The effectiveness of current treatments for melanoma, the deadliest form of skin cancer, could be improved by using approaches that wipe out the ‘survival system’ of cancer cells according to a study published in Nature Communications today.* Researchers from the…
Tag: Molecular Biology
Salk Institute receives Charity Navigator’s highest rating for ninth consecutive time
Status achieved by only three percent of nonprofits
Blocking a survival mechanism could tackle melanoma treatment resistance
The effectiveness of current treatments for melanoma, the deadliest form of skin cancer, could be improved by using approaches that wipe out the ‘survival system’ of cancer cells according to a study published in Nature Communications today.* Researchers from the…
Salk Institute receives Charity Navigator’s highest rating for ninth consecutive time
Status achieved by only three percent of nonprofits
TGen-USC researchers link sisters’ paralysis to an ‘extremely rare’ genetic variant
Diagnosis by TGen’s Center for Rare Childhood Disorders gives solace to parents who searched a quarter-century for answers
TGen-USC researchers link sisters’ paralysis to an ‘extremely rare’ genetic variant
Diagnosis by TGen’s Center for Rare Childhood Disorders gives solace to parents who searched a quarter-century for answers
Discovery: New biomarker for cancer stem cells
Protein linked to tumor survival and spread
Twenty-seven life scientists become EMBO Young Investigators
Heidelberg, 13 November 2019 – EMBO congratulates twenty-seven life scientists on their selection as new EMBO Young Investigators. They join a network of 129 current and 340 former Young Investigators, and will begin their four-year programme tenure in January 2020.…
System by which plants have formed secondary buds since ancient times illuminated
A collaborative research group has succeeded in identifying an important transcription factor, GCAM1, which allows liverwort plants to asexually reproduce through creating clonal progenies (vegetative reproduction). Furthermore, this transcription factor was revealed to have the same origin as those which…
Novel mathematical framework provides a deeper understanding of how drugs interact
Combining two or more drugs can be an effective treatment of diverse diseases, such as cancer. Yet, at the same time, the wrong drug combination can cause major side effects. Currently there is no systematic understanding of how different drugs…
Something old, something new in the ocean’s blue
The discovery of a forgotten metabolic pathway adds a new dimension to the global carbon cycle
Researchers create model to predict children likely to go into septic shock
Algorithm draws on electronic medical records as soon as patient arrives
Crick researchers unravel protective properties of telomere t-loops
Loops at the ends of telomeres play a vital protective role preventing irretrievable damage to chromosomes, according to new research from the Crick. The study, published in Nature , showed how the winding and unwinding of ‘t-loops’ at the end…
Chitin-binding proteins override host plant’s resistance to fungal infection
An insoluble complex carbohydrate, chitin makes up fungal walls and plays a significant role in the interaction between fungal pathogens and their plant hosts. Plant cells harbor immune receptors that perceive chitin and work to stop fungal infection. However, fungal…
Extinct giant ape directly linked to the living orangutan
Researchers have succeeded in reconstructing the evolutionary relationship between a 2-million-year-old giant primate and the living orangutan; it is the first time genetic material this old has been retrieved from a fossil in a subtropical area
How the cellular recycling system is put on hold while cells divide
Research confirms repression of autophagy during mitosis
Discovery: New biomarker for cancer stem cells
Protein linked to tumor survival and spread
Twenty-seven life scientists become EMBO Young Investigators
Heidelberg, 13 November 2019 – EMBO congratulates twenty-seven life scientists on their selection as new EMBO Young Investigators. They join a network of 129 current and 340 former Young Investigators, and will begin their four-year programme tenure in January 2020.…
System by which plants have formed secondary buds since ancient times illuminated
A collaborative research group has succeeded in identifying an important transcription factor, GCAM1, which allows liverwort plants to asexually reproduce through creating clonal progenies (vegetative reproduction). Furthermore, this transcription factor was revealed to have the same origin as those which…
Something old, something new in the ocean’s blue
The discovery of a forgotten metabolic pathway adds a new dimension to the global carbon cycle
Novel mathematical framework provides a deeper understanding of how drugs interact
Combining two or more drugs can be an effective treatment of diverse diseases, such as cancer. Yet, at the same time, the wrong drug combination can cause major side effects. Currently there is no systematic understanding of how different drugs…
Researchers create model to predict children likely to go into septic shock
Algorithm draws on electronic medical records as soon as patient arrives
Crick researchers unravel protective properties of telomere t-loops
Loops at the ends of telomeres play a vital protective role preventing irretrievable damage to chromosomes, according to new research from the Crick. The study, published in Nature , showed how the winding and unwinding of ‘t-loops’ at the end…
Chitin-binding proteins override host plant’s resistance to fungal infection
An insoluble complex carbohydrate, chitin makes up fungal walls and plays a significant role in the interaction between fungal pathogens and their plant hosts. Plant cells harbor immune receptors that perceive chitin and work to stop fungal infection. However, fungal…
How the cellular recycling system is put on hold while cells divide
Research confirms repression of autophagy during mitosis
Extinct giant ape directly linked to the living orangutan
Researchers have succeeded in reconstructing the evolutionary relationship between a 2-million-year-old giant primate and the living orangutan; it is the first time genetic material this old has been retrieved from a fossil in a subtropical area
Scientists crack rabies virus weaponry
Researchers from have found a way to stop the rabies virus shutting down the body’s immune defence against it.
