Study quantifies unprecedented reduction in enteric inflammation, diaper rash and antibiotic use via beneficial gut remodeling
Tag: Gastroenterology
Role of diet in risk of colorectal cancer
What The Study Did: Researchers examined the strength of the evidence from published meta-analyses of observational studies that looked at the association between diet and the risk of colorectal cancer. Authors: Nathorn Chaiyakunapruk, Pharm.D., Ph.D., of the University of Utah…
Zika vaccine candidate shows promise in phase I trial
Embargoed news from Annals of Internal Medicine
Going the distance–insights into how cancer cells spread
Most tumors consist of a heterogenous mix of cells. Genetic mutations found only in some of these cells are known to aid with the spread and progression of cancer. However, oncologists often find that when tumors metastasize to distant organs,…
A novel approach to determine how carcinogenic bacteria find their targets
Treatments targeting the motility system of the bacteria could eliminate the risk of antibiotic resistance
Regular walnut consumption may reduce negative outcomes of H. pylori infection
FOLSOM, Calif., February 9, 2021 – A new animal study, published in the Journal of Clinical Biochemistry and Nutrition , suggests regular walnut consumption may be a promising intervention for reducing negative outcomes associated with Helicobacter pylori (H. pylori) infection,…
Scientists switch on tissue repair in inflammatory bowel disease
A method that instructs immune system cells to help repair damaged tissues in the intestine has been developed by researchers at KU Leuven and Seoul National University. This opens the way for more effective treatment of inflammatory bowel disease, including…
Fungi in the gut prime immunity against infection
Common fungi, often present in the gut, teach the immune system how to respond to their more dangerous relatives, according to new research from scientists at Weill Cornell Medicine. Breakdowns in this process can leave people susceptible to deadly fungal…
Study identifies ‘Achilles heel’ of bacteria linked to Crohn’s disease
The discovery of an “Achilles heel” in a type of gut bacteria that causes intestinal inflammation in patients with Crohn’s disease may lead to more targeted therapies for the difficult to treat disease, according to Weill Cornell Medicine and NewYork-Presbyterian…
Nehandertals’ gut microbiota and the bacteria helping our health
Neanderthals’ gut microbiota already included some beneficial micro-organisms that are also found in our own intestine. An international research group led by the University of Bologna achieved this result by extracting and analysing ancient DNA from 50,000-year-old faecal sediments sampled…
Fecal microbiota transplants help patients with advanced melanoma respond to immunotherapy
For patients with cancers that do not respond to immunotherapy drugs, adjusting the composition of microorganisms in the intestines–known as the gut microbiome–through the use of stool, or fecal, transplants may help some of these individuals respond to the immunotherapy…
Year or More Delay Between Abnormal, At-Home Screening and Colonoscopy Increases Cancer Risk
A new study by researchers at University of California San Diego School of Medicine found delayed time between abnormal stool-based screening and subsequent colonoscopy was associated with an increased risk of a cancer diagnosis and death from colorectal cancer.
Delaying colonoscopy following abnormal stool test increases risk of colorectal cancer
Study included cohort of more than 200,000 veterans
American Gastroenterological Association announces 2021 AGA recognition prizes
Dr. Michael Camilleri of the Mayo Clinic receives the highest honor of the Julius Friedenwald Medal
Deep Vision: Near-infrared imaging and machine learning can identify hidden tumors
Near-infrared hyperspectral imaging combined with machine learning can visualize tumors in deep tissue and covered by a mucosal layer, scientists show
Year delay between abnormal, at-home screening and colonoscopy increases cancer risk
Study finds risk of late-stage colon cancer increased at 16 months by approximately 33%
Study finds potential therapeutic targets to inhibit colorectal cancer progression
Nagoya University researchers and colleagues have revealed that colorectal cancer tissues contain at least two types of fibroblasts (a type of cells found in connective tissue), namely, cancer-promoting fibroblasts and cancer-restraining fibroblasts, and that the balance between them is largely…
Our gut-brain connection
‘Organs-on-a-chip’ system sheds light on how bacteria in the human digestive tract may influence neurological diseases
Mechanism for how pancreatic cancer evades immunotherapy elucidated
WASHINGTON — Pancreatic cancer, one of the most lethal of all cancers, is capable of evading attacks by immune cells by changing its microenvironment so that the immune cells suppress, rather than support, an attack on the tumor. The scientists…
Gut microbiota reveals whether drug therapies work in inflammatory bowel diseases
The prevalence of inflammatory bowel diseases has significantly increased both in Finland and globally.
New partnership announced to develop first prognostic tests for pediatric Crohn’s disease
The Crohn’s and Colitis Foundation enters partnership with LifeArc to develop first clinical tests to predict disease course and response to treatment in pediatric Crohn’s patients
Researchers develop wearable sweat sensors to predict IBD flare-ups
Plus more groundbreaking inflammatory bowel diseases (IBD) research presented at the Crohn’s & Colitis Congress®
Inflamed environment is C. diff paradise
A new study from North Carolina State University shows that the inflammation caused by Clostridioides difficile ( C. diff ) infection gives the pathogen a two-fold advantage: by both creating an inhospitable environment for competing bacteria and providing nutrients that…
Green med diet cuts non-alcoholic fatty liver disease by half – Ben-Gurion U. study
BEER-SHEVA, Israel…January 18, 2021 – A green Mediterranean (MED) diet reduces intrahepatic fat more than other healthy diets and cuts non-alcoholic fatty liver disease (NAFLD) in half, according to a long-term clinical intervention trial led by Ben-Gurion University of the…
Researcher Developing Scoring System to Redefine How U.S. Patients are Prioritized for Liver Transplant
Researchers with Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine are collaborating with faculty at the University of Pennsylvania to develop a risk score that more comprehensively prioritizes liver cancer patients for transplantation.
