The November issue of The American Journal of Gastroenterology features several articles examining the association between common conditions or treatments and the risk for disease development, including a study on the association between higher body mass index and increased risk for early-onset colorectal cancer, and a population study on proton pump inhibitors and all-cause mortality.
Tag: Gastroenterology
MEDIA ADVISORY: Featured Lectures at the 2021 ACG Annual Scientific Meeting and Postgraduate Course
The featured lectures at the 2021 ACG Annual Scientific Meeting and Postgraduate Course showcase innovative and challenging issues in clinical gastroenterology. This year’s lectures include a special Keynote Address delivered by Dr. Thomas Frieden, CEO of Resolve to Save Lives and former director of the US Centers for Disease Control and Prevention.
Two Studies Seek to Go Beyond the GIST of Intestinal Tract Cancer
UC San Diego researchers identify the mutational drivers for gastrointestinal stroma tumors in the stomach and find a potential drug to treat a subset of GIST tumors afflicting the young.
International experts call for a unified public health response to NAFLD and NASH epidemic
Patients with obesity or type 2 diabetes are at a higher risk of developing NAFLD and NASH.
Senator Toni Atkins Visits Hospital to Recognize Plans for New Hillcrest Campus
Senate President Pro Tempore Toni Atkins visited UC San Diego Medical Center today to recognize a $30 million allocation in the 2021-2022 California state budget that will support the redevelopment of the new Hillcrest hospital.
ASMBS Foundation awards research grants for studies related to COVID-19 & obesity
Newberry, FL – July19, 2021– The American Society for Metabolic and Bariatric Surgery (ASMBS) Foundation today announced it has awarded two research grants totaling $50,000 to study the effects of obesity on COVID-19 infections in adolescents and the increasing use…
Pathogens get comfy in designer goo
Rice, Baylor labs use custom hydrogels to mimic insides of intestines, study infectious bacteria
No IgA leads to intestinal inflammation in mice
Tokyo, Japan – While researchers have known for years that immunoglobulin A (IgA) is important for gut health, it has remained unclear exactly what role it plays in preventing infection and disease. But now, researchers from Japan have found that…
American College of Gastroenterology Announces New Co-Editors-in-Chief of Red Journal
The American College of Gastroenterology today announced the new Co-Editors-in-Chief of The American Journal of Gastroenterology, Dr. Jasmohan Bajaj and Dr. Millie Long, who will assume their new roles with the January 2022 issue.
Scientists identify new gut-liver drug recycling process
Implications for developing treatments for intestinal diseases
Keeping the world up to date on irritable bowel syndrome research in China
Scientists condense Chinese studies over the past decade on this common gastrointestinal disorder in a review article
Species of gut bacteria linked to enhanced cognition and language skills in infant boys
Alberta study offers compelling new evidence pointing to the importance of gut bacteria for neurodevelopment
Changes in gut microbiome in longitudinal study of infants precede onset of celiac disease
Pre-clinical changes in the gut could inform treatment and prevention.
Mucus and mucins may become the medicine of the future
Many people instinctively associate mucus with something disgusting, but in fact, it has incredibly many valuable functions for our health. It keeps track of our important intestinal flora and feeds the bacteria. It covers all internal surfaces of our body,…
Chemo upsets gut health in cancer patients
New research in BMC Cancer has shown myelosuppressive chemotherapy destabilises gut microbiome in patients with solid organ cancers.
Colorectal Cancer Risk May Increase with Lower Exposure to UVB Light
University of California San Diego School of Medicine researchers identified a possible link between inadequate exposure to ultraviolet-B (UVB) light from the sun and an increased risk of colorectal cancer.
