The December 2019 issue of Toxicological Sciences features research on the leading edge of toxicology, including in the areas of carcinogenesis, developmental and reproductive toxicology, and more.
Month: December 2019
Rural Women at Higher Risk of Life-Threatening Pregnancy Complications
Women in rural communities experience higher rates of life-threatening complications during or after childbirth than mothers in urban cities, a new study finds.
Water management grows farm profits
Study investigates effects of irrigation management on yield and profit
Retrospective Analysis Identifies Need for Better Classification of Rare Lymphoma
In what is believed to be one of the largest studies of a rare disorder known as primary cutaneous gamma delta T-cell lymphoma, Rutgers Cancer Institute
investigators and other collaborators examined characteristics, treatment patterns and outcomes and determined accurate diagnosis of the disease requires ongoing analysis.
Top 5 ways we can support soil
Join in celebrating World Soil Day on December 5th
CROP INNOVATION COMPANY INTRODUCES NEW SEED COMPANY FOCUSED ON HIGH-PERFORMANCE FOOD & FEED GRADE SOYBEANS
Benson Hill today announced the launch of Benson Hill Seeds, a business focused on delivering superior seeds to meet the evolving needs of the growing human food and animal feed markets, including the eMerge Genetics portfolio of non-GMO soybean varieties.
Toxic corporate workplace culture could be linked to Australia’s spiral into depression
Here’s a sobering statistic for the ‘lucky country’: 36 million prescriptions for antidepressant medication were issued in Australia in 2018, the second highest in the developed world after Iceland.
Another presidential hopeful exits the race; Duncan Hunter expected to plead guilty — University of Redlands political scientist available to comment on these and other political topics
Another presidential hopeful exits the race; Duncan Hunter expected to plead guilty — University of Redlands political scientist available to comment on these and other political issues. Dr. Renee Van Vechten is a nationally recognized expert on California politics, term…
Differences in replacement level fertility point to inequalities
The percentage of the world’s population that is above or below the ‘replacement level of fertility’ has long been used as a measure of demographic development. A new study revisited how this metric is calculated and how useful it really is in terms of informing policy decisions.
First giant planet around white dwarf found
ESO observations indicate the Neptune-like exoplanet is evaporating
Birds are shrinking as the climate warms
Forty years of data show that migratory birds have been getting smaller
Cellular repair response to treadmill test can predict cardiac outcomes
Circulating progenitor cell traffic reflects need for blood vessel repair
NOTCH1 signaling in oral squamous cell carcinoma via a TEL2/SERPINE1 axis
The cover for issue 63 of Oncotarget features Figure 6, “Inverse relationship between ETV7 and SERPINE1 in OSCC,” by Salameti, et al.
Mapping the energy transport mechanism of chalcogenide perovskite for solar energy use
Engineers have characterized the thermal energy conversion mechanism in the lattice of an advanced nanomaterial called chalcogenide perovskite and demonstrated its ‘tunability’– important for its potential use in solar energy generation
Contamination by metals can increase metabolic stress in mussels
The researchers propose that this evidence should be used as input to public policy with the aim of mitigating the impacts of human activities on coastal and marine ecosystems.
New diagnostic techniques and drug may slow and even reverse cognitive decline from aging
BEER-SHEVA, ISRAEL and BERKELEY, CALIFORNIA…DECEMBER 4, 2019 – A groundbreaking clinical approach has been developed combining new diagnostic techniques to detect a leaking blood-brain barrier (BBB) with a new anti-inflammatory drug that for the first time slows or reverses age-related…
Targeted therapy better for repeat kidney cancer patients than FDA-approved counterpart
City of Hope co-led a phase 3 clinical trial that may soon change how renal cell carcinoma patients are treated in third- and fourth-line therapies
Degrowth is the key to tackling climate change — but it won’t be easy
Atlas Award-winning study in Elsevier’s Futures journal highlights barriers we will need to overcome
Teens must ‘get smart’ about social media
Warning of effects on young adolescents
Less rice, more nutritious crops will enhance India’s food supply
Columbia Data Science Institute research finds that diversifying India’s crops could provide better nutrition for 200 million undernourished people
Medical marijuana cards often sought by existing heavy users
PISCATAWAY, NJ – Young adults who seek enrollment in state medical marijuana programs are often those who already use heavily rather than those with mental or physical issues that could be addressed by the drug. That’s according to new results…
How plants harness ‘bad’ molecules for good ends
Identifying the complex molecular interactions that regulate root growth could lead to more productive crops
Incumbent CEOs working with new CFOs earn 10% more money
Newly hired CFOs may face pressure to manage earnings to bump CEO pay
Introducing peanuts and eggs early can prevent food allergies in high risk infants
Research undertaken by King’s College London and St George’s, University of London has found that introducing certain foods early to infants can prevent them from developing an allergy despite low adherence to an introduction regime. In a series of papers…
Mobile stroke units could expedite treatment and improve patient outcomes in urban areas
Journal of the American Heart Association Report
Mindfulness training may help lower blood pressure, new study shows
PROVIDENCE, R.I. [Brown University] — As the leading cause of death in both the United States and the world, heart disease claims nearly 18 million lives every year, according to the World Health Organization. Many of these deaths are due…
