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UrduNo Smoking Day 2021
Tag: IMMUNOLOGY/ALLERGIES/ASTHMA
Study evaluates the filtration efficacy of 227 commercially available face masks in Brazil
Models for professional use were the most effective at retaining aerosol particles of a size equivalent to the novel coronavirus, followed by TNT masks sold in drugstores; the efficacy of fabric masks ranged from 15% to 70%
Protein disguise could be new target for cancer immunotherapy
Peer reviewed Experimental study / Meta-analysis Animals / Human data Protein disguise could be new target for cancer immunotherapy Researchers at the Francis Crick Institute have identified a protein that helps tumours evade the immune system and, in certain types…
Immunotherapy after surgery reduces deadly relapse risk in advanced bladder cancer
Clinical trial results point to change in care of patients with high risk of metastatic recurrence
New study may help explain low oxygen levels in COVID-19 patients
U of A researchers find SARS-CoV-2 infects immature red blood cells, reducing oxygen in the blood and impairing immune response
Direct action of SARS-CoV-2 on organs may cause exacerbated immune response in children
Researchers found that SARS-CoV-2 had spread throughout the body via the blood vessels, infecting various types of cell and tissue in these children; the clinical manifestations varied according to the organ targeted
Parasites may accumulate in spleens of asymptomatic individuals infected with malaria
Study suggests immature red blood cells in spleen are targeted for invasion by P. vivax
Time-dependent viral interference between influenza virus and coronavirus in the infection of differ
Time-dependent viral interference between influenza virus and coronavirus in the infection of differentiated porcine airway epithelial cells
Scientists develop novel therapy for crimean-congo hemorrhagic fever virus
Army scientists working as part of an international consortium have developed and tested an antibody-based therapy to treat Crimean-Congo hemorrhagic fever virus (CCHFV), which is carried by ticks and kills up to 60 percent of those infected. Their results are…
Helping doctors manage COVID-19
New tool uses AI technology to assess the severity of lung infections and inform treatment
FAPESP will discuss an integrative approach to clinical long-term effects of COVID-19
Renowned scientists sharing their research and clinical practice will take part at the webinar. They will tackle the patients’ evolving clinical conditions and the challenges of dealing with the subacute phase.
Safe laboratory-made molecules for global vaccination success
Chemists succeed in artificially manufacturing important building blocks for mRNA vaccines
Elucidating how the production of antibodies is regulated, one cell at a time
A study coordinated by Luís Graça, principal investigator at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal) and Professor at the Faculty of Medicine of the University of Lisbon (FMUL) used lymph nodes, tonsils and blood, to show…
Assessment of SARS-CoV-2 reinfection 1 year after primary infection in Lombardy, Italy
What The Study Did: Study r esults suggest that reinfections are rare events and that patients who have recovered from COVID-19 have a lower risk of reinfection. However, the observation ended before SARS-CoV-2 variants began to spread, and it is…
DNA vaccines for COVID-19 effective in mice, hamsters
Currently available COVID-19 vaccines rely on mRNA strands to teach the human immune system to recognize the SARS-CoV-2 virus. Now, researchers reporting in PLOS Neglected Tropical Diseases have reported the successful development of a vaccine that instead uses DNA encoding…
Versatile coronavirus antibody may be starting point for broader-acting vaccines
A special type of antibody is produced in patients who’ve had COVID-19 as well as less-serious coronaviruses that cause colds.
Study shows SARS-CoV-2 variants unlikely to affect T cell responses
In a new study, scientists at The Hong Kong University of Science and Technology (HKUST) have revealed that most T cell epitopes known to be targeted upon natural infection are seemingly unaffected by current SARS-CoV-2 variants.
Older Canadians say they’re more willing to get the flu shot in the wake of COVID-19
The pandemic has increased older adults’ willingness to receive the flu shot, new research shows. The study analyzed survey results of 4,501 Canadians over the age of 50 from ten provinces. Twenty per cent of 1,001 research participants aged 50…
Research uncovers how ‘non-professional’ cells can trigger immune response
Worm cells sense changes in metabolism to activate defensive measures against pathogens
An inhalable nanobody-based treatment prevented and treated SARS-CoV-2 infections in hamsters
Inhalable Nanobody (PiN-21) prevents and treats SARS-CoV-2 infections in Syrian hamsters at ultra-low doses
HKUST’s meta-analysis shows SARS-CoV-2 variants unlikely to affect T cell responses
In a new study, scientists at The Hong Kong University of Science and Technology (HKUST) have revealed that most T cell epitopes known to be targeted upon natural infection are seemingly unaffected by current SARS-CoV-2 variants. In their latest research,…
Ultra-low doses of inhaled nanobodies effective against COVID-19 in hamsters
PITTSBURGH, May 26, 2021 – In a paper published today in Science Advances , researchers from the University of Pittsburgh School of Medicine showed that inhalable nanobodies targeting the spike protein of the SARS-CoV-2 coronavirus can prevent and treat severe…
Immune cells imperfect at distinguishing between friend and foe, study suggests
A new study that upends the idea that T cells can perfectly distinguish between healthy and infected cells may lead to improved approaches to treating cancer and autoimmune diseases.
