Heidelberg, 25 November 2019 – EMBO Press is pleased to announce the appointment of systems biologist M. Madan Babu as the new Chief Editor of Molecular Systems Biology . Madan Babu, who heads the regulatory genomics and systems biology group…
Tag: Molecular Biology
Under the lens: Link between macular degeneration and retinitis pigmentosa
University of Houston research team examines eye disease with $2.5 million award
Konstanz-based CRC 969 to receive additional funding
The Konstanz-based research in the area of cellular proteostasis will receive funding in the amount of approximately EUR ten million for another four years, at the end of which it will have reached its maximum funding period of twelve years.…
New approach to treating incurable leukemia in children discovered
Acute lymphoblastic leukemia (ALL) is a form of blood cancer that primarily affects children and young people. It involves large quantities of malignant progenitor cells building up in a person’s blood instead of healthy white blood cells. This is often…
The nature of salmonella is changing — and it’s meaner
EAST LANSING, Mich. — Salmonella is acting up in Michigan, and it could be a model for what’s happening in other states, according to a new Michigan State University study. The study, appearing in Frontiers in Medicine , documents a…
Under the lens: Link between macular degeneration and retinitis pigmentosa
University of Houston research team examines eye disease with $2.5 million award
How does the prion protein clump? DNA-modulated liquid droplets may explain
Brazilian scientists have found that prion proteins form liquid droplets that can turn into a solid and toxic state, and that DNA modulates this process
Bacteria-infecting viruses bind mucosal surface and protect from disease
Mucosal surfaces protect organisms from external stressors and disease. Bacteriophages, viruses that infect bacteria, have been shown to preferentially bind to mucosal surfaces. This has been suggested to provide an extra level of immunity against bacterial infections. Researchers at the…
Unraveling gene expression
The DNA of a single cell is 2-3 meters long end-to-end. To fit and function, DNA is packaged around specialized proteins. These DNA-protein complexes are called nucleosomes, and they are a small part of a larger structure called chromatin. Nucleosomes…
Unraveling gene expression
The DNA of a single cell is 2-3 meters long end-to-end. To fit and function, DNA is packaged around specialized proteins. These DNA-protein complexes are called nucleosomes, and they are a small part of a larger structure called chromatin. Nucleosomes…
Nature’s secret recipe for making leaves
The secret recipe nature uses to make the diverse leaf shapes we see everywhere around us has been revealed in research. The discovery comes in a study of the carnivorous plant Utricularia gibba (bladderwort) which has evolved unusual cup-shaped leaves…
Magnesium deprivation stops pathogen growth
When pathogens invade the cells, our body combats them using various methods. Researchers at the University of Basel’s Biozentrum have now been able to show how a cellular pump keeps such invading pathogens in check. As the researchers report in…
Melanin-producing Streptomyces are more likely to colonize plants
Plant growth-promoting Streptomyces assemble into the internal, root endophytic compartments of a wide variety of plants around the world. These bacteria are well-known for their ability to produce a huge array of secondary metabolites and also protect against pests. Recent…
Researchers develop new database of druggable fusion targets
When sections from two separate genes merge due to various factors, such as translocation or splicing, the hybrid that is formed is called a gene fusion. In recent years, it has been discovered that these fusion events play a vital…
How do gliomas evolve?
The Glioma Longitudinal Analysis (GLASS) Consortium finds longitudinal molecular trajectories of diffuse glioma in adults
Could sphingolipids help solve a racial paradox in heart disease?
When it comes to predicting heart disease in African Americans, measuring HDL and LDL cholesterol is not enough. A Medical University of South Carolina study suggests that sphingolipid levels could one day hold the key
Scientists find promising drug combination against lethal childhood brain cancers
Studies in cell and animal models reveal insights into cancer cells’ vulnerability that could lead to new strategies against brain cancers
The ever-changing brain: Shining a light on synaptic plasticity
Researchers study key neural receptor involved in learning and memory
Researchers discover molecular light switch in photoreceptor cells
Researchers from Osaka University identify an enzyme that helps control vision in bright and dark spaces, with significant implications for the prevention of light-induced vision damage
RNA regulation is crucial for embryonic stem cell differentiation
Embryonic stem cells (ESCs) are distinguished by their dual ability to self-renew and their potential to differentiate, both of which require tight regulatory control. During the differentiation of ESCs, various cells develop into specialised cell types such as skin cells,…
Children’s Tumor Foundation and DELopen increase access to compounds for neurofibromatosis
New York: November 19, 2019 – The Children’s Tumor Foundation (CTF), an innovative and global neurofibromatosis (NF) research foundation announced today a collaboration with DELopen, a DNA-encoded library technology platform sponsored by WuXi AppTec, a leading global provider of R&D…
Deep-sea bacteria copy their neighbors’ diet
A new group of symbiotic bacteria living with deep-sea mussels surprises with the way they fix carbon.
