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UrduLight-controlled genes could reveal how gut bacteria impact health
Tag: Gastroenterology
Visible hydrogels for rapid hemorrhage control and monitoring
(LOS ANGELES) – There are many different events which may lead to excessive and uncontrolled bleeding within the body. This can occur as a result of inflammation and ulcerations, abnormalities in the blood vessels or trauma-related injuries. Individuals with predisposing…
Potential preventative treatment demonstrated for Crohn’s disease
This potential preventive treatment for Crohn’s disease was tested on a mouse model and on immune-reactive T cells from patients with Crohn’s disease.
Join us virtually: 2021 Crohn’s & Colitis Congress®
Dec. 18, 2020 — The Crohn’s & Colitis Congress®, the premier conference for inflammatory bowel disease (IBD) health care providers and researchers, invites media to register for the virtual 2021 meeting experience. A partnership of the Crohn’s & Colitis Foundation…
Patients don’t receive recommended follow-up care after weight loss surgery
Peer reviewed – observational study – humans
The American College of Gastroenterology Issues Its First Clinical Guideline on Management of Irritable Bowel Syndrome
The new guideline recommends is a positive diagnostic strategy involving a careful history, physical examination, and limited diagnostic testing, which can substantially shorten time to appropriate therapy and be more cost-effective for patients.
A comprehensive review of early-onset colorectal SEER data is the first to specifically assess adeno
Embargoed news from Annals of Internal Medicine
Compound derived from thunder god vine could help pancreatic cancer patients
TGen-led study indicates drug attacks ‘super-enhancers’ in the DNA of cancer cells and in the stromal cocoon that hides the tumor from the immune system
Beta-blockers display anti-inflammatory effects in advanced liver disease
Beneficial effects on systemic inflammation translate into improved clinical outcomes
Four ERC Consolidator Grants for KU Leuven researchers
The European Research Council (ERC) has awarded its Consolidator Grants. Four KU Leuven researchers are among this year’s recipients in Belgium: breast cancer researcher Christine Desmedt, computer scientist Tias Guns, chemical engineer Simon Kuhn, and psychiatrist Lukas Van Oudenhove. ERC…
UBCO researchers suggest stool transplants can battle serious infections
Genetic analysis helps ensure successful fecal microbiota transplants
New treatment in development for irritable bowel syndrome with constipation
Preclinical study finds that an innovative bilayered capsule can overcome current challenges for delivering drugs to the colon; findings suggest new solution for relieving abdominal pain associated with IBS-C
Disrupting the cellular process that promotes pancreatic cancer’s deadly growth
WASHINGTON (December 8, 2020) — Researchers say they’ve identified a way to disrupt a process that promotes the growth of pancreatic cancers — one of the most difficult and deadly cancers to treat. The team, led by scientists at Georgetown…
December Issue of The American Journal of Gastroenterology Highlights Health Disparities and Social Determinants of Health
The December issue of The American Journal of Gastroenterology is now available and features new clinical research across a wide range of gastroenterology and hepatology topics, including health disparities, colorectal cancer, cirrhosis, pediatric gastroenterology, the environmental impact of endoscopy, and more.
