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UrduStatins can help lower cholesterol and reduce the risk of heart attacks, stroke and other heart and vascular problems. But they aren’t right for all patients, and they can rarely cause side effects. Cardiologist Melissa Tracy answers patients’ most frequently asked questions about statins.
Tag: Statins
Can Taking Statins After a Bleeding Stroke Lower Risk of Another Stroke?
People who have had a stroke called an intracerebral hemorrhage who take cholesterol-lowering drugs called statins may have a lower risk of having another stroke, especially ischemic stroke, compared to people who also had an intracerebral hemorrhage but were not taking statins, according to a new study published in the August 30, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Statins underused for primary prevention of cardiovascular disease in racial, ethnic minorities and women
An analysis of persons eligible for statin use to prevent atherosclerotic cardiovascular disease (ASCVD) found disparities in the prevalence of statin use for primary or secondary prevention of ASCVD among racial and ethnic minorities and women.
One pill doesn’t fit all: cholesterol study reveals effects on lung function and brain size
The first study in the world to compare cholesterol-lowering medications on a range of diseases has good and bad news for more than 200 million people.
Rutgers Expert Available to Comment on Cholesterol Drug for Statin Intolerant Patients
Emily Aboujaoude, clinical assistant professor at Rutgers University’s Ernest Mario School of Pharmacy, can comment on the NEJM trial finding bempedoic acid (Nexletol) lowers cholesterol in patients who cannot tolerate statins. The following quotes from Aboujaoude are available to journalists…
Cholesterol-lowering Drugs Linked to Lower Risk of Bleeding Stroke
People who take cholesterol-lowering drugs called statins may have a lower risk of having a type of stroke called an intracerebral hemorrhage, according to a new study published in the December 7, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology. An intracerebral hemorrhage is caused by bleeding in the brain.
Vitamin D fails to reduce statin-associated muscle pain
Patients who take statins to lower high cholesterol levels often complain of muscle pains, which can lead them to stop taking the highly effective medication and put them at greater risk of heart attack or stroke.
Deepak L. Bhatt, MD, MPH, Named Director of Mount Sinai Heart
Will also serve as the first-ever Dr. Valentin Fuster Professor of Cardiovascular Medicine
Real-world data links rosuvastatin with signs of kidney damage
Compared with atorvastatin, rosuvastatin was associated with an 8% higher risk of hematuria (blood in the urine), a 17% higher risk of proteinuria (protein in the urine), and a 15% higher risk of developing kidney failure requiring replacement therapy such as dialysis or transplantation.
April Research Highlights
This tipsheet highlights the latest medical discoveries and faculty news at Cedars-Sinai. Links to full news releases are included with each item.
Statins Likely Not Helpful In Reducing Covid-19 Mortality or Severity
Findings from a recent Johns Hopkins Medicine-led study of nearly 4,500 patients hospitalized with COVID-19 over a four-month period provide a stronger case for a very different conclusion: Statins likely did not confer any impact — positive or negative — on COVID-related mortality and may be associated with an significantly increased risk — nearly 1 chance in 5 — of more serious illness.
January Issue of The American Journal of Gastroenterology Includes New Clinical Guideline on Irritable Bowel Syndrome
The January issue of The American Journal of Gastroenterology is now available and features new clinical research across a wide range of GI and hepatology topics, including NAFLD, colorectal cancer screening, GERD, post-COVID-19-associated functional GI disorder surges, celiac disease, and more.
Yes or No: Forcing a Choice Increased Statin Prescribing for Heart Disease Patients
Adding an “active choice” nudge to the electronic health record increased statin prescribing for patients with heart disease, but not for those “at-risk”
Statins Reduce COVID-19 Severity, Likely by Removing Cholesterol That Virus Uses to Infect
Analyzing anonymized patient medical records, UC San Diego researchers discovered that cholesterol-lowering statins reduced risk of severe COVID-19 infection, while lab experiments uncovered a cellular mechanism that helps explain why.
Study Explores Statins’ Role in Insulin Resistance
Article title: Statins activate the NLRP3 inflammasome and impair insulin signalling via p38 and mTOR Authors: Brandyn D. Henriksbo, Akhilesh K. Tamrakar, Jobanjit S. Phulka, Nicole G. Barra, Jonathan D. Schertzer From the authors: “We propose that dysregulated [mammalian target of rapamycin]…
Common cholesterol drugs could slow spread of breast cancer to brain
A new study from the University of Notre Dame shows drugs used to treat high cholesterol could interfere with the way breast cancer cells adapt to the microenvironment in the brain, preventing the cancer from taking hold.
Statins Starve Cancer Cells to Death
More than 35 million Americans take statin drugs daily to lower their blood cholesterol levels. Now, in experiments with human cells in the laboratory, researchers at Johns Hopkins Medicine have added to growing evidence that the ubiquitous drug may kill cancer cells and have uncovered clues to how they do it.
15-Year Study Finds Treatment Gaps Exist for Patients with Peripheral Arterial Disease; More Consistent Use of Life-Saving Medications Recommended
A new 15-year study by researchers at the Intermountain Healthcare Heart Institute in Salt Lake City found that patients with peripheral arterial disease may not be prescribed life-saving medications at the same rate as for other heart conditions.
New study may have the reason why heart medication gives muscle pain
The McMaster research team found muscle cells treated with statins released the amino acid called glutamate at much higher levels than muscle cells that were untreated. As glutamate is a potent activator of muscle pain receptors, this release was proposed to trigger the sensation of muscle pain.
Cholesterol Medication Could Invite Diabetes, Study Suggests
Patient data shows association between statins and type 2 diabetes COLUMBUS, Ohio – A study of thousands of patients’ health records found that those who were prescribed cholesterol-lowering statins had at least double the risk of developing type 2 diabetes. …