Missing bile ducts offer clues to mechanism of liver injury
PITTSBURGH, July 6, 2021 – Scientists from the University of Pittsburgh School of Medicine described a new phenomenon in which the deletion of a single gene involved in liver embryogenesis completely wipes out bile ducts of newborn mice. But despite…
July Issue of The American Journal of Gastroenterology Includes Analysis of Psychological Comorbidities and Irritable Bowel Syndrome Prognosis
The July issue of AJG includes an examination of psychological comorbidities and the prognosis of individuals with IBS, as well as clinical research and reviews on cirrhosis, GERD, pediatrics, celiac disease, probiotics, GI quality improvement, NASH, and more.
Engineered yeast probiotic developed to treat inflammatory bowel disease
Designed from the yeast used to make beer, ‘Y-bots’ can target inflammation, tissue scarring and disturbances in the balance of microbes living in the gut
Seeking a treatment for IBS pain in tarantula venom
For patients who have inflammatory bowel syndrome (IBS), the condition is literally a pain in the gut. Chronic — or long-term — abdominal pain is common, and there are currently no effective treatment options for this debilitating symptom. In a…
Postop chylothorax treated with intranodal lymphangiography, ethiodized oil
High-dose intranodal lymphangiography with ethiodized oil is a safe and effective procedure for treating high-output postsurgical chylothorax with chest tube removal in 83% of patients
Kirigami-inspired stent offers new drug delivery method for tubular organs
Stretchable, snakeskin-like design features pop-out needles to allow circumferential and longitudinal delivery of therapeutics in challenging situations
Restoring gut microbes missing in early life dysbiosis can reduce the risk of colitis in genetically prone mice
A new study at the University of Chicago has determined that restoring a single microbial species — Bacteroides sp. CL1-UC (Bc) — to the gut microbiome at a key developmental timepoint can prevent antibiotic-induced colitis in a mouse model of the condition.
International travel may spread destination-specific antimicrobial resistance genes
Travellers abroad may pick up bacteria and other vectors containing genes conferring antimicrobial resistance which remain in the gut when returning to their home country, according to a study published in Genome Medicine . A team of researchers at Washington…
Restoring gut microbes missing in early life dysbiosis can reduce risk of colitis in mice
A study in mice found that microbial imbalances induced by early exposure to antibiotics could be corrected by adding back a single strain of Bacteroides to improve the dysbiosis and prevent colitis
Mothers transmitting hepatitis B to children as broken hospital procedures plague Europe
Procedures to prevent the direct transmission of hepatitis B virus (HBV) from mother to child, particularly during and after pregnancy, have significant fragmentation and gaps
Screening reveals coeliac disease cases in children have doubled in 25 years
Mass screening of school age children has led to significantly higher numbers of coeliac disease cases being diagnosed, according to a new study presented today at the 6th World Congress of Paediatric Gastroenterology, Hepatology and Nutrition
Study on Green Kiwifruit to Treat Chronic Constipation and New ACG Clinical Guidelines on C. difficile Infection Featured in the June Issue of The American Journal of Gastroenterology
The June issue of AJG includes articles on the effectiveness of OTC therapies and green kiwifruit as a dietary therapy for chronic constipation, as well as new ACG Guidelines on the Prevention, Diagnosis, and Treatment of C. difficile infections, and more.
Fish oil taken during pregnancy boosts brain function in children at age 10
(Geneva, 4 June 2021) Children born to mothers who took fish oil in their pregnancies have been shown to have faster problem-solving skills and better attention focus at age 10, according to findings from a study presented today.
Diet plays critical role in NASH progressing to liver cancer in mouse model
When fed diet high in fat and cholesterol, mice that overate became obese, diabetic and developed NASH, which progressed to kidney and cardiovascular disease and liver cancer
A review on the current updates in the field of gastroenterology and hepatology
Knowledge in medicine is a very dynamic process due to the continuing progress in this field. New developments influence research, but also the clinical practice. Hence the continuous need for improvement in the field in which we work is required.…
Exoskeleton-assisted walking may improve bowel function in people with spinal cord injury
Research team shows that physical intervention plans that include walking, not just standing, may enhance multiple measures of bowel function
Microbial gene discovery could mean greater gut health
URBANA, Ill. – As the owner of a human body, you’re carrying trillions of microbes with you everywhere you go. These microscopic organisms aren’t just hitching a ride; many of them perform essential chemical reactions that regulate everything from our…
AGA recommends early use of biologics in patients with moderate-to-severe Crohn’s disease
The American Gastroenterological Association (AGA) issues new clinical guidelines on drug therapy for the management of moderate-to-severe luminal and fistulizing Crohn’s disease.
