Rothman Orthopaedic Institute Foundation to Host Symposium on Xylazine Crisis in Pennsylvania

The Rothman Orthopaedic Institute Foundation for Opioid Research & Education announces a symposium titled “The Next Chapter of the Opioid Epidemic in Pennsylvania: The Xylazine Crisis” to be held on November 23, 2024, from 8:30 am to 12:30 pm at the Bluemle Life Science Building at Jefferson Med in Philadelphia.

A Common Pathway in the Brain That Enables Addictive Drugs to Hijack Natural Reward Processing Has Been Identified by Mount Sinai

Mount Sinai researchers, in collaboration with scientists at The Rockefeller University, have uncovered a mechanism in the brain that allows cocaine and morphine to take over natural reward processing systems.

Offering medications for opioid addiction to incarcerated individuals leads to decrease in overdose deaths

New research from Boston Medical Center concluded that offering medications to treat opioid addiction in jails and prisons leads to a decrease in overdose deaths. Published in JAMA Network Open, the study also found that treating opioid addiction during incarceration is cost-effective in terms of healthcare costs, incarceration costs, and deaths avoided.

New Study Suggests Healthcare Provider Biases Can Impact a Patient’s Access to Preventative HIV Drug

A new study published today reveals systematic biases among primary and HIV care providers about people who inject drugs and how those biases may impact access to pre-exposure prophylaxis (PrEP), a preventive, prescription-based medication that significantly reduces the risk of HIV infection through sexual behavior and injection practices.

Mechanisms of addiction: Psychology professor receives NIH grant for brain research

A five-year, $2.59 million grant from the National Institutes of Health will allow a psychology professor at Binghamton University, State University of New York to study the mechanisms of addiction.

Initiative to Get COVID-19 Vaccines to People with Substance Use Disorder Launched by Addiction Policy Forum (APF) and Foundation for Opioid Response Efforts (FORE)

The Foundation for Opioid Response Efforts (FORE) and the Addiction Policy Forum (APF) are launching a program to assist people with substance use disorder obtain COVID-19 vaccinations.

Research News Tip Sheet: Story Ideas from Johns Hopkins Medicine

During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Wednesday.

Novel Anti-Craving Mechanism Discovered to Treat Cocaine Relapse

Cocaine continues to be one of the most commonly abused illicit drugs in the United States. Pre-clinical literature suggests that targeting glucagon-like peptide-1 receptors (GLP-1Rs) in the brain may represent a novel approach to treating cocaine use disorder. Specifically, GLP-1R agonists, which are FDA-approved for treating diabetes and obesity, have been shown to reduce voluntary drug taking and seeking in preclinical models of cocaine used disorder. However, the exact neural circuits and cell types that mediate the suppressive effects of GLP-1R agonists on cocaine-seeking behavior are mostly unknown.

Negative side effects of opioids could be coming from users’ own immune systems (video)

Opioid users can develop chronic inflammation and heightened pain sensitivity. These side effects might stem from the body’s own immune system, which can make antibodies against the drugs. The researchers will present their results at the American Chemical Society Fall 2020 Virtual Meeting & Expo.