Breakthrough study on molecular interactions could improve development of new medicines

A first-of-its-kind study on molecular interactions by biomedical engineers in the University of Minnesota’s College of Science and Engineering will make it easier and more efficient for scientists to develop new medicines and other therapies for diseases such as cancer, HIV, and autoimmune diseases. The study resulted in a mathematical framework that researchers plan to use to develop a web-based app that other researchers can use to speed the development of new therapies for diseases.

Researchers Identify Key Structure of C. Difficle Bacteria That Could Lead to Future Treatments

– Researchers from the University of Maryland School of Medicine and their colleagues have identified the structure of the most lethal toxin produced by certain strains of Clostridium difficile bacteria, a potentially deadly infection associated with the use of antibiotics. The researchers mapped out the delivery and binding components of the toxin, which could pave the way for new drugs to neutralize it.

Hackensack University Medical Center Physicians Host Second Annual Evening on Urology Advances

Hackensack Meridian Health Hackensack University Medical Center Foundation held an event, Innovative Evening on Urology, to highlight advances and promising projects for the future in the field of urology. More than 200 guests — including physicians, Hackensack University Medical Center leaders, clinicians, vendors, and urology patients —attended the second annual fundraiser at the Edgewood Country Club. The event highlighted the Urology Department’s world-class team and groundbreaking technologies to raise critical philanthropic support for current research projects, educational programs, and innovative initiatives.

BP Looks to ORNL, ADIOS to Help Rein in Data

British Petroleum researchers invited ORNL data scientists to give the company’s high-performance computing team a tutorial of the laboratory’s ADIOS I/O middleware. ADIOS has helped researchers achieve scientific breakthroughs by providing a simple, flexible way to describe data in their code that may need to be written, read, or processed outside of the running simulation. ORNL researchers Scott Klasky and Norbert Podhorszki demonstrated how it could help the BP team accelerate their science by helping tackle their large, unique seismic datasets.

Tests Measure Solar Panel Performance Beyond Established Standards

In testing solar panels, the sun’s intensity, the spectral composition and the angle of light are important factors in understanding why certain panels are successful and others degrade more quickly. To address the knowledge gap in degradation mechanisms for various photovoltaic types, researchers performed tests over five years in which they collected weather data and panel performance information. The results are published in the Journal of Renewable and Sustainable Energy.

Bystander CPR Less Likely for People Living in Hispanic Neighborhoods Compared to Non-Hispanic Neighborhoods

People living in predominately Hispanic neighborhoods are less likely to receive CPR from a bystander following an out-of-hospital cardiac arrest compared to people living in non-Hispanic neighborhoods, researchers from Penn Medicine and the Duke University of School of Medicine reported in the journal Circulation. This same group also had a lower likelihood of survival.

How MSU helped reduce high-risk drinking among students

A university-wide social norms marketing campaign has reduced high-risk drinking and adverse outcomes of drinking, according to a new study from Michigan State University in the Journal of American College Health. MSU’s social norms campaign was created to educate MSU students about actual drinking behavior on campus. When misperceptions are corrected, behavior will change to be more consistent with the actual norm, said Dennis Martell, director of MSU Health Promotion.

Some Learning is A Whole-Brain Affair, Study Shows

Researchers at Johns Hopkins Medicine have successfully used a laser-assisted imaging tool to “see” what happens in brain cells of mice learning to reach out and grab a pellet of food. Their experiments, they say, add to evidence that such motor-based learning can occur in multiple areas of the brain, even ones not typically associated with motor control.

Structured, salary-only compensation plan for physicians is a model for pay equity, Mayo Clinic study finds

Gender pay equity in the field of medicine remains elusive. Gender-based pay differences have been shown to persist, even when controlling for experience, clinical productivity, academic rank and other factors. These inequities result in significantly lower lifetime earnings, job burnout and negative attitudes toward work, and adverse effects on the profession and society.

Switching tracks: Reversing electrons’ course through nature’s solar cells

Think of a train coming down the tracks to a switch point where it could go either to the right or the left — and it always goes to the right. Photosynthetic organisms have a similar switch point. New research from Washington University in St. Louis and Argonne National Laboratory coaxes electrons down the track that they typically don’t travel

Could Nursing Certification Make a Difference in Adopting Evidence-Based Practices?

A survey of critical care nurses in six UPMC hospitals found a strong association between nurses who were certified in critical care and their knowledge of and perceived value in specific evidence-based practices used to care for patients receiving mechanical ventilation, according to a study published in the American Journal of Critical Care.

Delivering TB Vaccine Intravenously Dramatically Improves Potency, Study Shows

Worldwide, more people die from tuberculosis than any other infectious disease, even though the vast majority were vaccinated. The vaccine just isn’t that reliable. But a new Nature study finds that simply changing the way the vaccine is administered could dramatically boost its protective power.