Georgia State chemistry professor honored as National Academy of Inventors Fellow
ATLANTA–Jenny Yang, a Regents’ Professor of chemistry at Georgia State University and the associate director of the Center for Diagnostics and Therapeutics, has been selected as a National Academy of Inventors (NAI) Fellow, the academy board announced on Tuesday. Yang,…
Technology that unblocks airways developed by researchers at Ben-Gurion U and Cincinnati Children’s
Will aid children with respiratory tract diseases including asthma, bronchiolitis, chronic obstructive pulmonary disease, and cystic fibrosis
Once-a-month oral contraceptive could improve patient adherence
Researchers have created a new ingestible drug delivery platform that expands in the stomach and could safely deliver a contraceptive over one month when tested in pigs. The technology could one day help women adhere more easily to birth control…
How race is associated with differences among patients with hypertrophic cardiomyopathy
What The Study Did: Researchers in this observational study looked at how race was associated with difference in symptoms, access to care, genetic testing and clinical outcomes among 2,467 patients (8.3% black and 91.7% white) with hypertrophic cardiomyopathy, a condition…
Alzheimer’s Drug Discovery Foundation’s Diagnostics Accelerator announces second round of awards
$50 million global research initiative, funded by Leonard A. Lauder, Bill Gates, Jeff and MacKenzie Bezos, among other leading philanthropists, targets resources to speed up development of blood, digital and other biomarkers for early detection
Getting to the ‘art’ of dementia: UC researchers highlight benefits of art intervention
University of Canberra researchers have shown that art gallery programs can improve the wellbeing of people living with dementia – and they’ve backed it up by testing study participants’ saliva. Published in the Journal of Alzheimer’s Disease , the UC…
Scientists have found out why photons flying from other galaxies do not reach the Earth
An international group of scientists, including Andrey Savelyev, associate professor of the Institute of Physical and Mathematical Sciences and Information Technologies of the IKBFU, has improved a computer program that helps simulate the photons
Deep biomarkers of aging and longevity: From research to applications
The deep age predictors can help advance aging research by establishing causal relationships in nonlinear systems.
Brewing beer that tastes fresh longer
Unlike wine, which generally improves with time, beer does not age well. Usually within a year of bottling, the beverage starts to develop an unpleasant papery or cardboard-like flavor that drinkers describe as “stale.” Now, researchers reporting in ACS’ Journal…
A mouse model of prostate cancer bone metastasis in a syngeneic immunocompetent host
The cover for issue 64 of Oncotarget features Figure 5, ‘In vivo and ex-vivo growth kinetics of B6CaP,’ by Simons, et al.
Atmospheric chemists move indoors
Most people spend the majority of their time at home, yet little is known about the air they breathe inside their houses. That’s why some atmospheric chemists are turning their attention toward indoor air, using tools developed for monitoring pollutants…
Closest-ever approach to the sun gives new insights into the solar wind
The Parker Solar Probe spacecraft, which has flown closer to the Sun than any mission before, has found new evidence of the origins of the solar wind. NASA’s Parker Solar Probe was launched in August 2018. Its first results are…
Internists concerned proposed Ohio legislation would harm patients
Washington, DC (December 4, 2019) –The American College of Physicians (ACP) fears that recent legislation introduced in the Ohio state legislature that orders physicians to re-implant ectopic pregnancies, which is clinically not possible, will threaten patient health and subject physicians…
A new way to measure long-term firm performance and shareholder value
INSEAD and Wharton introduce LIVA: A metric that gauges the true impact of investment or strategic action on shareholder value
Silverswords may be gone with the wind
A rare, iconic Hawai’ian plant faces hardships as climate change affects trade winds
Moffitt’s top blood cancer research highlighted at ASH Meeting
The cancer center has 37 presentations during the conference
Call for cooperation as ‘blue boats’ rob Pacific reefs
A flotilla of Vietnamese fishing boats with crews suffering in harsh conditions is stripping Pacific coral reefs of seafood as the poaching escalates to become an international human rights and security issue. Dr Andrew Song, joint ARC Centre of Excellence…
The wellbeing connection
Germany uses ecosystems in distant, often poorer regions
Police killings of unarmed black Americans may have health impacts for nearby unborn black infants
Police violence and the health of black infants
GW-led consortium receives $2.2 million grant to fund BioCompute Object Specification Project
The BioCompute Object Specification Project works to standardize genomic data analysis
Tel Aviv University’s Prof. Carmit Levy receives Young Investigator Award from SMR
Researcher honored for major contributions to the field of melanoma research
Health care in baboons
Sexually transmitted diseases are widespread among animals and humans. Humans, however, know a multitude of protective and hygienic measures to protect themselves from infection. An international research team led by scientists at the German Primate Center (DPZ) – Leibniz Institute…
A big step toward curbing graft-vs.-host disease after bone marrow transplant
Abatacept, currently used for arthritis, gains FDA Breakthrough Therapy Designation for acute GVHD prevention
Once-a-month oral contraceptive pill in development
Investigators designed a capsule that can be swallowed once a month, reside in the stomach and release a drug to prevent pregnancy