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UrduBiomedical scientists at KU Leuven have discovered that a defect in the ATP13A2 gene causes cell death by disrupting the cellular transport of polyamines. When this happens in the part of the brain that controls body movement, it can lead…
Tag: genes
Gene hunting: The power of precision medicine
MU researchers improve animal welfare by discovering genetic mutations that cause disease
ASHG survey finds Americans strongly support human genetics research and potential
Respondents want confidence in data privacy, have some knowledge gaps
Organoids (in vitro brains) to study pediatric brain tumors
A large-scale production of in vitro tumors could make it possible to perform large drug screenings to identify new brain cancer drugs
Brain tumors remodel neuronal synapses to promote growth
Scientists at Baylor College of Medicine have found new evidence that glioma, a lethal form of brain cancer, alters the activity of neighboring neurons, accelerating a vicious cycle that drives tumor-associated epilepsy and tumor progression. Their findings, published in Nature…
ASHG survey finds Americans strongly support human genetics research and potential
Respondents want confidence in data privacy, have some knowledge gaps
Organoids (in vitro brains) to study pediatric brain tumors
A large-scale production of in vitro tumors could make it possible to perform large drug screenings to identify new brain cancer drugs
Brain tumors remodel neuronal synapses to promote growth
Scientists at Baylor College of Medicine have found new evidence that glioma, a lethal form of brain cancer, alters the activity of neighboring neurons, accelerating a vicious cycle that drives tumor-associated epilepsy and tumor progression. Their findings, published in Nature…
Tiny salamander’s huge genome may harbor the secrets of regeneration
The type of salamander called axolotl, with its frilly gills and widely spaced eyes, looks like an alien and has other-worldly powers of regeneration. Lose a limb, part of the heart or even a large portion of its brain? No problem: They grow back.
Major Asian Gene Study to Help Doctors Battle Disease
“Under-representation of Asian populations in genetic studies has meant that medical relevance for more than half of the human population is reduced,” one researcher said.
Scientists create listeriosis-immune mice by turning off gene in myeloid cells
The study provides exciting material for understanding the mechanisms of the immune response to pathogenic microorganisms.
Towards better anti-cancer drugs
New insights into CDK8, an important human oncogene
Scientists short-circuit maturity in insects, opening new paths to disease prevention
Puberty-controlling hormone does not travel freely into the brain as previously thought
Major Asia gene study to help doctors battle disease
An ambitious new study of genes in Asian populations is filling in big gaps in our understanding of human genetics, shedding light on the history of human migration and ultimately aiming to improve our ability to treat disease. Researchers from…
Gene therapy success in chronic septic granulomatosis
Rare disease of the immune system
Scientists create listeriosis-immune mice by turning off gene in myeloid cells
The study provides exciting material for understanding the mechanisms of the immune response to pathogenic microorganisms.
Towards better anti-cancer drugs
New insights into CDK8, an important human oncogene
Major Asia gene study to help doctors battle disease
An ambitious new study of genes in Asian populations is filling in big gaps in our understanding of human genetics, shedding light on the history of human migration and ultimately aiming to improve our ability to treat disease. Researchers from…
Give & take: Cancer chromosomes give the game away
Cancer chromosome arms’ gains and losses give new insight into treatment and outcome of different cancers
Scientists short-circuit maturity in insects, opening new paths to disease prevention
Puberty-controlling hormone does not travel freely into the brain as previously thought
Gene therapy success in chronic septic granulomatosis
Rare disease of the immune system
Genomics experts dispute nine genes linked to congenital heart condition
NHGRI-funded ClinGen panel also validates three genes believed to be associated with long QT syndrome
Protein AKAP8 suppresses breast cancer metastasis
A protein naturally produced in the body has been found to suppress breast cancer metastasis in animal models of human tumors. Researchers led by Baylor College of Medicine also found that high levels of this protein, AKAP8, predicts a better…
New bacteriophage fully characterized and sequenced
New Rochelle, NY, January 27, 2020–Researchers have identified a new bacteriophage that can infect and destroy bacteria in the genus Pantoea, for which few bacteriophage have been identified and characterized. Details of the isolation, characterization, and full genome sequencing of…
Genomics experts dispute nine genes linked to congenital heart condition
NHGRI-funded ClinGen panel also validates three genes believed to be associated with long QT syndrome
Hundreds of UCLA students publish encyclopedia of 1,000 genes linked to organ development
A team of 245 UCLA undergraduates and 31 high school students has published an encyclopedia of more than 1,000 genes, including 421 genes whose functions were previously unknown. The research was conducted in fruit flies, and the genes the researchers…
Protein AKAP8 suppresses breast cancer metastasis
A protein naturally produced in the body has been found to suppress breast cancer metastasis in animal models of human tumors. Researchers led by Baylor College of Medicine also found that high levels of this protein, AKAP8, predicts a better…
New bacteriophage fully characterized and sequenced
New Rochelle, NY, January 27, 2020–Researchers have identified a new bacteriophage that can infect and destroy bacteria in the genus Pantoea, for which few bacteriophage have been identified and characterized. Details of the isolation, characterization, and full genome sequencing of…
Hundreds of UCLA students publish encyclopedia of 1,000 genes linked to organ development
A team of 245 UCLA undergraduates and 31 high school students has published an encyclopedia of more than 1,000 genes, including 421 genes whose functions were previously unknown. The research was conducted in fruit flies, and the genes the researchers…
Russian expert is ready to comment on the coronavirus
Pavel Volchkov heads the Genome Engineering Lab at the Moscow Institute of Physics and Technology (MIPT), that has several key projects, all of them involving genome editing mediated by the CRISPR/Cas technology. Discovered just a few years ago, CRISPR/Cas has…
Liver Fibrosis “Off Switch” Discovered in Mice
UC San Diego School of Medicine researchers identified several genetic switches, or transcription factors, that determine whether or not liver cells produce collagen — providing a new therapeutic target for liver fibrosis.
