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UrduA new UCLA-led study has identified multiple new risk genes for Alzheimer’s disease and a rare, related brain disorder by using a combination of new testing methods allowing for mass screening of genetic variants in a single experiment.
Tag: Drug Target
Blocking enzyme could hold the key to preventing, treating severe COVID-19
Blocking an immune response-related enzyme holds promise in preventing or treating severe COVID-19 symptoms by reducing inflammation, tissue injury and blood clots in the lungs, new research in mice suggests.
Pioneering software can grow and treat virtual tumours using AI designed nanoparticles
The EVONANO platform allows scientists to grow virtual tumours and use artificial intelligence to automatically optimise the design of nanoparticles to treat them.
Research reveals drug targets for memory enhancement
Bristol-led research has identified specific drug targets within the neural circuits that encode memories, paving the way for significant advances in the treatment of a broad spectrum of brain disorders.
Heart Cell Protein Could Lead to New Treatments for Heart Failure and Recovery
A protein that helps regulate calcium signaling within heart cells could play a key role in preventing chronic heart failure, according to an international study led by University of Utah Health scientists. T The finding suggests that drugs and other therapeutic treatments targeting this protein could eventually help alleviate heart failure.
Astrocytes offer potential drug targets for Huntington’s disease
UCLA scientists discovered that astrocytes, a cell type long implicated in brain diseases, is remarkably malleable and shows responses in a mouse model that suggest potential targets for drugs for Huntington’s disease.
Breakthrough led by NUS researchers provides new potential therapies for osteoporosis
Researchers from the National University of Singapore have identified a new avenue to maintain bone health, which opens up new and potentially more effective osteoporosis treatments.
Scientists discover novel drug target for pancreatic cancer
Scientists at Sanford Burnham Prebys Medical Discovery Institute have uncovered a novel drug target, a protein called PPP1R1B, that stops the deadly spread of pancreatic cancer, called metastasis, when inhibited in mice. Published in Gastroenterology, the findings are a first step toward a potential treatment for one of the deadliest cancers known today.
Researchers identify new therapeutic target for colorectal cancer
Researchers at the University of Toronto have identified a key protein that supports the growth of many colorectal cancers. The study, which will be published December 27 in the Journal of Cell Biology, reveals that a protein called Importin-11 transports the cancer-causing protein βcatenin into the nucleus of colon cancer cells, where it can drive cell proliferation. Inhibiting this transport step could block the growth of most colorectal cancers caused by elevated βcatenin levels.