New non-invasive method to track the progress of one highly sought-after anti-cancer immunotherapy can change research in the field
Tag: IMMUNOLOGY/ALLERGIES/ASTHMA
Researchers find potential path to a broadly protective COVID-19 vaccine using T cells
Using a method developed for HIV, researchers have identified stable T cell vaccine targets in SARS-CoV-2
Study with healthcare workers supports that immunity to SARS-CoV-2 is long-lasting
Despite a large heterogeneity in Spike-specific antibody levels, most individuals remain seropositive for at least one year after infection
Between fear and confidence
The new issue of the Science Magazine BfR2GO deals with fear
Employed individuals more likely to contract the flu, study shows
A University of Arkansas researcher and international colleagues found that employed individuals, on average, are 35.3% more likely to be infected with the flu virus.
Proteins could offer risk markers and therapy targets in diabetic kidney disease
A 7- to 15-year longitudinal study of 358 diabetics has linked 3 proteins in blood with a slower progression of diabetic kidney disease and progressive kidney failure. The results from Zaipul Md Dom and colleagues suggest that the proteins could…
COVID-19: Reduced sense of taste and smell lingers
Patients with mild Covid-19 infections experience a significantly increased longer lasting reduced sense of taste and smell.
COVID-19: Reduced sense of taste and smell lingers
Patients with mild COVID-19 infections experience a significantly increased longer lasting reduced sense of taste and smell; this is also the case for long-term shortness of breath, although relatively few people are affected
A promising two-punch therapy for Langerhans cell histiocytosis
Langerhans cell histiocytosis (LCH) is a rare cancer involving dendritic cells, a type of white blood cell that usually helps defend against infections. The current standard of care for LCH, chemotherapy, cures fewer than half of patients. “Our research team…
Study finds structural changes in the SARS-CoV-2 Alpha and Beta variants
Changes to the ‘spike’ protein explain Alpha’s faster spread, and how the Beta variant evades immune responses, suggesting the need for a booster with an updated vaccine
Clinical and pre-clinical antimicrobial drug development
This book series brings updated reviews to readers interested in advances in the development of anti-infective drug design and discovery. It covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry,…
Study examines how breast implant surfaces affect immune response
Rice University bioengineers collaborated on a six-year study that systematically analyzed how the surface architecture of breast implants influences the development of adverse effects, including an unusual type of lymphoma.
Foresight diagnostics to show vision of the new standard of lymphoma MRD detection at ICML
AURORA, COLORADO, June 16, 2021 — Foresight Diagnostics, the emerging leader in blood-based lymphoma disease monitoring, announced today that clinical performance of its minimal residual disease (MRD) detection platform in diffuse large B-cell lymphoma (DLBCL) will be presented at the…
Study reveals recipe for even more powerful COVID-19 vaccines
NEIDL, Broad Institute scientists say next-generation vaccines could stimulate another arm of the immune system, imparting better protection against coronavirus variants
Immune system dysfunction can modify the association between cannabis use and psychosis
Brazilian researchers show that a combination of inflammatory cytokines in the blood and cannabis use, daily or during adolescence, heightens the odds of developing psychiatric disorders
$1 million grant to address cold storage logistics in vaccine delivery
COVID-19 vaccines have been tested, validated and administered to millions of people around the world. But in some countries, the vaccines have yet to arrive in great enough numbers. One significant hurdle is that the vaccines must be stored between…
Natural killers: Using the body’s cells to target breast cancer
Study lays groundwork for possible new immunotherapy for the world’s most commonly diagnosed cancer
New research finds ways to improve accuracy of Lateral Flow Tests
Research published in the journal ACS Materials and Interfaces has provided new understanding of how false-negative results in Lateral Flow Tests occur and provides opportunity for simple improvements to be made. Lateral Flow Devices were introduced late in 2020 on…
Idea of COVID-19 ‘immunity passports’ decreases people’s compliance with restrictions
Researchers from the University of Kent’s School of Psychology have found that when people are presented with the idea of a COVID-19 ‘immunity passport,’ they show less willingness to follow social distancing and face covering guidelines
New treatment stops progression of Alzheimer’s disease in monkey brains
A new therapy prompts immune defense cells to swallow misshapen proteins, amyloid beta plaques and tau tangles, whose buildup is known to kill nearby brain cells as part of Alzheimer’s disease, a new study shows. Led by researchers at NYU…
COVID-19 reinfection rate less than 1% for those with severe illness
Two deaths were associated with reinfection, but most cases were mild
Women leaving jail have high vaccine hesitancy; app drops resistance, boosts literacy
Vulnerable population offers keys to better communications on vaccines, researchers argue
Molecular changes in white blood cells can help diagnose ‘the bends’ earlier in divers
First study to show gene expression changes in divers with ‘the bends’ reveals key role of genes for inflammation and immunity
Osteoarthritis linked to higher Parkinson’s disease risk
A study published in Arthritis Care & Research has uncovered an elevated risk of Parkinson’s disease in individuals with osteoarthritis. The retrospective study using Taiwan’s Longitudinal Health Insurance Database 2005 included 33,360 patients who were 50-64 years old and had…
Speech droplets drive transmission of SARS-CoV-2
A new review published in the Journal of Internal Medicine indicates that unmasked speech in confined spaces poses the greatest risk of spreading SARS-CoV-2, the virus that causes COVID-19, to others. The focus of the review is on the interface…
