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UrduIn a first-of-its-kind study published in the American Journal of Respiratory and Critical Care Medicine, physician-scientists from the University of Alabama at Birmingham Marnix E. Heersink School of Medicine discovered that high-dose inhaled nitric oxide therapy may improve oxygenation and reduce the risk of mortality among critically ill Black patients with COVID-19.
Tag: ARDS
AACN Practice Alert Offers Guidance on Manual Prone Positioning for Patients With ARDS
A newly released practice alert from the American Association of Critical-Care Nurses aims to standardize how nurses care for patients undergoing prone positioning therapy for extended periods of time. It summarizes expected nursing practice to reduce the risk of complications related to manual prone positioning.
High-Dose Anticoagulation Can Reduce Intubations and Improve Survival for Hospitalized COVID-19 Patients
High-dose anticoagulation can reduce deaths by 30 percent and intubations by 25 percent in hospitalized COVID-19 patients who are not critically ill when compared to the standard treatment, which is low-dose anticoagulation.
Early Mobility Improved Survival Rates for COVID-19 Patients Receiving ECMO
Baylor Scott & White The Heart Hospital, Plano, Texas, changed its treatment paradigm for its COVID-19 patients receiving ECMO during the pandemic, finding that progressive mobility and a more aggressive application of rehabilitation therapies contributed to significantly higher survival rates.
Extracellular Vesicles in Lung Fluid May Point to Acute Respiratory Distress Syndrome Severity
Article title: CD14-positive extracellular vesicles in bronchoalveolar lavage fluid as a new biomarker of acute respiratory distress syndrome Authors: Rahul Y. Mahida, Joshua Price, Sebastian T. Lugg, Hui Li, Dhruv Parekh, Aaron Scott, Paul Harrison, Michael A. Matthay, David R.…
COVID-19 Pulmonary, ARDS and Ventilator Resources Now Available in Spanish
A joint effort between the American Association of Critical-Care Nurses and projects funded by the U.S. Agency for International Development has made AACN’s free “COVID-19 Pulmonary, ARDS and Ventilator Resources” online course available in Spanish.
Recursos sobre COVID-19, SDRA y Ventilación Ahora disponible en español
Un esfuerzo conjunto entre la Asociación Americana de Enfermeras de Cuidados Críticos (AACN) y los proyectos financiados por la Agencia de los Estados Unidos para el Desarrollo Internacional (USAID) ha hecho posible que el curso en línea gratuito de la AACN “Recursos sobre COVID-19, SDRA y Ventilación” esté disponible en español.
Growing Use of Mechanical Circulatory Support Affects Clinician Well-Being, Moral Distress
The growing use of mechanical circulatory support may contribute to high levels of moral distress for clinicians who regularly care for ICU patients receiving the aggressive but life-sustaining therapy, according to a study by researchers at Columbia University Irving Medical Center.
Delivery for hospitalized pregnant women improves recovery outcome, study finds
Pregnant women hospitalized with COVID-19 had improved recovery outcomes after delivering their babies early, according to new research from The University of Texas Health Science Center at Houston (UTHealth).
Proning Team Became Key Part of Massachusetts General’s COVID-19 Care
A designated proning team — composed of about 70 OR nurses, OR assistants and outpatient physical therapists — became a key part of the COVID-19 care provided by Massachusetts General Hospital, responding around-the-clock to patients who needed turning and allowing critical care clinicians to focus on other aspects of care.
COVID-19 ARDS Focus of Latest American Thoracic Society/CSL Behring Research Grant Recipient
The ATS Research Program is pleased to announce that William Zhang, MD, of Weill Cornell Medical Center is the recipient of the 2020-2021 ATS/CSL Behring Research Award in Acute Respiratory Distress Syndrome. The $50,000 award will support Dr. Zhang’s research study, “Hyperferritinemia in COVID-19 ARDS: Friend or Foe?”
A new treatment that might keep COVID-19 patients off the ventilator
A new treatment is among the first known to reduce the severity of acute respiratory distress syndrome caused by the flu in animals, according to a new study.
How Reducing Body Temperature Could Help a Tenth of All ICU Patients
ROCKVILLE, MD – A tenth of all intensive care unit patients worldwide, and many critical patients with COVID-19, have acute respiratory distress syndrome (ARDS).
COVID-19 deaths really are different. But best practices for ICU care should still apply, studies suggest.
COVID-19 deaths are indeed different from other lung failure deaths, according to two recent studies, with 56% of COVID-19 patients dying primarily from the lung damage caused by the virus, compared with 22% of those whose lungs fail due to other causes. But, the researchers conclude, the kind of care needed to help sustain people through the worst cases of all forms of lung failure is highly similar, and just needs to be fine-tuned.
Researchers receive DOD funding to expand study of investigational drug to prevent ARDS in COVID-19 patients
Researchers evaluating whether an investigational oral drug, vadadustat, can help prevent acute respiratory distress syndrome (ARDS) in COVID-19 patients were awarded $5.1 million in funding from the U.S. Department of Defense (DOD) to expand the Phase II clinical trial at UTHealth.
Bringing harmony to chaos: UTHealth trauma surgeon repairs lives
By the time first responders rushed the patient to Red Duke Trauma Institute at Memorial Hermann-TMC, life was already slipping away through a stab wound in the neck. The goal of the team: resuscitate and transfer the patient to the operating room, where Laura J. Moore, MD, with UTHealth, would reconstruct his severed blood vessels.
U-Michigan Team Explores New Weapon Against COVID-19 Cytokine Storm
Researchers have created an experimental device that, instead of inhibiting inflammatory proteins in COVID-19 patients, changes the phenotype of circulating white blood cells, helping wean two patients off ECMO.
