In an analysis of nationwide data from the Veterans Health Administration, approximately one-quarter of individuals with kidney stones had a diagnosis of osteoporosis or bone fracture around the time of their kidney stone diagnosis. The findings are published in the…
Tag: pain
New study gives the most detailed look yet at the neuroscience of placebo effects
A large proportion of the benefit that a person gets from taking a real drug or receiving a treatment to alleviate pain is due to an individual’s mindset, not to the drug itself. Understanding the neural mechanisms driving this placebo…
The conditions of 70% of people with chronic pain have worsened during the pandemic
The typical profile of participants in this study was that of a woman aged between 30 and 59 who had been suffering pain for the last seven years
NYU Oral Cancer Center awarded NIH grant to study interplay between oral cancer and nerves
Research to investigate sensitization and activation of “capsaicin receptor” on pain-sensing nerves by cancer mediators, and how these nerves promote cancer progression
Addressing a complex world of pain in a single gene difference
A single letter difference in a single gene, inherited from both parents, spells a lifetime of anemia and pain for 20 million people, mostly of African ancestry, worldwide. Sickle cell disease (SCD) causes red blood cells to assume a sickle…
Research agreement focuses on battlefield injuries
WEST LAFAYETTE, Ind. – OYE Therapeutics Inc., a Purdue University-affiliated company, is working to reduce the mortality and morbidity resulting from injuries on the battlefield through the development of new life-saving strategies. OYE is located in the Purdue Technology Center…
Study shows opioid use among US patients with knee osteoarthritis costs 14 billion dollars in societal costs
Although guidelines do not recommend use of opioids to manage pain for individuals with knee osteoarthritis, a recent study published early online in Arthritis Care & Research , an official journal of the American College of Rheumatology and the Association…
Treating rheumatoid arthritis with micromotors
Rheumatoid arthritis is a chronic inflammatory disorder marked by joint pain, swelling and damage. Although medications, such as steroids, anti-inflammatory drugs and immunosuppressants, can help slow joint destruction and relieve pain, they have side effects and aren’t completely successful. Now,…
Study finds digital treatment for osteoarthritis is superior to traditional routine care
Joint Academy’s online treatment effectively addresses growing and costly chronic disease safely during the global pandemic
Center for Psychedelic Medicine established at NYU Langone Health
New program builds on notable achievements and offers first-ever dedicated training program for early career investigators
Microneedle patches for microdosing psychedelic pharmaceuticals
(LOS ANGELES) – Although one may think of psychedelic pharmaceuticals as being dangerous and detrimental, scientists have been conducting experiments and clinical trials on some of them and have obtained positive results when testing them for medical use. Research has…
TBE patients’ lasting problems
Impaired memory, reduced motivation, and declining motor skills. These are some of the problems that may persist several years after people contract tick-borne encephalitis, a University of Gothenburg thesis shows. Tick-borne encephalitis (TBE) is caused by a virus, found in…
Good sleep is just what doctor ordered
In a study released Feb. 22 in JAMA Internal Medicine researchers found that six 20-minute telephone calls over eight weeks coaching participants on how to get better sleep improved their sleep, pain, and daytime function. The improvements in sleep and daytime function persisted 12 months after treatment. One of the lead investigators who has been researching age and sleeping for 40 years offers great tips on getting better sleep. Just because you are aging, does NOT mean your sleep needs to get worse.
