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UrduCell membrane protrusions called blebs that typically signify the end of life for healthy cells do the opposite for melanoma cells, activating processes in these cells that help them to survive and spread, a UT Southwestern study suggests.
Tag: Ut Southwestern
Business consultant and investor Debra Hunter Johnson named Chair of UT Southwestern President’s Advisory Board
Business consultant, attorney, and investor Debra Hunter Johnson, founder of Reciprocity Consulting Group, will chair the UT Southwestern Medical Center President’s Advisory Board for the 2023-2025 term.
Autoantibody linked to rare disorder that destroys fat, UT Southwestern researchers find
Researchers at UT Southwestern Medical Center have discovered the first molecular biomarker for acquired generalized lipodystrophy (AGL), a rare disorder in which fat deposits are destroyed, causing patients to have dangerously low body fat, signs of accelerated aging, and severe metabolic diseases including diabetes and fatty liver.
Young pregnant adolescents at increased risk of preeclampsia, C-section, UTSW study shows
Young adolescents face different challenges in pregnancy compared with their older teenage peers and adults that are sometimes exacerbated by high rates of obesity, a new study by UT Southwestern researchers suggests. The findings, published in the American Journal of Obstetrics & Gynecology MFM, could highlight at-risk populations for targeted prevention efforts.
All that texting and scrolling leads to a rise in ‘tech neck’
Technology can be a pain in the neck, leading to what’s known as “tech neck,” chronic pain that results from prolonged use of mobile phones, tablets, and other electronic devices.
Potential genetic regulators of the heartbeat identified by UT Southwestern researchers
UT Southwestern Medical Center researchers have mapped gene control elements in specialized cardiac cells responsible for coordinating heartbeats. The findings of the genome exploration study, published in The Journal of Clinical Investigation, provide insight into how heartbeats are regulated and could impact diagnosis and risk prediction for a variety of common arrhythmias.
Screening teens for vaping history key to diagnosing lung disease during pandemic
The severity of a lung disease associated with e-cigarettes in teens decreased during the COVID-19 pandemic, but hospitalizations from the disease continued to mount, according to a study of more than three dozen patients by UT Southwestern researchers published in Pediatric Pulmonology.
UT Southwestern researchers discover gene regulation mechanism
UT Southwestern Medical Center researchers have discovered a method cells use to turn genes on and off that involves portions of proteins whose function has long been a mystery. The findings, reported in Cell, could lead to new ways of controlling gene regulation and may one day lead to new treatments for a broad array of diseases.
Head trauma doesn’t predict memory problems in NFL retirees, UT Southwestern study shows
A study of retired professional football players by researchers at UT Southwestern Medical Center found that their cognitive abilities did not differ significantly from a control group of similarly aged men who did not play football, nor did those abilities show significant change over one to five years. The findings were published in Brain Injury.
UT Southwestern researchers identify risk factors for unsuccessful bunion surgery
A study by UT Southwestern researchers has identified three factors that increase the risk that bunion surgery will fail to fix this painful foot condition. The findings, published in The Journal of Foot and Ankle Surgery, provide information that surgeons can use to counsel patients considering this elective procedure.
Liver cancer treatment costly for Medicare patients, UT Southwestern study finds
Hepatocellular carcinoma (HCC), the most common type of liver cancer, can place a significant financial burden on patients, according to an analysis led by a researcher at UT Southwestern Medical Center.
UT Southwestern cardiologist receives NIH Outstanding Investigator Award
UT Southwestern physician-scientist Hesham Sadek, M.D., Ph.D., has received the prestigious National Institutes of Health (NIH) Outstanding Investigator Award to support his ongoing research into mechanisms behind heart regeneration that could lead to treatments for heart failure.
UT Southwestern biochemist, molecular biologist to receive HHMI Emerging Pathogens awards
Two of UT Southwestern’s Howard Hughes Medical Institute researchers in biochemistry and molecular biology will lead separate teams as part of HHMI’s Emerging Pathogens Initiative (EPI) targeting infectious diseases that pose a threat to human health.
