Revealing the mechanism of glial cell activity
Tag: Molecular Biology
Moving diagnostics out of the lab and into your hand
Electrochemical sensor platform technology could enable portable, multiplexed, point-of-care diagnostics for a wide range of applications
Photosynthesis seen in a new light by rapid X-ray pulses
The ability to transform sunlight into energy is one of Nature’s more remarkable feats. Scientists understand the basic process of photosynthesis, but many crucial details remain elusive, occurring at dimensions and fleeting time scales long deemed too minuscule to probe.…
TTUHSC researchers publish preclinical data on new drug combination to treat neuroblastoma
Neuroblastoma is the most common cancer outside of the brain in infants and young children and often fails to respond to therapy. Though it can appear in several areas of the body, it commonly develops as a solid tumor most…
Neural network fills in data gaps for spatial analysis of chromosomes
Machine learning enhances study of 3D genome structure in cell nucleus
Integrating imaging research across Europe
Euro-BioImaging established as a European Research Infrastructure Consortium for state-of-the-art imaging services in biological and biomedical research
Groundbreaking HIV vaccine design strategy shows promise in proof-of-principle tests
A new approach that targets young immune cells may also work for creating vaccines against the flu, dengue, malaria and hepatitis C.
Dundee researcher honoured with prestigious award
University of Dundee PhD student presented with a prestigious science award from the British Federation of Women Graduates (BFWG)
Sugar-coating proteins can help understand brain disease
A University of Dundee discovery has the potential to help scientists better understand neurological diseases such as Alzheimer’s and Parkinson’s
Targeted gene modification in animal pathogenic chlamydia
The human pathogenic bacterium Chlamydia trachomatis is the most common sexually transmitted bacterial pathogen worldwide. It is estimated to infect more than 100 million people each year and is a frequent cause of infertility. Moreover, Chlamydia trachomatis also causes eye…
Scientists crack structure of a novel enzyme linked to cell growth and cancer
UC Riverside-led study could lead to the development of drugs that target liver and other cancers
Genetically modified mice can show which functional foods can heal kidney disease
Scientists create a mouse model that can show kidney disease progression and treatment in live animals
Dr. Yamamoto receives the Karl Landsteiner Memorial Award and Lectureship
Dr. Fumiichiro Yamamoto receives the prestigious Karl Landsteiner Memorial Award and Lectureship for his work on blood group genes
Neuron circuitry from brain signals
Using machine learning to construct a map of neuronal connections
A solution to a hairy problem in forensic science
Making hair proteomics a practical method for forensic investigation
Scientists crack structure of a novel enzyme linked to cell growth and cancer
UC Riverside-led study could lead to the development of drugs that target liver and other cancers
Genetically modified mice can show which functional foods can heal kidney disease
Scientists create a mouse model that can show kidney disease progression and treatment in live animals
Dr. Yamamoto receives the Karl Landsteiner Memorial Award and Lectureship
Dr. Fumiichiro Yamamoto receives the prestigious Karl Landsteiner Memorial Award and Lectureship for his work on blood group genes
Neuron circuitry from brain signals
Using machine learning to construct a map of neuronal connections
A solution to a hairy problem in forensic science
Making hair proteomics a practical method for forensic investigation
SMART discovers breakthrough way to look at the surface of nanoparticles
New method to explore the surface of nanoparticles, unlike existing chemical procedures which have severe limitations
New research tool for studying mitochondrial disorders and aging
Researchers at Karolinska Institutet in Sweden have developed a new research tool for studying how mitochondrial protein synthesis is affected by disease, pharmaceuticals, ageing and different physiological situations such as exercise and diet. The study is presented in the scientific…
Potential drug targets for glioblastoma identified
Researchers at Karolinska Institutet in Sweden have identified 10 tumour-specific potential drug targets for the brain tumour glioblastoma. The results are presented in the scientific journal Cell Reports . “We have found disease-related changes in the cells that line the…
‘Big data’ for life sciences
A human protein co-regulation map reveals new insights into protein functions
Achilles heel of tumor cells
In 90 percent of all cases of colon cancer, the tumour cells have one thing in common: the APC gene is mutated. Research groups at Julius-Maximilians-Universität (JMU) Würzburg in Bavaria, Germany, were looking for targets in these cells that could…
Transient wave of hematopoietic stem cell production in late fetuses and young adults
Hematopoietic stem cells (HSCs) are responsible for the constant replenishment of all blood cells throughout life. One of the major challenges in regenerative medicine is to produce tailor-made HSCs to replace the defective ones in patients suffering from blood related…
Zebrafish study reveals developmental mechanisms of eye movement
Fralin Biomedical Research Institute leads multi-university team in neuroscience study
CNIO researchers describe a molecular strategy that helps prevent tumour formation in mice
