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UrduResearch summary from the Journal of the American Geriatrics Society
Tag: GERONTOLOGY
Frailty: The rising global health burden for an aging society
October 15, 2019 — Despite the evidence on risk factors for frailty, and the substantial progress that has been made in frailty awareness, the biological mechanisms underlying its development are still far from understood and translation from research to clinical…
Meeting of nation’s top health leaders and scholars — Oct. 21
Artificial intelligence in health care, healthy longevity, and human genome editing among topics at meeting of nation’s top health leaders and scholars — Oct. 21
Habitual tea drinking modulates brain efficiency: Evidence from brain connectivity evaluation
The researchers recruited healthy older participants to two groups according to their history of tea drinking frequency and investigated both functional and structural networks to reveal the role of tea drinking on brain organization.
Overcoming the blood-brain-barrier: Delivering therapeutics to the brain
For the first time, scientists have identified a simple way that can effectively transport medication into the brain – which could lead to improved treatments for neurological and neurodegenerative diseases. In a study published today in Nature Communications , scientists…
Slower walkers have older brains and bodies at 45
Retrospective analysis shows the slower walkers could have been identified by brain function at age 3
Adipogenic progenitors keep muscle stem cells young
In adult skeletal muscle, loss of myofiber integrity caused by mechanical injuries or diseases are repaired by resident muscle stem cells, called satellite cells, which promptly exit from quiescence after disruption of muscle architecture to expand, diffe
Conclusions from a behavioral aging study on male and female F2 hybrid mice on age-related behavior
Due to strain-specific behavioral idiosyncrasies, inbred mouse strains are suboptimal research models for behavioral aging studies.
With AGS CoCare: Help, AGS expands reach of seminal delirium prevention program
A seminal program for preventing delirium (the medical term for abrupt, rapid-onset confusion or altered mental state, affecting millions of older adults annually) and loss of function for hospitalized older adults stands poised for a major expansion thanks to the…
Scientists at the MDI biological laboratory are decoding the genetic mechanisms of aging
Discoveries could one day lead to new drugs to prolong healthy human lifespan
New Diagnostic Criteria May Enable Earlier Detection of Cognitive Impairment in Women
Study finds when verbal memory test cut-offs were tailored to patient sex, more female patients and fewer male patients were considered to have amnesic mild cognitive impairment. This could change the way aMCI diagnoses are determined and make it easier to catch the condition in its early stages.
New study supports nervous system’s role in age-related weakness
A study recently published by researchers from the Ohio Musculoskeletal and Neurological Institute (OMNI) at the Ohio University Heritage College of Osteopathic Medicine, in collaboration with a colleague from outside Ohio University, finds new evidence to support the belief that…
AFAR to lead national program office of new Clin-STAR coordinating center of the NIA
Led by AFAR, Johns Hopkins, UCSF, and Yale, Clin-STAR will synergize career development of clinician-investigators across specialties and disciplines to improve care of older adults
Tau-mediated RNA splicing errors linked to Alzheimer’s disease
A collaborative study published today in the journal Cell Reports provides evidence for a new molecular cause for neurodegeneration in Alzheimer’s disease. The study, led by researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research…
Safe and efficient tool to reduce seniors’ medication overload
A study shows that MedSafer, an electronic decision-support tool developed by RI-MUHC researchers, helps reduce inappropriate medications prescribed to the elderly
$2.8 Million Grant Will Fund Preclinical Study of New Dementia Treatment
LEXINGTON, Ky. (Oct. 7, 2019) — The Sanders-Brown Center on Aging has received a five-year, $2.8 million grant to underwrite preclinical efficacy studies of a potential new treatment for dementia. The drug candidate, called MW150, targets dysregulated brain inflammation driven…
Winners announced for National Institute on Aging dementia care coordination challenge
NIA’s Eureka competition awards focus on mobile apps for people with dementia, healthcare providers and caregivers
Experts call for coordinated action to avert a brain disease crisis
Experts are calling for a public health campaign aimed at promoting a ‘brain-healthy lifestyle’ to reduce the risk of developing neurodegenerative brain diseases, such as Alzheimer’s disease and Parkinson’s disease. The campaign should support existing health promotion work by emphasising…
Poor health more likely to be associated with shorter sleep in older Irish population
Trinity College Dublin researchers have shown that some Irish adults are not ‘getting a good night’s sleep’ resulting in an increased risk of negative health outcomes. The first findings on sleep duration in the older Irish population are published by…
Chair yoga more effective than music therapy in older adults with advanced dementia
Pilot study first to show adults with advanced dementia can participate in non-pharmacological interventions
Recommendations to prevent secondary fractures in adults 65+ with osteoporosis
Coalition recommendations target health care professionals who care for older adults at risk for osteoporotic fractures
Inadequate control of thyroid hormones sensitizes to hepatocarcinogenesis and unhealthy aging
The cover features Figure 7 ‘Schematic representation of the effects of the modulation of THs levels in healthspan and lifespan in mice’ from López-Noriega et al
Can humans exploit the genetics of a mouse that regrows axons after injury?