New fundamental knowledge of the ‘abdominal brain’
Researchers at Karolinska Institutet have succeeded in mapping the neuron types comprising the enteric nervous system in the intestine of mice. The study, which is published today in the scientific journal Nature Neuroscience , also describes how the different neurons…
Gut research identifies key cellular changes associated with childhood-onset Crohn’s Disease
Scientists have tracked the very early stages of human foetal gut development in incredible detail, and found specific cell functions that appear to be reactivated in the gut of children with Crohn’s Disease. The results are an important step towards…
Synthetic biology and machine learning speed the creation of lab-grown livers
PITTSBURGH, Dec. 7, 2020 – Researchers at the University of Pittsburgh School of Medicine have combined synthetic biology with a machine-learning algorithm to create human liver organoids with blood- and bile-handling systems. When implanted into mice with failing livers, the…
Study identifies links between atopic dermatitis and autoimmune diseases
In a recent study published in the British Journal of Dermatology , individuals with atopic dermatitis, or eczema, were more likely to also have various autoimmune diseases, especially those involving the skin, the gastrointestinal tract, or the connective tissue. For…
Pediatric appendix perforation rate at children’s hospital during COVID-19 pandemic
What The Study Did: This observational study assessed the rate of appendix perforations during the COVID-19 pandemic at a children’s hospital compared with 2019. Authors: Rick Place, M.D., M.H.A., of Inova Fairfax Medical Campus in Falls Church, Virginia, is the corresponding author. To…
Gut microbiome snapshot could reveal chemical exposures in children
Study of how semi-volatile organic compounds affect bacteria and fungi reveals new relationships and bacteria used for bioremediation in children’s guts
New butterfly-inspired hydrogen sensor is powered by light
Light-activated sensor delivers precision results at room temperature
Major depressive disorder may be defined by a distinct gut microbiome
Landscapes of bacterial and metabolic signatures and their interaction in major depressive disorders
How rotavirus causes severe gastrointestinal disease
Rotavirus is a major cause of diarrhea and vomiting, especially in children, that results in approximately 128,000 deaths annually. The virus triggers the disease by infecting enterocyte cells in the small intestine, but only a fraction of the susceptible cells…
University of Miami Health System Gastroenterologist Honored with ‘Lifetime Disruptor’ Award
Maria T. Abreu, M.D., a renowned gastroenterologist at the University of Miami Miller School of Medicine, was honored with the “Lifetime Disruptor” award at the American College of Gastroenterology’s 2020 virtual meeting.
Gut microbiome manipulation could result from virus discovery
Rutgers co-authored research could aid efforts to engineer beneficial bacteria
Normothermic Machine Perfusion (NMP) in rat livers extended from 6 to 24 hours
In a paper published in TECHNOLOGY , a team of researchers from Massachusetts General Hospital (MGH) have demonstrated 24-hour rat liver viability in a normothermic machine perfusion (NMP) system. Rat liver perfusion is an efficient and cost-effective method to study…
Randomized trial of laparoscopic, open liver surgery found no difference in long-term survival ou
Embargoed news from Annals of Internal Medicine
Study pinpoints target for managing inflammation, promoting tissue repair
Cincinnati Children’s team reports controlling the BCAP protein could slow overactive immune response in IBD, rheumatoid arthritis or accelerate response against tumors
Managing the microbiome raises new hope for autism
According to the Centers for Disease Research, 1 in 54 children is diagnosed with autism spectrum disorder (ASD) each year, and the number has been rising. The disease causes perplexing, lifelong developmental disabilities, which usually arise during early childhood and…
Expert alert: Changing the outlook for pancreatic cancer
Pancreatic cancer often is hidden and doesn’t cause symptoms until it has spread. It is a leading cause of cancer deaths in the world.
November 19 is World Pancreatic Cancer Day, but the entire month of November is meant to bring awareness to this disease.
Advances in screening and early detection for high-risk people, minimally invasive surgical innovations and new genetic classifications are changing the outlook for pancreatic cancer, says Dr. Michael Wallace, a Mayo Clinic gastroenterologist.
Innovative double-balloon catheter awarded Canadian patent
SealCath LLC, a Medical University of South Carolina startup, wins Canadian patent for its double-balloon catheter.
Aviara Pharmaceuticals, Inc receives grant to collaborate with the Texas Heart Institute
Texas Collaboration to Develop Treatment for Inflammatory Disease
People with inflammatory bowel disease still die earlier despite increase in life
A study comparing life expectancy of people with inflammatory bowel disease (IBD) and without found that, while life expectancy increased for both groups, people with IBD generally died sooner. The study is published in CMAJ (Canadian Medical Association Journal) .…
Experts release new management strategies for malignant colorectal polyps
Bethesda, Maryland (Nov. 4, 2020) – Early identification and removal of cancerous colorectal polyps is critical to preventing the progression of colorectal cancer and improving survival rates. The U.S. Multisociety Task Force on Colorectal Cancer has released new guidance for…
Combining Eastern medicine with Western to improve cancer therapy
Can ancient Chinese herbs cure chemotherapy-related diarrhea?