Unraveling the network of molecules that influence COVID-19 severity
Researchers from the Morgridge Institute for Research, the University of Wisconsin-Madison, and Albany Medical College have identified more than 200 molecular features that strongly correlate with COVID-19 severity, offering insight into potential treatment options for those with advanced disease.
Lack of Knowledge Is One Barrier to Prone Positioning in Severe ARDS Caused by COVID-19
A new study published online in the Annals of the American Thoracic Society examines ways to increase the use of prone positioning for patients with severe acute respiratory distress syndrome (ARDS), and develops specific implementation strategies that can assist in clinicians’ response to the COVID-19 pandemic. Prone positioning has been shown to reduce mortality related to severe ARDS, yet most patients with ARDS—up to 85 percent—do not receive this lifesaving therapy.
AACN Launches Micro-Credential for COVID-19 Patient Care
New micro-credential for nurses and other healthcare professionals who provide direct care for critically ill patients with COVID-19 is among the first for clinical care. AACN is the first professional nursing organization to offer a micro-credential.
Researchers Identify “Druggable” Signaling Pathway that Stimulates Lung Tissue Repair
Researchers at Children’s Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have identified a cellular pathway that can be targeted with a naturally occurring drug to stimulate lung tissue regeneration, which is necessary for recovery from multiple lung injuries. The findings, which were published today in Nature Cell Biology, could lead to better therapies for patients with lung disease, including acute respiratory distress syndrome (ARDS) due to COVID-19.
DNA webs may drive lung pathology in severe COVID-19
Sticky webs of DNA released from immune cells known as neutrophils may cause much of the tissue damage associated with severe COVID-19 infections, according to two new studies published September 14 in the Journal of Experimental Medicine (JEM). The research, conducted by independent groups in Belgium and Brazil, suggests that blocking the release of these DNA webs could be a new therapeutic target for the management of severe forms of COVID-19.
American Thoracic Society/CSL Behring Research Award in ARDS Announced
The ATS Research Program is pleased to announce the new ATS/CSL Behring Research Award in Acute Respiratory Distress Syndrome or ARDS. The award will provide $50,000 in funding for one year.
Unconventional T cells in severe COVID-19 patients could predict disease outcome
Researchers in France have discovered that patients suffering from severe COVID-19 show changes in a class of immune cells known as unconventional T cells. The study, published today in the Journal of Experimental Medicine (JEM), suggests that monitoring the activity of these cells in the blood of patients could predict the severity and course of the disease.
Researchers study whether vadadustat, an investigational therapy, could mitigate acute lung injury in COVID-19 patients
Physicians are studying whether vadadustat, an investigational therapy, could protect the lungs of COVID-19 patients by triggering the body’s protective response to low oxygen levels in a randomized Phase II clinical trial at UTHealth.
Standardized Curriculum Introduces ICU Nurses to ECMO
Vanderbilt University Medical Center designed and rapidly deployed a curriculum specifically to equip nurses new to ECMO with the knowledge, skills and confidence necessary to provide proficient and safe care for patients receiving ECMO. The pre-COVID ECMO training proved to be an effective, resource-efficient and pragmatic solution that can be used across different types of ICUs and across institutions.
Reducing severe breathlessness and psychological trauma in COVID-19 ARDS patients
A new Viewpoint article published online in the Annals of the American Thoracic Society examines ventilation and medication strategies that can help avoid psychological trauma for severe COVID-19 survivors treated for acute respiratory distress syndrome (ARDS) with mechanical ventilation.
Reducing Severe Breathlessness and Psychological Trauma in COVID-19 ARDS Survivors
A new paper published online in the Annals of the American Thoracic Society examines ventilation and medication strategies that can help avoid psychological trauma for severe COVID-19 survivors treated for acute respiratory distress syndrome (ARDS) with mechanical ventilation.
Analysis Does Not Find Two Distinct Subphenotypes of COVID-19 Related ARDS
In a new paper published online in the Annals of the American Thoracic Society, researchers have been unable to produce two theorized subphenotypes of COVID-19 related acute respiratory distress syndrome (ARDS). Scientists previously proposed that two phenotypes exist that differentiate patients with more severe COVID-19 and indicate that they should be treated differently. A phenotype is a set of characteristics used to classify a patient, which may influence disease management.
New remdesivir trial at UIC tests drug in combination with baricitinib
The University of Illinois at Chicago is enrolling patients in a second clinical trial to study the drug remdesivir as a treatment for COVID-19. Funded by the National Institute of Allergy and Infectious Disease (NIAID), this international randomized, placebo-controlled clinical trial will…
Simulation-based Training Helps Providers Prepare for Prone Position Ventilation for Patients With ARDS
An interprofessional simulation-based educational program helped Mount Sinai Hospital train nearly 90% of its medical ICU staff to care for patients in prone position, as part of its 2018 implementation of a new protocol related to prone position ventilation for patients with acute respiratory distress syndrome.
First COVID-19 patient in Texas enrolled in UTHealth stem cell therapy study at Memorial Hermann
The first COVID-19 patient in Texas has been enrolled in a stem cell therapy clinical trial for acute respiratory distress syndrome (ARDS) at The University of Texas Health Science Center at Houston (UTHealth).
American Association of Critical-Care Nurses Creates Custom COVID-19 Online Course
The American Association of Critical-Care Nurses has created an online course that specifically addresses the most serious reported symptoms from COVID-19. The course is available to all nurses, at no charge, to provide vital resources during this challenging time.