NIH scientists study salmonella swimming behavior as clues to infection
WHAT: Salmonella enterica serovar Typhimurium bacteria ( S. Typhimurium) commonly cause human gastroenteritis, inflammation of the lining of the intestines. The bacteria live inside the gut and can infect the epithelial cells that line its surface. Many studies have shown…
Ovarian cancer cells adapt to their surroundings to aid tumor growth
New study brings us closer to targeted treatments that suppress the growth of ovarian cancer, which is often fatal, as early stages are hard to detect
Scientists reveal mechanism that causes irritable bowel syndrome
KU Leuven researchers have identified the biological mechanism that explains why some people experience abdominal pain when they eat certain foods. The finding paves the way for more efficient treatment of irritable bowel syndrome and other food intolerances. The study,…
HEALTHCARE NUTRITION COUNCIL LEADS THE WAY ON MEDICAL FOOD DISCUSSIONS
Announcement of Publication of Workshop Proceedings
Gut microbes may antagonize or assist in anorexia
Review highlights evidence that the microbial community in our gut may significantly contribute to anorexia and represents a new way to treat it
Scientists study use of abundant enzyme in tumor cells to monitor cancer treatment
After 14 years studying the action of the enzyme LMWPTP in tumor cells, Brazilian researchers conclude that the molecule is associated with chemotherapy resistance and metastasis.
Researchers engineer novel disease model to identify potential targets for ulcerative colitis drugs
Cleveland Clinic research team publishes findings in Nature Communications
Clinical trial of antibiotic strategies for uncomplicated acute appendicitis
What The Study Did: This randomized clinical trial compares the effects of two antibiotic strategies (oral moxifloxacin versus intravenous ertapenem followed by oral levofloxacin) on hospital discharge without surgery and recurrent appendicitis over one year among adults presenting to the…
January Issue of The American Journal of Gastroenterology Includes New Clinical Guideline on Irritable Bowel Syndrome
The January issue of The American Journal of Gastroenterology is now available and features new clinical research across a wide range of GI and hepatology topics, including NAFLD, colorectal cancer screening, GERD, post-COVID-19-associated functional GI disorder surges, celiac disease, and more.
Study: E-Cigarettes Trigger Inflammation in the Gut
Chemicals used for vaping break down zipper-like junctions between cells in the gut, leading to chronic inflammation and potential for other health concerns.
C-Path PRO Consortium measure used to support an FDA-approved label claim
Diary for Irritable Bowel Syndrome Symptoms-constipation is the first patient-reported outcome consortium measure used to support an FDA-approved label claim
Diet and lifestyle guidelines can greatly reduce gastroesophageal reflux disease symptoms
A large-scale, longstanding study of diet, lifestyle and health has found that by adhering to specific guidelines, women can reduce more than one-third of incidence of symptoms
Frailty is a factor in higher mortality for women awaiting liver transplants
More exercise, more protein may narrow the gender gap, researchers say
Multi-Population Risk Scores Could Improve Risk Prediction for Inflammatory Bowel Diseases, Study Finds
New study illustrates how studying diverse populations can help predict patient outcomes and reduce health disparities
Light flips genetic switch in bacteria inside transparent worms
Light-controlled genes could reveal how gut bacteria impact health
Visible hydrogels for rapid hemorrhage control and monitoring
(LOS ANGELES) – There are many different events which may lead to excessive and uncontrolled bleeding within the body. This can occur as a result of inflammation and ulcerations, abnormalities in the blood vessels or trauma-related injuries. Individuals with predisposing…
Potential preventative treatment demonstrated for Crohn’s disease
This potential preventive treatment for Crohn’s disease was tested on a mouse model and on immune-reactive T cells from patients with Crohn’s disease.
Join us virtually: 2021 Crohn’s & Colitis Congress®
Dec. 18, 2020 — The Crohn’s & Colitis Congress®, the premier conference for inflammatory bowel disease (IBD) health care providers and researchers, invites media to register for the virtual 2021 meeting experience. A partnership of the Crohn’s & Colitis Foundation…
Patients don’t receive recommended follow-up care after weight loss surgery
Peer reviewed – observational study – humans
The American College of Gastroenterology Issues Its First Clinical Guideline on Management of Irritable Bowel Syndrome
The new guideline recommends is a positive diagnostic strategy involving a careful history, physical examination, and limited diagnostic testing, which can substantially shorten time to appropriate therapy and be more cost-effective for patients.
A comprehensive review of early-onset colorectal SEER data is the first to specifically assess adeno
Embargoed news from Annals of Internal Medicine
Compound derived from thunder god vine could help pancreatic cancer patients
TGen-led study indicates drug attacks ‘super-enhancers’ in the DNA of cancer cells and in the stromal cocoon that hides the tumor from the immune system
Beta-blockers display anti-inflammatory effects in advanced liver disease
Beneficial effects on systemic inflammation translate into improved clinical outcomes
Four ERC Consolidator Grants for KU Leuven researchers
The European Research Council (ERC) has awarded its Consolidator Grants. Four KU Leuven researchers are among this year’s recipients in Belgium: breast cancer researcher Christine Desmedt, computer scientist Tias Guns, chemical engineer Simon Kuhn, and psychiatrist Lukas Van Oudenhove. ERC…
UBCO researchers suggest stool transplants can battle serious infections
Genetic analysis helps ensure successful fecal microbiota transplants