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UrduResults from a retrospective cohort study looks at transfusions before and after Sweden introduced screening of blood in the early 1990s
Tag: LIVER
C-Path’s PSTC, D-RSC receive positive FDA response to plan for liver safety biomarker
Biomarker aims to provide an additional tool for detecting the onset of hepatic injury in clinical trials involving patients with inherited muscle disorders.
Tiny mineral particles are better vehicles for promising gene therapy
University of Wisconsin–Madison researchers have developed a safer and more efficient way to deliver a promising new method for treating cancer and liver disorders and for vaccination — including a COVID-19 vaccine from Moderna Therapeutics that has advanced to clinical trials with humans.
Universal Gut Microbiome-Derived Signature Predicts Cirrhosis
UC San Diego School of Medicine researchers report that stool microbiomes of NAFLD patients are distinct enough to potentially be used to accurately predict which persons with NAFLD are at greatest risk for having cirrhosis.
The Gut Shields the Liver from Fructose-Induced Damage
After one consumes food or a beverage containing fructose, the gut helps to shield the liver from damage by breaking down the sugar. However, the consumption of too much fructose can overwhelm the gut, causing fructose to “spill over” into the liver, where it wreaks havoc and causes fatty liver, researchers discovered.
Maternal obesity increases the chance of liver cancer in offspring for generations
Scientists have identified a microRNA in obese mouse mothers that may increase the odds of liver cancer in their offspring throughout multiple generations, report scientists in the Journal of Hepatology
Maternal obesity increases the chance of liver cancer in offspring for generations
Scientists have identified a microRNA in obese mouse mothers that may increase the odds of liver cancer in their offspring throughout multiple generations, report scientists in the Journal of Hepatology
Liver perfusion could save 7 in 10 rejected donor livers
A major study investigating the effectiveness of liver perfusion as a technique to improve the function of donor livers that would have otherwise been rejected has shown that up to 7 in every 10 could be used after just 4-6 hours of the assessment.
Novotech webinar: Why Asia-Pacific attracts 60% of all hepatology trials globally
This webinar focusses on the reasons why the Asia-Pacific is attracting 60% of ongoing and planned hepatology trials globally (source GlobalData).
Novotech webinar: Why Asia-Pacific attracts 60% of all hepatology trials globally
This webinar focusses on the reasons why the Asia-Pacific is attracting 60% of ongoing and planned hepatology trials globally (source GlobalData).
International NASH Day declares urgency to combat epidemics of liver disease and COVID
Obesity, type II diabetes, and high blood pressure increase the risk of NASH and negatively affect outcomes for COVID-19 patients
NIH scientists develop blood test to help improve liver cancer screening
Scientists have developed a new test that can help identify people who are likely to develop hepatocellular carcinoma (HCC), the most common form of liver cancer. The approach uses a simple blood test to check for the patient’s previous exposure…
NIH scientists develop blood test to help improve liver cancer screening
Scientists have developed a new test that can help identify people who are likely to develop hepatocellular carcinoma (HCC), the most common form of liver cancer. The approach uses a simple blood test to check for the patient’s previous exposure…
Link between liver and heart disease could lead to new therapeutics
A newly published study of flies found that protecting liver function also preserves heart health. The research could lead to new therapeutic approaches in human health and illuminate the role of understudied organelles known as peroxisomes.
Fecal transplants show promise as treatment for non-alcoholic fatty liver disease
LONDON, ON – A new study from Lawson Health Research Institute and Western University suggests that fecal transplants could be used as a treatment for non-alcoholic fatty liver disease (NAFLD). The randomized controlled trial published in the American Journal of…
AGA does not recommend the use of probiotics for most digestive conditions
New AGA guideline finds that evidence to support use of probiotics to treat digestive diseases is greatly lacking, identifying only three clinical scenarios where probiotics may benefit patients
NAFLD in pregnancy increases risks for mother and baby
Women with non-alcoholic fatty liver disease (NAFLD) should receive preconception counseling about increased maternal and infant risks, while pregnant mothers may benefit from evaluation by a high-risk obstetrics team, recommend scientists
Fecal transplants show promise as treatment for non-alcoholic fatty liver disease
LONDON, ON – A new study from Lawson Health Research Institute and Western University suggests that fecal transplants could be used as a treatment for non-alcoholic fatty liver disease (NAFLD). The randomized controlled trial published in the American Journal of…
AGA does not recommend the use of probiotics for most digestive conditions
New AGA guideline finds that evidence to support use of probiotics to treat digestive diseases is greatly lacking, identifying only three clinical scenarios where probiotics may benefit patients
NAFLD in pregnancy increases risks for mother and baby
Women with non-alcoholic fatty liver disease (NAFLD) should receive preconception counseling about increased maternal and infant risks, while pregnant mothers may benefit from evaluation by a high-risk obstetrics team, recommend scientists
With $16.5 million in NIH funding, MUSC opens two new digestive disease research centers
The recent openings of two centers have put the Medical University of South Carolina on the map as a leading institution for digestive and liver disease research.
