In a clinical trial led by Yale Cancer Center (YCC) and Smilow Cancer Hospital, researchers aim to exploit DNA mutations in the treatment of two blood and bone marrow cancers, a different tacit than the more traditional approach of blunting or switching off genetic mutations linked to cancer
Tag: Cancer
Research sheds important light on the metastasis of neuroblastoma
The findings, published in British Journal of Cancer, were discovered by Professor Maria Kavallaris and her team could potentially lead to new treatment
Immunotherapy drug improves outcomes for some children with relapsed leukemia
New findings from a clinical trial show that treatment with the immunotherapy drug blinatumomab is superior to standard chemotherapy for children and young adults with high- or intermediate-risk B-cell acute lymphoblastic leukemia (B-ALL) that has relapsed. Those treated with blinatumomab…
AGA releases guideline on management of gastric intestinal metaplasia
Bethesda, MD (Dec. 6, 2019) — Gastric intestinal metaplasia (GIM), which is linked to non-cardia gastric cancer, is often detected during routine endoscopy, leading to questions about how patient care should be managed. A new clinical guideline1 from the American…
ASTRO issues new guideline on radiation therapy for basal, squamous cell skin cancers
Recommendations define how and when radiation therapy should be used to treat the most common types of skin cancer
Drug combination shows promise in preclinical models of triple negative breast cancer
Hollings Cancer Center researchers explore how to help the 60 percent of patients with TNBC who do not respond well to more traditional treatments
New Mayo Clinic studies to be presented at American Society of Hematology meeting
Mayo Clinic researchers will present findings at the American Society of Hematology Annual Meeting Dec. 7–10 in Orlando.
New Mayo Clinic studies to be presented include:
DNA analysis identifies elevated risk factor for myeloma in individuals of African ancestry
Study identifies more precise assessment measures for patients newly diagnosed with chronic lymphocytic leukemia
Researchers develop method to assess cancer-fighting cell therapy’s effectiveness
New software tool uses AI to help doctors identify cancer cells
UT Southwestern researchers have developed a software tool that uses artificial intelligence to recognize cancer cells from digital pathology images – giving clinicians a powerful way of predicting patient outcomes.
Yale Cancer Center study highlights challenges for care of AML patients during initial chemotherapy
A new study by Yale Cancer Center (YCC) researchers shows understanding treatment patterns for patients with acute myeloid leukemia (AML) is vital to develop strategies to improve outcomes.
Yale Cancer Center researchers show promising new treatment for patients with myelodysplastic syndromes
A new study by Yale Cancer Center (YCC) and Smilow Cancer Hospital researchers suggests that the drug venetoclax aids therapy for relapsed/refractory myelodysplastic syndromes, especially when paired with azacytidine.
UCLA study shows inhibition of gene helps overcome resistance to immunotherapy
A new study from scientists at UCLA helps explain why some people with advanced cancer may not respond to one of the leading immunotherapies, PD-1 blockade, and how a new combination approach may help overcome resistance to the immunotherapy drug.
