BPS20 | sciencenewsnet.in

New High-Throughput Method to Study Gene Splicing at an Unprecedented Scale Reveals New Details About the Process

Genes are like instructions, but with options for building more than one thing. Daniel Larson, senior investigator at the National Cancer Institute, studies this gene “splicing” process, which happens in normal cells and goes awry in blood cancers like leukemia.

Research Results

What Induces Sleep? For Fruit Flies It’s Stress at the Cellular Level

February 15, 2020 sarah Jonas Biophysical Society, Biophysical Society 64th Annual Meeting, Biophysical Society Annual Meeting, BPS, BPS20, Drosophila, Fruit Flies, Sleep, Stress, University of Oxford

Sleep-deprived fruit flies helped reveal what induces sleep. University of Oxford researchers Anissa Kempf, Gero Miesenböck, and colleagues reveal that fruit fly sleep is driven by oxidative stress, the imbalance of free radicals and antioxidants in the body.

Research Results

A New Way to Monitor Cancer Radiation Therapy Doses

February 15, 2020 sarah Jonas Arizona State University, ASU, Biophysical Society, Biophysical Society 64th Annual Meeting, Biophysical Society Annual Meeting, BPS, BPS20, Cancer, Radiation, Radiation Therapy

More than half of all cancer patients undergo radiation therapy and the dose is critical. Too much and the surrounding tissue gets damaged, too little and the cancer cells survive.

Research Results

Parkinson’s Disease Protein Structure Solved Inside Cells Using Novel Technique

February 15, 2020 sarah Jonas Biophysical Society, Biophysical Society 64th Annual Meeting, Biophysical Society Annual Meeting, BPS, BPS20, Uc San Diego

The top contributor to familial Parkinson’s disease is mutations in leucine-rich repeat kinase 2 (LRRK2), whose large and difficult structure has finally been solved, paving the way for targeted therapies.

Research Results

Like a Microscopic Mars Rover, a New Technique Tracks Individual Protein Movement on Live Cells

February 15, 2020 sarah Jonas Biophysical Society, Biophysical Society 64th Annual Meeting, Biophysical Society Annual Meeting, BPS, BPS20, Microscopy

The piece of gold that Richard Taylor was thrilled to track down weighed less than a single bacterium. Taylor, a postdoctoral fellow at the Max Planck Institute, was working to follow individual nanogold-labeled molecules that move just nanometers, billionths of a meter.

Research Results

Insects’ Ability to Smell is Phenomenally Diverse, a New Protein Structure Hints at How

February 15, 2020 sarah Jonas Biophysical Society, Biophysical Society 64th Annual Meeting, Biophysical Society Annual Meeting, BPS, BPS20, cryo-electron microscopy, Olfaction

Mosquitoes find us by our odor molecules binding to odor receptors on their antennae, bees are drawn to flowers the same way, whereas ticks detect an approaching host using receptors on their forelegs.

Research Results

Researchers Show How Ebola Virus Hijacks Host Lipids

February 15, 2020 sarah Jonas Biophysical Society, Biophysical Society 64th Annual Meeting, Biophysical Society Annual Meeting, BPS, BPS20, Ebola, Ebola Virus, FDA, Food And Drug Administration, Lipids

Robert Stahelin studies some of the world’s deadliest viruses. Filoviruses, including Ebola virus and Marburg virus, cause viral hemorrhagic fever with high fatality rates. Stahelin, professor at Purdue University, examines how these viruses take advantage of human host cells.

Research Results

Technique Can Label Many Specific DNAs, RNAs, or Proteins in a Single Tissue Sample

February 15, 2020 sarah Jonas biomolecular engineering, Biophysical Society, Biophysical Society 64th Annual Meeting, Biophysical Society Annual Meeting, BPS, BPS20, DNA, Harvard, Harvard Medical School, Harvard University

A new technique can label diverse molecules and amplify the signal to help researchers spot those that are especially rare. Called SABER (signal amplification by exchange reaction), Peng Yin’s lab at Harvard’s Wyss Institute first introduced this method last year and since have found ways to apply it to proteins, DNA and RNA.

Research Results

Cancer Immunotherapy Target Helps Fight Solid Tumors

February 15, 2020 sarah Jonas Biophysical Society 64th Annual Meeting, Biophysical Society Annual Meeting, BPS, BPS20, Cancer, CAR-T, cars, chimeric antigen receptor, Immunotherapy, tumors, UCLA

Yvonne Chen engineers immune cells to target their most evasive enemy: cancer. New cancer immunotherapies generate immune cells that are effective killers of blood cancers, but they have a hard time with solid tumors.