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UrduUTHealth Houston’s Movement Disorders and Neurodegenerative Diseases Fellowship Training Program (UTMOVE fellowship program) has been chosen by The Michael J. Fox Foundation for Parkinson’s Research (MJFF) as one of eight international academic centers to train a new movement disorder clinician-researcher — a neurologist with additional training and expertise in diagnosing and treating Parkinson’s and related diseases — as part of the Edmond J. Safra Fellowship in Movement Disorders Class of 2025.
Tag: Parkinson’s Disease
April is Parkinson’s Disease Awareness Month
Parkinson’s Disease Awareness month is dedicated to raising awareness and support for patients suffering from this progressive brain disorder. Learn more about Parkinson’s disease, treatment options and support for those with Parkinson’s.
Vascular Defects Appear to Underlie the Progression of Parkinson’s Disease
In an unexpected discovery, Georgetown University Medical Center researchers have identified what appears to be a significant vascular defect in patients with moderately severe Parkinson’s disease. The finding could help explain an earlier outcome of the same study, in which the drug nilotinib was able to halt motor and non-motor (cognition and quality of life) decline in the long term.
Study: Death Rate from Parkinson’s Rising in U.S.
A new study shows that in the last two decades the death rate from Parkinson’s disease has risen about 63% in the United States. The research is published in the October 27, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study also found that the death rate was twice as high in men as in women, and there was a higher death rate in white people than other racial/ethnic groups.
UC San Diego-Led Team Receives $9M to Advance Parkinson’s Disease Treatments
A new $9 million grant from Aligning Science Across Parkinson’s (ASAP) will enable advancement of UC San Diego’s discovery that inhibiting a single gene in mice converts other cell types directly into new neurons, alleviating all Parkinson’s symptoms.
Early-Stage Drug Candidate Diminishes Deficits in Parkinson’s Disease
University of Utah Health scientists have identified a molecule that slows cells’ production of alpha-synuclein, a protein that forms toxic aggregates in the brains of people with Parkinson’s disease. Its discovery points toward a new strategy for treating the disease and potentially stopping its progression.
Nasal Drugs Show Promise for Slowing Parkinson’s Disease Progression in Lab Study
Rush researchers have shown that two lab-developed and nasally-delivered peptides helped slow the spread of alpha-synuclein in mice.
UF, UF Health announce gift and new $75 million initiative to expand Norman Fixel Institute
The University of Florida and UF Health on Tuesday, Sept. 14, announced an additional $25 million gift from the Lauren and Lee Fixel Family Foundation aimed at improving the lives of patients across the globe through the Norman Fixel Institute for Neurological Diseases at UF Health. The new investment will spur growth in the areas of national and international telemedicine, Alzheimer’s disease clinical research, mental health, traumatic brain injury and ALS and will help cultivate the next generation of expert researchers tackling these challenging diseases.
Jersey Shore University Medical Center Welcomes Shabbar Danish, MD, as Chair of Neurosurgery
Hackensack Meridian Jersey Shore University Medical Center recently welcomed Board Certified Neurosurgeon Shabbar F. Danish, M.D., FAANS, as Chair of Neurosurgery as part of the academic medical center’s Neuroscience Institute.
People with Parkinson’s May Benefit from 7 Walking Strategies
Various strategies can help people with Parkinson’s who have difficulty walking, but a new study finds that many people have never heard of or tried these strategies. The research is published in the September 8, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study also found that how well different compensation strategies worked depended on the context in which they were used, such as indoors versus outdoors, under time pressure or not.
New Study Provides Structural Insights into How Cholesterol in the Brain Regulates Ion Channels and Alters Their Function; Findings Could Facilitate the Development of Therapeutics for Neurological Diseases
UNDER EMBARGO UNTIL 11am EST on August 24: Cell Reports Senior Author: Paul A. Slesinger, PhD, Lillian and Henry M. Stratton Professor of Neuroscience and Director of the Center for Neurotechnology and Behavior, Icahn School of Medicine at Mount Sinai,…
Hopkins Med News Update
NEWS STORIES IN THIS ISSUE:
-Study: Race and Ethnicity May Impact Prevalence and Treatment of Heart Valve Dysfunction
-Johns Hopkins Medicine Suggests Eliminating Nerve Cell Protein May Stop ALS, Dementia
-Researchers Tell Doctors to Avoid Routine Urinary Tests for Older Patients with Delirium
-Johns Hopkins Medicine Researchers Show How Air Pollution May Cause Chronic Sinusitis
-Researchers ID Location on Brain Protein Linked to Parkinson’s Disease Development
-COVID-19 News: The Return of Onsite Schooling — and How to Keep Your Kids Safe from COVID
Fruit Compound May Have Potential to Prevent and Treat Parkinson’s Disease, Mouse Study Suggests
Johns Hopkins Medicine researchers say they have added to evidence that the compound farnesol, found naturally in herbs, and berries and other fruits, prevents and reverses brain damage linked to Parkinson’s disease in mouse studies.
