Clinical and pre-clinical antimicrobial drug development

This book series brings updated reviews to readers interested in advances in the development of anti-infective drug design and discovery. It covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry,…

Foresight diagnostics to show vision of the new standard of lymphoma MRD detection at ICML

AURORA, COLORADO, June 16, 2021 — Foresight Diagnostics, the emerging leader in blood-based lymphoma disease monitoring, announced today that clinical performance of its minimal residual disease (MRD) detection platform in diffuse large B-cell lymphoma (DLBCL) will be presented at the…

New research finds ways to improve accuracy of Lateral Flow Tests

Research published in the journal ACS Materials and Interfaces has provided new understanding of how false-negative results in Lateral Flow Tests occur and provides opportunity for simple improvements to be made. Lateral Flow Devices were introduced late in 2020 on…

New treatment stops progression of Alzheimer’s disease in monkey brains

A new therapy prompts immune defense cells to swallow misshapen proteins, amyloid beta plaques and tau tangles, whose buildup is known to kill nearby brain cells as part of Alzheimer’s disease, a new study shows. Led by researchers at NYU…

Speech droplets drive transmission of SARS-CoV-2

A new review published in the Journal of Internal Medicine indicates that unmasked speech in confined spaces poses the greatest risk of spreading SARS-CoV-2, the virus that causes COVID-19, to others. The focus of the review is on the interface…

A new culprit in antibacterial resistance: cysteine persulfide

A joint research project based in Kumamoto University , Japan has developed a new, highly sensitive analytical method that can detect degraded β-lactam antibacterial agents used in the treatment of bacterial infections. With this method, researchers found that reactive sulfur…

Social media use one of four factors related to higher COVID-19 spread rates early on

TORONTO, June 9, 2021 – Researchers from York University and the University of British Columbia have found social media use to be one of the factors related to the spread of COVID-19 within dozens of countries during the early stages…

Researcher gets $2.7 million grant to study seasonal and universal vaccination in aged populations

ATLANTA–Dr. Sang-Moo Kang, professor in the Institute for Biomedical Sciences at Georgia State University, has received a five-year, $2.7 million federal grant to study seasonal and universal vaccination in elderly populations with pre-existing immunity to influenza viruses. The grant from…

Secondary infections inflame the brain, worsening cognition in Alzheimer’s disease

New research into Alzheimer’s disease (AD) suggests that secondary infections and new inflammatory events amplify the brain’s immune response and affect memory in mice and in humans – even when these secondary events occur outside the brain. Scientists believe that…

Alzheimer’s disease raises the risk of severe COVID-19 and death from this viral disease

Patients with dementia and especially Alzheimer’s run a threefold risk of dying as a result of infection by SARS-CoV-2. The risk is six times greater if they are over 80, according to a study by Brazilian researchers

Luring bacteria into a trap

Developing vaccines against bacteria is in many cases much more difficult than vaccines against viruses. Like virtually all pathogens, bacteria are able to sidestep a vaccine’s effectiveness by modifying their genes. For many pathogens, such genetic adaptations under selective pressure…