Exploring the role of gut microbiota in pediatric celiac disease
Mathers Foundation grant will support work of Boston College biologist Emrah Altindis
Johns Hopkins Researchers engineer tiny machines that deliver medicine efficiently
“Theragrippers” are inspired by a parasitic worm that clamps onto its host’s intestines
Nerves keep pancreatic cancer cells from starving
Pancreatic cancer cells avert starvation by signaling to nerves, which grow into dense tumors and secrete nutrients. This is the finding of a study with experiments in cancer cells, mice, and human tissue samples published online November 2 in Cell…
Diet quality, survival among individuals with metastatic colorectal cancer
What The Study Did: Whether quality of diet was associated with overall survival among patients beginning treatment for metastatic colorectal cancer was examined in this study. Authors: Erin Van Blarigan, Sc.D., of the University of California in San Francisco, is…
CHOP genomic study reveals role for hypothalamus in inflammatory bowel disease
Integrating 3D genomics with publicly available, genome-wide genetic data, researchers uncovered genetic correlations between IBD, stress, and depression
How the immune system deals with the gut’s plethora of microbes
The gut is an unusually noisy place, where hundreds of species of bacteria live alongside whatever microbes happen to have hitched a ride in on your lunch. Scientists have long suspected that the gut’s immune system, in the face of…
U.S. News & World Report: UC San Diego #1 for Gastroenterology and Hepatology Research
U.S. News & World Report named University of California San Diego School of Medicine a top global university and ranked the divisions of Gastroenterology and Hepatology #1 in the world for research.
Microbial strains show individualized patterns of stability in the developing infant gut
This study used powerful genomic tools and supercomputers to analyze massive amounts of genetic data and identify individual strains within single species of the gut microbiome present during an infant’s first 6 years of life
A new paradigm in patient care
Mechanical engineering assistant professor Elliot Hawkes is one of 20 Packard Fellows for 2020
New Clinical Advances in Gastroenterology Presented at the American College of Gastroenterology’s 85th Annual Scientific Meeting
More than 7,000 gastroenterologists and other health care professionals so far will convene virtually for the premier clinical gastroenterology event—the American College of Gastroenterology’s 85th Annual Scientific Meeting and Postgraduate Course (Virtual ACG 2020)—to review the latest scientific advances in gastrointestinal research, treatment of digestive diseases, and clinical practice management.
American College of Gastroenterology Announces Winners of Sixth Annual SCOPYs: Service Award for Colorectal Cancer Outreach, Prevention, and Year-Round Excellence
The American College of Gastroenterology (ACG) announces the winners of the 2020 SCOPY Awards (Service Award for Colorectal Cancer Outreach, Prevention, and Year-Round Excellence) to recognize the achievements of ACG members in their community engagement, education and awareness efforts for colorectal cancer prevention.
Changes in hospital volumes for common medical emergencies during COVID-19
What The Study Did: Whether the number of cases at hospitals of common medical emergencies such as heart attack and appendicitis have changed during the COVID-19 pandemic was investigated in this study. Authors: Melanie Hayden Gephart, M.D., M.A.S., of the…
Inhibitor of KRAS gene mutation shows promise in lung, bowel and other solid tumors
Latest results from KRYSTAL-1 early clinical trial of adagrasib (MRTX849)
Next generation BRAF inhibitor cancer drug shows promise in early patient trial
A new drug designed to work on cancers with an altered BRAF gene has shown promise in an early patient trial presented at the 32nd EORTC-NCI-AACR [1] Symposium on Molecular Targets and Cancer Therapeutics, which is taking place online. The…
Achieving high concentrations of sunitinib in tumors is linked to improved survival
Intermittent high dosing regimen for patients with advanced cancers is safe and results in very high concentrations of the drug in the tumor