Extending HPV vaccination ages would produce relatively small health benefits
Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine . The summaries are not intended to substitute for the full articles as a source of information. This information is…
New diagnostic methods to monitor blood disorders enabled by bio-rad’s droplet digital PCR technology showcased at 2019 Ash Annual Meeting
Orlando FL. – December 9, 2019 – Scientists will present more than 40 abstracts highlighting research driven in part by Bio-Rad Laboratories’ Droplet Digital PCR (ddPCR) technology at the 2019 American Society of Hematology (ASH) meeting in Orlando Florida, December…
Treatment with PD-1 prior to stem cell transplant is safe for Hodgkin lymphoma patients
Post-transplant treatment with cyclophosphamide reduces rates of acute GVHD and relapse
Scientists show thin metal mesh loaded with T cells shrinks solid tumors
Within weeks, CAR T cells targeting ovarian cancer cleared tumors in 70% of treated mice, shows study in Nature Biomedical Engineering (Note: Images available for media use)
Extending HPV vaccination ages would produce relatively small health benefits
Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine . The summaries are not intended to substitute for the full articles as a source of information. This information is…
New diagnostic methods to monitor blood disorders enabled by bio-rad’s droplet digital PCR technology showcased at 2019 Ash Annual Meeting
Orlando FL. – December 9, 2019 – Scientists will present more than 40 abstracts highlighting research driven in part by Bio-Rad Laboratories’ Droplet Digital PCR (ddPCR) technology at the 2019 American Society of Hematology (ASH) meeting in Orlando Florida, December…
Treatment with PD-1 prior to stem cell transplant is safe for Hodgkin lymphoma patients
Post-transplant treatment with cyclophosphamide reduces rates of acute GVHD and relapse
Scientists show thin metal mesh loaded with T cells shrinks solid tumors
Within weeks, CAR T cells targeting ovarian cancer cleared tumors in 70% of treated mice, shows study in Nature Biomedical Engineering (Note: Images available for media use)
Follicular lymphoma remission for 2+ years indicates disease-free status could be lifelong
Use of next-generation sequencing provides evidence of no detectable lymphoma in these patients
Genomic features of AML in patients over age 60 can predict success of stem cell transplant
Genomic profiles can be used to classify patients by risk of relapse after transplant
Use of venetoclax in transplant conditioning regimen shows promise in myeloid cancers
Trial is important step toward determining if this drug add-on can reduce risk of relapse in these patients
Yale Cancer Center researchers show identifying type of chronic pain in adults with sickle cell disease may lead to better outcomes
Identifying the type of pain an adult with sickle cell disease (SCD) experiences may be useful in improving treatment, according to a new study by researchers at Yale Cancer Center (YCC) and Smilow Cancer Hospital.
Acupuncture reduces radiation-induced dry mouth for cancer patients
Patients who had acupuncture during radiation reported less dry mouth symptoms up to 12 months after treatment
Improved pH probes may help towards cancer treatments
“It is becoming clear that an acid extracellular pH plays an essential role in cancer cell progression, invasiveness and resistance to therapy,” explain Yuri Korchev and Yasufumi Takahashi at Nano Life Science Institute of Kanazawa University and Yanjun Zhang at…
Guiding Lights: UC San Diego Launches Center for Fluorescence-Guided Surgery
UC San Diego launches new Center for Fluorescence-Guided Surgery. The center builds upon Roger Tsien’s legacy, delivering a new caliber of surgical precision to treat patients with tumors and disease of all types, identifying unhealthy tissues with a fluorescent glow.
Taming chronic inflammation may reduce illness, save lives
Scientists from 22 institutions, including UCLA, are recommending early diagnosis, prevention and treatment of severe chronic inflammation to reduce the risk of chronic disease and death worldwide.
Coriell Institute for Medical Research Scientist Receives Grant to Find Drivers of Breast Cancer
Shoghag Panjarian, PhD, a research scientist at the Coriell Institute for Medical Research, has been awarded a grant from the W. W. Smith Charitable Trust to support her search for epigenetic factors that contribute to the development and growth of breast cancer.
‘Virtual biopsy’ allows doctors to accurately diagnose precancerous pancreatic cysts
Research from doctors at The Ohio State University Wexner Medical Center finds a new “virtual biopsy” allows them to definitively diagnose cysts in the pancreas with unprecedented accuracy. This means they can eliminate precancerous cysts and potentially save lives. The…
Immune checkpoint therapy for ER+ breast cancers, a missed opportunity?