A fifth of adults in Sweden report dental anxiety
In Sweden, approximately one in five adults suffers from dental anxiety or phobia. The number has decreased over time, but still an important part of the population have major problems, according to a recent doctoral thesis from the University of…
Yale scientists repair injured spinal cord using patients’ own stem cells
Intravenous injection of bone marrow derived stem cells (MSCs) in patients with spinal cord injuries led to significant improvement in motor functions, researchers from Yale University and Japan report Feb. 18 in the Journal of Clinical Neurology and Neurosurgery .…
Certain factors are linked with an elevated risk of bone fractures
A new study published in the Journal of Bone and Mineral Research has identified various factors that may indicate whether a person faces a higher likelihood of experiencing a bone fracture over the next two decades. The study included 30,446…
Physical conditions linked to psychological distress in patients with cancer
Among patients with cancer, having additional physical comorbidities was linked with a higher risk of experiencing psychological distress. The finding comes from a Psycho-Oncology analysis of 2017 data from the National Health Survey of Spain. The analysis included 484 patients…
Radiological images confirm ‘COVID-19 can cause the body to attack itself’
Imaging illustrates severity, long-term prognosis of COVID-19-related muscle, joint pain
High patient uptake for text message system monitoring opioid use in real-time
After more than 1,000 orthopaedic procedures at a city health system, roughly 61 percent of the opioids prescribed to patients went unused, according to new research. This was discovered within a study at the Perelman School of Medicine of the…
Radioactive bone cement found to be safer in treating spinal tumors
Irvine, Calif., Feb. 16, 2021 — A radioactive bone cement that’s injected into bone to provide support and local irradiation is proving to be a safer alternative to conventional radiation therapy for bone tumors, according to a study led by University of California, Irvine researchers. The study shows that this brachytherapy cement can be placed into spinal bones to directly irradiate tumors without harming the spinal cord, and the radioactive material will stay localized in the bones, which promises to virtually eliminate side effects.
New research identifies biological causes of muscle weakness in later life
A new largescale genetic analysis has found biological mechanisms that contribute to making people more susceptible to muscle weakness in later life, finding that diseases such as osteoarthritis and diabetes may play a large role in susceptibility. As we get…
Lundquist Institute receives $1.75 million grant from Steven & Alexandra Cohen Foundation
The grant will fund clinical trials to study the efficacy of psilocybin in treating the emotional suffering associated with terminal medical illness
Lipid epoxides target pain, inflammatory pathways in neurons
CHAMPAIGN, Ill. — When modified using a process known as epoxidation, two naturally occurring lipids are converted into potent agents that target multiple cannabinoid receptors in neurons, interrupting pathways that promote pain and inflammation, researchers report. These modified compounds, called…
Notes of discomfort: Study keys in on trends in marching band members’ pain
CORVALLIS, Ore. – Marching band members in leadership roles are more likely to feel discomfort in the neck and upper back than their less experienced bandmates, who in turn are more susceptible to left-hand pain and cognitive strain, a new…
Kessler Foundation awarded three grants for spinal cord injury research studies
Craig H. Neilsen Foundation ensures ongoing support for studies delayed by effects of pandemic. Funding provided for research addressing environmental barriers, chronic pain and racial disparities that affect individuals with spinal cord injury
Solving chronic pain during intercourse
Researchers at Flinders University are working to remedy this situation by identifying what triggers this chronic pain in the female reproductive tract. Dr Joel Castro Kraftchenko – Head of Endometriosis Research for the Visceral Pain Group (VIPER), with the College…
How does pain experienced in everyday life impact memory?
A new study indicates that brain systems related to emotional distress could underlie the negative impacts of pain on memory in healthy individuals.
Opioid prescriptions remained elevated two years after critical care
Nearly 11 percent of people admitted to an intensive care unit in Sweden between 2010 and 2018 received opioid prescriptions on a regular basis for at least six months and up to two years after discharge. That is according to…
Modeling the brain during pain processing
Novel approaches in graph theory have enabled researchers to reveal the characteristic configurations of neurons which arise as our brains process pain
Remyelinating drug could improve vision in patients with multiple sclerosis
UC Riverside-led mouse study stresses MS treatment should be started early
Nutrition, companionship reduce pain in mice with sickle cell disease, UCI-led study finds
Irvine, Calif., Feb. 1, 2021 — Researchers from the University of California, Irvine and the University of Minnesota have found that an enriched diet and companionship can reduce pain in mice with sickle cell disease by increasing serotonin. They also discovered that duloxetine, an antidepressant that boosts serotonin levels, could be an alternative to opioids in treating chronic pain.