C-Path Virtual Workshop to feature latest advances in clinical trials for T1D
More than 300 attendees and 20 speakers are expected to participate in the international workshop, June 15-16
A COVID-fighter’s guide to T cells
New LJI review shows how T cells target more than 1,400 sites on SARS-CoV-2
Dengue immune function discovery could benefit much-needed vaccine development
Novel approach could aid new vaccines as global dengue virus infections far surpass COVID-19
Diabetes vaccine gives promising results in a genetic subgroup
A clinical study led by Linköping University and financed by pharmaceuticals company Diamyd Medical has investigated whether immunotherapy against type 1 diabetes can preserve the body’s own production of insulin. The results suggest that injection of a protein, GAD, into…
How hepatitis C virus evades the immune system
Researchers from Osaka University discover a novel molecular mechanism by which hepatitis C virus evades the immune system to cause chronic infection
Face masks effectively limit SARS-CoV-2 transmission
‘Don’t forget the mask’ – although most people nowadays follow this advice, professionals express different opinions about the effectiveness of face masks.
A novel defense mechanism for SARS-CoV-2 discovered
Scientists from Hokkaido University have discovered a novel defensive response to SARS-CoV-2 that involves the viral pattern recognition receptor RIG-I.
A novel defense mechanism for SARS-CoV-2 discovered
Scientists from Hokkaido University have discovered a novel defensive response to SARS-CoV-2 that involves the viral pattern recognition receptor RIG-I. Upregulating expression of this protein could strengthen the immune response in COPD patients. In the 18 months since the first…
In utero exposure to tiny air pollution particles is linked to asthma in preschoolers
Mount Sinai researchers are first to find ultrafine particles from traffic pollution influences asthma risk in US children
Pivotal results from Trinity clinical trial for the chronic condition atopic dermatitis
Trinity College and St James’s Hospital Dublin research offers additional treatment option to patients impacted by the chronic inflammatory skin condition.
Immune genetics and previous common cold infections might help protect Japan from COVID-19
A highly immunogenic HLA-A*24:02-restricted T cell epitope is shared between COVID-19 and common cold coronaviruses
Newly identified antibody can be targeted by HIV vaccines
The previously undescribed antibody points to new vaccine strategies for HIV, COVID
Nearly 3% of Americans take immune-weakening drugs that may limit COVID vaccine response
Many are taking steroids that could increase risk of COVID-related hospitalization, researchers say
Why are some Covid-19 vaccines working better for men than women?
MSU researcher is studying, raising awareness about the role of sex in the efficacy of vaccines that make use of nanomedicine
A brand new cocktail to fight HIV
Montréal, May 20, 2021–Researchers at the University of Montreal Hospital Research Centre (CRCHUM) and Yale University have succeeded in reducing the size of the HIV reservoir in humanized mice by using a “molecular can opener” and a combination of antibodies…
Canadian researchers studying effectiveness, safety of COVID-19 vaccines during pregnancy
Dr. Deshayne Fell of CHEO Research Institute and University of Ottawa leads Ontario portion by studying BORN baby registry and province’s vaccination registry
Novel immunotherapy boosts long-term stroke recovery in mice
PITTSBURGH, May 19, 2021 – Specialized immune cells that accumulate in the brain in the days and weeks after a stroke promote neural functions in mice, pointing to a potential immunotherapy that may boost recovery after the acute injury is…
Rogue antibodies wreak havoc in severe COVID-19 cases
The development of antibodies to the COVID-19 virus has been the great long-term hope of ending the pandemic. However, immune system turncoats are also major culprits in severe cases of COVID-19, Yale scientists report in the journal Nature . These…
Tezepelumab significantly reduced asthma exacerbations: Phase 3 NAVIGATOR trial
ATS 2021, New York, NY – Results from the NAVIGATOR study of tezepelumab showed that the new biologic therapy significantly reduced exacerbations requiring hospital stays and emergency department (ED) visits for adults and adolescents with severe, uncontrolled asthma, according to…
VOYAGE phase 3: Dupilumab significantly reduced asthma exacerbations in children age 6-11
ATS 2021, New York, NY – Results from the VOYAGE study of dupilumab (Dupixent) showed that the monoclonal antibody significantly reduced exacerbations in children ages 6-11 with uncontrolled moderate-to-severe asthma, compared to placebo, according to research presented at the ATS…
Study led by NTU Singapore finds that microbes work as a network in causing lung infection
Traditionally, an infection is thought to happen when microbes – bacteria, fungi, or viruses – enter and multiply in the body, and its severity is associated with how prevalent the microbes are in the body. Now, an international research team…
Triple-drug therapy safely cuts serious asthma flares
Including third drug to commonly used dual-drug inhalers can reduce asthma exacerbations
Better donor evaluation, drug therapy in sight for kidney transplants
AUGUSTA, Ga. (May 18, 2021) – Looking to improve organ transplant success, researchers are working to learn more about how an immune molecule, which also protects a fetus, helps protect some transplanted kidneys, and to develop a synthetic version of…
How x-rays could make reliable, rapid COVID-19 tests a reality
An imaging technique pioneered by Berkeley Lab is helping reveal the best antibodies for COVID-19 detection
Towards a universal flu vaccine for Indigenous populations
Researchers have identified specific influenza targets that could be used to better protect Indigenous people from experiencing severe influenza disease through a universal, T cell-based vaccine. In a collaboration with Monash Biomedicine Discovery Institute, Menzies School of Health Research and…
People who have had dengue are twice as likely to develop symptomatic COVID-19
This is the main finding of a study.The authors analyzed blood samples collected in a town in the Brazilian Amazon before and after the first wave of the pandemic to detect the presence of antibodies against dengue virus and SARS-CoV-2.
Combining immunotherapies against cancer
New combination of vaccine and immune checkpoint inhibitors as a promising approach to improving the success of cancer treatment