Penn team discovers epigenetic pathway that controls social behavior in carpenter ants
Study reveals the behavior of Major ant ‘soldiers’ can be successfully reprogrammed up to 5 days after they hatch; reprogramming was ineffective at the 10-day mark
Cardiologists establish how e-cigarettes damage the brain, blood vessels and lungs
Cardiologists have issued a stark warning about the dangers of e-cigarettes, particularly for young people, as results of new research show the damage they cause to the brain, heart, blood vessels and lungs. The study, which is published in the…
SMAD2 and SMAD3, two almost identical transcription factors but with distinct roles
Scientists at the Institute for Research in Biomedicine (IRB Barcelona), in collaboration with the Sloan Kettering Institute (New York, US), have published the structural and functional keys that distinguish two very similar transcription factors, namely SMAD2 and SMAD3. SMADs form…
SMAD2 and SMAD3, two almost identical transcription factors but with distinct roles
Scientists at the Institute for Research in Biomedicine (IRB Barcelona), in collaboration with the Sloan Kettering Institute (New York, US), have published the structural and functional keys that distinguish two very similar transcription factors, namely SMAD2 and SMAD3. SMADs form…
Scientists crack rabies virus weaponry
Researchers from have found a way to stop the rabies virus shutting down the body’s immune defence against it.
Penn team discovers epigenetic pathway that controls social behavior in carpenter ants
Study reveals the behavior of Major ant ‘soldiers’ can be successfully reprogrammed up to 5 days after they hatch; reprogramming was ineffective at the 10-day mark
Potential vitamin and Alzheimer’s drug produced in yeast
Ergothioneine is a natural amino acid with antioxidative properties. It prevents cellular stress, which can lead to brain diseases, neurological damage and cancer. In rats and roundworms, research shows that ergothioneine has promising effects in preventing neurodegenerative diseases such as…
UC research finds potential target for tumor-causing condition
CINCINNATI — University of Cincinnati researchers have found additional ways to target the molecular processes involved in activating a certain protein complex to potentially develop new therapies for a tumor-causing disorder. These findings are being published in the Nov. 11…
Identifying the efficacy of treating encephalitis in leukemia therapy
Revealing the mechanism of glial cell activity
Study reveals how two strains of one bacterium combine to cause flesh-eating infection
An international team including University of Maryland scientists revealed how genetic variations in a single species of bacteria can amplify infection
Too much sugar doesn’t put the brakes on turbocharged crops
Plants make sugars to form leaves to grow and produce grains and fruits through the process of photosynthesis, but sugar accumulation can also slow down photosynthesis. Researching how sugars in plants control photosynthesis is therefore an important part of finding…
Moving diagnostics out of the lab and into your hand
Electrochemical sensor platform technology could enable portable, multiplexed, point-of-care diagnostics for a wide range of applications
The pathway to Parkinson’s takes a surprising twist
In neurodegenerative conditions like Parkinson’s disease, a specific group of neurons start to die one by one, causing movement problems and other symptoms. Scientists have long focused on finding out why these neurons die. Now it turns out, they might…
New symposium highlights research on targeting of incurable diseases via RNA
Titled: ‘RNA – From Biology to Drug Discovery,’ day-long conference to focus on translational promise of a novel targeting strategy
Potential vitamin and Alzheimer’s drug produced in yeast
Ergothioneine is a natural amino acid with antioxidative properties. It prevents cellular stress, which can lead to brain diseases, neurological damage and cancer. In rats and roundworms, research shows that ergothioneine has promising effects in preventing neurodegenerative diseases such as…
UC research finds potential target for tumor-causing condition
CINCINNATI — University of Cincinnati researchers have found additional ways to target the molecular processes involved in activating a certain protein complex to potentially develop new therapies for a tumor-causing disorder. These findings are being published in the Nov. 11…
CRISPR: More than just for gene editing?
researcher finds new use for revolutionary gene-splicing tool; Electrochemical CRISPR platform could lead to quick blood test for disease identification through detection of important nucleic acids, HPV or Parvo
Study reveals how two strains of one bacterium combine to cause flesh-eating infection
An international team including University of Maryland scientists revealed how genetic variations in a single species of bacteria can amplify infection
Identifying the efficacy of treating encephalitis in leukemia therapy
Revealing the mechanism of glial cell activity
Moving diagnostics out of the lab and into your hand
Electrochemical sensor platform technology could enable portable, multiplexed, point-of-care diagnostics for a wide range of applications
Too much sugar doesn’t put the brakes on turbocharged crops
Plants make sugars to form leaves to grow and produce grains and fruits through the process of photosynthesis, but sugar accumulation can also slow down photosynthesis. Researching how sugars in plants control photosynthesis is therefore an important part of finding…
CRISPR: More than just for gene editing?
researcher finds new use for revolutionary gene-splicing tool; Electrochemical CRISPR platform could lead to quick blood test for disease identification through detection of important nucleic acids, HPV or Parvo
The pathway to Parkinson’s takes a surprising twist
In neurodegenerative conditions like Parkinson’s disease, a specific group of neurons start to die one by one, causing movement problems and other symptoms. Scientists have long focused on finding out why these neurons die. Now it turns out, they might…