Device cracks milk protein
‘Refolding’ molecules to support medical solutions
Parkinson’s disease: How lysosomes become a hub for the propagation of the pathology
Over the last few decades, neurodegenerative diseases became one of the top 10 global causes of death. Researchers worldwide are making a strong effort to understand neurodegenerative diseases pathogenesis, which is essential to develop efficient treatments against these incurable diseases.…
Digital health technologies hold key to new Parkinson’s treatments
Global stakeholders come together to collaborate with urgency to address unmet needs for Parkinson’s therapies
Digital technology driving tangible advancements in Parkinson’s disease research and clinical care
In this new supplement to the Journal of Parkinson’s Disease experts report on how digital technology is being used to reshape research and clinical care in Parkinson’s disease
Chemists Found an Effective Remedy For “Aged” Brain Diseases
Russian scientists have synthesized chemical compounds that can stop the degeneration of neurons in Alzheimer’s, Parkinson’s, and other severe brain pathologies.
A Trojan horse could help get drugs past our brain’s tough border patrol
Sclerosis, Parkinson’s Disease, Alzheimer’s and epilepsy are but a few of the central nervous system disorders. They are also very difficult to treat, since the brain is protected by the blood-brain barrier. The blood-brain barrier works as a border wall…
UCPH researchers prove powerhouse malfunction as the major cause of Parkinson’s Disease
12,000 people in Denmark and 7 to 10 million people worldwide suffer from Parkinson’s Disease (PD). It is the second most common neurogenerative disorder of aging and the most common movement disorder, but the cause of the disease is largely…
Identified an early neuronal dysfunction in Parkinson’s that could help early diagnosis
Researchers from IDIBELL and the University of Barcelona (UB) have described that neurons derived from Parkinson’s patients show impairments in their transmission before neurodegeneration.
Dancing with music can halt most debilitating symptoms of Parkinson’s disease
A new study published in Brain Sciences today, shows patients with mild-to-moderate Parkinson’s disease (PD) can slow the progress of the disease by participating in dance training with music for one-and-a-quarter hours per week.
New Alzheimer’s treatment targets identified
A research team at Washington University School of Medicine in St. Louis has identified potential new treatment targets for Alzheimer’s disease, as well as existing drugs with therapeutic potential.
Brain mapping method illuminates targets for treating neuropsychiatric symptoms
Novel approach finds targets for future clinical trials in depression and Parkinson’s disease
Identified an early neuronal dysfunction in Parkinson’s that could help early diagnosis
Researchers from IDIBELL and the University of Barcelona (UB) have described that neurons derived from Parkinson’s patients show impairments in their transmission before neurodegeneration. For this study, it has been used dopaminergic neurons differentiated from patient stem cells as a…
Dancing with music can halt most debilitating symptoms of Parkinson’s disease
First-of-its-kind York U study shows participating in weekly dance training improves daily living and motor function for those with mild-to-moderate Parkinson’s
Adult ADHD is linked to numerous physical conditions
Adults with ADHD are at higher risk of a wide range of physical conditions, including nervous system, respiratory, musculoskeletal, and metabolic diseases, according to a large register-based study from Karolinska Institutet in Sweden published in The Lancet Psychiatry . “Identifying…
Engineered Neural Networks Help ID Responses Associated with Abnormalities in Parkinson’s Disease
Article title: Early functional changes associated with alpha-synuclein proteinopathy in engineered human neural networks Authors: Vibeke D. Valderhaug, Kristine Heiney, Ola Huse Ramstad, Geir Bråthen, Wei-Li Kuan, Stefano Nichele, Axel Sandvig, Ioanna Sandvig From the authors: “In this study, we investigate the…
Discovery of nanosized molecules that might inhibit Alzheimer’s and Parkinson’s diseases
Nanosized molecules of a particular chemical element can inhibit the formation of plaque in the brain tissues.
