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UrduResearchers at UC San Diego identify a key pathway leading to neurodegeneration in early stages of ALS, hinting at the potential for short-circuiting the progression of the fatal disease if diagnosed early.
Tag: Amyotrophic Lateral Sclerosis
Mayo Clinic awarded federal grant to study experimental ALS drug
Mayo Clinic in Florida has received a grant from the National Institute of Neurological Disorders and Stroke (NIDS) to begin an innovative study that will provide hundreds of patients with amyotrophic lateral sclerosis (ALS) access to the experimental drug ibudilast over six months.
Ileana Howard, MD, Selected to Speak at the 2024 AANEM Annual Meeting
The American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM), is excited to announce Ileana Howard, MD, as a plenary speaker at the 2024 AANEM Annual Meeting Oct. 15-18, in Savannah, Georgia.
Q&A: New Frontiers in ALS Research
Clive Svendsen, PhD, executive director of the Board of Governors Regenerative Medicine Institute and professor of Medicine and Biomedical Sciences at Cedars-Sinai, is developing new treatments and models for amyotrophic lateral sclerosis (ALS) using stem cells.
Chemicals stored in home garages linked to ALS risk
Storing chemicals in a garage at home may associate with an increased risk of ALS, a study finds. This comes as research has found that exposure to environmental toxins, such as pesticides and volatile organic compounds, are also linked to ALS development. Researchers call the buildup of exposures of the lifetime the ALS exposome.
Recreational activities such as golfing, gardening may be associated with increased ALS risk among men
Participation in recreational activities — including golfing, gardening or yard work, woodworking and hunting — may be associated with an increase in a person’s risk for developing ALS.
Gold nanoparticles reverse brain deficits in multiple sclerosis, Parkinson’s
Results from phase two clinical trials at UT Southwestern Medical Center showed that a suspension of gold nanocrystals taken daily by patients with multiple sclerosis (MS) and Parkinson’s disease (PD) significantly reversed deficits of metabolites linked to energy activity in the brain and resulted in functional improvements.
Ohio State researchers publish national guidelines for ALS genetic testing, counseling
Researchers at The Ohio State University Wexner Medical Center and led the creation of evidence-based consensus guidelines for genetic testing and counseling for patients with amyotrophic lateral sclerosis (ALS), a neurodegenerative disease that affects the cells in the brain and spine.
Brooke Eby Receives AANEM’s 2023 Public Recognition Award for ALS Advocacy Efforts
The American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM) proudly announces Brooke Eby as the 2023 Public Recognition Award recipient for her remarkable commitment to raising awareness about muscle and nerve disorders, specifically amyotrophic lateral sclerosis (ALS).
ALS Center Celebrates Opening of New Practice Office
Hackensack Meridian Neuroscience Institute at Jersey Shore University Medical Center recently celebrated the opening of the ALS Center’s new office in the Dr. Robert H. Harris Neuroscience Treatment Center. The center is one of only two Certified Treatment Centers of Excellence in New Jersey and is designated by the ALS Association’s National Office and the Greater Philadelphia Chapter.
$10 million gift to support ALS research, educational outreach at local high schools
The University of Chicago has received a $10 million gift from the Lohengrin Foundation to help establish a center of excellence in research on amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. ALS and its related conditions are devastating neurological diseases. Also known as Lou Gehrig’s disease, ALS progressively destroys nerve cells that control body movements, and affects as many as 30,000 Americans each year.
ALS risk higher among production workers, those exposed to metals, volatile compounds on job
A new study finds people working in “production” – fields such as manufacturing, welding and chemical operation – who are exposed to hazardous chemicals on the job, may have increased risk of developing ALS. People with ALS report higher occupational exposure to metals, particulate matter, volatile organic compounds and combustion pollutants prior to diagnosis.
Stem Cell-Gene Therapy Shows Promise in ALS Safety Trial
Cedars-Sinai investigators have developed an investigational therapy using support cells and a protective protein that can be delivered past the blood-brain barrier. This combined stem cell and gene therapy can potentially protect diseased motor neurons in the spinal cord of patients with amyotrophic lateral sclerosis, a fatal neurological disorder known as ALS or Lou Gehrig’s disease.
Gene Therapy Approach Shows Promise in Treating ALS
Researchers report that a gene therapy approach, developed at UC San Diego measurably delayed disease onset in humanized mouse and rat models of familial ALS, an inherited form of the disease that runs in families.
Mount Sinai Researchers Learn That ALS May Be Linked to Both the Immune and Central Nervous Systems
New York, NY (June 22, 2022) – The immune system may play a fundamental role along with the central nervous system in amyotrophic lateral sclerosis (ALS), also known as “Lou Gehrig’s disease,” Mount Sinai researchers report. Their study, published…
UIC researchers find evidence of possible link between herpes simplex and neurogenerative diseases
A new study by researchers at University of Illinois Chicago suggests that when the protein optineurin, or OPTN, is present in cells it restricts the spread of HSV-1, the herpes simplex virus type 1.In a “first of its kind” study, researchers also found a potential direct connection between neurodegenerative diseases, such as Alzheimer’s disease, amyotrophic lateral sclerosis (ALS), glaucoma, and the herpesvirus.
Hopkins Med News Update
NEWS STORIES IN THIS ISSUE:
-Study: Race and Ethnicity May Impact Prevalence and Treatment of Heart Valve Dysfunction
-Johns Hopkins Medicine Suggests Eliminating Nerve Cell Protein May Stop ALS, Dementia
-Researchers Tell Doctors to Avoid Routine Urinary Tests for Older Patients with Delirium
-Johns Hopkins Medicine Researchers Show How Air Pollution May Cause Chronic Sinusitis
-Researchers ID Location on Brain Protein Linked to Parkinson’s Disease Development
-COVID-19 News: The Return of Onsite Schooling — and How to Keep Your Kids Safe from COVID
ALS: Study Shows Role of Brain’s Immune Cells
Hyperactive immune cells in the brain may play a role in the early development of the neurodegenerative disease Amyotrophic lateral sclerosis (ALS), and a form of dementia that strikes younger people, according to a study conducted by investigators from Cedars-Sinai and published in the journal Neuron.
Scientists Discover Cellular Stress Enzyme That Might Play Key Role in Neurodegenerative Diseases Such as ALS
An enzyme called MARK2 has been identified as a key stress-response switch in cells in a study by researchers at Johns Hopkins Bloomberg School of Public Health.
UChicago scientists design stretchable electronics, perform better under strain
Recent technological advances have made stretchable sensors possible, but their changes in shape can affect the data produced, and many sensors cannot collect and process the body’s faintest signals. A new sensor design from the Pritzker School of Molecular Engineering (PME) at the University of Chicago helps solve that problem.
Washington University School of Medicine in St. Louis NEWS RELEASE Embargoed until 5 p.m. ET Wednesday, July 8, 2020 Experimental drug shows early promise against inherited form of ALS, trial indicates
A clinical trial conducted at Washington University School of Medicine in St. Louis and other sites has found evidence that the experimental drug tofersen lowers levels of a disease-causing protein in people with an inherited form of amyotrophic lateral sclerosis, or ALS, caused by mutations in the gene SOD1.