In the United States, apart from some forms of skin cancer, breast cancer is the most common cancer in women. It is also the most common cause of death from cancer among Hispanic women and the second most common among…
Detailed insight into stressed cells
Researchers at Goethe University develop new protoeomics procedure
Cancer treatment for patients with HIV
What The Study Did: For patients with HIV, CD4 counts reflect the health of their immune system and HIV RNA levels indicate their viral load. This observational study focused on how cancer treatments were associated with those two important clinical…
‘Virtual biopsy’ allows doctors to accurately diagnose precancerous pancreatic cysts
Research from doctors at The Ohio State University Wexner Medical Center finds a new “virtual biopsy” allows them to definitively diagnose cysts in the pancreas with unprecedented accuracy. This means they can eliminate precancerous cysts and potentially save lives. The…
‘Junk DNA’ affects inherited cancer risk
A person’s risk of developing cancer is affected by genetic variations in regions of DNA that don’t code for proteins, previously dismissed as ‘junk DNA’, according to new research published in the British Journal of Cancer today (Friday). This new…
Long-term study finds faster breast cancer radiation treatment as effective as long course
The treatment takes place in 1 week or less
Accelerated PBI not equivalent, but close, to WBI to control ipsilateral breast tumor recurrence
Accelerated partial breast irradiation although close was not equivalent to whole-breast irradiation to control ipsilateral breast tumor recurrence
Study finds wide county-level variation in rates of surgery for early-stage lung cancer
Socioeconomic and healthcare delivery factors appear to contribute to the gap
Immune checkpoint therapy for ER+ breast cancers, a missed opportunity?
In the United States, apart from some forms of skin cancer, breast cancer is the most common cancer in women. It is also the most common cause of death from cancer among Hispanic women and the second most common among…
Study finds wide county-level variation in rates of surgery for early-stage lung cancer
Socioeconomic and healthcare delivery factors appear to contribute to the gap
Detailed insight into stressed cells
Researchers at Goethe University develop new protoeomics procedure
Cancer treatment for patients with HIV
What The Study Did: For patients with HIV, CD4 counts reflect the health of their immune system and HIV RNA levels indicate their viral load. This observational study focused on how cancer treatments were associated with those two important clinical…
A Cancer Drug Trial For Dogs Presented At The RSNA Annual Meeting
What do you do when your best friend is diagnosed with a cancer that kills most of its patients within a few months? A few brave dog owners turned to Johns Hopkins, where veterinarians, radiologists and physicists have teamed up to conduct an experimental trial of a therapy they hope will extend the lives of their beloved pets.
STUDY FINDS ‘VIRTUAL BIOPSY’ ALLOWS DOCTORS TO ACCURATELY DIAGNOSE PRECANCEROUS PANCREATIC CYSTS
Research from doctors at The Ohio State University Wexner Medical Center finds a new “virtual biopsy” allows them to definitively diagnose cysts in the pancreas with unprecedented accuracy. This means they can eliminate precancerous cysts and potentially save lives.
The Medical Minute: Progress slow against pancreatic cancer
Researchers are still trying to find ways of catching pancreatic cancer early – or better yet, preventing it altogether. Meantime, here’s what patients need to know.
American Cancer Society and Flatiron Health launch real-world data impact award
Grant seeks to support patient-centric research through funding and access to real-world oncology dataset
Tel Aviv University’s Prof. Carmit Levy receives Young Investigator Award from SMR
Researcher honored for major contributions to the field of melanoma research
Common heart drugs linked with less heart damage from cancer therapy
Vienna, Austria – 4 December 2019: Cancer patients receiving common heart drugs have less heart damage from cancer therapy, according to research presented today at EuroEcho 2019, a scientific congress of the European Society of Cardiology (ESC).1 For every ten…
A big step toward curbing graft-vs.-host disease after bone marrow transplant
Abatacept, currently used for arthritis, gains FDA Breakthrough Therapy Designation for acute GVHD prevention
Targeted therapy better for repeat kidney cancer patients than FDA-approved counterpart
City of Hope co-led a phase 3 clinical trial that may soon change how renal cell carcinoma patients are treated in third- and fourth-line therapies
Stricter alcohol policies related to lower risk of cancer
New study finds stronger alcohol regulations may be promising means of reducing cancer deaths