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UrduESMO 2019 Congress, Sept. 27 — Oct. 1, Barcelona, Spain
Tag: PHARMACEUTICAL SCIENCES
GARDP and Entasis Therapeutics initiate global phase 3 trial of zoliflodacin
The Global Antibiotic Research and Development Partnership (GARDP), a not for profit organisation developing new treatments for drug resistant infections, and Entasis Therapeutics (NASDAQ: ETTX), a clinical-stage biopharmaceutical company focused on the discovery and development of novel antibacterial products, today…
AI system accurately detects key findings in chest X-rays of pneumonia patients within 10 seconds
From 20 minutes or more to 10 seconds. Researchers from Intermountain Healthcare and Stanford University say 10 seconds is about how quickly it took a new system they studied that utilizes artificial intelligence to accurately identify key findings in chest…
First prostate cancer therapy to target genes delays cancer progression
Genetic-based treatment nearly doubles time without disease progression in metastatic prostate cancer
Immune therapy eliminates tumour cells in early triple negative breast cancer
ESMO 2019 Congress, Sept. 27 – Oct. 1, 2019, Barcelona, Spain
Two studies show CDK4/6 inhibitors improve overall survival in advanced breast cancer
ESMO 2019 Congress, Sept. 27 – Oct. 1, 2019, Barcelona, Spain
US government backs Sydney spinout company Kinoxis Therapeutics to fight opioid addiction
Funding to support development of a potential treatment for opioid withdrawal
One in two pts with metastatic melanoma alive after 5 years with combination immunotherapy
ESMO 2019 Congress, Sept. 27 – Oct. 1, Barcelona, Spain
Front-line osimertinib improves overall survival in EGFR-mutation positive NSCLC
ESMO 2019 Congress, Sept. 27, 2019 – Oct. 1, 2019, Barcelona, Spain
Ovarian cancer: more women benefit from maintenance combined targeted therapy
ESMO 2019 Congress, Sept. 27 – Oct. 1, 2019, Barcelona, Spain
Lipid produced by organism helps control blood sugar
Blood sugar levels in obese mice were controlled more efficiently when the mice were challenged with a glucose overload and treated with 12-HEPE, a lipid produced in response to cold by brown adipose tissue.
Extra amino acid could work wonders
Rice University chemist uses designer amino acids in search for new cures
Cancer tumours form surprising connections with healthy brain cells
Healthy neurons form synapses with aggressive brain cancer cells that stimulate the growth and proliferation of brain cancer; anti-epileptic medicine can curb the dangerous communication and possibly be part of future treatment, a Norwegian study shows
Genetic markers linked to the start of symptoms of Parkinson’s disease
New therapeutic targets
Tasmanian devil research could help tackle immunotherapy resistance
A cluster of interacting proteins that are active in both human cancers and Tasmanian devil facial tumours, may give clues to how cancers evade the immune system, according to a study part-funded by Cancer Research UK and published in Cancer…
NIST goes with the (slow) flow: New technique could improve biotech, precision medicine
Researchers at the National Institute of Standards and Technology (NIST) have developed an optical system that accurately measures the flow of extraordinarily tiny amounts of liquids — as small as 10 billionths of a liter (nanoliters) per minute. At that…
New fungus-derived antibiotic: relief in sight for immunocompromised people
Scientists derive a new compound from eushearilide, which can potentially take on lethal fungal and bacterial infections
Temple scientists solve mystery underlying heart toxicity caused by diabetes drugs
(Philadelphia, PA) – Like catching two fish with one worm, treating two problems with a single drug is efficient, but exceedingly difficult. In particular, for new diabetes medications, in which one drug aims to tackle two major complications of diabetes…
EBook series, ‘Anti-Obesity Drug Discovery and Development’, indexed in Scopus
‘Anti-Obesity Drug Discovery and Development’, book series published by Bentham eBooks, has been accepted for inclusion in Scopus. Scopus is the largest abstract and citation database of peer-reviewed literature including scientific journals, books and conference proceedings. Obesity is a complex…
Discovery of novel cancer signaling mechanism and design of new anticancer compound
Using a newly synthesized compound and advanced immunofluorescence techniques, scientists uncover novel signaling mechanism in cancer and also propose new channel of treatment
Leukemia Drug Shows Promise for Treating a Childhood Brain Cancer
Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego researchers describe new use of leukemia drug, nilotinib, to treat subtype of medulloblastoma, a deadly pediatric brain cancer.
AI-guided robotics enable automation of complex synthetic biological molecules
Overcomes bottlenecks of time-consuming, labor-intensive manufacturing processes
Novel anti-cancer nanomedicine for efficient chemotherapy
Researchers at the University of Helsinki in collaboration with researchers from Åbo Akademi University,Finland and Huazhong University of Science and Technology,China have developed a new anti-cancer nanomedicine for targeted cancer chemotherapy. This new nano-tool provides a new approach to use…
Researchers find building mutations into Ebola virus protein disrupts ability to cause disease
ATLANTA–Creating mutations in a key Ebola virus protein that helps the deadly virus escape from the body’s defenses can make the virus unable to produce sickness and activate protective immunity in the infected host, according to a study by the…
Turbo-charging pharmaceutical biotechnology simulations
Demand for biopharmaceuticals is strong: biopharmaceutical active ingredients – in other words, genetically engineered drugs – accounted for seven of the ten top-selling medications in the world in 2018. And the proportion is set to rise, as biopharmaceuticals can be…
TTUHSC researchers to investigate effects of vaping on the brain
For the past decade, the popularity of electronic cigarette use, or vaping, has grown significantly, especially among adolescents and former smokers who view these electronic nicotine delivery systems, or e-cigarettes, as a safe alternative to traditional tobacco smoking. Though the…
Researchers develop chemical reaction method for more efficient drug production
Researchers at Tokyo University of Agriculture and Technology (TUAT) in Japan and Mount Allison University in Canada have developed a more efficient method to produce the building blocks needed for antibiotics and cancer treatment drugs. They published their peer-reviewed results…
Search tightens for genes driving prostate cancer
The National Cancer Institute (NCI) is set up to fund individual projects in fields like genomics, computational biology, and pathology. Now researchers at University of Colorado Cancer Center are taking advantage of an innovative new program in cancer systems biology…
Medication adherence may affect risk of hospitalization and early death
A recent analysis of published studies examined the clinical consequences of medication adherence. The British Journal of Clinical Pharmacology analysis found that medication adherence is linked with lower risks of needing to be hospitalised and of dying early. Individuals aged…
Should patients continue blood thinners after experiencing gastrointestinal bleeding?
