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UrduScientists transform human intestinal cells into ‘mini guts’ to follow infection process
Tag: Gastroenterology
Personalized, 3D printed shields developed to protect patients during radiation therapy
To reduce tissue injury side effects from radiation therapy, a research team is developing 3D-printed gastrointestinal radioprotective devices that can be generated from patient CT scans
Probiotic Lactobacillus acidophilus shows promise for treating inflammatory bowel disease and other
Probiotic strain LA1 has a therapeutic effect that both prevents and treats intestinal inflammatory disorders caused by “leaky gut,” report researchers in The American Journal of Pathology
April Issue of The American Journal of Gastroenterology Highlights Dietary Interventions to Address Common Upper GI Complaints
Also: Opioid prescription rates for GI conditions, evolving changes in fecal microbiota transplantation risk, endoscopy challenges in patients with surgically altered anatomy, insulin resistance and pancreatic cancer risk, comparing clinician and insurer perspectives to managing IBS, and more.
AGA recommends intragastric balloons as an additional weight loss strategy for obese patients
The American Gastroenterological Association (AGA) issues formal recommendations on the use of intragastric balloons for obesity
Gut microbiota in cesarean-born babies catches up
Infants born by cesarean section have a relatively meager array of bacteria in the gut. But by the age of three to five years they are broadly in line with their peers.
Possible trigger for Crohn’s disease identified
Adherent-invasive E-coli (AIEC) strongly implicated
Gut microbiota in cesarean-born babies catches up
Infants born by cesarean section have a relatively meager array of bacteria in the gut. But by the age of three to five years they are broadly in line with their peers. This is shown by a study that also…
Targeted opioid that hones in on inflamed tissues stops colitis pain without side effects
Study in mice points to promising treatment for pain in inflammatory bowel disease
Diets high in heat-treated foods increase risk of chronic kidney disease, rat study shows
Processed foods drive intestinal barrier permeability and microvascular diseases
Mount Sinai study reveals genetic and cellular mechanisms of Crohn’s disease
Mount Sinai researchers have identified genetic and cellular mechanisms of Crohn’s disease, providing new insights for future treatments that could offer a tailored approach to patients with the chronic inflammatory disease, according to a study published in Nature on March…
Open-label placebo works as well as double-blind placebo in irritable bowel syndrome
First-of-its-kind study compares performance of open-label placebo to blinded placebo
High-fiber diet may play a role in controlling the inflammation associated with COVID-19
In vitro treatment of cells with these molecules reduced the expression of a gene that plays a key role in viral cell entry and a cytokine receptor.
Chronic inflammatory liver disease: cell stress mechanisms identified
International study led by MedUni Vienna appears in “Hepatology”
How much peanut does it take to trigger an allergic reaction?
University of Cincinnati toxicologist says finding an ‘eliciting dose’ may help those who suffer mild or moderate allergic reactions to peanut
New study published in Science maps wildlife microbiota
Discovering millions of previously unknown potential human therapeutics
A T-cell stimulatory protein and interleukin-10 synergize to prevent gut inflammation
This study will aid the understanding of, and future research on, inflammatory bowel disease, which afflicts about 1.6 million Americans
Aging cells in abdominal fluid cause increased peritoneal dissemination of gastric cancer
Closing in on complete control over peritoneal dissemination of cancer.
Study estimates rising global burden of gallbladder and biliary tract cancer
Although cancers that occur in the gallbladder or bile ducts are rare, their rates are increasing. A recent study provides details on the burden of gallbladder and biliary tract cancer (GBTC) across 195 countries and territories from 1990 to 2017.…
New Barrett’s esophagus monitoring method could aid in easier and more precise prognoses
CLEVELAND–A new technique for sampling and testing cells from Barrett’s esophagus (BE) patients could result in earlier and easier identification of patients whose disease has progressed toward cancer or whose disease is at high risk of progressing toward cancer, according…
Common, serious gut disorder is under- and often misdiagnosed
A serious digestive problem that is underdiagnosed–rumination–is highlighted in a new study.
Reversing cancer’s gluttony
Researchers report that pancreatic cancer tumors use multiple mechanisms to avoid starvation, suggesting a new target for treating a very difficult and deadly disease
A raw diet for under 6-month-old puppies may reduce the risk of inflammatory bowel disease
According to a study conducted at the University of Helsinki, a raw diet from the late stages of suckling to roughly two months of age may reduce the prevalence of inflammatory bowel disease (IBD) in dogs later in life. In…
Scientist gets $2 million grant to study how inflammation, gut microbiota promote metabolic syndrome
ATLANTA–Dr. Andrew Gewirtz, a professor in the Institute for Biomedical Sciences at Georgia State University, has received a four-year federal grant just over $2 million to study how inflammation and altered gut microbiota, the microorganisms living in the intestine, influence…
Surgery should remain as mainstay of treatment for acute uncomplicated appendicitis
An RCSI study conducted in Beaumont Hospital in Dublin has found that surgery, rather than antibiotics-only, should remain as the mainstay of treatment for acute uncomplicated appendicitis. Published in the Annals of Surgery and led by researchers from the RCSI…
Of mice and men and their different tolerance to pathogens
A mouse intestine-on-chip discovery platform enables the modeling of host-microbiome relations, infectious disease modeling, and the identification of tolerance-promoting species
CT colonography most effective noninvasive colorectal cancer screening test
Compared with multi-target stool-DNA and fecal immunochemical test, CT colonography with 10 mm threshold most effectively targets advanced neoplasia–preserving detection while decreasing unnecessary colonoscopies
Probiotics increase gut bacteria diversity in extremely preterm infants
Extremely preterm infants can suffer from a life-threatening inflammation of the gut. A new clinical study has shown that supplements of a lactic acid bacterium may have positive effects by increasing the diversity of intestinal bacteria in these infants. The…
Foodborne fungus impairs intestinal wound healing in Crohn’s disease
Study in mice, people suggests new approaches to treating symptoms
Cleveland Clinic researchers discover microbial infection that impairs healing in Crohn’s disease
Study published in Science lays the groundwork for new strategies to treat or prevent the disease
Scientists report gastrointestinal manifestations and mechanisms of COVID-19
Recently, Prof. ZHU Shu from University of Science and Technology of China (USTC) of CAS and Prof. Richard A. Flavell from Yale University were invited to publish a review article in Nature Reviews Gastroenterology and Hepatology.
