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UrduTo understand the molecular bases of cancer, it is imperative to determine the genetic alterations responsible for the development and spread of this condition and to identify the mechanisms through which healthy cells become malignant. In the last twenty years,…
Tag: Molecular Biology
Climate change and human activities threatens picky penguins
Eating a krill-only diet has made one variety of Antarctic penguin especially susceptible to the impacts of climate change, according to new research involving the University of Saskatchewan (USask) which sheds new light on why some penguins are winners and…
New clues about the origins of familial forms of Amyotrophic lateral sclerosis
A team led by Brazilian researcher Elis Eleutherio, professor at the Federal University of Rio de Janeiro, in partnership with Tiago Outeiro, at University of Goettingen, Germany, made important progress in understanding the conformation and accumulation of certain proteins involved…
Decades old debate settled: Golgi key to maintenance of molecule-sorting station in cells
New mechanism to explain how the cell organelle that sorts and distributes substances entering a cell is formed and maintained
Oat pathogen defence discovery marks an important milestone
Researchers have identified the critical last pieces of a genetic defence system that gives oats resistance to soil pathogens. The discovery opens significant opportunities for scientists and breeders to introduce versions of this defence mechanism into other crops. It is…
Climate change and human activities threatens picky penguins
Eating a krill-only diet has made one variety of Antarctic penguin especially susceptible to the impacts of climate change, according to new research involving the University of Saskatchewan (USask) which sheds new light on why some penguins are winners and…
Anthracnose alert: How bacteria prime fifth-biggest global grain crop against deadly fungus
Anthracnose of Sorghum bicolor devastates crops of the drought- and heat-resistant cereal worldwide. Priming with rhizobacteria can boost the plants’ resistance and tolerance against a wide range of adverse conditions such as microbial attacks. University of Johannesburg researchers decoded how…
Scientists reveal the structure of viral rhodopsins
The structure of an Organic Lake Phycodnavirus rhodopsin II (OLPVRII), which is a unique protein found in the genome of giant viruses, has been determined thanks to the work of MIPT graduates and PhD students. The paper was published in…
Cell-free synthetic biology comes of age
Cell-free systems stand to dramatically impact society, from the environment to medicine to education
EMBL and Leica sign open innovation collaboration agreement
EMBL often cooperates with industry partners, and has cooperated successfully with Leica for many years. Based on this strong partnership, Leica is among the companies supporting the upcoming EMBL Imaging Centre, which is currently under construction at the EMBL campus…
Designing and repurposing cell receptors
Called the “second secret of life”, allostery is one of the most fundamental processes of biology and has been a central focus among scientists across the life sciences spectrum, from fundamental biology to drug development. But what is allostery? In…
Protein defect leaves sperm chasing their tails
A team led by researchers from Osaka University identify a protein required for electrical signal sensing, which, when defective, causes sperm to swim in circles
Silencing retroviruses to awaken cell potential
Researchers led by a team from the University of Tsukuba identify a protein that suppresses retroviruses in the human genome, allowing the reprogramming of somatic cells to unlock their hidden potential
Two Rutgers Professors Named Fellows of AAAS
Two Rutgers professors have been named fellows of the American Association for the Advancement of Science (AAAS) this year, an honor awarded to AAAS members by their peers. They join 441 other AAAS members named new fellows because of their scientifically or socially distinguished efforts to advance science or its applications. The fellows will be presented an official certificate and a gold and blue (representing science and engineering, respectively) rosette pin on Feb. 15 at the AAAS Fellows Forum during the 2020 AAAS Annual Meeting in Seattle, Washington.
Six Berkeley Lab Scientists Named AAAS Fellows
Six scientists from the Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) have been named Fellows of the American Association for the Advancement of Science (AAAS).
A novel pathway to target colorectal cancer
Investigators at the Medical University of South Carolina report in Gastroenterology that PGE2, a signaling molecule involved in inflammation, promotes colorectal cancer progression
Once hidden cellular structures emerge in fight against viruses
A University of Arizona researcher describes how a cellular structure that was once lost to science combats attacks waged in the ‘world’s oldest war’
Recrutement of a lateral root developmental pathway into root nodule formation of legumes
Peas and other legumes develop spherical or cylindrical structures — called nodules — in their roots to establish a mutually beneficial relationship with bacteria that convert atmospheric nitrogen into a useable nutrient for the legume plant. Root nodule symbiosis enables…
Splicing factor to blame in triple negative breast cancer
A splicing factor called TRA2B enhances triple negative breast cancers’ ability to grow and metastasize.
KBRI team reduces neurodegeneration associated with dementia in animal models
PTK2/FAK regulates UPS impairment via SQSTM1/p62 phosphorylation in TARDBP/TDP-43 proteinopathies
New migraine medications could endanger patients with high blood pressure
The neuropeptide αCGRP (α calcitonin gene-related peptide) works in two different ways. It leads to inflammation and dilates the blood vessels right at the release point of the nerve cells, for example in the meninges, which can trigger migraine attacks.…
December’s SLAS Discovery special issue now available
‘Membrane Proteins: New Approaches to Probes, Technologies and Drug Design’ now accessible through December 20
December’s SLAS technology feature article now available
‘Automated System for Small-Population Single-Particle Processing Enabled by Exclusive Liquid Repellency’ now accessible through December 20
Once hidden cellular structures emerge in fight against viruses
A University of Arizona researcher describes how a cellular structure that was once lost to science combats attacks waged in the ‘world’s oldest war’
Splicing factor to blame in triple negative breast cancer
A splicing factor called TRA2B enhances triple negative breast cancers’ ability to grow and metastasize.
