Radioactive bone cement found to be safer in treating spinal tumors

Irvine, Calif., Feb. 16, 2021 — A radioactive bone cement that’s injected into bone to provide support and local irradiation is proving to be a safer alternative to conventional radiation therapy for bone tumors, according to a study led by University of California, Irvine researchers. The study shows that this brachytherapy cement can be placed into spinal bones to directly irradiate tumors without harming the spinal cord, and the radioactive material will stay localized in the bones, which promises to virtually eliminate side effects.

Lipid epoxides target pain, inflammatory pathways in neurons

CHAMPAIGN, Ill. — When modified using a process known as epoxidation, two naturally occurring lipids are converted into potent agents that target multiple cannabinoid receptors in neurons, interrupting pathways that promote pain and inflammation, researchers report. These modified compounds, called…

Kessler Foundation awarded three grants for spinal cord injury research studies

Craig H. Neilsen Foundation ensures ongoing support for studies delayed by effects of pandemic. Funding provided for research addressing environmental barriers, chronic pain and racial disparities that affect individuals with spinal cord injury

Opioid prescriptions remained elevated two years after critical care

Nearly 11 percent of people admitted to an intensive care unit in Sweden between 2010 and 2018 received opioid prescriptions on a regular basis for at least six months and up to two years after discharge. That is according to…

Nutrition, companionship reduce pain in mice with sickle cell disease, UCI-led study finds

Irvine, Calif., Feb. 1, 2021 — Researchers from the University of California, Irvine and the University of Minnesota have found that an enriched diet and companionship can reduce pain in mice with sickle cell disease by increasing serotonin. They also discovered that duloxetine, an antidepressant that boosts serotonin levels, could be an alternative to opioids in treating chronic pain.

Immersive virtual reality boosts the effectiveness of spinal cord stimulation for chronic pain

For patients receiving spinal cord stimulation (SCS) for chronic pain, integration with an immersive virtual reality (VR) system – allowing patients to see as well as feel the effects of electrical stimulation on a virtual image of their own body – can enhance the pain-relieving effectiveness of SCS, reports a study in PAIN®, the official publication of the International Association for the Study of Pain (IASP). The journal is published in the Lippincott portfolio by Wolters Kluwer.

LOOP technique for I&D of abscesses in adults is safe, effective alternative to I&D with packing

DES PLAINES, IL — The LOOP technique for incision and drainage (I&D) of abscesses in adults is a safe and effective alternative to the traditional I & D with packing and may offer an alternative to the standard regimen in…

Promising treatment for premenstrual dysphoric disorder, PMDD

The mental symptoms of premenstrual dysphoric disorder improve following treatment with a progesterone receptor modulator, as demonstrated by SciLifeLab researcher Erika Comasco and Professor Inger Sundström-Poromaa, Uppsala University. The mechanism of action of the study drug provides insights into the…