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UrduThe goal of a vaccine is to trigger a response that safely protects against an infection and/or the burden of disease. While this is true for all vaccines, the steps leading to a safe and effective product can be different…
Tag: LIVER
The challenges of developing a safe and effective COVID-19 vaccine
The goal of a vaccine is to trigger a response that safely protects against an infection and/or the burden of disease. While this is true for all vaccines, the steps leading to a safe and effective product can be different…
Malaria vaccine: Could this ‘ingredient’ be the secret to success?
Melbourne researchers have identified a microscopic ‘ingredient’ that can be added to a malaria vaccine for efficient protection against the deadly pathogen
Researchers develop new drugs for treating polycystic hepatorena
The project was carried out by UPV/EHU, Biodonostia and Ikerbasque
BioIVT introduces high-purity Kupffer cells to support drug discovery and development for liver diseases and help predict adverse drug reactions
Dysregulation of the Kupffer cell response contributes to liver diseases such as nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH), and liver fibrosis
BioIVT introduces high-purity Kupffer cells to support drug discovery and development for liver diseases and help predict adverse drug reactions
Dysregulation of the Kupffer cell response contributes to liver diseases such as nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH), and liver fibrosis
Steep decline in organ transplants amid COVID-19 outbreak
New analysis shows significant reduction in the number of deceased donor transplants performed in France and the United States
Researchers develop new drugs for treating polycystic hepatorena
The project was carried out by UPV/EHU, Biodonostia and Ikerbasque
Steep decline in organ transplants amid COVID-19 outbreak
New analysis shows significant reduction in the number of deceased donor transplants performed in France and the United States
Xenobiotic Receptor Activation, CRISPR/Cas9, Magnetic Resonance-Guided Radiotherapy, and More Featured in May 2020 Toxicological Sciences
During these difficult times, the Society of Toxicology’s official journal, Toxicological Sciences, remains a source for leading research in toxicology, including in the areas of biomarkers, carcinogenesis, and organ-specific toxicology.
Management of inflammatory bowel diseases: Clinical perspectives
Special issue of Clinical Gastroenterology and Hepatology highlights major advances in inflammatory bowel diseases (IBD) treatment
Management of inflammatory bowel diseases: Clinical perspectives
Special issue of Clinical Gastroenterology and Hepatology highlights major advances in inflammatory bowel diseases (IBD) treatment
New COVID-19 guidance for gastroenterologists
AGA has published new evidence-based recommendations citing that GI symptoms are not as common in COVID-19 as previously estimated
New COVID-19 guidance for gastroenterologists
AGA has published new evidence-based recommendations citing that GI symptoms are not as common in COVID-19 as previously estimated
Study finds highly elevated levels of fatty liver disease for 9/11 first responders
Toxins released at 2001 World Trade Center disaster linked to doubling incidence
Study finds highly elevated levels of fatty liver disease for 9/11 first responders
Toxins released at 2001 World Trade Center disaster linked to doubling incidence
TGF-β-driven reduction of CYGB is associated with oxidative DNA damage of HSCs in NASH
In the 2020 April 21 issue of Journal of Hepatology , a research group from the Department of Hepatology in Osaka City University Graduate School of Medicine, Japan reported that a new insight into the pathophysiology of human nonalcoholic steatohepatitis…
Aspirin linked to reduction in risk of several cancers of the digestive tract
Aspirin is associated with a reduction in the risk of developing several cancers of the digestive tract, including some that are almost invariably fatal, such as pancreatic and liver cancers. The largest and most comprehensive analysis to date of the…
New study indicates exercise can help prevent liver cancer
Exercise retards development of liver cancer by direct effects independent of weight control in an animal model that closely resembles humans with fatty liver disease, report scientists in the Journal of Hepatology
AGA releases official guidance for patients with IBD during the COVID-19 pandemic
Many patients with IBD who develop COVID-19 should stop their medication
UC San Diego to Advance Stem Cell Therapies in New Space Station Lab
UC San Diego and Space Tango received a NASA award to develop the first dedicated stem cell research laboratory within the International Space Station.
Differences by race/ethnicity in stage at diagnosis, treatment, survival for cancers
What The Study Did: Data for 950,000 black, white, Asian and Hispanic patients in the U.S. diagnosed with prostate, ovarian, breast, stomach, pancreatic, lung, liver, esophageal, or colorectal cancers were analyzed to examine differences by race and ethnicity in stage…
Potential early biomarker to track development of non-alcoholic fatty liver disease
BOSTON – (April 6, 2020) – Fatty liver disease not associated with alcohol consumption, which is called Nonalcoholic Fatty Liver Disease or NAFLD, affects more than one billion people worldwide. Even in children the numbers are overwhelming, with up to…
Advanced liver disease patients and transplant recipients need specific care during COVID-19
EASL and ESCMID have issued a Position Paper, providing recommendations for clinicians caring for patients with liver diseases during the current pandemic
New 3D cultured cells mimic the progress of NASH
A research team led by scientists from Tokyo University of Agriculture and Technology (TUAT), Japan, has successfully established 3D cultured tissue that mimics liver fibrosis, a key characteristic of non-alcoholic steatohepatitis (NASH). For making the 3D culture, cells were collected…
AGA issues formal recommendations for PPE during gastrointestinal procedures
PPE during endoscopy should include N95 masks and double gloves
Rivaroxaban superior to heparin in preventing blood clots after common orthopedic surgeries
DOAC more effective in lowering risk of post-procedure VTE without increasing bleeding risk
Study uncovers increasing global rates of liver cancer
New research reveals rising rates of liver cancer around the world, despite advances aimed at preventing the disease. The findings are published early online in CANCER , a peer-reviewed journal of the American Cancer Society (ACS). To obtain trends and…
How Gene Therapy May Hold Key to Treating Life-Threatening Cardiac Disease
New study finds gene therapy improved cardiac, muscle and liver function in Danon disease mouse models.
