Machine Learning Leads to Novel Way to Track Tremor Severity in Parkinson’s Patients

Physical exams only provide a snapshot of a Parkinson’s patient’s daily tremor experience. Scientists have developed algorithms that, combined with wearable sensors, can continuously monitor patients and estimate total Parkinsonian tremor as they perform a variety of free body movements in their natural settings. This new method holds great potential for providing a full spectrum of patients’ tremors and medication response, providing clinicians with key information to effectively manage and treat their patients with this disorder.

Novel agent flips on garbage disposal in neurons, eliminating toxic brain proteins in mice

CHICAGO — Neuroscientists at Georgetown University Medical Center say they have developed and tested an agent that reduces the buildup of toxic proteins in animal models of both Parkinson’s and Alzheimer’s diseases, and improves cognitive and motor behavior. The team…

Overcoming the blood-brain-barrier: Delivering therapeutics to the brain

For the first time, scientists have identified a simple way that can effectively transport medication into the brain – which could lead to improved treatments for neurological and neurodegenerative diseases. In a study published today in Nature Communications , scientists…

Experts call for coordinated action to avert a brain disease crisis

Experts are calling for a public health campaign aimed at promoting a ‘brain-healthy lifestyle’ to reduce the risk of developing neurodegenerative brain diseases, such as Alzheimer’s disease and Parkinson’s disease. The campaign should support existing health promotion work by emphasising…

VCU will lead $50 million study of traumatic brain injuries in military personnel

Virginia Commonwealth University has been awarded a $50 million federal grant to oversee a national research consortium of universities, hospitals and clinics that will study the long-term impacts of mild traumatic brain injuries or concussions on service members and veterans.…

Researchers find regulator of first responder cells to brain injury

Astrocytes are the most abundant cells in the brain, yet there is still much to learn about them. For instance, it is known that when the brain is injured or diseased astrocytes are the first responders. They become reactive and…

New proteomics technique gives insights into ubiquitin signalling

Australian researchers are among the first in the world to have access to a new approach to understand intricate changes that control how proteins function in our cells in health and disease. The new proteomics technique called ‘ubiquitin clipping’ allows…