Cancer patients own reporting of their quality of life can be important in predicting the outcome of their disease, say researchers from the European Organisation for Research and Treatment of Cancer (EORTC). Until recently, reports from clinicians on issues such…
Tag: Cancer
Researchers identify a process responsible for therapeutic resistance in breast cancer
Researchers at the Lady Davis Institute have identified a key protein that is required for resistance to chemotherapy in the most aggressive form of breast cancer.
Olaparib becomes first gene-targeted medicine to show benefits in prostate cancer
A pioneering precision medicine already licensed for breast and ovarian cancer can also slow or stop tumour growth in some men with advanced prostate cancer, a new clinical trial shows. The phase II trial found that over 80 per cent…
Researchers find common measures of immune status, inflammation can predict mortality
Newly published research led by Cleveland Clinic, University Hospitals
ESMO Immuno-Oncology Congress 2019
From the basics of immunotherapies to the latest research results
Researchers at IRB Barcelona study how altered protein degradation contributes to the development of tumors
To understand the molecular bases of cancer, it is imperative to determine the genetic alterations responsible for the development and spread of this condition and to identify the mechanisms through which healthy cells become malignant. In the last twenty years,…
Developing a new AI breast cancer diagnostic tool
Scientists are developing a new way to identify the unique chemical ‘fingerprints’ for different types of breast cancers.
New technique visually depicts how cancer cells grow and spread in colon tissue
Even before cancer is detectable, glow-in-the-dark cells show mutations driving malignancy
Study shows link between precipitation, climate zone and invasive cancer rates in the US
New Rochelle, NY, December 2, 2019–In a new study, researchers provide conclusive evidence of a statistical relationship between the incidence rates of invasive cancer in a given area in the U.S. and the amount of precipitation and climate type (which…
Novel MRI-guided ultrasound treatment destroys prostate cancer
CHICAGO – A novel MRI-guided procedure that uses therapeutic ultrasound effectively treats prostate cancer with minimal side effects, according to a new study presented today at the annual meeting of the Radiological Society of North America (RSNA). Researchers said the…
Decades old debate settled: Golgi key to maintenance of molecule-sorting station in cells
New mechanism to explain how the cell organelle that sorts and distributes substances entering a cell is formed and maintained
New treatment triggers self-destruction of pancreatic cancer cells
Research conducted on human pancreatic tumors transplanted in mice reveals promising results, Tel Aviv University researchers say
Researchers identify a process responsible for therapeutic resistance in breast cancer
Researchers at the Lady Davis Institute have identified a key protein that is required for resistance to chemotherapy in the most aggressive form of breast cancer.
Researchers find common measures of immune status, inflammation can predict mortality
Newly published research led by Cleveland Clinic, University Hospitals
New treatment for brain tumors uses electrospun fiber
Researchers with the University of Cincinnati used coaxial electrospinning to create a treatment for glioblastoma multiforme
ESMO Immuno-Oncology Congress 2019
From the basics of immunotherapies to the latest research results
Colorado study suggests new strategies against bone metastases from prostate cancer
When prostate cancer spreads, it most often spreads to bone. And while the 5-year survival rate for prostate cancer that has not spread is nearly 100 percent, once the disease reaches bone, the 5-year survival rate is only 29 percent.…
Researchers at IRB Barcelona study how altered protein degradation contributes to the development of tumors
To understand the molecular bases of cancer, it is imperative to determine the genetic alterations responsible for the development and spread of this condition and to identify the mechanisms through which healthy cells become malignant. In the last twenty years,…
Reflecting on photos helps young cancer survivors regain confidence
Retelling cancer story through photography increases self-esteem
New technique visually depicts how cancer cells grow and spread in colon tissue
Even before cancer is detectable, glow-in-the-dark cells show mutations driving malignancy
Decades old debate settled: Golgi key to maintenance of molecule-sorting station in cells
New mechanism to explain how the cell organelle that sorts and distributes substances entering a cell is formed and maintained
Novel MRI-guided ultrasound treatment destroys prostate cancer
CHICAGO – A novel MRI-guided procedure that uses therapeutic ultrasound effectively treats prostate cancer with minimal side effects, according to a new study presented today at the annual meeting of the Radiological Society of North America (RSNA). Researchers said the…
New treatment for brain tumors uses electrospun fiber
Researchers with the University of Cincinnati used coaxial electrospinning to create a treatment for glioblastoma multiforme
Developing a new AI breast cancer diagnostic tool
Scientists are developing a new way to identify the unique chemical ‘fingerprints’ for different types of breast cancers.
Colorado study suggests new strategies against bone metastases from prostate cancer
When prostate cancer spreads, it most often spreads to bone. And while the 5-year survival rate for prostate cancer that has not spread is nearly 100 percent, once the disease reaches bone, the 5-year survival rate is only 29 percent.…
Researchers identify protein that governs human blood stem cell self-renewal
UCLA scientists have discovered a link between a protein and the ability of human blood stem cells to self-renew. In a study published today in the journal Nature, the team reports that activating the protein causes blood stem cells to self-renew at least twelvefold in laboratory conditions
Zantac Recalled for Carcinogen Levels Above FDA Standards
The popular heartburn drug ranitidine, commonly known as Zantac, was voluntarily recalled due to the contamination of a human carcinogen that could potentially cause cancer. The recall includes oral tablets, capsules, and syrup.