Discovery of nanosized molecules that might inhibit Alzheimer’s and Parkinson’s diseases
Nanosized molecules of a particular chemical element can inhibit the formation of plaque in the brain tissues. This new discovery by researchers at Umeå University, Sweden, in collaboration with researchers in Croatia and Lithuania, provides renewed hope for novel treatments…
Henry Ford Health System Therapeutic Choir Finds Its Voice Through COVID-19
DETROIT – Henry Ford Health System is using the healing power of singing to help patients with voice disorders that result from various medical conditions such as Parkinson’s disease, stroke and vocal cord paralysis to help improve their voices. Patients in a therapeutic choir called the Motor City Upbeats regain their vocal strength and range and breathing through a series of simple exercises and techniques taught in a welcoming, cheerful environment where just hearing the sound of your voice is music to the ears.
Will reduction in tau protein protect against Parkinson’s and Lewy body dementias?
A study suggests that reducing tau protein in brain neurons will not protect against Parkinson’s disease and Lewy body dementias. If borne out, this result differs from Alzheimer’s disease, where reducing endogenous tau levels in brain neurons is protective for multiple models of the disease.
The ISSCR 2021 Annual Meeting starts 21 June
Six days of exceptional stem cell science
Alzheimer disease research results over-hyped if science papers omit mice from the title
Scientists call for accurate reporting of animal studies to avoid misleading the public with exaggerated news headlines
Two decade analysis of African neuroscience research prompts calls for greater support
With the world’s largest human genetic diversity, experts believe Africa is vital to help progress neuroscience research
New study gives clue to the cause, and possible treatment of Parkinson’s Disease
Zebrafish model research reveals clues about molecular triggers of Parkinson’s Disease
Understanding gut inflammation may hold clues to mitigating Parkinson’s onset
GRAND RAPIDS, Mich. (JUNE 8, 2021) — Chronic inflammation in the gut may propel processes in the body that give rise to Parkinson’s disease, according to a study by scientists at Van Andel Institute and Roche. The study, published in…
Understanding gut inflammation may hold clues to mitigating Parkinson’s onset
GRAND RAPIDS, Mich. (JUNE 8, 2021) — Chronic inflammation in the gut may propel processes in the body that give rise to Parkinson’s disease, according to a study by scientists at Van Andel Institute and Roche.
Simple blood test can accurately reveal underlying neurodegeneration
A single biomarker can accurately indicate the presence of underlying neurodegeneration in people with cognitive issues
The Mathematical Model of the Mind
‘A must read for anyone interested in theoretical studies of cortical microcircuits’
Studies reveal skull as unexpected source of brain immunity
Immune cells from skull bone marrow guard the brain, spinal cord
After 15 Years, Deep Brain Stimulation Still Effective in People with Parkinson’s
Deep brain stimulation continues to be effective in people with Parkinson’s disease 15 years after the device is implanted, according to a study published in the June 2, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology. Researchers found that compared to before deep brain stimulation, study participants continued to experience significant improvement in motor symptoms, which are symptoms that affect movement, as well as a reduction in medications 15 years later.
Deciphering Gene-Environment Interactions in Parkinson’s Disease
The interaction between an individual’s genetics and their local environment plays a critical role in an individual’s likelihood of getting Parkinson’s disease. In this perspective, researchers highlight how a common fly could be used to better understand the complex interactions…
After 15 years, deep brain stimulation still effective in people with Parkinson’s
MINNEAPOLIS – Deep brain stimulation continues to be effective in people with Parkinson’s disease 15 years after the device is implanted, according to a study published in the June 2, 2021, online issue of Neurology® , the medical journal of…
Novel nano-encapsulation approach for efficient dopamine delivery in Parkinson’s treatment
Parkinson’s disease (PD) is a common neurodegenerative disorder caused by the death of dopaminergic neurons in a part of the brain (known as substantia nigra pars compacta), which leads to a deficit of dopamine (DA), one of the main neurotransmitters…
Modulating rapamycin target protein promotes autophagy, lowering toxic Huntingtin protein
Experiments with small molecule have implications for research on aging.
New algorithm could help enable next-generation deep brain stimulation devices
PROVIDENCE, R.I. [Brown University] — By delivering small electrical pulses directly to the brain, deep brain stimulation (DBS) can ease tremors associated with Parkinson’s disease or help relieve chronic pain. The technique works well for many patients, but researchers would…
Role of sleep-related brain activity in clearing toxic proteins and preventing Alzheimer’s disease
Global brain activity seen on fMRI, and its connection with cerebrospinal fluid flow weaker in brains of individuals with Alzheimer’s disease risk or related toxin buildup
Changes in how cholesterol breaks down in the body may accelerate progression of dementia
Study suggests that some cholesterol medications may impact signaling pathways in the brain, particularly in men
Discovery may point to Parkinson’s disease therapies
University of Guelph researchers have discovered a key way Parkinson’s disease spreads in the brain