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UrduThe neurodegenerative disease is marked by an expansion of DNA triplet repeats; the Tufts researchers pinpoint a mechanism for potentially reversing the expansion
Tag: genes
Severity of autism symptoms varies greatly among identical twins
Findings from NIH-funded study could inform treatment strategies
Here’s how public dissemination of biology is going wrong
Living things are too complex to be explained in terms of any single factor
Targeted screening could prevent one in six prostate cancer deaths
Nearly one in six deaths from prostate cancer could be prevented if targeted screening was introduced for men at a higher genetic risk of the disease, according to a new UCL-led computer modelling study
SHAPEIT4: An algorithm for large-scale genomic analysis
Researchers from UNIL, UNIGE and SIB provide the researchers’ community with an extremely powerful computer tool to facilitate the interpretation of the genome’s big data
Targeted screening could prevent one in six prostate cancer deaths
Nearly one in six deaths from prostate cancer could be prevented if targeted screening was introduced for men at a higher genetic risk of the disease, according to a new UCL-led computer modelling study
SHAPEIT4: An algorithm for large-scale genomic analysis
Researchers from UNIL, UNIGE and SIB provide the researchers’ community with an extremely powerful computer tool to facilitate the interpretation of the genome’s big data
Your DNA is not your destiny — or a good predictor of your health
New study from the University of Alberta suggests that diseases such as many cancers, diabetes, and Alzheimer’s have a genetic contribution of 5 to 10 per cent at most
Gene drives work faster than non-drive approaches to control problem insects
Mosquitoes engineered to spread genes that stop malaria are efficient, but mutations can arise
Your DNA is not your destiny — or a good predictor of your health
New study from the University of Alberta suggests that diseases such as many cancers, diabetes, and Alzheimer’s have a genetic contribution of 5 to 10 per cent at most
Mining metagenomics: A faster and more efficient method to compare metagenomes
Microbiomes can contain thousands of bacteria species, hinting at the complex ecosystem that houses the microbiome as well as the one contained within the microbiome. Yet, until now, researchers have been limited in the tools they have to precisely compare…
MAGIC system allows researchers to modulate the activity of genes acting in concert
Genomic research has unlocked the capability to edit the genomes of living cells; yet so far, the effects of such changes must be examined in isolation. In contrast, the complex traits that are of interest in both fundamental and applied…
Impact of methamphetamine use depends on your genes
Genetic clues which could explain why some people have more severe side effects from long-term methamphetamine use than others
Mining metagenomics: A faster and more efficient method to compare metagenomes
Microbiomes can contain thousands of bacteria species, hinting at the complex ecosystem that houses the microbiome as well as the one contained within the microbiome. Yet, until now, researchers have been limited in the tools they have to precisely compare…
MAGIC system allows researchers to modulate the activity of genes acting in concert
Genomic research has unlocked the capability to edit the genomes of living cells; yet so far, the effects of such changes must be examined in isolation. In contrast, the complex traits that are of interest in both fundamental and applied…
Impact of methamphetamine use depends on your genes
Genetic clues which could explain why some people have more severe side effects from long-term methamphetamine use than others
Gene drives work faster than non-drive approaches to control problem insects
Mosquitoes engineered to spread genes that stop malaria are efficient, but mutations can arise
OU study uses genetics and menthol to examine how the skin senses irritation
NORMAN, OKLA. – A new University of Oklahoma study could have implications on our understanding of how certain sensory signals are transmitted through the body. An OU experiment led by neuroscientist Christian Lemon, Ph.D., Department of Biology, set out to…
OU study uses genetics and menthol to examine how the skin senses irritation
NORMAN, OKLA. – A new University of Oklahoma study could have implications on our understanding of how certain sensory signals are transmitted through the body. An OU experiment led by neuroscientist Christian Lemon, Ph.D., Department of Biology, set out to…
Ancient ‘chewing gum’ yields insights into people and bacteria of the past
Researchers from the University of Copenhagen have succeeded in extracting a complete human genome from a thousands-of-years old “chewing gum”. According to the researchers, it is a new untapped source of ancient DNA. During excavations on Lolland, archaeologists have found…
Shifting the balance of growth vs. defense boosts crop yield
Cold Spring Harbor Laboratory (CSHL) scientists are figuring out how to pack more kernels onto a corn cob. One way to boost the productivity of a plant, they say, is to redirect some of its resources away from maintaining an…
Novel genetic signature that can predict some kinds of breast cancer is identified
The research, published in the journal PLOS Genetics, combined a study of the genes involved in retinopathy, as a model of angiogenesis, with analysis of transcriptomic gene expression profiles from public breast cancer databases.
Researchers create functional mini-liver by 3D bioprinting
Technique developed at Human Genome and Stem Cell Research Center, funded by FAPESP and hosted by the University of São Paulo, produced hepatic tissue in the laboratory in only 90 days and could become an alternative to organ transplantation in future
Ancient ‘chewing gum’ yields insights into people and bacteria of the past
Researchers from the University of Copenhagen have succeeded in extracting a complete human genome from a thousands-of-years old “chewing gum”. According to the researchers, it is a new untapped source of ancient DNA. During excavations on Lolland, archaeologists have found…
Can good sleep patterns offset genetic susceptibility to heart disease and stroke?
