduces it
Dozens of European cities could reach net zero carbon emissions over the next 10 years by incorporating nature into their infrastructure, according to a new study.
Machine learning tool simplifies one of the most widely used reactions in the pharmaceutical industry
University of Illinois researchers and a Swiss pharmaceutical company have developed a machine learning model that eliminates the need for extensive experimentation to determine the best conditions for an important carbon-nitrogen bond forming reaction known as the Buchwald-Hartwig reaction.
$26M NIH grant addresses environmental influences on child health
Backed by a $26 million federal grant, researchers at three Michigan universities, a leading health care system, and a state agency will continue a long-term study of how exposure to environmental factors during pregnancy and early childhood can impact health for a lifetime. The funding from the National Institutes of Health, or NIH, is for the second phase of a national research program called ECHO, which stands for the Environmental Influences on Child Health Outcomes, and includes a sample of mothers, infants and children from across the United States. The first phase began in 2016.
Ukrainian grain farmers now raising hogs benefit from ISU expertise
Many Ukrainian farmers are raising hogs for the first time, converting cheap grain into needed meat. An Iowa State University swine health expert is helping Ukrainian farmers safely navigate the war-driven pivot to pork with a series of online workshops.
PPPL wins three major DOE awards for supercomputing fusion projects
Description of the three PPPL-led SciDAC collaborations that unite fusion scientists and and applied mathematicians to solve complex fusion problems through supercomputing.
Scientists Make the First Observation of a Nucleus Decaying into Four Particles After Beta Decay
Scientists have observed a rare new radioactive decay mode for the first time. In this decay mode, oxygen-13 (with eight protons and five neutrons) decays by breaking into three helium nuclei (an atom without the surrounding electrons), a proton, and a positron (the antimatter version of an electron) following beta decay. The findings expand scientific knowledge of decay processes and the properties of the nucleus before the decay.
UAH receives Stage 1 approval for $24.4M Bevill Center renovation to expand cybersecurity education, training and research
The University of Alabama in Huntsville (UAH) received Stage 1 approval from the University of Alabama System Board of Trustees for a $24.4 million Center for Cybersecurity Research, Education and Advanced Training. The 45,000-square-foot renovation project will establish UAH’s Bevill Center as the new home of the existing UAH Center for Cybersecurity Research and Education (CCRE), and it will modify the building to add modern classroom and training spaces, research laboratories and office space, as well as complete upgrades to the main building lobby.
Desai Sethi Urology Institute Researcher Finds “Sneaky Testosterone” Might Signal Worse Outcomes for Men with Prostate Cancer
Findings from the newly published study in The Journal of Clinical Investigation suggest a large proportion of men have testosterone concentrations that are much higher in and around the prostate than traditional blood draws suggest. And this elevated exposure near the prostate increases the risk of poor outcomes after surgical removal of the prostate gland.
Is digital media use a risk factor for psychosis in young adults?
On average, young adults in Canada spend several hours on their smartphones every day. Many jump from TikTok to Netflix to Instagram, putting their phone down only to pick up a video game controller.
Sepsis – as common as cancer, as deadly as a heart attack
In 2016, the research team conducted an initial study in southern Sweden (Skåne) where they revealed that sepsis is much more common than previously believed.
Scientists unpick how lung cells induce immune response to influenza
Researchers from Trinity College Dublin have discovered some new and surprising ways that viral RNA and influenza virus are detected by human lung cells, which has potential implications for treating people affected by such viruses.
Mapping the coronavirus spike protein could provide insight into vaccine development
Although the COVID-19 pandemic was the first time most of humanity learned of the now infamous disease, the family of coronaviruses was first identified in the mid-1960s.
Inflammation may influence weight loss surgery outcomes, new study reveals
Research funded by the National Institute for Health and Care Research (NIHR) has shown that higher levels of inflammation in the blood of patients with obesity undergoing bariatric surgery predicts poorer weight loss six months after the procedure.
Deprived teens with poor learning skills at greatest risk from email scams, says expert
Disadvantaged teenagers are at greater risk of email scams and need better protection, according to an international study published in the peer-reviewed British Journal of Educational Studies.
Rehacer el Reemplazo de la Válvula Aórtica Transcatéter ha Demostrado ser Efectivo y Seguro
Los investigadores de Cedars-Sinai son líderes en la innovación y el uso del reemplazo valvular aórtico transcatéter (TAVR) con válvulas expandibles con balón. Ahora demuestran que volver a hacer los procedimientos TAVR son seguros y eficaces en comparación con situaciones en las que pacientes con perfiles de riesgo similares se someten al mismo procedimiento por primera vez.