A Transformative Research Award to the Buck Institute from the NIH focuses on a new method to pinpoint genetic differences between species
Geriatrics experts on gender equity in health care: ‘When women rise, we all rise’
Putting power and potential behind gender equity in health care isn’t just common sense. It’s critical to the future of health, safety, and independence for us all as we age, so says the American Geriatrics Society (AGS) in a new…
Cheap, quick test identifies pneumonia patients at risk of respiratory failure or sepsis
Madrid, Spain: Spanish researchers in Valencia have identified specific fragments of genetic material that play a role in the development of respiratory failure and sepsis in pneumonia patients. Presenting the research at the European Respiratory Society International Congress [1] today…
Discovered: Possible therapeutic target for slow healing of aged muscles
New work could reveal a potential pathway for therapeutic targeting to combat muscle degeneration in the elderly
Fruit flies live longer with combination drug treatment
A triple drug combination has been used to extend the lifespan of fruit flies by 48% in a new study led by UCL and the Max Planck Institute for Biology of Ageing. The three drugs are all already in use…
Monthly phone check-in may mean less depression for families of patients with dementia
Fewer trips to ER when caregivers have better access to experts, UCSF study shows
Common nutrient supplementation may hold the answers to combatting Alzheimer’s disease
In a new study, Biodesign researchers reveal that a lifelong dietary regimen of choline holds the potential to prevent Alzheimer’s disease (AD). Choline is a safe and easy-to-administer nutrient that is naturally present in some foods and can be used…
Cause of antibiotic resistance identified
Scientists have confirmed for the first time that bacteria can change form to avoid being detected by antibiotics in the human body. Studying samples from elderly patients with recurring urinary tract infections, the Newcastle University team used state-of-the art techniques…
New genes identified in hearing loss, providing treatment hope
A new study published today in The American Journal of Human Genetics has identified 44 genes linked to age-related hearing loss giving a much clearer understanding of how the condition develops and potential treatments. In the study, researchers from King’s…
Cellular senescence is associated with age-related blood clots
Cells that become senescent irrevocably stop dividing under stress, spewing out a mix of inflammatory proteins that lead to chronic inflammation as more and more of the cells accumulate over time. Publishing in the September 24 edition of Cell Reports…
Latest issue of Alzheimer’s & Dementia
September 2019 journal digest
Microbiome may be involved in mechanisms related to muscle strength in older adults
Study identifies differences in gut microbiome composition in physically high-functioning vs low-functioning older adults, successfully transfers some of these effects into mice
14 journalists earn aging-focused reporting fellowships
The Gerontological Society of America (GSA) and Journalists Network on Generations are welcoming 14 distinguished reporters for the next cohort of the Journalists in Aging Fellows Program , now in its 10th year. They represent a wide range of general…
Improving care for an aging population
UTA receives significant philanthropic gift to further excellence in adult gerontology
What multilingual nuns can tell us about dementia
A strong ability in languages may help reduce the risk of developing dementia, says a new University of Waterloo study. The research, led by Suzanne Tyas, a public health professor at Waterloo, examined the health outcomes of 325 Roman Catholic…
Introducing ‘phyjama,’ a physiological-sensing pajama
UMass Amherst materials chemists, computer scientists introduce smart sleepwear at International Wea
Academics call for structured drug monitoring in care homes
A structured approach to medicine monitoring leads to positive impacts on patients
RRI senior scientist elected as a fellow of the Royal Society of Canada
Dr. Cheryl Grady, a senior scientist at Baycrest’s Rotman Research Institute (RRI), has been recogni
Brain changes may help track dementia, even before diagnosis
MINNEAPOLIS – Even before a dementia diagnosis, people with mild cognitive impairment may have different changes in the brain depending on what type of dementia they have, according to a study published in the September 11, 2019, online issue of…
$53.4M grant to Brown, Hebrew SeniorLife to enable expansion of Alzheimer’s research
Federal grant from the National Institute on Aging will fund a collaborative research incubator to s
Researchers propose the ‘Alzheimer’s Disease Exposome’ to address environmental risks
USC and Duke researchers say the framework illustrates how environmental and genetic factors interac
Study links hearing aids to lower risk of dementia, depression and falls
Study of Medicare HMO participants, whose insurance covers part of hearing aid cost, reveals dispari
Penn researcher Virginia M.Y. Lee, Ph.D., receives $3 million breakthrough prize
Award recognizes Lee’s work studying underlying mechanisms of neurodegenerative diseases
Hearing aids may help reduce risks of dementia, depression, and falls
Use of hearing aids was linked with lower risks of being diagnosed with Alzheimer’s disease, dementia, depression, anxiety, and injurious falls in an analysis of medical information on 114,862 older adults with hearing loss. The findings are published in the…
Migraines linked to higher risk of dementia
Dementia is the most common neurological disease in older adults, whereas headaches, including migraines, are the most common neurological disorder across all ages. In a recent study in the International Journal of Geriatric Psychiatry that included 679 community-dwelling adults aged…
Michael A. Petr to present at the 6th Annual Aging Research, Drug Discovery, and AI Forum in Basel
Thursday, September 5, 2019 – Today the Biogerontology Research Foundation , a leading UK non-profit foundation dedicated to increasing healthy longevity and promoting advances in ageing research, Insilico Medicine , a biotechnology company developing the end-to-end drug discovery pipeline utilizing…
Vast majority of dementia patients don’t receive specialty diagnosis and care, study finds
Researchers found the use of dementia specialty care is particularly low for Hispanics and Asians
Ageing research to accelerate with experimental validation in AI-powered drug discovery
Biogerontology Research Foundation scientists have developed and experimentally-validated a new AI e