New clues on how lipid emulsions prevent liver disease in preterm babies
Infants born prematurely may require parenteral or intravenous nutrition to provide the necessary nourishment, as their digestive system is immature and cannot digest nutrients. However, prolonged parenteral nutrition is associated with complications, including cholestasis, or lack of bile flow from…
Uncuffing nitric oxide production: Beta-arrestin2 complexes regulate NO levels
Beta-arrestin2 is a critical protein that regulates the activity of endothelial nitric oxide synthase and the subsequent production of nitric oxide; however, following liver damage, beta-arrestin2 levels are reduced and this pathway is dysregulated
Women are not more likely to die of cirrhosis than men, despite fewer liver transplants
First study to show women don’t have higher mortality from cirrhosis
New clues on how lipid emulsions prevent liver disease in preterm babies
Infants born prematurely may require parenteral or intravenous nutrition to provide the necessary nourishment, as their digestive system is immature and cannot digest nutrients. However, prolonged parenteral nutrition is associated with complications, including cholestasis, or lack of bile flow from…
Uncuffing nitric oxide production: Beta-arrestin2 complexes regulate NO levels
Beta-arrestin2 is a critical protein that regulates the activity of endothelial nitric oxide synthase and the subsequent production of nitric oxide; however, following liver damage, beta-arrestin2 levels are reduced and this pathway is dysregulated
Women are not more likely to die of cirrhosis than men, despite fewer liver transplants
First study to show women don’t have higher mortality from cirrhosis
Mass general model projects sharp rise in alcohol-related liver disease
Alcohol-related liver disease is currently the most common reason for liver transplantation in the United States. In recent years, high-risk drinking of alcohol–defined as exceeding daily drinking limits (more than 4 or 5 standard drinks for women and men, respectively)…
Lab-Grown Miniature Human Livers Successfully Transplanted in Rats
Using skin cells from human volunteers, researchers at the University of Pittsburgh School of Medicine have created fully functional mini livers, which they then transplanted into rats. In this proof-of-concept experiment, the lab-made organs survived for four days inside their animal hosts.
Modified Parkinson’s drug shows potential in treating nonalcoholic fatty liver disease
Scientists spur advances in fatty liver disease therapy by modifying an existing neurological drug
Modified Parkinson’s drug shows potential in treating nonalcoholic fatty liver disease
Scientists spur advances in fatty liver disease therapy by modifying an existing neurological drug
The AGA Research Foundation provides over $2 million in funding to promising researchers
The AGA Research Foundation funded 17 awards in the 2020 awards cycle
The AGA Research Foundation provides over $2 million in funding to promising researchers
The AGA Research Foundation funded 17 awards in the 2020 awards cycle
New model shows how cells that cause liver cancer are created
Scientists show in-vivo and in-vitro how liver cancer stem cells are born, solving a central scientific mystery in this field
New model shows how cells that cause liver cancer are created
Scientists show in-vivo and in-vitro how liver cancer stem cells are born, solving a central scientific mystery in this field
Factors associated with sex-based disparities in liver transplants
What The Study Did: This observational study looked at the disparities that exist between women and men waiting to receive a liver transplant, such as being more likely to die while on the wait list, and how much these differences…
Ketogenic diets alter gut microbiome in humans, mice
Study suggests potential anti-inflammatory properties of ketone bodies via effects on gut microbial ecosystems
Factors associated with sex-based disparities in liver transplants
What The Study Did: This observational study looked at the disparities that exist between women and men waiting to receive a liver transplant, such as being more likely to die while on the wait list, and how much these differences…
Ketogenic diets alter gut microbiome in humans, mice
Study suggests potential anti-inflammatory properties of ketone bodies via effects on gut microbial ecosystems
Chemicals often found in consumer products could lead to obesity and fatty liver diseases
While poor nutrition and lack of exercise contribute to obesity, exposure to these compounds could trigger lifelong susceptibility to weight gain, Baylor University researcher says
Additional genetic cause for non-alcoholic fatty liver disease discovered
In Germany about 18 million people suffer from non-alcoholic fatty liver. The causes of this disease are manifold and include environmental as well as genetic factors. DZD researchers have now discovered new genes that play a role in the development…
Navigating nonalcoholic fatty liver disease (NAFLD)
Special issue of Gastroenterology serves as clinician’s roadmap to the rapidly changing developments in NAFLD treatment
Researchers find potential drug treatment targets for alcohol-related liver disease
Alcohol-related liver disease (ALD) is a deadly condition affecting more than 150 million people worldwide with no treatment available besides transplant. But now, a team led by researchers from Massachusetts General Hospital (MGH) has uncovered key molecular step stones in…
Chemicals often found in consumer products could lead to obesity and fatty liver diseases
While poor nutrition and lack of exercise contribute to obesity, exposure to these compounds could trigger lifelong susceptibility to weight gain, Baylor University researcher says
Additional genetic cause for non-alcoholic fatty liver disease discovered
In Germany about 18 million people suffer from non-alcoholic fatty liver. The causes of this disease are manifold and include environmental as well as genetic factors. DZD researchers have now discovered new genes that play a role in the development…
Navigating nonalcoholic fatty liver disease (NAFLD)
Special issue of Gastroenterology serves as clinician’s roadmap to the rapidly changing developments in NAFLD treatment
Researchers find potential drug treatment targets for alcohol-related liver disease
Alcohol-related liver disease (ALD) is a deadly condition affecting more than 150 million people worldwide with no treatment available besides transplant. But now, a team led by researchers from Massachusetts General Hospital (MGH) has uncovered key molecular step stones in…
Liver cancer: Awareness of hepatitis D must be raised
Of all the hepatitis viruses, D is the most poorly known. This small virus, which can only infect people already infected with Hepatitis B, has so far been little studied. Hepatitis D is one of the most dangerous forms of chronic viral…
Liver cancer: Awareness of hepatitis D must be raised
Of all the hepatitis viruses, D is the most poorly known. This small virus, which can only infect people already infected with Hepatitis B, has so far been little studied. Hepatitis D is one of the most dangerous forms of chronic viral…
COVID-19 triggers innovative healthcare collaboration, yet liver care suffers setbacks
International experts describe a rise in innovative, cooperative mitigating approaches during the pandemic, but note that essential hepatitis and other liver-related services are suffering impediments and delays