Unravelling arthropod genomic diversity over 500 million years of evolution
An international team of scientists report in the journal Genome Biology results from a pilot project, co-led by Robert Waterhouse, Group Leader at the SIB Swiss Institute of Bioinformatics and University of Lausanne, to kick-start the global sequencing initiative of…
Largest autism genetics study identifies 102 genes associated with the condition
In the largest genetic sequencing study of autism spectrum disorder (ASD) to date, researchers have identified 102 genes associated with risk for autism. The study also shows significant progress towards teasing apart the genes associated with ASD from those associated…
‘To safeguard people from chemical pollution, another approach is warranted’
We live in an increasingly complex world when it comes to chemicals. The number of new chemicals has increased from 20 million in 2002 to 156 million last year. Many of these are ubiquitous in the world around us because…
Revealed an alteration related to the loss of effectiveness of a treatment in lung cancer
The Cancer Genetics Group of the Josep Carreras Leukaemia Research Institute, led by Montse Sánchez-Céspedes, together with Luis Montuenga from CIMA, and Enriqueta Felip from Vall d’Hebron Hospital, has revealed that inactivation of RB1 through intragenic rearrangements is frequent in…
Scanning system in sperm may control rate of human evolution
Maturing sperm cells turn on most of their genes, not to follow their genetic instructions like normal, but instead to repair DNA before passing it to the next generation, a new study finds. Led by NYU Grossman School of Medicine…
Unravelling arthropod genomic diversity over 500 million years of evolution
An international team of scientists report in the journal Genome Biology results from a pilot project, co-led by Robert Waterhouse, Group Leader at the SIB Swiss Institute of Bioinformatics and University of Lausanne, to kick-start the global sequencing initiative of…
Largest autism genetics study identifies 102 genes associated with the condition
In the largest genetic sequencing study of autism spectrum disorder (ASD) to date, researchers have identified 102 genes associated with risk for autism. The study also shows significant progress towards teasing apart the genes associated with ASD from those associated…
‘To safeguard people from chemical pollution, another approach is warranted’
We live in an increasingly complex world when it comes to chemicals. The number of new chemicals has increased from 20 million in 2002 to 156 million last year. Many of these are ubiquitous in the world around us because…
Revealed an alteration related to the loss of effectiveness of a treatment in lung cancer
The Cancer Genetics Group of the Josep Carreras Leukaemia Research Institute, led by Montse Sánchez-Céspedes, together with Luis Montuenga from CIMA, and Enriqueta Felip from Vall d’Hebron Hospital, has revealed that inactivation of RB1 through intragenic rearrangements is frequent in…
Scanning system in sperm may control rate of human evolution
Maturing sperm cells turn on most of their genes, not to follow their genetic instructions like normal, but instead to repair DNA before passing it to the next generation, a new study finds. Led by NYU Grossman School of Medicine…
Surprise discovery shakes up our understanding of gene expression
A group of University of Chicago scientists has uncovered a previously unknown way that our genes are made into reality. Rather than directions going one-way from DNA to RNA to proteins, the latest study shows that RNA itself modulates how DNA is transcribed—using a chemical process that is increasingly apparent to be vital to biology. The discovery has significant implications for our understanding of human disease and drug design.
Life’s Frankenstein beginnings
New evidence shows the first building blocks of life on Earth may have been messier than previously thought
Life’s Frankenstein beginnings
New evidence shows the first building blocks of life on Earth may have been messier than previously thought
Scientists identify gene that puts brakes on tissue growth
Findings in worm with regenerative prowess could aid human tissue engineering methods
Scientists identify gene that puts brakes on tissue growth
Findings in worm with regenerative prowess could aid human tissue engineering methods
Autoimmunity may explain why an important immune system is absent in many bacteria
New findings from University of Exeter researchers reveal how bacterial immune systems can be harmful for their hosts and explain why they are not found in many bacteria. CRISPR-Cas is an immune system that protects bacteria against infection by viruses…
Autoimmunity may explain why an important immune system is absent in many bacteria
New findings from University of Exeter researchers reveal how bacterial immune systems can be harmful for their hosts and explain why they are not found in many bacteria. CRISPR-Cas is an immune system that protects bacteria against infection by viruses…
Genetic identification of human remains from the Spanish Civil War and the dictatorship
A research team at the UPV/EHU is working to optimise genetic analyses for identifying victims who disappeared during the Spanish Civil War and the subsequent dictatorship
Genetic identification of human remains from the Spanish Civil War and the dictatorship
A research team at the UPV/EHU is working to optimise genetic analyses for identifying victims who disappeared during the Spanish Civil War and the subsequent dictatorship