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UrduNatural killer (NK) cells engineered to express interleukin-21 (IL-21) demonstrated sustained antitumor activity against glioblastoma stem cell-like cells (GSCs) both in vitro and in vivo, according to new research from The University of Texas MD Anderson Cancer Center.
Tag: In Vitro
How a New Blood-Vessel-on-a-Chip Can Help Researchers Further Understand Vascular Malformations
Vascular malformations (VMs), a group of rare genetic disorders that causes an abnormal formation of veins, arteries, capillaries, or lymphatic vessels at birth, can interfere with the duties of our circulatory system by causing blockages, poor drainage, and the formation of cysts and tangles.
ACI Workshop to Examine New Test Methods for Cleaning Product Safety
What are the best available non-animal scientific methods to assess the potential hazard of respiratory irritation throughout the life cycle of cleaning products?
The American Cleaning Institute is hosting a workshop March 2, 2023 in Arlington, Virginia that will bring together leading experts who will explore “New Approach Methods (NAMs) for the In Vitro Assessment of Cleaning Products for Respiratory Irritation.”
New Approach Methodologies, Single Cell RNAseq, and More Featured in 2021 Toxicological Sciences
Toxicological Sciences delivers cutting-edge research in toxicology in the areas of clinical and translational toxicology, emerging technologies, and more in the August 2021 issue.
ACSM Annual Meeting Research Highlights for June 3
ACSM’s comprehensive sports medicine and exercise science conference takes place virtually from June 1 to 5 with programming covering the science, practice, public health and policy aspects of sports medicine, exercise science and physical activity.
Predictive Toxicology for Healthy Children
New Approach Methodologies (NAMs) can quickly and efficiently collect a large amount of information about the potential toxicity of chemicals without the use of intact animals, but there are challenges to using them to evaluate developmental toxicity compared with adult…
Combining Best of Both Worlds for Cancer Modeling
Treatment options for many types of cancers remain limited, due partly to the in vitro tools used to model cancers and that results from animal studies do not always translate well to human disease. These shortcomings point to a clear need for a better, patient-specific model. Researchers suggest bioengineered microscale organotypic models can address this need. They discuss the advantages and capabilities of this technique, as well as its challenges, in the journal APL Bioengineering.
LLNL develops first-ever living, 3D-bioprinted aneurysm to test surgical treatments
A Lawrence Livermore National Laboratory team, along with their collaborators, has become the first to produce a living, bioprinted aneurysm outside of the human body, perform a medical procedure on it, and observe it respond and heal as it would in an actual human brain.
Tissue-Engineering, Estrogenic Chemical–Induced Responses, and Life-Stage Physiologically Based Pharmacokinetic Modeling Featured in January 2020 Toxicological Sciences
In addition to research exploring such areas as biomarkers, nano- and neurotoxicology, and developmental and reproductive toxicology, the January 2020 issue of Toxicological Sciences features a new article category, ToxPoint, to underscore cutting-edge topics in toxicology.
Randox QC unveils brand new multi-analyte commutable Acusera Infectious Disease Controls
Randox Quality Control is set to introduce its brand new Acusera Infectious Disease (Serology) Controls at the American Association for Clinical Chemistry 2019.
Multiplex biochip for accurate differentiation of stroke types launched at AACC
A ground-breaking new test which improves the accuracy of stroke diagnosis has been developed by Randox scientists.