Using ‘organs-on-a-chip’ to model complicated diseases
A new approach reveals how different tissues contribute to inflammatory diseases such as ulcerative colitis.
How gene therapy may hold key to treating life-threatening cardiac disease
Study finds gene therapy improved cardiac, muscle and liver function in Danon disease mouse models
How intermittent fasting changes liver enzymes and helps prevent disease
Research on mice reveals surprising impact on fat metabolism
Levels of sBTLA proteins as potential marker of overall survival of liver cancer patients
In the 2020 February 25 issue of Scientific Reports , a research group from the Department of Hepatology in Osaka City University Graduate School of Medicine, Japan reported that levels of a circulating soluble immune checkpoint protein can be used…
Levels of sBTLA proteins as potential marker of overall survival of liver cancer patients
In the 2020 February 25 issue of Scientific Reports , a research group from the Department of Hepatology in Osaka City University Graduate School of Medicine, Japan reported that levels of a circulating soluble immune checkpoint protein can be used…
Closing in on liver fibrosis: Detailing the fibrosis process at unprecedented resolution
A new technology to investigate the cellular processes as they change during fibrosis development
Princeton researchers identify factors essential for chronic hepatitis B infection
Virus uses these factors to establish itself permanently in the liver
Liver fibrosis tied to specific heart failure, regardless of HIV or hepatitis C status
(Boston)– While there is an association between liver fibrosis and heart failure, the mechanisms for this association are currently unclear but may be of particular importance for people living with human immunodeficiency virus (HIV) and/or hepatitis C, both of which…
GI symptoms and potential fecal transmission in coronavirus patients
Gastroenterology publishes two studies describing gastrointestinal manifestations and potential for fecal-oral transmission
GI symptoms and potential fecal transmission in coronavirus patients
Gastroenterology publishes two studies describing gastrointestinal manifestations and potential for fecal-oral transmission
Study reveals improving survival rates after liver transplantation in the UK
In the past two decades, death rates after liver transplantation have dropped by more than half in the UK, according to a recent analysis of almost 10,000 liver transplant recipients published in BJS (British Journal of Surgery) . During this…
Study reveals improving survival rates after liver transplantation in the UK
In the past two decades, death rates after liver transplantation have dropped by more than half in the UK, according to a recent analysis of almost 10,000 liver transplant recipients published in BJS (British Journal of Surgery) . During this…
A novel cause of fatty liver in lean people
Published in Annals of Internal Medicine
Adding travel history to patient evaluation could help to prevent spread of coronavirus
1. Adding travel history to patient evaluation could help to prevent spread of coronavirus Abstract: http://annals. org/ aim/ article/ doi/ 10. 7326/ M20-0643 URL goes live when the embargo lifts A commentary published in Annals of Internal Medicine recommends adding…
Adding travel history to patient evaluation could help to prevent spread of coronavirus
1. Adding travel history to patient evaluation could help to prevent spread of coronavirus Abstract: http://annals. org/ aim/ article/ doi/ 10. 7326/ M20-0643 URL goes live when the embargo lifts A commentary published in Annals of Internal Medicine recommends adding…
USPSTF recommendation expands screening for hepatitis C
Bottom Line: The U.S. Preventive Services Task Force (USPSTF) now recommends that adults ages 18 to 79 be screened for hepatitis C virus (HCV) infection. The USPSTF routinely makes recommendations about the effectiveness of preventive care services and this statement updates its…
USPSTF recommendation expands screening for hepatitis C
Bottom Line: The U.S. Preventive Services Task Force (USPSTF) now recommends that adults ages 18 to 79 be screened for hepatitis C virus (HCV) infection. The USPSTF routinely makes recommendations about the effectiveness of preventive care services and this statement updates its…
OHSU-led evidence review shows new therapy for Hepatitis C is highly effective
Review informs new recommendation for universal screening
OHSU-led evidence review shows new therapy for Hepatitis C is highly effective
Review informs new recommendation for universal screening
Discovering what makes durian stink
First evidence of rare amino acid in plants
Even damaged livers can handle life-saving medication
Patients with drug-induced liver damaged may still be able to safely take medications for chronic conditions