Ketamine is emerging as a powerful tool to treat depression, and other anesthetics such as nitrous oxide (laughing gas) are also showing promise. As the established experts in using these medications to sedate patients during surgery or other procedures, anesthesiologists…
Tag: Ketamine
AANA Issues Updated Practice Considerations for Ketamine Therapy for Psychiatric Disorders and Chronic Pain Management
The American Association of Nurse Anesthesiology (AANA) recently updated its practice considerations addressing ketamine therapy to cite the most current studies, as AANA continues to support a patient-centered, interdisciplinary approach to providing care and treatment to persons with psychiatric disorders or chronic pain.
UC Davis Health opens new clinic for treatment-resistant depression
The Advanced Psychiatric Therapeutics Clinic offers esketamine and transcranial magnetic stimulation (TMS) for patients with treatment-resistant depression.
Ketamine’s promise for severe depression grows, but major questions remain
Using an old anesthesia drug to pull people out of severe depression has gone from fringe idea to widespread use in just a few years.
Ketamine helped many severely depressed veterans, study shows
A new study of data from veterans who had tried many depression treatments but still had severe symptoms suggests a series of intravenous doses of ketamine gave many at least partial relief. For a minority, it led to full remission.
Ketamine’s effect on depression may hinge on hope
In study after study, the psychoactive drug ketamine has given profound and fast relief to many people suffering from severe depression.
Ketamine May Be More Effective in Reducing Postoperative Pain in Patients With a Higher TSP
A study has found that ketamine may be more helpful in preventing postoperative pain among a subset of patients with a higher tendency toward central sensitization as measured by TSP (temporal summation of pain).
Study Shows Ketamine Could Be Beneficial for Treating Brain Injury in Children
A common anesthesia drug could be beneficial in reducing pressure inside the skull of children with traumatic brain injuries (TBI), according to a study published in Critical Care Medicine.
New study reveals ketamine could be effective treatment for cocaine-use disorders
As cocaine use continues to climb across the United States, scientists have struggled to develop an effective pharmacological approach to treat the devastating disorder. But by seamlessly combining artificial intelligence (AI), human intelligence, clinical testing and computer analysis, researchers at Case Western Reserve University have unearthed an existing option that appears to hold promise.
Study Gives Peek of How Ketamine Acts as ‘Switch’ in the Brain
Researchers find that the anesthetic and fast-acting antidepressant switches natural patterns of neuronal activity in the cortex of mice
Drugs Effects of Ketamine in Mice can Depend on the Sex of the Human Experimenter
Researchers at the University of Maryland School of Medicine have shown that mice respond more to the antidepressant effects of the drug ketamine when administered by men and not by women. The group demonstrated that a stress response detected in the mouse’s brain from handling by a man is essential for ketamine to work.
Psychiatrists disagree with U.S. policy on psychoactive drugs
A new national survey reveals considerable differences between psychiatrists’ perceptions about the safety and therapeutic value of certain psychoactive drugs and how those same drugs are categorized under U.S. policy.
EMS Ketamine Use on Agitated Patients on Cocaine Increases Intubation 5.75-fold
Patients with excited delirium often are administered ketamine by EMS before arriving at the hospital. Many of them are intoxicated or are using illicit substances, which may alter the properties of ketamine.
No adverse cognitive effects of ketamine or esketamine for treatment-resistant depression
Used for the treatment of depression that does not respond to standard antidepressant medications, the anesthesia drug ketamine – and the related drug esketamine, recently approved for depression treatment – has no important adverse effects on memory, attention, or other cognitive processes, concludes a systematic review of medical research in the September/October issue of Harvard Review of Psychiatry. The journal is published in the Lippincott portfolio by Wolters Kluwer.
New Findings on How Ketamine Prevents Depression
The discovery that the anaesthetic ketamine can help people with severe depression has raised hopes of finding new treatment options for the disease.
Low doses of “laughing gas” could be fast acting, highly effective treatment for severe depression
A new study at the University of Chicago Medicine and Washington University found that a single inhalation session with 25% nitrous oxide gas was nearly as effective as 50% nitrous oxide at rapidly relieving symptoms of treatment-resistant depression, with fewer adverse side effects.
Repeated Ketamine Infusions Reduce Symptom Severity in Individuals With Chronic Post-Traumatic Stress Disorder
Study offers a key finding in the development of a promising treatment
New study finds antidepressant drug effective in treating “lazy eye” in adults
In a new study, published in Current Biology, researchers from the University of California, Irvine School of Medicine reveal how subanesthetic ketamine, which is used for pain management and as an antidepressant in humans, is effective in treating adult amblyopia, a brain disorder commonly known as “lazy eye.”
Use of Ketamine for a Non-medical Purpose: Statement from the American Society of Anesthesiologists
The American Society of Anesthesiologists firmly opposes the use of ketamine or any other sedative/hypnotic agent to chemically incapacitate someone for a law enforcement purpose and not for a legitimate medical reason. Ketamine is a potent analgesic, sedative and general anesthetic agent which can elevate blood pressure and heart rate, and can lead to confusion, agitation, delirium, and hallucinations. These effects can end in death when administered in a non-health care setting without appropriately trained medical personnel and necessary equipment.
Seaver Autism Center For Research and Treatment at Mount Sinai Launches First Drug Trial for ADNP Syndrome
Researchers at the Seaver Autism Center for Research and Treatment at Mount Sinai have started recruiting participants for a new clinical trial to evaluate the safety, tolerability, and efficacy of a low dose of ketamine in children diagnosed with ADNP syndrome (also known as Helsmoortel-VanDerAa syndrome), a rare neurodevelopmental disorder caused by mutations in the activity dependent neuroprotective protein (ADNP) gene.
SINK COVID-19 study: Can common drugs offer 2-step approach to combat deadly virus?
Researchers at Beaumont Health have begun enrolling patients in a new clinical study aimed at treating COVID-19 patients with two common drugs.
Ketamine Use is Underreported—Likely Due to Unknown Exposure—Among EDM Partygoers
Nearly 37 percent of electronic dance music (EDM) party attendees test positive for ketamine use when samples of their hair are tested—despite only 14.6 percent disclosing that they have used the drug in the past year.
Giving Ketamine Repeatedly for Migraine and Pain Not Associated with Increased Adverse Events
Researchers at Thomas Jefferson University and the University of Virginia retrospectively analyzed patient records see if side effects increased after repeated infusions. They actually found a couple of benefits.