Study could help explain why certain brain tumors don’t respond well to immunotherapy
A study led by researchers at the UCLA Jonsson Comprehensive Cancer Center sheds new light on why tumors that have spread to the brain from other parts of the body respond to immunotherapy while glioblastoma, an aggressive cancer that originates in the brain, does not.
LJI scientists harness ‘helper’ T cells to treat tumors
La Jolla Institute for Immunology (LJI) scientists have published a pair of studies that show how we might harness CD4+ T cells while boosting the cancer-fighting power of CD8+ “killer” T cells.
Observation of nonlinear disclination states
Controllable deformations introduced in periodic structures may lead to appearance of disclinations and open new routes for construction of higher-order topological insulators with various discrete rotational symmetries, which were observed so far only in linear regime.
Infrared avalanche photodiodes from bulk to 2D materials
Avalanche photodiodes (APDs) have drawn interest in recent years and extensively used in many applications to include the most important – optical communication. Unquestionably optical quantum information applications such as quantum key distribution also drive that trend putting severe requirements on detector performance. Towards this goal the authors showed the evolution and the recent development of AIIIBV, AIIBVI and potential alternative – “third wave” superlattices and 2D materials APDs.
‘Broadband Prairie’ rural wireless project moves to public phase of researching, testing
With wireless infrastructure installed in and around Ames, Iowa, the $16 million ARA Wireless Living Lab for Smart and Connected Rural Communities is moving to a public testing phase. The progress will be celebrated with technical presentations and field trips during a launch event Sept. 6-8 on the Iowa State University campus.
Ohio State first in world to participate in trial of device designed to alleviate heart failure symptoms
The Ohio State University Wexner Medical Center on Wednesday randomized the first patient in the world in a clinical trial evaluating the effectiveness of a device designed to alleviate heart failure symptoms.
Researchers find Antarctic ice shelves thinner than previously thought
As global ice dams begin to weaken due to warming temperatures, a new study suggests that prior attempts to evaluate the mass of the huge floating ice shelves that line the Antarctic ice sheet may have overestimated their thickness.
“Countercation engineering” for thermoresponsive graphene-oxide nanosheets
Graphene-based two-dimensional materials have recently emerged as a focus of scientific exploration due to their exceptional structural, mechanical, electrical, optical, and thermal properties.
Adding immune modulator to targeted therapy does not improve survival in difficult-to-treat thyroid cancer
New study results indicate that combining two separately promising therapies for radioiodine-resistant thyroid cancer does not bring any added benefit.
American Thyroid Association® (ATA®) releases new guidance document for the safe performance, training and adoption of ablation techniques for benign thyroid nodules
The statement was drafted by a multidisciplinary, global writing task force led by co-chairs Catherine Sinclair, MD, Icahn School of Medicine at Mount Sinai and Monash University, and Jennifer H. Kuo, MD, Section of Endocrine Surgery, Department of Surgery, Columbia University.
Hackensack Meridian Mountainside Medical Group welcomes Laura Yapor, M.D.
Mountainside Medical Group has announced that Laura Yapor, M.D. has joined the practice in the field of pulmonology.
Dr. David Winter shares how ongoing heat is causing illness.
David Winter, MD, at Baylor Scott & White Health, answers the most common patient questions and reacts to the latest medical research. Are we seeing more heat-related illness because of the ongoing extreme heat? (SOT@ :14, TRT :20) Cooler weather…
Blood biomarker shows “great promise” predicting progression to Alzheimer’s disease in at-risk population
Neuroscience researchers at Wayne State University published a review article that confirms the usefulness of neurofilament light (NfL) blood levels to predict the likelihood and rate of progression of neurodegeneration in Alzheimer’s disease.
Analysis Reveals Factors Associated With Patients With Sepsis Who Require Mechanical Ventilation
An analysis of 10 years of health data showed that risk factors for needing mechanical ventilation changed for patients with newly diagnosed sepsis as more time passed after onset.
September 2023 Issue of Neurosurgical Focus: “Cervical Spondylotic Myelopathy”
Announcement of contents of the September 2023 issue of Neurosurgical Focus
Scientists Make the First Observation of a Nucleus Decaying into Four Particles After Beta Decay
For the first time, scientists observe a new and rare decay mode where oxygen-13 breaks into three helium nuclei and a proton following beta decay.