Anticoagulants and antiplatelet drugs, which are blood thinners such as warfarin and aspirin, are commonly taken to reduce the risk of potentially fatal blood clots, but they carry an increased risk of gastrointestinal bleeding. A study of 871 patients from…
Michael A. Petr to present at the 6th Annual Aging Research, Drug Discovery, and AI Forum in Basel
Thursday, September 5, 2019 – Today the Biogerontology Research Foundation , a leading UK non-profit foundation dedicated to increasing healthy longevity and promoting advances in ageing research, Insilico Medicine , a biotechnology company developing the end-to-end drug discovery pipeline utilizing…
Scientists confirm efficacy of a combination therapy for advanced liver cancer
A procedure that cuts off blood supply to tumors improves the effectiveness of a drug for advanced-s
UTA scientist explores using nanoparticles to reduce size of deep-seated tumors
Another collaborative project from a nanoparticles expert at The University of Texas at Arlington has yielded promising results in the search for more effective, targeted cancer treatments. Wei Chen, in collaboration with colleagues from the University of Rhode Island and…
Ageing research to accelerate with experimental validation in AI-powered drug discovery
Biogerontology Research Foundation scientists have developed and experimentally-validated a new AI e
80% cut in antibiotics entering Thames is needed to avoid surge in superbugs
Modelling study estimates extent of river’s exposure to antibiotic-resistant bacteria
Comparing opioid prescription fills after surgery across countries
Bottom Line: Higher proportions of patients in the United States and Canada filled opioid prescriptions after surgery compared with Sweden. This analysis examined differences in rates of opioid prescriptions filled after low-risk surgical procedures (laparoscopic removal of the gallbladder or…
ASNC announces multisocietal cardiac amyloidosis consensus
The American Society of Nuclear Cardiology (ASNC) publishes ‘Expert Consensus Recommendations For Mu
Negotiation: A three-step solution to affordable prescription drugs
Harvard University and George Mason University professors’ — Drs. Richard G. Frank and Len M. Nicho
LSU Health New Orleans awarded $13.6 million for expanded cancer clinical trials network
New Orleans, LA – LSU Health New Orleans has been awarded a $13.6 million grant by the National Cancer Institute to expand its successful statewide clinical trials network with a special emphasis on minority and underserved cancer patients. Principal Investigator…
Pharmacists in the ER speed delivery of coagulation drug to bleeding patients
MAYWOOD, IL – Millions of patients take blood thinners such as Coumadin to prevent blood clots that can cause strokes. But when such patients come to the emergency department (ED) with life-threatening bleeding, they may require a drug that counteracts…
A breakthrough in imaginative AI with experimental validation to accelerate drug discovery
A breakthrough in imaginative artificial intelligence resulting in the creation of novel molecules a
Novel approach leads to potential sepsis prevention in burn patients
Study demonstrates possibility of treating antibiotic-resistant pseudomonas aeruginosa
Cannabis may hold promise to treat PTSD but evidence lags behind use
As growing numbers of people are using cannabis to treat post-traumatic stress disorder (PTSD), a new UCL study reports that prescriptions are not backed up by adequate evidence. The systematic review, published in the Journal of Dual Diagnosis , finds…
Does appointment time influence primary care opioid prescribing?
Bottom Line: Physicians at primary care appointments were more likely to prescribe opioids for pain later in the day and as appointments ran more behind schedule, although the absolute difference in the prescribing rate across the day was modest in…
$2M from NIH to extract meaningful data from CRISPR screens
Protein-coding genes comprise a mere 1% of DNA. While the other 99% of DNA was once derided as “junk,” it has become increasingly apparent that some non-coding genes enable essential cellular functions. Wei Li, Ph.D., a principal investigator in the…
How to practice safer sunscreening
Toxicity screening of cosmetics, sunscreens and pharmaceuticals is made easier with microfluidic dev
One-third of pre-approved prescription drugs have not completed the FDA approval process
CATONSVILLE, MD, August 26, 2019 – The Food and Drug Administration’s (FDA) Accelerated Approval Program was created in 1992 to significantly accelerate the ability to bring certain new drugs to market. New research to be published in an upcoming issues…
New paper creates omega-3 calculator for researchers to specify EPA+DHA doses in studies
Certain EPA+DHA doses are needed to achieve a healthy omega-3 index and meet study endpoints
Grant awarded to MDI Biological Laboratory scientist James A. Coffman, Ph.D.
Will support research on genes governing the health effects of chronic stress
The technology behind Bitcoin may improve the medications of the future
BLOCKCHAIN. Researchers at the University of Copenhagen have developed a prototype of an app that may potentially prescribe the optimal dose of medicine for the individual patient, as well as prevent counterfeit products. Big data. Machine Learning. Internet of Things.…