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UrduResults could help boost immunization rates during and beyond pandemic among key health care workers
Tag: Clinical Trials
New study: Lack of consideration of sex and gender in COVID-19 clinical studies
Although Covid-19 affects men and women differently, the large majority of current clinical studies of SARS-CoV-2 and COVID-19 makes no mention of sex/gender. Indeed, only a fraction, 4 percent, explicitly plan to address sex and gender in their analysis, concludes…
American Society for Radiation Oncology (ASTRO) to host Annual Meeting in Chicago 10/24-27
#ASTRO21 will be the first major medical conference in the city; a curated digital program also will be offered for remote attendees
Stroke treatment may backfire when kidneys don’t work well
Researchers at the National Cerebral and Cardiovascular Center in Japan show that excessive blood pressure reduction for acute intracerebral hemorrhage is risky in people with decreased kidney function Suita, Japan — Stroke and chronic kidney disease are both difficult to…
The Lancet: CoronaVac COVID-19 vaccine is safe and protects against disease, interim analysis
Interim data from a phase 3 trial of a COVID-19 vaccine developed in China (CoronaVac) suggests that two doses offer 83.5% protection against symptomatic COVID-19. The preliminary findings, published in The Lancet and presented at this year’s European Congress of…
Reporting of adverse effects in drug trials has only improved slightly in 17 years, new study shows
Researchers, including academics from the University of York, analysed systematic reviews of 1,200 Randomised Controlled Trials (RCTs) to assess whether reporting had improved over time. However, the information the researchers needed to assess what adverse effects were reported (and how…
Studies explore links between stress, choline deficiency, preterm births, and mental health
CU researchers say the data points to a health care disparity when it comes to caring for Black mothers and their children in the U.S.
Young South Asian heart attack patients more likely to be obese, use tobacco
Increased heart disease prevention education and awareness needed for younger, at-risk patients
Setting COVID-19 drug trials up for success
Clinical studies of COVID-19 drugs may benefit from randomization and early recruitment, model shows
Work like a dream: new anticholinergic drug keeps PTSD flashbacks and nightmares away
Researchers find that central anticholinergic drug trihexyphenidyl can potentially keep away post-traumatic stress disorder-related flashbacks and nightmares
Interleukin-6 antagonists improve outcomes in hospitalised COVID-19 patients
Findings from a study published today [6 July] in the Journal of the American Medical Association ( JAMA ) have prompted new World Health Organization (WHO) recommendations to use interleukin-6 antagonists in patients with severe or critical COVID-19 along with…
Bowel cancer data reinforce need to reduce unnecessary antibiotic use
ESMO World Congress on Gastrointestinal Cancer 2021
Poorer survival in obese colorectal cancer patients possibly linked to lower chemotherapy doses
ESMO World Congress on Gastrointestinal Cancer 2021
New solution for sleep apnoea
Existing medications can reduce severity by ‘at least 30%’
Mefloquine: A promising drug ‘soldier’ in the battle against COVID-19
Scientists propose the repurposing of anti-malarial drug mefloquine to fight the novel coronavirus
Plastic drapes reduce hypothermia in premature babies
Study: Plastic better than cloth for low birth-weight newborns
5-minute workout lowers blood pressure as much as exercise, drugs
Working out just five minutes daily via a practice described as “strength training for your breathing muscles” lowers blood pressure and improves some measures of vascular health as well as, or even more than, aerobic exercise or medication, new CU Boulder research shows.
Managing attention deficit disorder by training the brain
Attention Deficit Hyperactivity Disorder (ADHD) affects about 7% of children, with a two out of three chance of persisting into adulthood.