UT Southwestern ophthalmologist shares techniques for cataract surgery complications
Patients undergoing cataract surgery typically have their natural lens replaced with an artificial intraocular lens (IOL). But complications occasionally arise that require the placement of a more surgically challenging secondary IOL. Several techniques are available for secondary IOL placement, and each has its advantages and disadvantages.
Gene editing halts damage in mice after heart attacks in UT Southwestern study
Editing a gene that prompts a cascade of damage after a heart attack appeared to reverse this inevitable course in mice, leaving their hearts remarkably unharmed, a new study by UT Southwestern scientists showed. The findings, published in Science, could lead to a new strategy for protecting patients from the consequences of heart disease.
UTSW-led study shows promise for drug to treat upper urinary tract cancers
A team from 15 U.S. medical centers led by UT Southwestern Simmons Cancer Center researchers has performed the first analysis of a potentially game-changing drug to treat upper urinary tract urothelial cancers.
UT Southwestern rheumatologist recommends patients receive pneumococcal vaccine
Patients with rheumatoid arthritis, lupus, and other rheumatic conditions are more at risk for complications and death from pneumonia, meningitis, and other bacterial infections, yet most have not been vaccinated against infection.
New technique from UTSW improves high-intensity focused ultrasound treatment for brain disorders
UT Southwestern physicians have developed an improved targeting method, four-tract tractography, to personalize MRI-guided, high-intensity focused ultrasound (HIFU) used at UTSW to treat medication refractory tremor in essential tremor and tremor-dominant Parkinson’s disease.
UT Southwestern immunologists uncover obesity-linked trigger to severe form of liver disease
UT Southwestern immunologists have uncovered a key pathogenic event prompted by obesity that can trigger severe forms of nonalcoholic fatty liver disease and potential liver failure.
Mortality rates are higher in U.S. counties with more evictions, UTSW researchers find
Mortality rates are higher in U.S. counties where eviction rates are also elevated, and this trend is strongest in areas with higher proportions of Black residents and women, UT Southwestern researchers found.
Gene therapy corrects mutation responsible for common heart condition, UT Southwestern research shows
Using the CRISPR-Cas9 gene editing system, UT Southwestern researchers corrected mutations responsible for a common inherited heart condition called dilated cardiomyopathy (DCM) in human cells and a mouse model of the disease.
New drug combination offers hope for improved treatment of cervical cancer
A new combination of drugs slowed the growth of cancer cells by an unexpected mechanism that may one day lead to improved treatment of cervical cancer, a UT Southwestern-led study published in Molecular Cancer Research suggests.
UTSW expanding mental health program for teens throughout Texas
UT Southwestern Medical Center is expanding an evidence-based mental health promotion and crisis prevention program for adolescents to schools across Texas after receiving $11.5 million in funding from the state.
Researchers discover rare form of premature-aging syndrome
UT Southwestern researchers have discovered a new form of progeria, a rare premature-aging syndrome, in a man from Malaysia and traced its cause to a novel gene mutation.
Singers’ genre may play role in voice injuries
A singer’s primary genre can impact the likelihood of developing vocal fold injury and may even influence the specific type of injury that occurs, a recent study by UT Southwestern researchers suggests.
Flu shots are recommended for those 65 and older as cases rise
With flu cases on the rise, geriatric specialists at UT Southwestern Medical Center say vaccinations are particularly important this year for people 65 and older who are more at risk from complications than other age groups.
COVID-19 vaccine’s effectiveness diminishes with age, research shows
The Pfizer-BioNTech COVID-19 vaccine limits transmission, hospitalization, and death from COVID-19 even among patients infected by variants of the virus, but the effectiveness of antibodies it generates diminishes as patients get older, according to a study by UT Southwestern researchers.
Financial assistance programs improve outcomes for indigent patients with inflammatory bowel disease
Patients with inflammatory bowel diseases (IBD) who required treatment and were enrolled in a financial assistance program were less likely to need surgery after starting medication than those not enrolled in a program, a study by UT Southwestern researchers found.