Study confirms safety and effectiveness of COVID-19 vaccination in people with cancer
Since the early days of the COVID-19 pandemic, there were questions about how people in active cancer treatment would fare if they became infected with SARS-CoV-2. The worries were due, in large part, to the effects that cancer and its…
A new culprit in antibacterial resistance: cysteine persulfide
A joint research project based in Kumamoto University , Japan has developed a new, highly sensitive analytical method that can detect degraded β-lactam antibacterial agents used in the treatment of bacterial infections. With this method, researchers found that reactive sulfur…
COVID vaccine linked to low platelet count, nationwide study suggests
A condition that affects the blood, known as idiopathic thrombocytopenic purpura (ITP), may be associated the Oxford-AstraZeneca vaccine in rare cases, research suggests. The very small increased risk of the condition – which is characterised by low platelet counts –…
Free event will connect heart, lung, blood and sleep point-of-care inventors with resources
M2D2 program to feature NIH, Johnson & Johnson leaders
UT extension receives grants for COVID-19 and other vaccine education
USDA, CDC and Cooperative Extension team to support communication nationwide
Social media use one of four factors related to higher COVID-19 spread rates early on
TORONTO, June 9, 2021 – Researchers from York University and the University of British Columbia have found social media use to be one of the factors related to the spread of COVID-19 within dozens of countries during the early stages…
ONK Therapeutics and Trinity researchers seek improved cancer therapies
ONK Therapeutics Ltd, an innovative natural killer (NK) cell therapy company, today announced that it has been awarded an Innovation Partnership Programme (IPP) grant by Enterprise Ireland (EI) to fund collaborative research at Trinity College Dublin, Ireland, led by Dr.…
Vilcek Foundation awards $100,000 prize to Dr. Katalin Karikó for pioneering mRNA research
Dr. Katalin Karikó receives the 2022 Vilcek Prize for Excellence in Biotechnology for her scientific contributions that led to the development of mRNA vaccines for COVID-19
Protein identified as new therapeutic anti-viral target for COVID-19
New research identified a novel interaction between the SARS-CoV-2 spike protein and the galectin-3-binding protein (LGALS3BP) which could be a new therapeutic anti-viral target.
An ‘atlas’ of the brain’s choroid plexus across the lifespan
New resource for neuroscience maps cell types, secreted proteins, spatial organization, and more
Hospitalized individuals with active cancer more likely to die from COVID-19
Patients with blood cancers at greatest risk of COVID-19 death
A new hope: A novel vaccine against COVID-19 is safe and induces antibody production
Early-phase clinical trials show that a vaccine called KCONVAC is safe and stimulates antibody production in Chinese adults
Researchers discover how cowpea mosaic plant virus activates immune system against cancer
Immunology researchers led by Dartmouth and Dartmouth-Hitchcock’s Norris Cotton Cancer Center discover how the cowpea mosaic plant virus is recognized by and strongly stimulates the immune system to attack and often eliminate cancerous tumors
International coalition classifies 25 subtypes of uveitis, an inflammatory eye disease
NIH-funded classification criteria will facilitate clinical research for new therapies
The molecular underpinnings of immune cell migration
Researchers from Osaka University reveal the molecular mechanism by which immune cells migrate and reach the site of infection
Space travel weakens our immune systems: Now scientists may know why
Final study by UCSF astronaut points to Treg cells as the culprit
How do bad kidneys lead to heart disease? Broken cellular clocks provide new clues
Researchers find how chronic kidney disease induces heart inflammation through white blood cells
Researcher gets $2.7 million grant to study seasonal and universal vaccination in aged populations
ATLANTA–Dr. Sang-Moo Kang, professor in the Institute for Biomedical Sciences at Georgia State University, has received a five-year, $2.7 million federal grant to study seasonal and universal vaccination in elderly populations with pre-existing immunity to influenza viruses. The grant from…
Secondary infections inflame the brain, worsening cognition in Alzheimer’s disease
New research into Alzheimer’s disease (AD) suggests that secondary infections and new inflammatory events amplify the brain’s immune response and affect memory in mice and in humans – even when these secondary events occur outside the brain. Scientists believe that…
Alzheimer’s disease raises the risk of severe COVID-19 and death from this viral disease
Patients with dementia and especially Alzheimer’s run a threefold risk of dying as a result of infection by SARS-CoV-2. The risk is six times greater if they are over 80, according to a study by Brazilian researchers
Pfizer-BioNTech vaccine recipients have lower antibody levels targeting the Delta variant
Levels of antibodies in the blood of vaccinated people that are able to recognise and fight the new SARS-CoV-2 Delta variant first discovered in India (B.1.617.2) are on average lower than those against previously circulating variants in the UK, according…
The dream team: Scientists find drug duo that may cure COVID-19 together
Preclinical experiments show that the drugs cepharanthine and nelfinavir may be effective treatments for COVID-19
Studies reveal skull as unexpected source of brain immunity
Immune cells from skull bone marrow guard the brain, spinal cord
Extensive study identifies over a dozen existing drugs as potential COVID-19 therapies
FDA-approved drugs or experimental drugs with ample health data could be rapidly tested in humans for treatment of COVID-19
Luring bacteria into a trap
Developing vaccines against bacteria is in many cases much more difficult than vaccines against viruses. Like virtually all pathogens, bacteria are able to sidestep a vaccine’s effectiveness by modifying their genes. For many pathogens, such genetic adaptations under selective pressure…