ACTG announces publication of REPRIEVE sub-study in JAMA Network Open, providing insights into cardiovascular disease risk among people living with HIV
Los Angeles, Calif. – The AIDS Clinical Trials Group (ACTG), the largest global HIV research network, today announced that findings from a sub-study of REPRIEVE (A5332/A5332s, an international clinical trial studying heart disease prevention in people living with HIV) have…
Preliminary results of clinical trial for Crigler-Najjar syndrome
Preliminary results from the European gene therapy trial for Crigler-Najjar syndrome, conducted by Genethon in collaboration with European network CureCN, were presented at the EASL (European Association for the Study of the Liver) annual International Liver Congress on June 26.…
COVID-linked multi-system inflammatory syndrome in children diagnosed more in Black and Latino child
New study identifies key demographic, clinical and biomarker features of MIS-C patients
Demystifying COVID-19
In this book ‘Demystifying COVID-19- understanding of the Disease, its diagnosis and treatment’ basic points are discussed from case examples to the main principles followed in diagnosis and treatment, real scenarios in the course of the disease, issues that need…
Had COVID-19? One vaccine dose enough; boosters for all, study says
A new study in ACS Nano supports increasing evidence that people who had COVID-19 need only one vaccine dose, and that boosters could be necessary for everyone in the future.
New medical director named to lead clinical cancer research
The new medical director for the UC Davis Comprehensive Cancer Center Office of Clinical Research is Dr. Edward Kim who steps into his new position e on July 1, 2021.
Statin therapy not associated with cognitive decline, dementia in older adults, study says
Observational study adds to growing evidence on statins, but randomized trials are still needed
A tapeworm drug against SARS-CoV-2?
Charité conducts clinical trial to test potential new treatment
Childhood BMI may influence poorer health outcomes in adulthood
Adults who had a high BMI in adolescence were at highest risk for Type 2 diabetes and early heart attack
Study shows registry data could support clinical trials
Baseline data elements from DAPT Study strongly agree with CathPCI Registry data
State of the art and future directions in the clinical application of HR-pQCT in adults
A new international guidance on the clinical application of high-resolution peripheral computed tomography (HR-pQCT) offers an important overview of current clinical applications in adults and direction on the interpretation of results
Foresight diagnostics to show vision of the new standard of lymphoma MRD detection at ICML
AURORA, COLORADO, June 16, 2021 — Foresight Diagnostics, the emerging leader in blood-based lymphoma disease monitoring, announced today that clinical performance of its minimal residual disease (MRD) detection platform in diffuse large B-cell lymphoma (DLBCL) will be presented at the…
Reduced-dose gadobutrol vs standard-dose gadoterate for contrast-enhanced brain MRI
A 25% reduced gadobutrol dose demonstrated non-inferior efficacy versus 100%-standard dose of gadoterate for contrast-enhanced brain MRI, particularly in patients undergoing multiple contrast-enhanced examinations
Key Areas of Cancer Research To Be Presented by Thought Leaders at Atlantic Health System’s 2021 Annual Review in Oncology Virtual Symposium
Atlantic Health System Cancer Care will continue its tradition of world-class medical education by hosting its 2021 Annual Review in Oncology Virtual Symposium. The symposium, held via Microsoft Teams with free registration, will take place Saturday, June 26, 2021, from 8 a.m. to 12:30 p.m. ET. Distinguished faculty from some of the nation’s leading cancer centers will summarize the latest advances in six areas of oncology, as presented at the just-completed ASCO conference—the world’s premiere meeting for cancer care professionals and researchers.
