Glucose wears down circadian clocks in obesity, may drive cardiovascular risk

AUGUSTA, Ga. (Oct. 22, 2019) – High glucose in obesity appears to gum up the works of the circadian clocks inside our cells that help regulate the timing of many body functions across the 24-hour day and drive the risk…

Data mining applied to scholarly publications to finally reveal Earth’s biodiversity

At a time when a million species are at risk of extinction, according to a recent UN report, ironically, we don’t know how many species there are on Earth, nor have we noted down all those that we have come…

New NIH BRAIN Initiative awards accelerate neuroscience discoveries

Scientists have been developing astounding new tools for exploring neural circuits that underlie brain function throughout the first five years of the National Institutes of Health’s Brain Research through Advancing Innovative Neurotechnologies® (BRAIN) Initiative. Now, the NIH has announced its…

Startled fish escape using several distinct neuronal circuits

A fast knee-jerk “ballistic” escape response and a more considered “delayed” escape response are mediated by distinct and parallel neuronal pathways in zebrafish, according to a study published October 15 in the open-access journal PLOS Biology by Harold Burgess of…

Vaccine to Block Digestive Hormone May Slow Growth of Pancreatic Cancer

New research suggests a vaccine that blocks a digestive hormone may slow the spread of pancreatic cancer, potentially increasing survival rates. The study, published ahead of print in the American Journal of Physiology—Gastrointestinal and Liver Physiology, was chosen as an APSselect article for October.

Biomedical Engineering Society names Weiqiang Chen a 2019 Young Innovator

BROOKLYN, New York, Thursday, October 10, 2019 – The Biomedical Engineering Society has named Weiqiang Chen, assistant professor of mechanical and aerospace engineering and of biomedical engineering at the NYU Tandon School of Engineering, a 2019 Young Innovator of Cellular…

Deep3DFly: the deep-learning way to design fly-like robots

“Just think about what a fly can do,” says Professor Pavan Ramdya, whose lab at EPFL’s Brain Mind Institute, with the lab of Professor Pascal Fua in EPFL’s Institute for Computer Science, led the study. “A fly can climb across…

Scientists find gender-distinct circuit for depression

EAST LANSING, Mich. – Depression affects women nearly twice as much as men, but unraveling the brain’s blueprint that regulates this behavior, let alone identifying specific molecular differences between sexes, has proven difficult. Michigan State University researchers, however, have found…

2019 Nobel Prize: APS Congratulates New Laureates Kaelin, Ratcliffe and Semenza

The 2019 Nobel Prize in Physiology or Medicine has been awarded to William G. Kaelin Jr., Peter J. Ratcliffe and Gregg L. Semenza for their work on how cells sense and adapt to oxygen availability. The American Physiological Society (APS) congratulates the winners for their discoveries and contributions to the understanding of the use and regulation of oxygen.

Blocking a Hormone’s Action in Immune Cells May Reduce Heart Disease Risk

Blocking the mineralocorticoid receptor (MR)—a protein that helps maintain normal levels of salt and water in the body—in immune cells may help reduce the risk of heart attack and stroke by improving blood vessel health. The study will be presented today at the American Physiological Society (APS) Aldosterone and ENaC in Health and Disease: The Kidney and Beyond Conference in Estes Park, Colo.

Study pinpoints Alzheimer’s plaque emergence early and deep in the brain

Long before symptoms like memory loss even emerge, the underlying pathology of Alzheimer’s disease, such as an accumulation of amyloid protein plaques, is well underway in the brain. A longtime goal of the field has been to understand where it…

Researchers discover a new defensive mechanism against bacterial wound infections

Wound inflammation which results in impaired wound healing can have serious consequences for patients. Researchers from Charité – Universitätsmedizin Berlin have discovered a new defensive mechanism which enables our skin to actively kill bacteria. Central to this mechanism is a…

Short-term Probiotics Regimen May Help Treat Gout, Kidney Disease

New research suggests that an individualized probiotic therapy regimen may improve symptoms of gout, gout-related kidney disease and other signs of metabolic syndrome. The study will be presented today at the American Physiological Society (APS) Aldosterone and ENaC in Health and Disease: The Kidney and Beyond Conference in Estes Park, Colo.

MIT sets out to model Alzheimer’s disease complexity on a chip

The complexity of Alzheimer’s disease, which affects many types of cells in the brain including its blood vessels, has proven difficult to recreate in the lab. With a new $5.6 million, five-year grant from the National Institutes of Health, MIT…

Amputees merge with their bionic leg

Djurica Resanovic lost his leg in a motorbike accident several years ago which resulted in amputation above the knee. Thanks to novel neuroprosthetic leg technology, Resanovic was successfully merged with his bionic leg during clinical trials in Belgrade, Serbia. “After…

AI system accurately detects key findings in chest X-rays of pneumonia patients within 10 seconds

From 20 minutes or more to 10 seconds. Researchers from Intermountain Healthcare and Stanford University say 10 seconds is about how quickly it took a new system they studied that utilizes artificial intelligence to accurately identify key findings in chest…