Scientists clarify light harvesting in green algae
Algae are indispensable because they generate about 50% of primary organic matter and account for about 50% of all oxygen on Earth. They produce oxygen through oxygenic photosynthesis -a biological process that “harvests” light and turns it into chemical energy.…
Immunity — master regulator of liver metabolism identified during infection
Surprisingly, the antiviral cytokine type I interferon (IFN-I) was found to be a master regulator of metabolic pathways in liver cells. The researchers focused on the urea cycle, a central metabolic node, and found that it is disrupted by IFN-I…
Six Berkeley Lab scientists named AAAS fellows
Honorees recognized for achievements in heavy element chemistry, tectonics, microbial photosynthesis, geological processes, particle physics, and biomolecular engineering
New migraine medications could endanger patients with high blood pressure
The neuropeptide αCGRP (α calcitonin gene-related peptide) works in two different ways. It leads to inflammation and dilates the blood vessels right at the release point of the nerve cells, for example in the meninges, which can trigger migraine attacks.…
KBRI team reduces neurodegeneration associated with dementia in animal models
PTK2/FAK regulates UPS impairment via SQSTM1/p62 phosphorylation in TARDBP/TDP-43 proteinopathies
Regulator of plant immunity tagged
A new actor in the immune system of plants has been identified. KAUST scientists have identified the protein MAP4K4 is needed to mount proper defenses against environmental pathogens. The discovery helps explain the tight control of immune signaling in plants…
Scientists clarify light harvesting in green algae
Algae are indispensable because they generate about 50% of primary organic matter and account for about 50% of all oxygen on Earth. They produce oxygen through oxygenic photosynthesis -a biological process that “harvests” light and turns it into chemical energy.…
A novel pathway to target colorectal cancer
Investigators at the Medical University of South Carolina report in Gastroenterology that PGE2, a signaling molecule involved in inflammation, promotes colorectal cancer progression
Immunity — master regulator of liver metabolism identified during infection
Surprisingly, the antiviral cytokine type I interferon (IFN-I) was found to be a master regulator of metabolic pathways in liver cells. The researchers focused on the urea cycle, a central metabolic node, and found that it is disrupted by IFN-I…
Recrutement of a lateral root developmental pathway into root nodule formation of legumes
Peas and other legumes develop spherical or cylindrical structures — called nodules — in their roots to establish a mutually beneficial relationship with bacteria that convert atmospheric nitrogen into a useable nutrient for the legume plant. Root nodule symbiosis enables…
Six Berkeley Lab scientists named AAAS fellows
Honorees recognized for achievements in heavy element chemistry, tectonics, microbial photosynthesis, geological processes, particle physics, and biomolecular engineering
December’s SLAS Discovery special issue now available
‘Membrane Proteins: New Approaches to Probes, Technologies and Drug Design’ now accessible through December 20
Regulator of plant immunity tagged
A new actor in the immune system of plants has been identified. KAUST scientists have identified the protein MAP4K4 is needed to mount proper defenses against environmental pathogens. The discovery helps explain the tight control of immune signaling in plants…
December’s SLAS technology feature article now available
‘Automated System for Small-Population Single-Particle Processing Enabled by Exclusive Liquid Repellency’ now accessible through December 20
Molecular Systems Biology appoints M. Madan Babu as new Chief Editor
Heidelberg, 25 November 2019 – EMBO Press is pleased to announce the appointment of systems biologist M. Madan Babu as the new Chief Editor of Molecular Systems Biology . Madan Babu, who heads the regulatory genomics and systems biology group…
Under the lens: Link between macular degeneration and retinitis pigmentosa
University of Houston research team examines eye disease with $2.5 million award
Konstanz-based CRC 969 to receive additional funding
The Konstanz-based research in the area of cellular proteostasis will receive funding in the amount of approximately EUR ten million for another four years, at the end of which it will have reached its maximum funding period of twelve years.…
New approach to treating incurable leukemia in children discovered
Acute lymphoblastic leukemia (ALL) is a form of blood cancer that primarily affects children and young people. It involves large quantities of malignant progenitor cells building up in a person’s blood instead of healthy white blood cells. This is often…
The nature of salmonella is changing — and it’s meaner
EAST LANSING, Mich. — Salmonella is acting up in Michigan, and it could be a model for what’s happening in other states, according to a new Michigan State University study. The study, appearing in Frontiers in Medicine , documents a…
Under the lens: Link between macular degeneration and retinitis pigmentosa
University of Houston research team examines eye disease with $2.5 million award
Konstanz-based CRC 969 to receive additional funding
The Konstanz-based research in the area of cellular proteostasis will receive funding in the amount of approximately EUR ten million for another four years, at the end of which it will have reached its maximum funding period of twelve years.…
New approach to treating incurable leukemia in children discovered
Acute lymphoblastic leukemia (ALL) is a form of blood cancer that primarily affects children and young people. It involves large quantities of malignant progenitor cells building up in a person’s blood instead of healthy white blood cells. This is often…
Aquatic microorganisms offer important window on the history of life
The air, earth and water of our planet are pulsating with living things. Yet, a vast and diverse web of life exists, about which almost nothing is known. This is the world of flagellates, tiny organisms that persist in staggering…
The mechanism of programmed aging: The way to creation a real remedy for senescence
The article by Dr. Alexander G. Trubitsyn is published in Current Aging Science, 2019
Wearable sweat sensor detects gout-causing compounds
There are numerous things to dislike about going to the doctor: Paying a copay, sitting in the waiting room, out-of-date magazines, sick people coughing without covering their mouths. For many, though, the worst thing about a doctor’s visit is getting…