Good bacteria can temper chemotherapy side effects
Naturally occurring gut bacteria can clean up chemo toxins in the body, study finds
Unforeseen links to chronic pancreatitis found in cancer-related signals
Researchers at Osaka University reveal the molecular mechanisms that underlie the development and progression of chronic pancreatitis and identify a therapeutic target for further research
IBS patients’ symptoms improved under COVID-19 lockdown orders
Unexpected reduction in symptoms may result from lower stress and more control over diet at home
Smart toilet may soon analyze stool for health problems
Artificial intelligence tool can be used for long-term tracking and management of chronic gastrointestinal ailments
Long-term gluten intake, cognitive function among women
What The Study Did: This observational study found no association between long-term dietary intake of gluten and cognitive function among a large group of middle-age women without celiac disease. Authors: Andrew T. Chan, M.D., M.P.H., of Massachusetts General Hospital and…
Carbohydrate ‘cage’ allows precise drug delivery to the gastrointestinal tract
A GlycoCage technology developed by GlycoNet researchers aims to improve current treatments for inflammatory bowel disease
Western diet found to impair function of immune cells in the gut
Cleveland Clinic-led researchers publish findings in Cell Host & Microbe
’45 is the new 50′ as age for colorectal cancer screening is lowered
BOSTON – Prompted by a recent alarming rise in cases of colorectal cancer in people younger than 50, an independent expert panel has recommended that individuals of average risk for the disease begin screening exams at 45 years of age…
USPSTF lowers recommended ages for colorectal cancer screening
Bottom Line: The U.S. Preventive Services Task Force (USPSTF) recommends that adults ages 45 to 75 be screened for colorectal cancer, lowering the age for screening that was previously 50 to 75. The USPSTF also recommends that clinicians selectively offer…
Western diet may increase risk of gut inflammation, infection
Diet rich in sugar, fat damages immune cells in digestive tracts of mice
Which medications are most toxic to the liver?
A new study published in the British Journal of Clinical Pharmacology ¬provides insights on how common hospitalized patients develop liver injury from taking different medications. When investigators analyzed the records of 156,570 hospitalized patients, they found 499 cases of drug-induced…
May Issue of The American Journal of Gastroenterology Contains Two Updated ACG Clinical Guidelines: Upper GI Bleeding and Drug-Induced Liver Injury
newly issued updates to ACG Clinical Guidelines on Upper Gastrointestinal and Ulcer Bleeding and Diagnosis and Management of Idiosyncratic Drug-Induced Liver Injury. In addition to the guidelines, this issue features clinical research on esophageal cancer, obesity, telemedicine, celiac disease, Crohn’s disease, and more.
Intestinal polyps in close relatives can increase risk of colorectal cancer
Cancer of the colon and rectum is one of the deadliest forms of cancer, and has in recent years affected growing numbers of young people. In the largest registry study to date, researchers at Karolinska Institutet in Sweden and Harvard…
Increased use of minimally invasive non-endoscopic tests for Barrett’s esophagus screening
Embargoed news from Annals of Internal Medicine
A glimmer of hope: New weapon in the fight against liver diseases
Niigata, Japan–Researchers from Niigata University , the University of Tokyo, Osaka University and Tokyo Medical University, Japan have developed a new approach that could revolutionize the treatment, prevention, and possibly reversal of the damages caused by liver diseases. This novel…
SARS-CoV-2 curtails immune response in the gut
Scientists transform human intestinal cells into ‘mini guts’ to follow infection process