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UrduAn interdisciplinary team of medical and engineering researchers has spent the last six years working to unlock a significant piece of the puzzle in the search for a cure: how and where the gluten response begins.
Tag: Autoimmune Disorders
Microrobot-packed pill shows promise for treating inflammatory bowel disease in mice
Engineers at the University of California San Diego have developed a pill that releases microscopic robots, or microrobots, into the colon to treat inflammatory bowel disease (IBD). The experimental treatment, given orally, has shown success in mice.
COVID-19 associated with increased risk for autoimmune inflammatory rheumatic diseases up to a year after infection
A large, binational study found that SARS-CoV-2 infection was associated with an increased risk for autoimmune inflammatory rheumatic diseases (AIRDs) that extends up to 12 months after infection. The risk was found to be higher with greater severity of acute COVID-19, even among those who were vaccinated. These findings suggest that care strategies for patients who survive COVID-19 should pay close attention to manifestations of AIRD, particularly after severe illness. The study is published in Annals of Internal Medicine.
Autoimmune disease and pregnancy
For many aspiring mothers with autoimmune disease, pregnancy can be daunting and full of unknowns.
The double face of RNase as a treatment for systemic autoimmune diseases
Systemic autoimmune diseases are characterized by inflammation of multiple organs and can have devastating consequences for patients. There is a dire need for treatments against these diseases.
A common metabolite may help treat autoimmune diseases
Researchers have revealed the modulatory effect of the anti-inflammatory metabolite itaconate on T helper and T regulatory cells, which may lead to new therapeutic approaches to treating some autoimmune diseases.
Putting out “the fire in the brain”
In autoimmune encephalitis, a rare but serious and sometimes life-threatening inflammation of the central nervous system, the body’s own defences are directed against the central nervous system.
Researchers ID Kidney Pathway Involved with Autoimmune-related Hypertension in Female Mice
Article title: Renal TLR-7/ TNF-α pathway as a potential female-specific mechanism in the pathogenesis of autoimmune-induced hypertension Authors: Sarika Chaudhari, Bradley M. D’Souza, Jessica Y. Morales, Cassandra M. Young-Stubbs, Caroline G. Shimoura, Rong Ma, Keisa W. Mathis From the authors:…
Celine Dion announced she has stiff-person syndrome. What is it? @UofUHealth expert available
Legendary singer Celine Dion recently canceled an upcoming tour, indicating it is due to a diagnosis of stiff-person syndrome. Stacey Clardy, MD, PhD, an autoimmune immunologist and associate professor of neurology at University of Utah Health, has published on the…
Mount Sinai Microbiome Lab Joins NIH’s Accelerating Medicines Partnership
The National Institutes of the Health (NIH) has awarded researchers at the Icahn School of Medicine at Mount Sinai a four-year grant to study the role of the human microbiome in rheumatoid arthritis, systemic lupus, and other autoimmune diseases. The grant is part of the NIH’s Accelerating Medicines Partnership® Autoimmune and Immune-Mediated Diseases (AMP® AIM) program, which is designed to speed the discovery of new treatments and diagnostics. It will support the Microbiome Technology and Analytic Center Hub (Micro-TEACH), a multidisciplinary team of researchers at Icahn Mount Sinai and NYU Langone Health.
Researchers Identify Potential Target for Treating Autoimmune Diseases
New research using a mouse model for multiple sclerosis has uncovered a potential new area to explore for possible treatments for autoimmune disorders.
DNA Analysis Provides Insight into Associations Between Worse COVID and Other Conditions
Through analyzing human DNA samples in a large biobank, Penn Medicine researchers found associations between genetic variants with severe COVID and conditions involving blood clots and respiratory issues
Study explores sleep apnea, autoimmune disease link
New research by University of Georgia scientists sheds light on why people with obstructive sleep apnea may have associated autoimmune disorders. The results could lead to better approaches to treatment and possibly new drug therapies.
Sex, Genes and Vulnerability
New work led by researchers in the Blavatnik Institute at Harvard Medical School and at the Broad Institute of MIT and Harvard provides a clear genetic explanation behind the long-standing yet mysterious observation that some diseases occur more often, hit harder or elicit different symptoms in men or women.
Research News Tip Sheet: Story Ideas From Johns Hopkins
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every Tuesday throughout the duration of the outbreak.
Autoimmunity may be rising in the United States
Autoimmunity, a condition in which the body’s immune system reacts with components of its own cells, appears to be increasing in the United States, according to scientists at the National Institutes of Health and their collaborators.
Joslin Research Ties Autoimmunity-Associated Heart Dilation to Potential Heart-Failure Risk in Type 1 Diabetes
There’s a higher case fatality rate in type 1 than type 2 diabetes, which suggests different mechanisms for heart failure might be involved in type 1 diabetes.” Given the burden of heart failure in type 1 diabetes, the early identification of patients at particular risk is of importance.
Multi-sensor Band Quickly and Simply Records Subtle Changes in Patients with MS
An international team of scientists, led by UC San Diego researchers, has developed a new, multi-sensor tool that measures subtle changes in multiple sclerosis patients, allowing physicians to more frequently and more quickly respond to changes in symptoms or patient condition.