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UrduScientists are developing ways to detect and identify not only new, previously unseen forms of fentanyl but also newer and more dangerous synthetic opioids known as nitazenes.
Tag: Mass Spectrometry
Sniff Test for Explosives Detection Extends Its Reach
Scientists have developed a way to detect tiny amounts of hard-to-detect explosives more than eight feet away.
Roche showcases solutions for laboratories of the future at the Association for Diagnostics & Laboratory Medicine 2024 Clinical Lab Expo
● Roche will unveil the next generation of core lab and molecular systems, including a total solution for clinical mass spectrometry.
● Attendees can experience firsthand how fully integrated systems and data solutions can streamline lab operations, optimize resources and expedite care.
The Time Is Now for Artificial Intelligence, Machine Learning
From artificial intelligence (AI) and data integration to natural language processing and statistics, the Cedars-Sinai Department of Computational Biomedicine is utilizing the latest technological advances to find solutions to some of the most complex healthcare issues.
Furman chemists receive $1 million grant to create technology to better analyze air particles
Mac Gilliland, assistant professor of chemistry and Mary Elizabeth Anderson, professor of chemistry, will work with engineers and scientists at 908 Devices, a mass spec manufacturer in Boston. At least a dozen Furman undergraduate students will also work on the project, giving them experience in chemistry, device manufacturing and commercialization that few students at undergraduate institutions have.
Killing Cancer in a Flash
FLASH is a targeted radiation therapy that kills tumor cells while sparing healthy tissue and delivers a short, intense burst of radiation in a single appointment. Corie Ralston from Lawrence Berkeley National Laboratory will present her team’s research using X-ray footprinting mass spectrometry to investigate the mechanisms that make FLASH a powerful cancer killer at ACA’s 73rd annual meeting, July 7-11.
Chemists Are on the Hunt for the Other 99 Percent
PNNL scientists are creating new ways to learn more about the vast sea of unknown compounds.
Researchers Use Liquid Chromatography–Mass Spectrometry to Explore Circadian Gene Expression in Mouse Kidneys
Article title: Circadian gene expression in mouse renal proximal tubule Authors: Molly A. Bingham, Kim Neijman, Chin-Rang Yang, Angel Aponte, Angela Mak, Hiroaki Kikuchi, Hyun Jun Jung, Brian G. Poll, Viswanathan Raghuram, Euijung Park, Chung-Lin Chou, Lihe Chen, Jens Leipziger,…
Two meteorites are providing a detailed look into outer space
Meteorites can be used to peek back in time or at the earliest forms of life. Today, scientists report results of the most detailed analyses yet on the organic material of two meteorites. They will present their results at ACS Spring 2023.
Using light to connect molecules
One study, led by the Toker group from Bar-Ilan University in Israel, observed peptide bond formation in clusters containing four serine dipeptides that were heated up by collisions. However, they found no evidence for the same process occurring in serine clusters. In that work they concluded that if two serine molecules can bind together to form a dipeptide, then the next stages of polymerization could probably occur readily.
Harmful Effects of Long-Term Alcohol Use Documented in Blood Protein Snapshot
A detailed snapshot of proteins by PNNL scientists marks a big step toward a diagnostic blood test for a deadly form of liver disease – alcohol-associated hepatitis.
A New Assay Screening Method Shows Therapeutic Promise for Treating Auto-Immune Disease
The January 2023 issue of SLAS Discovery contains a collection of four full-length articles and one technical brief covering cancer research, high-throughput screening (HTS) assay development and other drug discovery exploration.
Scientists use machine learning to get an unprecedented view of small molecules
A new tool to identify small molecules offers benefits for diagnostics, drug discovery, and fundamental research.
Artificial Intelligence in Personalized Medicine, Genomic Sequencing Advances, Human Brain Organogenesis, Building Trust with Patients, Guiding Patient Decisions with Mass Spectrometry, and Much More to Be Explored at 2022 AACC
At the 2022 AACC Annual Scientific Meeting & Clinical Lab Expo, laboratory medicine experts will present the cutting-edge research and technology that is revolutionizing clinical testing and patient care.
SLAS Discovery July Issue Features a New Method of Detecting Metal Impurities in High-Throughput Screening – Available Now
The July issue of SLAS Discovery is now available Open Access on ScienceDirect.
DoD grant for new equipment boosts UAH’s hypersonics fuel research
Scientists at The University of Alabama in Huntsville (UAH), a part of the University of Alabama System, plan to research new fuels for hypersonic vehicles once chromatography/mass spectroscopy equipment arrives later this year at the Propulsion Research Center (PRC).
Tire-related chemical is largely responsible for adult coho salmon deaths in urban streams
A team led by researchers at the University of Washington Tacoma, UW and Washington State University Puyallup have discovered a chemical that kills coho salmon in urban streams before the fish can spawn.
Unraveling the network of molecules that influence COVID-19 severity
Researchers from the Morgridge Institute for Research, the University of Wisconsin-Madison, and Albany Medical College have identified more than 200 molecular features that strongly correlate with COVID-19 severity, offering insight into potential treatment options for those with advanced disease.
October Issue of SLAS Discovery Features Cover Article “A Critical and Concise Review of Mass Spectrometry Applied to Imaging in Drug Discovery”
The October edition of SLAS Discovery features the cover article, “A Critical and Concise Review of Mass Spectrometry Applied to Imaging in Drug Discovery” by Richard J. A. Goodwin Ph.D. (AstraZeneca), Zoltan Takats Ph.D. (Imperial College London), and Josephine Bunch, Ph.D. (National Physical Laboratory).
Technion-developed Method Accelerates Blood Test Analysis by About 98%
A new method for rapid and inexpensive analysis of the chemical composition of blood samples may hasten the early diagnosis of diseases. The first application to be tested will be the early detection of various cancerous tumors based on blood tests.
Identifying the Dark Matter of the Molecular World
Scientists have deployed artificial intelligence to identify more of the billions of metabolites that are currently unknown. The small molecules underlie and inform every aspect of our lives, including energy production, the fate of the planet, and our health. “Beast Mode” helps explain how they did it.
Scientists Discover New Clue Behind Age-Related Diseases and Food Spoilage
Berkeley Lab scientists have made a surprising discovery that could help explain our risk for developing chronic diseases or cancers as we get older, and how our food decomposes over time.
New, Detailed Molecular Roadmap Boosts Fight Against Endometrial Cancer
Scientists have taken an unprecedented look at proteins involved in endometrial cancer, commonly known as uterine cancer. The study offers insights about which patients will need aggressive treatment and which won’t, and offers clues about why a common cancer treatment is not effective with some patients.
Scientists Learn More about the First Hours of a Lithium-ion Battery’s Life
The first hours of a lithium-ion battery’s life largely determine just how well it will perform. In those moments, a set of molecules self-assembles into a structure inside the battery that will affect the battery for years to come. Now scientists have witnessed the formation of the solid-electrolyte interphase at a molecular level.
What’s in Puget Sound? New technique casts a wide net for concerning chemicals
Using a new “non-targeted” approach, University of Washington and UW Tacoma researchers screened samples from multiple regions of Puget Sound to look for potentially harmful compounds that might be present.
An Out-of-the-Box Attack on Diabetes
A protein newly identified as important in type 1 diabetes can delay onset of the disease in diabetic mice, providing a new target for prevention and treatment in people, according to research led by scientists at the U.S. Department of Energy’s Pacific Northwest National Laboratory and Indiana University School of Medicine.