Inadequacies in current early-stage lung cancer treatment revealed
Researchers from Tohoku University and Tohoku University Hospital have revealed why some existing cancer treatments are ineffective in tackling the early-stages of lung cancer. A team led by Professor Tetsuya Kodama investigated the ability of anti-cancer agents to affect early-stage…
What protects killer immune cells from harming themselves?
White blood cells, which release a toxic potion of proteins to kill cancerous and virus-infected cells, are protected from any harm by the physical properties of their cell envelopes, find scientists from UCL and the Peter MacCallum Cancer Centre in…
Linking wound healing and cancer risk
When our skin is damaged, a whole set of biological processes springs into action to heal the wound. Now, researchers from the VIB-UGent Center for Inflammation Research have shown that one of the molecules involved in this, HMGB1, slows down…
Research: Alcohol and tobacco policies can reduce cancer deaths
Policies aimed at cutting alcohol and tobacco consumption, including the introduction of random breath testing programs and bans on cigarette advertising, have resulted in a significant reduction in Australian cancer death rates, new research shows. The La Trobe Centre for…
Cancer research that’s out-of-this-world
Australia’s first space research mission to the International Space Station will attempt to establish how some of the most aggressive cancer cells behave in a zero-gravity environment
Biennial mammography screening yields more advanced-stage cancers
CHICAGO – Cancers found in patients undergoing annual mammography screening are smaller and less advanced than those found in patients undergoing screenings every two years, according to a new study presented next week at the annual meeting of the Radiological…
A novel pathway to target colorectal cancer
Investigators at the Medical University of South Carolina report in Gastroenterology that PGE2, a signaling molecule involved in inflammation, promotes colorectal cancer progression
UK and China research team take first steps towards a vaccine for pancreatic cancer
Researchers from Queen Mary University of London and Zhengzhou University have developed a personalised vaccine system that could ultimately delay the onset of pancreatic cancer. The study provides strong proof-of-concept for the creation of a vaccine for cancer prevention in…
Biennial mammography screening yields more advanced-stage cancers
CHICAGO – Cancers found in patients undergoing annual mammography screening are smaller and less advanced than those found in patients undergoing screenings every two years, according to a new study presented next week at the annual meeting of the Radiological…
Splicing factor to blame in triple negative breast cancer
A splicing factor called TRA2B enhances triple negative breast cancers’ ability to grow and metastasize.
Linking wound healing and cancer risk
When our skin is damaged, a whole set of biological processes springs into action to heal the wound. Now, researchers from the VIB-UGent Center for Inflammation Research have shown that one of the molecules involved in this, HMGB1, slows down…
A novel pathway to target colorectal cancer
Investigators at the Medical University of South Carolina report in Gastroenterology that PGE2, a signaling molecule involved in inflammation, promotes colorectal cancer progression
UK and China research team take first steps towards a vaccine for pancreatic cancer
Researchers from Queen Mary University of London and Zhengzhou University have developed a personalised vaccine system that could ultimately delay the onset of pancreatic cancer. The study provides strong proof-of-concept for the creation of a vaccine for cancer prevention in…
Splicing factor to blame in triple negative breast cancer
A splicing factor called TRA2B enhances triple negative breast cancers’ ability to grow and metastasize.
Intestinal Stem Cell Genes May Link Dietary Fat and Colon Cancer
Two genes that appear to help stem cells in the intestine burn dietary fat may play a role in colon cancer, according to a Rutgers study. The study, published in the journal Gastroenterology, describes a new connection between the way cells consume fat and how genes regulate stem cell behavior in the intestines of mice.
Safety evaluation of conditionally immortalized cells for renal replacement therapy
Here, the research team assessed the safety of conditionally immortalized proximal tubule epithelial cells for bioartificial kidney application, by using in vitro assays and athymic nude rats
Prostate cancer: radiation therapy effective in patients with no further treatment options
Reports of new cancer treatments often raise high hopes and expectations, particularly, of course, among cancer patients and their families. But raising expectations is not something that Samer Ezziddin, Professor of Nuclear Medicine and Director of the Department of Nuclear…
High expression of apoptosis protein (Api-5) in chemoresistant triple-negative breast cancers: an innovative target
The cover for issue 61 of Oncotarget features Figure 4, ‘The influence of stress conditions on API-5 expression and inhibition,’ by Bousquet, et al.
Using gene scissors to detect diseases
The CRISPR/Cas technology can do more than alter genes. A research team at the University of Freiburg is using what are known as gene scissors – which scientists can use to edit genetic material – in order to better diagnose…
Recovering from metabolic syndrome significantly reduces risk for cardiovascular disease
Embargoed News from Annals of Internal Medicine
Konstanz-based CRC 969 to receive additional funding
The Konstanz-based research in the area of cellular proteostasis will receive funding in the amount of approximately EUR ten million for another four years, at the end of which it will have reached its maximum funding period of twelve years.…
Cellular origins of pediatric brain tumors identified
Researchers make a breakthrough by identifying that several aggressive pediatric brain tumors are the result of stalled development in embryonic cells
New approach to treating incurable leukemia in children discovered
Acute lymphoblastic leukemia (ALL) is a form of blood cancer that primarily affects children and young people. It involves large quantities of malignant progenitor cells building up in a person’s blood instead of healthy white blood cells. This is often…