This study, called a systematic review and meta-analysis, combined the results of seven studies with 4.3 million participants to examine a potential association between bipolar disorder with a later diagnosis of Parkinson disease of unknown cause. The findings suggest that a previous diagnosis of bipolar disorder was associated with increased likelihood of a subsequent Parkinson disease diagnosis but subgroup analyses suggest the possibility of an overestimation of the magnitude of the associations. The main limitation of the study is analysis that suggests a greater likelihood of a Parkinson disease diagnosis in shorter studies which raises concerns over misdiagnosis.
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Joaquim J. Ferreira, M.D., Ph.D., Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal, and coauthors.
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This part of information is sourced from https://www.eurekalert.org/pub_releases/2019-10/jn-ibd101019.php
Joaquim J. Ferreira, M.D., Ph.D.