A small clinical trial shows promising results for patients with triple-negative breast cancer who received an investigational vaccine designed to prevent recurrence of tumors. Conducted at Washington University School of Medicine in St. Louis with a therapy designed by WashU Medicine researchers, the trial is the first to report results for this type of vaccine — known as a neoantigen DNA vaccine — for breast cancer patients.
Tag: Cancer Vaccine
Cleveland Clinic Announces Updated Findings in Preventive Breast Cancer Vaccine Study
Cleveland Clinic researchers are presenting updated findings from their novel study of a vaccine aimed at preventing triple-negative breast cancer, the most aggressive and lethal form of the disease.
The study team found that the investigational vaccine was generally well tolerated and produced an immune response in most patients. The team described the side effects of the vaccine, showed the highest tolerated dose to date, and presented the immunologic effects of the vaccine. Findings are being presented at the Society for Immunotherapy of Cancer Annual Meeting.
An AI-powered pipeline for personalized cancer vaccines
Ludwig Cancer Research scientists have developed a full, start-to-finish computational pipeline that integrates multiple molecular and genetic analyses of tumors and the specific molecular targets of T cells and harnesses artificial intelligence algorithms to use its output to design personalized cancer vaccines for patients.
Study Shows Cancer Vaccine Blocks Tumor Progression at Early Lesion Stage
A cancer vaccine that had little success in clinical trials for patients with advanced tumors could potentially have efficacy if administered earlier in the treatment cycle, according to a study from Vanderbilt researchers.
PhotonPharma to Present at Rocky Mountain Life Sciences Investor and Partnering Conference
PhotonPharma, a pioneering biotech company focused on innovative cancer therapies, is pleased to announce its selection as a premier presenting company in the upcoming Rocky Mountain Life Sciences Investor and Partnering Conference sponsored by the Colorado BioScience Association.
Maui attorney turns brain cancer journey into hope for others
Newirth beat the odds thanks to a novel cancer vaccine developed by UCLA neurosurgeon Linda Liau, MD, PhD. And now, he’s doing everything in his power to support cutting-edge cancer research and provide extra support to individuals going through cancer treatment.
Get Ready for ASCO 2024 Annual Meeting
ASCO, the largest event in cancer research, is approaching on May 31st. This year’s meeting promises to be particularly groundbreaking, with new findings and innovations that could revolutionize cancer treatment.
Adding immune-boosting agent to personalized cancer vaccine supercharges the body’s immune defense against malignant brain tumors
Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have pinpointed a combination immunotherapy treatment that enhances the immune response for people with malignant gliomas, an aggressive type of brain tumor that is fast growing and difficult to treat.
MD Anderson and CureVac enter strategic collaboration to develop novel cancer vaccines
MD Anderson and CureVac today announced a co-development and licensing agreement to develop novel mRNA-based cancer vaccines.
Nanoparticle vaccine could curb cancer metastasis to lungs by targeting a protein
UC San Diego engineers have developed an experimental vaccine that could prevent the spread of metastatic cancers to the lungs. Its success lies in targeting a protein known to play a central role in cancer growth and spread, rather than targeting the primary tumor itself.
LJI scientists harness ‘helper’ T cells to treat tumors
La Jolla Institute for Immunology (LJI) scientists have published a pair of studies that show how we might harness CD4+ T cells while boosting the cancer-fighting power of CD8+ “killer” T cells.
Chula Excellence Cancer Center collabs with medical specialists from various fields to enhance treatment capabilities.
Chula now has an Excellence Chulalongkorn Comprehensive Cancer Center bringing together medical specialists from various areas of expertise to attend to cancer patients using the latest academic and technological know-how to enhance the quality of life and the possibilities of being cured for patients of all types of cancer.
New nanotechology design provides hope for personalized vaccination for treating cancer
A new study demonstrates the use of charged nanoscale metal-organic frameworks for generating free radicals using X-rays within tumor tissue to kill cancer cells. The same frameworks can be used for delivering immune signaling molecules to activate the immune response against tumor cells.
Small Change makes Cancer Vaccine More Effective in Animal Tests
Tweaking the adenovirus spike protein induces a more robust immune reaction for a cancer vaccine against gastric, pancreatic, esophageal and colon malignancies in animal models.