The body’s process for manufacturing fatty acids is regulated by the enzyme FASN. In normal cells, this is not a very active process – except occasionally in the liver and adipose tissue – since most of the fatty acids we…
Gene-OFF switches tool up synthetic biology
Programmable repressor elements expand the toolbox of synthetic biologists, enabling more sophisticated and accurate diagnostic, environmental, and biofabrication approaches
EMBL spins the Sleeping Beauty transposase
New possibilities for gene therapies
Eelgrass acid and resveratrol produced by cell factories for the first time
Scientists are now able to produce a wide range of sulfated aromatic compounds such as antifouling eelgrass acid, resveratrol and vanillic acid derivatives using microbial production hosts
Transient wave of hematopoietic stem cell production in late fetuses and young adults
Hematopoietic stem cells (HSCs) are responsible for the constant replenishment of all blood cells throughout life. One of the major challenges in regenerative medicine is to produce tailor-made HSCs to replace the defective ones in patients suffering from blood related…
Ramping up to divide: An unstable protein is the master switch for cell division
An extremely unstable protein, Cln3, appears to be the master switch that activates cell division in budding yeast. Cln3 concentrations only reach high enough levels to trigger the cell division process when the rate of protein synthesis outpaces the rate…
CNIO researchers describe a molecular strategy that helps prevent tumour formation in mice
The body’s process for manufacturing fatty acids is regulated by the enzyme FASN. In normal cells, this is not a very active process – except occasionally in the liver and adipose tissue – since most of the fatty acids we…
Zebrafish study reveals developmental mechanisms of eye movement
Fralin Biomedical Research Institute leads multi-university team in neuroscience study
EMBL spins the Sleeping Beauty transposase
New possibilities for gene therapies
Gene-OFF switches tool up synthetic biology
Programmable repressor elements expand the toolbox of synthetic biologists, enabling more sophisticated and accurate diagnostic, environmental, and biofabrication approaches
Transient wave of hematopoietic stem cell production in late fetuses and young adults
Hematopoietic stem cells (HSCs) are responsible for the constant replenishment of all blood cells throughout life. One of the major challenges in regenerative medicine is to produce tailor-made HSCs to replace the defective ones in patients suffering from blood related…
Eelgrass acid and resveratrol produced by cell factories for the first time
Scientists are now able to produce a wide range of sulfated aromatic compounds such as antifouling eelgrass acid, resveratrol and vanillic acid derivatives using microbial production hosts
Ramping up to divide: An unstable protein is the master switch for cell division
An extremely unstable protein, Cln3, appears to be the master switch that activates cell division in budding yeast. Cln3 concentrations only reach high enough levels to trigger the cell division process when the rate of protein synthesis outpaces the rate…
Eelgrass acid and resveratrol produced by cell factories for the first time
Scientists are now able to produce a wide range of sulfated aromatic compounds such as antifouling eelgrass acid, resveratrol and vanillic acid derivatives using microbial production hosts
CNIO researchers describe a molecular strategy that helps prevent tumour formation in mice
The body’s process for manufacturing fatty acids is regulated by the enzyme FASN. In normal cells, this is not a very active process – except occasionally in the liver and adipose tissue – since most of the fatty acids we…
Ramping up to divide: An unstable protein is the master switch for cell division
An extremely unstable protein, Cln3, appears to be the master switch that activates cell division in budding yeast. Cln3 concentrations only reach high enough levels to trigger the cell division process when the rate of protein synthesis outpaces the rate…
Zebrafish study reveals developmental mechanisms of eye movement
Fralin Biomedical Research Institute leads multi-university team in neuroscience study
EMBL spins the Sleeping Beauty transposase
New possibilities for gene therapies
Gene-OFF switches tool up synthetic biology
Programmable repressor elements expand the toolbox of synthetic biologists, enabling more sophisticated and accurate diagnostic, environmental, and biofabrication approaches
Red Algae Thrive Despite Ancestor’s Massive Loss of Genes
You’d think that losing 25 percent of your genes would be a big problem for survival. But not for red algae, including the seaweed used to wrap sushi. An ancestor of red algae lost about a quarter of its genes roughly one billion years ago, but the algae still became dominant in near-shore coastal areas around the world, according to Rutgers University–New Brunswick Professor Debashish Bhattacharya, who co-authored a study in the journal Nature Communications.
Newly discovered protein is the permit to the powerhouse of cells
Medical University of South Carolina researchers report in Science Advances that they have discovered a protein, P17/PERMIT, that is key to recycling aging mitochondria and could be a connection between age-related diseases such as cancer and Alzheimer’s
Researchers discover the ‘KARAPPO’ gene and illuminate vegetative reproduction
Applications expected in agricultural and horticultural fields
Keep quiet or be eliminated: How cell competition modulates morphogen gradients
Osaka University-led study shows that communication between cells with normal and abnormal Wnt/β-catenin activity causes abnormal cells to die through production of reactive oxygen species