Researchers develop a database to aid in identifying key genes for bacterial infections
BacFITBase helps identify therapeutic targets for the production of new antibiotics
Cellular calpain proteases can cleave the enteroviral polyprotein
Research highlights the potential of calpain inhibitor as an antiviral against enteroviruses
Scientists develop a new method to detect light in the brain
Researchers from Istituto Italiano di Tecnologia, University of Salento, and Harvard Medical School have developed a new light-based method to capture and pinpoint the epicenter of neural activity. The study published on Nature Methods
RNA regulation is crucial for embryonic stem cell differentiation
Embryonic stem cells (ESCs) are distinguished by their dual ability to self-renew and their potential to differentiate, both of which require tight regulatory control. During the differentiation of ESCs, various cells develop into specialised cell types such as skin cells,…
Children’s Tumor Foundation and DELopen increase access to compounds for neurofibromatosis
New York: November 19, 2019 – The Children’s Tumor Foundation (CTF), an innovative and global neurofibromatosis (NF) research foundation announced today a collaboration with DELopen, a DNA-encoded library technology platform sponsored by WuXi AppTec, a leading global provider of R&D…
Deep-sea bacteria copy their neighbors’ diet
A new group of symbiotic bacteria living with deep-sea mussels surprises with the way they fix carbon.
Researchers develop a database to aid in identifying key genes for bacterial infections
BacFITBase helps identify therapeutic targets for the production of new antibiotics
Cellular calpain proteases can cleave the enteroviral polyprotein
Research highlights the potential of calpain inhibitor as an antiviral against enteroviruses
Scientists develop a new method to detect light in the brain
Researchers from Istituto Italiano di Tecnologia, University of Salento, and Harvard Medical School have developed a new light-based method to capture and pinpoint the epicenter of neural activity. The study published on Nature Methods
Genetic alterations caused by cancer therapies identified
Living implies change. This is what happens to the cells of our bodies as we grow older: they accumulate genetic alterations, most of which are harmless. However, in some specific cases, these mutations can affect certain genes and can lead…
Ohio University research shows ‘bad cholesterol’ is only as unhealthy as its composition
Research demonstrates that current guidelines for diagnosing risk are ‘dangerously misleading’
Researchers split the ‘AtoM’ in search of a treatment for rheumatoid arthritis
Researchers at Osaka University discover a new type of bone-dissolving osteoclast that contributes to rheumatoid arthritis
One-two punch drug combination offers hope for pancreatic cancer therapy
Study provides rationale for an immediate clinical trial evaluating the 2 therapies
Structure of a mitochondrial ATP synthase
ATP synthase is a universal molecular machine for energy conversion. By coupling to cellular respiration in mitochondria, it catalyzes conversion of chemical energy of cells. Mitochondrial ATP synthase is composed of dimers that, when come together, form membrane curvature that…
Metabolic syndrome: New use for an old drug
The syndrome, which affects more than 35% of the over-50 population in Western countries, could be treated with Ibrutinib, a drug that has already been approved for other diseases
Climate change could double greenhouse gas emissions from freshwater lakes
Every drop of fresh water contains thousands of different organic molecules that have previously gone unnoticed. By measuring the diversity of these molecules and how they interact with the environment around them, research has revealed an invisible world that affects…
Article proposes important mucin link between microbial infections and many cancers
It is generally known that viruses, with their cell-invading capabilities, can be responsible for a number of different cancers. What is less broadly discussed are the cancer-causing capabilities of bacteria, or the processes by which they may cause malignancy. In…
Protein imaging at the speed of life
The European XFEL marks a new age of protein movie-making that enables enzymes involved in disease to be observed in real time
The little duck that could: Study finds endangered Hawaiian duck endures
The endangered Hawaiian duck, or koloa, the only endemic duck remaining on the main Hawaiian Islands, is threatened with genetic extinction due to interbreeding with feral mallards. This has led to the creation of hybrid forms of the koloa. But…
Genetic alterations caused by cancer therapies identified
Living implies change. This is what happens to the cells of our bodies as we grow older: they accumulate genetic alterations, most of which are harmless. However, in some specific cases, these mutations can affect certain genes and can lead…
Ohio University research shows ‘bad cholesterol’ is only as unhealthy as its composition
Research demonstrates that current guidelines for diagnosing risk are ‘dangerously misleading’
Researchers split the ‘AtoM’ in search of a treatment for rheumatoid arthritis
Researchers at Osaka University discover a new type of bone-dissolving osteoclast that contributes to rheumatoid arthritis
The little duck that could: Study finds endangered Hawaiian duck endures
The endangered Hawaiian duck, or koloa, the only endemic duck remaining on the main Hawaiian Islands, is threatened with genetic extinction due to interbreeding with feral mallards. This has led to the creation of hybrid forms of the koloa. But…
One-two punch drug combination offers hope for pancreatic cancer therapy
Study provides rationale for an immediate clinical trial evaluating the 2 therapies
Structure of a mitochondrial ATP synthase
ATP synthase is a universal molecular machine for energy conversion. By coupling to cellular respiration in mitochondria, it catalyzes conversion of chemical energy of cells. Mitochondrial ATP synthase is composed of dimers that, when come together, form membrane curvature that…
Scientists discover how the molecule-sorting station in our cells is formed and maintained
New mechanism to explain how the cell organelle that sorts and distributes substances entering a cell is formed and maintained
Cell bio society’s journal joins portable peer review platform
Molecular Biology of the Cell (MBoC) is one of the first journals to participate in a new platform that enables journal-independent, “portable” peer review.
Genetic Variation in Individual Brain Cell Types May Predict Disease Risk
Researchers identified non-coding regions of the human genome that control the development and function of four brain cell types and mapped genetic risk variants for psychiatric diseases. They found that risk variants for Alzheimer’s disease were enriched in microglia-specific regulatory elements.