A comparison of normal and germ-free mice revealed that as much as 70 percent of a mouse’s gut chemistry is determined by its gut microbiome. Even in distant organs, such as the uterus or the brain, approximately 20 percent of molecules were different in the mice with gut microbes.
Tag: LIVER
New bile discovery will rewrite textbooks
Forget what you know about bile because that’s about to change, thanks to a new discovery made by Michigan State University and published in the current issue of Nature. Much of our knowledge about bile hasn’t changed in many decades. It’s produced in the liver, stored in our gall bladder and injected into our intestine when we eat, where it breaks down fats in our gut.
Possible new treatment strategy for fatty liver disease
Researchers at Karolinska Institutet in Sweden have identified a molecular pathway that when silenced could restore the normal function of immune cells in people with fatty liver disease. The findings could lead to new strategies for treating the condition, which…
How resident microbes restructure body chemistry
As much as 70% of the molecules in a mouse are determined by the microbes that live within the animal
Possible new treatment strategy for fatty liver disease
Researchers at Karolinska Institutet in Sweden have identified a molecular pathway that when silenced could restore the normal function of immune cells in people with fatty liver disease. The findings could lead to new strategies for treating the condition, which…
How resident microbes restructure body chemistry
As much as 70% of the molecules in a mouse are determined by the microbes that live within the animal
Intervention to help GPs identify and treat patients with hepatitis C found to be effective
The first UK clinical trial to increase the identification and treatment of hepatitis C (HCV) patients in primary care has been found to be effective, acceptable to staff and highly cost-effective for the NHS. The University of Bristol-led Hepatitis C…
New tool aids patients in selecting a transplant center
Minneapolis, Minn. – February 24, 2020 – A new website developed by researchers at Hennepin Healthcare Research Institute (HHRI) and the University of Minnesota (UMN) is making it easier for organ transplant candidates to choose which transplant center is right…
New tool aids patients in selecting a transplant center
Minneapolis, Minn. – February 24, 2020 – A new website developed by researchers at Hennepin Healthcare Research Institute (HHRI) and the University of Minnesota (UMN) is making it easier for organ transplant candidates to choose which transplant center is right…
AGA announces new journal Techniques and Innovations in Gastrointestinal Endoscopy
The newest addition to the AGA journal family will focus on advances in endoscopic procedures
AGA announces new journal Techniques and Innovations in Gastrointestinal Endoscopy
The newest addition to the AGA journal family will focus on advances in endoscopic procedures
Gene therapy/gene editing combo could offer hope for some genetic disorders
Novel approach successfully treated experimental model of rare genetic condition
Researchers find test to ID children at higher risk for cystic fibrosis liver disease
AURORA, Colo. (Feb. 12, 2020) – A major multi-center investigation of children with cystic fibrosis has identified a test that allows earlier identification of those at risk for cystic fibrosis liver disease. The study, which includes 11 clinical sites in…
Gene therapy/gene editing combo could offer hope for some genetic disorders
Novel approach successfully treated experimental model of rare genetic condition
Researchers find test to ID children at higher risk for cystic fibrosis liver disease
AURORA, Colo. (Feb. 12, 2020) – A major multi-center investigation of children with cystic fibrosis has identified a test that allows earlier identification of those at risk for cystic fibrosis liver disease. The study, which includes 11 clinical sites in…
Eternygen presents data demonstrating INDY inhibition as novel therapeutic option in NASH
Berlin, Germany, 10 February 2020: Eternygen GmbH, a privately owned, Berlin-based metabolic diseases company, today announced that it is presenting a poster at the 3rd Global NASH Congress held in London, UK from February 10 – 11, 2020 (ElAgroudy et…
Eternygen presents data demonstrating INDY inhibition as novel therapeutic option in NASH
Berlin, Germany, 10 February 2020: Eternygen GmbH, a privately owned, Berlin-based metabolic diseases company, today announced that it is presenting a poster at the 3rd Global NASH Congress held in London, UK from February 10 – 11, 2020 (ElAgroudy et…
Study: Two Enzymes Control Liver Damage in NASH
After identifying a molecular pathway that allows nonalcoholic steatohepatitis (NASH) to progress into liver cell death, University of California San Diego School of Medicine researchers were able to use these pathways to halt further liver damage.
Natural compound in vegetables helps fight fatty liver disease
New research shows how indole can reduce inflammation, fatty deposits
Natural compound in vegetables helps fight fatty liver disease
New research shows how indole can reduce inflammation, fatty deposits
Choosing common pain relievers: It’s complicated
Researchers examine benefits and risks of nonsteroidal anti-inflammatory drugs
Bad to the bone: Specific gut bacterium impairs normal skeletal growth and maturation
Segmented filamentous bacteria, a specific bacterium within the healthy gut microbiome, significantly influences the immune system to impair bone mass accrual during post-pubertal skeletal development
Bad to the bone: Specific gut bacterium impairs normal skeletal growth and maturation
Segmented filamentous bacteria, a specific bacterium within the healthy gut microbiome, significantly influences the immune system to impair bone mass accrual during post-pubertal skeletal development
Human longevity largest study of its kind shows early detection of disease & disease risks
Study published in the journal Proceedings of the National Academy of Sciences
Human longevity largest study of its kind shows early detection of disease & disease risks
Study published in the journal Proceedings of the National Academy of Sciences
Liver Fibrosis “Off Switch” Discovered in Mice
UC San Diego School of Medicine researchers identified several genetic switches, or transcription factors, that determine whether or not liver cells produce collagen — providing a new therapeutic target for liver fibrosis.