Microbes may hold the key for treating neurological disorders
When we think about the causes of neurological disorders and how to treat them, we think about targeting the brain. But is this the best or only way? Maybe not. New research by scientists at Baylor College of Medicine suggests…
Therapy Sneaks into Hard Layer of Pancreatic Cancer Tumor and Destroys it From Within
Researchers at University of California San Diego School of Medicine and Moores Cancer Center demonstrated that a new tumor-penetrating therapy could enhance the effects of chemotherapy, reduce the spread of pancreatic cancer and increase survival in animal models.
March Special Issue of The American Journal of Gastroenterology Focuses on Women’s Health in Gastroenterology and Hepatology
The March issue of The American Journal of Gastroenterology features new clinical research involving sex and gender, including effects of GI and liver conditions on pregnancy, gender disparities in diet and nutrition, Barrett’s esophagus incidence in women with scleroderma, factors influencing whether women pursue advanced endoscopy careers, endoscopy-related musculoskeletal injuries, sex hormone association with increased prevalence of certain types of cancer, and more.
FDA qualifies C-Path’s Diary for Irritable Bowel Syndrome Symptoms-Constipation (DIBSS-C)
TUCSON, Ariz., March 9, 2021 — Critical Path Institute’s (C-Path) Patient-Reported Outcome (PRO) Consortium announces the qualification of the Diary for Irritable Bowel Syndrome Symptoms-Constipation (DIBSS-C) by the U.S. Food and Drug Administration (FDA). The DIBSS-C was developed by the…
Characterizing different cell types in the upper gastrointestinal tract
Researchers from the group of Hans Clevers identified and characterized rare cell types in the upper gastrointestinal tract. Using single cell RNA sequencing, they studied the cellular composition of the esophagus, stomach and upper part of the small intestine. They…
The gut mycobiome influences the metabolism of processed foods
New research in mice points to a significant role for fungi to shape metabolism, including fat deposition, and metabolic hormones.
Controlling adhesions in the abdomen
Scars inside the abdomen, known as adhesions, form after inflammation or surgery. They can cause chronic pain and digestive problems, lead to infertility in women, or even have potentially life-threatening consequences such as intestinal obstruction. If adhesions develop, they must…
Study reveals details of immune defense guidance system
Results could lead to better drugs used to fight inflammation
Colonoscopy: Yes, This is a Test
Colorectal cancer is the second leading cause of cancer death for both men and women, according to the Centers for Disease Control and Prevention (CDC), even though 90 percent of people who are diagnosed through early testing can be cured.
New journal launched, The International Journal of Gastroenterology & Hepatology Diseases
Bentham Science is pleased to announce the launch of new subscription-based journal, The International Journal of Gastroenterology and Hepatology Diseases. The first issue of the journal will be available online by the start of the year, 2021. Dr. N. Mendez-Sanchez,…
Machine learning method identifies precancerous colon polyps
OAK BROOK, Ill. – A machine learning algorithm helps accurately differentiate benign and premalignant colorectal polyps on CT colonography scans, according to a study published in the journal Radiology . Colorectal cancer is among the three most common causes of…
Acid reflux disease may increase risk of cancers of the larynx and esophagus
Results from a large prospective study indicate that gastroesophageal reflux disease (GERD), which also causes heartburn symptoms, is linked with higher risks of various cancers of the larynx (or voice box) and esophagus. The study is published early online in…
Amoxicillin-clavulanate safe and effective compared with metronidazole-with-fluoroquinolone for dive
Embargoed news from Annals of Internal Medicine
First multi-whole-genome study of IBD in African Americans
Anaylsis shows different genetic risk landscape for IBD
Chatter Between Cell Populations Drives Progression of Gastrointestinal Tumors
Researchers at University of California San Diego School of Medicine identified new therapeutic targets for gastrointestinal stromal tumors (GISTs) that could lead to new treatment options for patients.
TGen-led study confirms cell-free DNA in urine as potential method for cancer detection
If successful, non-invasive method could transform detection and treatment outcomes
Chatter between cell populations drives progression of gastrointestinal tumors
Study results could lead to more effective treatment options for GIST patients, which are currently limited
New potential therapy for Crohn’s disease in children
Anti-inflammatory nanotherapy produced promising results in a rodent model
New study reports activated B. infantis EVC001 improves health outcomes in preterm infants
Study quantifies unprecedented reduction in enteric inflammation, diaper rash and antibiotic use via beneficial gut remodeling