New research finds ways to improve accuracy of Lateral Flow Tests
Research published in the journal ACS Materials and Interfaces has provided new understanding of how false-negative results in Lateral Flow Tests occur and provides opportunity for simple improvements to be made. Lateral Flow Devices were introduced late in 2020 on…
Alternate-day intermittent fasting leads to less fat loss than traditional daily energy restriction
An alternate-day intermittent fasting schedule offered less fat-reducing benefits than a matched “traditional” diet that restricts daily energy intake, according to a new, 3-week randomized trial involving 36 participants. The study, which is one of the first to tease apart…
The ISSCR 2021 Annual Meeting starts 21 June
Six days of exceptional stem cell science
Sex differences in COVID-19 outcomes
In a study of more than 10,600 adult patients hospitalized with COVID-19, women had significantly lower odds than men of in-hospital mortality. They also had fewer admissions to the intensive care unit and less need for mechanical ventilation. Women also…
New in Ethics & Human Research, May-June 2021
Underrepresented populations in clinical research, and more
ACTG honors the 40th anniversary of HIV/AIDS, convenes virtual annual meeting
Los Angeles, Calif. – The AIDS Clinical Trials Group (ACTG), the largest global HIV research network, commemorates the 40th anniversary of the initial publication of reports of what came to be known as HIV/AIDS in CDC’s Morbidity and Mortality Weekly…
New studies identify how tuberculosis destroy the lungs and how to protect them
Two new studies have cast unprecedented light on disease processes in tuberculosis, identifying key genetic changes that cause damage in the lungs and a drug treatment that could speed up recovery. Tuberculosis (TB) is a lung infection that has killed…
Malaysia registers first hepatitis C treatment developed through South-South cooperation
New treatment combination for hepatitis C virus (HCV) is an additional affordable option for millions still waiting for access to lifesaving treatments in middle-income countries
Targeted drug found effective in thwarting pancreatic tumors
Pancreatic cancer is an aggressive disease in which malignant cells form in the tissues of the pancreas, a long and flat gland located behind the stomach that helps with digestion and blood sugar regulation. Because pancreatic cancer is difficult to…
ACTG launches phase 1 combination HIV cure study
Los Angeles, Calif. – The AIDS Clinical Trials Group (ACTG), the largest global HIV research network, today announced the launch of A5386, a phase 1 HIV cure study evaluating two promising therapies. A5386 will study whether N-803 (a clinical-stage biologic…
LIM domain only 1: One gene, many roles in cancer
Researchers detail another gene target that could be the crucial link to curing different cancers
First AI-based tool for predicting genomic subtypes of pancreatic cancer from histology slides
ASCO 2021 — More groundbreaking science from a fruitful AP-HP Greater Paris University Hospitals and Owkin collaboration
Low doses of “laughing gas” could be fast acting, highly effective treatment for severe depression
A new study at the University of Chicago Medicine and Washington University found that a single inhalation session with 25% nitrous oxide gas was nearly as effective as 50% nitrous oxide at rapidly relieving symptoms of treatment-resistant depression, with fewer adverse side effects.
NIH-funded study tests “one-stop” mobile clinics to deliver HIV, substance use care
NIH-funded study tests “one-stop” mobile clinics to deliver HIV, substance use care A clinical trial is underway in five U.S. cities to determine whether delivering integrated health services through mobile clinics can improve HIV and substance use outcomes among people…
Lower and safer doses of laughing gas relieve treatment-resistant depression in phase 2 trial
A single one-hour treatment with nitrous oxide – also known as laughing gas – can relieve symptoms of treatment-resistant depression for several weeks, according to a phase 2 clinical trial involving 28 participants. By showing that a 25% concentration of…
ACTG announces the addition of two monoclonal antibodies to ACTIV-2 outpatient treatment study for COVID-19
Los Angeles, Calif. – The AIDS Clinical Trials Group (ACTG), the largest global HIV research network, today announced the addition of two monoclonal antibodies, BMS-986414 and BMS-986413, to the COVID-19 outpatient treatment study, ACTIV-2 Outpatient Monoclonal Antibodies and Other Therapies…
Low doses of “laughing gas” could be fast, effective treatment for severe depression
In a phase 2 clinical trial, researchers found a one-hour inhalation session with 25% nitrous oxide gas improved depression symptoms for over two weeks
Free event will connect heart, lung, blood and sleep point-of-care inventors with resources
M2D2 program to feature NIH, Johnson & Johnson leaders