Certain liver cells may help prevent organ rejection after transplant, study finds
ROCHESTER, Minn. — Mesenchymal stromal cells from fat tissue and bone marrow are widely used in therapeutic trials for their anti-inflammatory qualities, but new Mayo Clinic research finds that liver cells may be of greater value. The study, published in…
Certain liver cells may help prevent organ rejection after transplant, study finds
ROCHESTER, Minn. — Mesenchymal stromal cells from fat tissue and bone marrow are widely used in therapeutic trials for their anti-inflammatory qualities, but new Mayo Clinic research finds that liver cells may be of greater value. The study, published in…
Certain liver cells may help prevent organ rejection after transplant and other conditions, study finds
Mesenchymal stromal cells from fat tissue and bone marrow are widely used in therapeutic trials for their anti-inflammatory qualities, but new Mayo Clinic research finds that liver cells may be of greater value.
The study, published in Liver Transplantation, finds that liver mesenchymal stromal cells have immunoregulatory qualities that make them more effective than similar cells derived from adipose, or fat, tissue and bone marrow.
Magnetic nanomaterials become an effective treatment against liver fibrosis
A team of scientists from Immanuel Kant Baltic Federal University together with their colleagues from NUST MISiS and RWTH Aachen University (Germany) compared different treatments against liver fibrosis
Obesity crisis blamed for a rise in fatty liver disease amongst young adults
One in five young people have fatty liver disease (steatosis), with one in 40 having already developed liver scarring (fibrosis), research published today [15 January] has found. The study, published in The Lancet Gastroenterology & Hepatology , is the first…
Overspill of fat shown to cause Type 2 Diabetes
For the first time, scientists have been able to observe people developing Type 2 diabetes – and confirmed that fat over-spills from the liver into the pancreas, triggering the chronic condition. The research, led by Professor Roy Taylor at Newcastle…
UTHealth’s Cynthia Ju awarded NIH grants for liver injury research
Tiny solutions are being sought for big liver problems by a scientist at McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth). Armed with two grants totaling $3.6 million from the National Institutes of Health…
Overspill of fat shown to cause Type 2 Diabetes
For the first time, scientists have been able to observe people developing Type 2 diabetes – and confirmed that fat over-spills from the liver into the pancreas, triggering the chronic condition. The research, led by Professor Roy Taylor at Newcastle…
UTHealth’s Cynthia Ju awarded NIH grants for liver injury research
Tiny solutions are being sought for big liver problems by a scientist at McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth). Armed with two grants totaling $3.6 million from the National Institutes of Health…
Researchers create functional mini-liver by 3D bioprinting
Technique developed at Human Genome and Stem Cell Research Center, funded by FAPESP and hosted by the University of São Paulo, produced hepatic tissue in the laboratory in only 90 days and could become an alternative to organ transplantation in future
Researchers create functional mini-liver by 3D bioprinting
Technique developed at Human Genome and Stem Cell Research Center, funded by FAPESP and hosted by the University of São Paulo, produced hepatic tissue in the laboratory in only 90 days and could become an alternative to organ transplantation in future
Math equation predicts and detects liver cancer
UC San Diego researchers pinpoint moment when healthy liver cells become cancerous
Math equation predicts and detects liver cancer
UC San Diego researchers pinpoint moment when healthy liver cells become cancerous
Perinatal exposure to flame retardant alters epigenome, predisposing metabolic disease
UMass Amherst scientist expanding chemical exposure research to include humans
Perinatal exposure to flame retardant alters epigenome, predisposing metabolic disease
UMass Amherst scientist expanding chemical exposure research to include humans
Diet, not exercise, may be key to addressing our biggest cause of liver disease
Edith Cowan University researchers have found that a chronic disease affecting up to 80 per cent of overweight people may be causing an iron deficiency that simply leaves them too tired to get off the couch. Fatty liver disease affects…
Lactobacillus balances gut microbiome and improves chronic-alcohol-induced liver injury
New Rochelle, NY, December 9, 2019–Researchers demonstrated that Lactobacillus rhamnosus can dose-dependently reestablish a balanced intestinal microbiome and counter the liver-damaging effects of alcohol consumption in mice to reverse the results of chronic alcohol-induced liver injury. The design, results, and…
Lactobacillus balances gut microbiome and improves chronic-alcohol-induced liver injury
New Rochelle, NY, December 9, 2019–Researchers demonstrated that Lactobacillus rhamnosus can dose-dependently reestablish a balanced intestinal microbiome and counter the liver-damaging effects of alcohol consumption in mice to reverse the results of chronic alcohol-induced liver injury. The design, results, and…
The next step in organ transplants: New startup takes aim at reperfusion injury
Charleston, SC-based Lydex Pharmaceuticals has received a small business technology transfer grant from the NIH to investigate and develop compounds targeting key enzymes responsible for organ damage, inflammation and rejection after transplant
Anti-hepatitis medicine surprises
A new effective treatment of hepatitis C not only combats the virus, but is also effective against potentially fatal complications such as reduced liver functioning and cirrhosis. This is the result of a new study from Aarhus University.
Anti-hepatitis medicine surprises
A new effective treatment of hepatitis C not only combats the virus, but is also effective against potentially fatal complications such as reduced liver functioning and cirrhosis. This is the result of a new study from Aarhus University.
Firearms, by far, the most lethal method for suicide
Embargoed news from Annals of Internal Medicine
Firearms, by far, the most lethal method for suicide
Embargoed news from Annals of Internal Medicine
Percentage of African ancestry affects gene expression
First study to compare gene production between African Americans