Nutrition, companionship reduce pain in mice with sickle cell disease, UCI-led study finds
Serotonin-boosting antidepressant duloxetine had same effect, could be opioid alternative
New realm of personalized medicine with brain stimulation
Researchers’ “skeleton key” can unlock a brain
Enhanced Recovery Efforts for Cesarean Delivery Reduce Need for Opioids by 80%
Results of study by Children’s Hospital Colorado show a third of patients not needing narcotic pain pills after c-section
New treatment helps patients with a spinal cord injury
Spinal cord injuries disrupt the mechanism by which our bodies regulate blood pressure; a team of Swiss and Canadian scientists have developed a treatment that allows patients to regain control of their blood pressure
NYU Dentistry awarded NIH grant to investigate oral cancer pain treatment utilizing co-delivery of DNA and RNA
Clinician-scientists Seiichi Yamano and Brian Schmidt to further novel gene therapy strategy to treat oral cancer pain
David Julius and Ardem Patapoutian win the Frontiers of Knowledge Award in Biomedicine
The two researchers have been recognized by the BBVA Foundation for discovering the receptors that mediate the sensations of temperature, pressure, and pain
Controlling pain after surgery doesn’t have to mean opioids, study shows
Comparison of opioid-sparing approach with standard care shows no difference in patient satisfaction, but less pain among those counseled to use opioids only as backup
Pain patients who take opioids can’t get in the door at over half of primary care clinics
‘Secret shopper’ study in 9 states finds stigma is highest against patients who say their last doctor stopped prescribing opioids to them
Impact of patient-reported symptom information on lumbar spine MRI Interpretation
Patient-reported symptom information from a brief questionnaire can be correlated with MRI findings to distinguish presumptive pain generators from incidental abnormalities
3-D printed Biomesh minimizes hernia repair complications
Hernias are one of the most common soft tissue injuries. Hernias form when intra-abdominal content, such as a loop of the intestine, squeezes through weak, defective or injured areas of the abdominal wall. The condition may develop serious complications, therefore…
Modified pain management strategy reduces opioid exposure to trauma patients, study shows
A pain management regimen comprised mostly of over-the-counter medication reduced opioid exposure in trauma patients while achieving equal levels of pain control, according to a new study by physician-researchers at UTHealth.
Pain-relief regimen treats trauma patients with fewer opioid drugs
Even with severe injuries, patients received affordable, generic medications to control pain while undergoing treatment and at discharge from a trauma center
New technique to fast-track pain research
Pioneering sensory neuron replication
Comparing reactions of flu vaccines in older adults
What The Study Did: Researchers in this randomized clinical trial compared injection-site pain and other reactions among adults age 65 and older who received flu vaccines. Author: Kenneth E. Schmader, M.D., of the Duke University School of Medicine in Durham,…
January/February 2021 Annals of Family Medicine tip sheet
Crowdsourced Responses from Dermatologists on Twitter Found to be as Effective as Formal Telemedicine At the start of the pandemic, many doctors on the front lines turned to Twitter and other social media platforms to find guidance and solace directly…
Treatment for chronic pain must address both physical and social pain
Physical pain and social pain may be more closely related than previously thought. Social pain, which typically results from interpersonal rejection or abuse, has been viewed as a non-medical response to external factors. However, recent research suggests that some physical…
ACP releases comprehensive framework to address disparities and discrimination in health care
Embargoed News from Annals of Internal Medicine
Post-surgical patch releases non-opioid painkiller directly to the wound
New polymer promises localized pain control for critical first four days
Despite recommendations, patients with treatment-resistant hypertension rarely tested for primary al
Embargoed News from Annals of Internal Medicine