For the first time researchers have assessed the impact on the risk of heart or blood vessel problems from the combination of sleep patterns and genetic susceptibility to cardiovascular disease. The study, which is published in the European Heart Journal…
Genetic test could aid quest to reveal causes of rare diseases
The causes of rare diseases could be uncovered using an approach created to identify genetic mutations that trigger a muscle-wasting condition, a study suggests. Researchers have devised a way to pinpoint defective genes that are linked to a rare form…
Shifting the balance of growth vs. defense boosts crop yield
Cold Spring Harbor Laboratory (CSHL) scientists are figuring out how to pack more kernels onto a corn cob. One way to boost the productivity of a plant, they say, is to redirect some of its resources away from maintaining an…
Novel genetic signature that can predict some kinds of breast cancer is identified
The research, published in the journal PLOS Genetics, combined a study of the genes involved in retinopathy, as a model of angiogenesis, with analysis of transcriptomic gene expression profiles from public breast cancer databases.
Researchers create functional mini-liver by 3D bioprinting
Technique developed at Human Genome and Stem Cell Research Center, funded by FAPESP and hosted by the University of São Paulo, produced hepatic tissue in the laboratory in only 90 days and could become an alternative to organ transplantation in future
How mysterious circular DNA causes cancer in children
First map of circular DNA in childhood cancer
How mysterious circular DNA causes cancer in children
First map of circular DNA in childhood cancer
Research brief: New methods promise to speed up development of new plant varieties
A University of Minnesota research team recently developed new methods that will make it significantly faster to produce gene-edited plants. They hope to alleviate a long-standing bottleneck in gene editing and, in the process, make it easier and faster to…
Turning to genetics to treat little hearts
A team of researchers at CHU Sainte-Justine and Université de Montréal has discovered a new mechanism involved in a common congenital disease of the aortic valve. The findings of the study, conducted in collaboration with the Hadassa Hebrew University Medical…
Research brief: New methods promise to speed up development of new plant varieties
A University of Minnesota research team recently developed new methods that will make it significantly faster to produce gene-edited plants. They hope to alleviate a long-standing bottleneck in gene editing and, in the process, make it easier and faster to…
Turning to genetics to treat little hearts
A team of researchers at CHU Sainte-Justine and Université de Montréal has discovered a new mechanism involved in a common congenital disease of the aortic valve. The findings of the study, conducted in collaboration with the Hadassa Hebrew University Medical…
IU School of Medicine team learns how to predict triple negative breast cancer recurrence
Discovery marks progress in IU Precision Health Initiative Grand Challenge
IU School of Medicine team learns how to predict triple negative breast cancer recurrence
Discovery marks progress in IU Precision Health Initiative Grand Challenge
Largest study of its kind reveals that many psychiatric disorders arise from common genes
BOSTON – Many distinct psychiatric diseases share a common genetic structure, according to new research by scientists at Massachusetts General Hospital (MGH) and the Psychiatric Genomics Consortium, an international team of investigators. Psychiatric disorders affect more than 25 percent of…
New drugs more likely to be approved if backed up by genetics
New analysis confirms human genomic data could predict success in clinical trials
Largest study of its kind reveals that many psychiatric disorders arise from common genes
BOSTON – Many distinct psychiatric diseases share a common genetic structure, according to new research by scientists at Massachusetts General Hospital (MGH) and the Psychiatric Genomics Consortium, an international team of investigators. Psychiatric disorders affect more than 25 percent of…
New drugs more likely to be approved if backed up by genetics
New analysis confirms human genomic data could predict success in clinical trials
Teams of microbes are at work in our bodies. Here’s how to figure out what they’re doing
Drexel researchers’ algorithm toolkit can identify microbe communities and their functions
Your genes aren’t the only factor dictating Alzheimer’s risk, says Baycrest-U of T study
The colour of our eyes or the straightness of our hair is linked to our DNA, but the development of Alzheimer’s disease isn’t exclusively linked to genetics, suggest recently published findings.
Single-cell analysis of the earliest cell fate decisions in development
Multi-omics analysis of the process establishing the mammalian body plan
Modifier Gene May Explain Why Some with Cystic Fibrosis are Less Prone to Infection
People with cystic fibrosis who carry genetic variants that lower RNF5 gene expression have more mutant CFTR protein on cell surfaces. Even if the CFTR protein isn’t fully functional, it’s better than none, and may explain why some with cystic fibrosis are less prone to infection than others.
Genetic Breakthrough Identifies Heart Failure Risk in African and Latino Americans
Findings may inform genetic screening test for patients at risk and medically under-served
LSU Health discovers role of 2 proteins in sight and preventing blinding eye diseases
New Orleans, LA – Research led by Nicolas Bazan, MD, Ph.D., Boyd Professor and Director of the Neuroscience Center of Excellence at LSU Health New Orleans School of Medicine, has discovered unique patterns of genetic activity that may lead to…
Scientists accidentally discover a new water mold threatening Christmas trees
Grown as Christmas trees, Fraser firs are highly prized for their rich color and pleasant scent as well as their ability to hold their needles. Unfortunately, they are also highly susceptible to devastating root rot diseases caused by water molds…
Increasing food intake by swapping mitochondrial genomes
Many of the characteristics that make people so different from each other, are often the result of small differences in the DNA between individuals. Variation in just a single base in our DNA can cause significant variation in traits like…
Scientists accidentally discover a new water mold threatening Christmas trees
Grown as Christmas trees, Fraser firs are highly prized for their rich color and pleasant scent as well as their ability to hold their needles. Unfortunately, they are also highly susceptible to devastating root rot diseases caused by water molds…