Alzheimer’s Association and Rainwater Charitable Foundation continue efforts to accelerate drug discovery focused on a toxic brain protein that leads to the death of brain cells
Tag: Alzheimer’s Disease
Bilingualism acts as a cognitive reserve factor against dementia
According to a study led jointly by researchers from the Speech Production and Bilingualism group at the UPF Cognition and Brain Center and the Functional Neuropsychology and Neuroimaging research group at the Jaume I University of Castellón.
Bilingualism acts as a cognitive reserve factor against dementia
According to a study led jointly by researchers from the Speech Production and Bilingualism group at the UPF Cognition and Brain Center and the Functional Neuropsychology and Neuroimaging research group at the Jaume I University of Castellón.
Nearly $4m in research funding for promising new treatments in Alzheimer’s, other dementia
Alzheimer’s Association and Rainwater Charitable Foundation continue efforts to accelerate drug discovery focused on a toxic brain protein that leads to the death of brain cells
Gene variants may increase susceptibility to accumulate Alzheimer’s protein tau, study shows
The toxic protein tau is a key biological feature in the brains of people with Alzheimer’s disease. Yet the factors that make people susceptible or resistant to tau accumulation are not well-understood. A preliminary Mayo Clinic study shows that inherited DNA variants may be associated with developing tau deposits in older adults. The research will be presented at the American Academy of Neurology’s 72nd Annual Meeting in Toronto April 25–May 1.
Visceral fat delivers signal to the brain that hurts cognition
Excessive weight around our middle gives our brain’s resident immune cells heavy exposure to a signal that turns them against us, setting in motion a crescendo of inflammation that damages cognition, scientists say. It’s known this visceral adiposity, characterized by…
Researchers find gene variants that may increase susceptibility to Alzheimer’s proteins
MINNEAPOLIS – Researchers know that the protein tau develops into tangles in the brains of people with Alzheimer’s disease. But until now they have struggled to understand what factors make you more or less likely to develop these tangles. In…
Alzheimer’s: Can an amino acid help to restore memories?
Scientists at the Laboratoire des Maladies Neurodégénératives (CNRS/CEA/Université Paris-Saclay) and the Neurocentre Magendie (INSERM/Université de Bordeaux) have just shown that a metabolic pathway plays a determining role in Alzheimer’s disease’s memory problems. This work, published on 3 March 2020 in…
Gene variants may increase susceptibility to accumulate Alzheimer’s protein tau
ROCHESTER, Minn. — The toxic protein tau is a key biological feature in the brains of people with Alzheimer’s disease. Yet the factors that make people susceptible or resistant to tau accumulation are not well-understood. A preliminary Mayo Clinic study…
Coordination chemistry and Alzheimer’s disease
Mechanistic approaches to chemically modify neurotoxicity of Alzheimer’s disease
‘Brain Surfing’: Ultrasound waves focused on prefrontal cortex elevate mood and change brain connectivity in human volunteers
A team of researchers at the University of Arizona has found that low-intensity ultrasound waves directed at a particular region of the brain’s prefrontal cortex in healthy subjects can elevate mood, and decrease connectivity in a brain network that has been shown to be hyperactive in psychiatric disorders. The method uses transcranial focused ultrasound (‘tFUS’), a painless, non-invasive technique to modulate brain function comparable to transcranial magnetic stimulation (‘TMS’), and transcranial direct current stimulation (‘tDCS’). This study shows, for the first time, a correlation between tFUS-induced mood enhancement, and reorganization of brain circuits.
Could targeting an Alzheimer’s-associated protein prevent Autism?
New study shows reducing levels of the protein tau prevents core autism symptoms in animal models
Could targeting an Alzheimer’s-associated protein prevent Autism?
New study shows reducing levels of the protein tau prevents core autism symptoms in animal models
Blood test method may predict Alzheimer’s protein deposits in brain
NIH-funded study reports advance in blood-based detection of ptau181, a biomarker of Alzheimer’s disease
Blood test method may predict Alzheimer’s protein deposits in brain
NIH-funded study reports advance in blood-based detection of ptau181, a biomarker of Alzheimer’s disease
Scientists find functioning amyloid in healthy brain
Researchers at the Department of Genetics and Biotechnology of St Petersburg University have discovered a functioning amyloid in a healthy brain.
Scientists find functioning amyloid in healthy brain
Researchers at the Department of Genetics and Biotechnology of St Petersburg University have discovered a functioning amyloid in a healthy brain.
Memory concerns? Blood test may put mind at ease or pave way to promising treatments
Plasma marker may flag Alzheimer’s as cause of mild cognitive impairment, UCSF-led study shows
Memory concerns? Blood test may put mind at ease or pave way to promising treatments
Plasma marker may flag Alzheimer’s as cause of mild cognitive impairment, UCSF-led study shows
Gene therapy generates new neurons to treat Huntington’s disease
Gene therapy to treat Huntington’s disease
Two sides of a coin: Our own immune cells damage the integrity of the blood-brain barrier
The blood-brain barrier is a layer of cells that covers the blood vessels in the brain and regulates the entry of molecules from the blood into the brain. Increases in blood-brain barrier “permeability,” or the extent to which molecules leak…
Revving habits up and down, new insight into how the brain forms habits
Each day, humans and animals rely on habits to complete routine tasks such as eating and sleeping. As new habits are formed, this enables us to do things automatically without thinking. As the brain starts to develop a new habit,…
Could new discovery play a role in diagnosing Alzheimer’s earlier?
Discovered in mice and confirmed in human samples, scientific team become the first to observe how a characteristic of the Presenilin1 gene means it could be used as a biomarker for Alzheimer’s
Revving habits up and down, new insight into how the brain forms habits
Each day, humans and animals rely on habits to complete routine tasks such as eating and sleeping. As new habits are formed, this enables us to do things automatically without thinking. As the brain starts to develop a new habit,…
Could new discovery play a role in diagnosing Alzheimer’s earlier?
Discovered in mice and confirmed in human samples, scientific team become the first to observe how a characteristic of the Presenilin1 gene means it could be used as a biomarker for Alzheimer’s
New research uncovers potential pathway to slowing Alzheimer’s
The study explores the loss of RNA editing, a genetic mechanism important in creating connections between nerve cells in the brain.
Does smoking increase your risk for dementia and cognitive decline?
Scientists from the Uniformed Services University (USU), Emory University and the University of Vermont have found that cigarette smoking is linked to increased lesions in the brain’s white matter, called white matter hyperintensities. White matter hyperintensities, detected by MRI scan, are associated with cognitive decline and Alzheimer’s disease. These findings may help explain the link between smoking and increased rates of dementia and other forms of cognitive decline.
Scientists Discover New Clue Behind Age-Related Diseases and Food Spoilage
Berkeley Lab scientists have made a surprising discovery that could help explain our risk for developing chronic diseases or cancers as we get older, and how our food decomposes over time.
ADDF statement on the USPSTF Evidence Report on screening for cognitive impairment
Patients with Alzheimer’s and their families deserve and need early detection, early diagnosis, care and treatment
Researchers identify novel anti-aging targets
A recent study published in Nature has reported two conserved epigenetic regulators as novel anti-aging targets. The research, by scientists from Dr. CAI Shiqing’s Lab at the Center for Excellence in Brain Science and Intelligence Technology, Institute of Neuroscience of…
Hearing aids may delay cognitive decline, research finds
Wearing hearing aids may delay cognitive decline in older adults and improve brain function, according to promising new research
ADDF statement on the USPSTF Evidence Report on screening for cognitive impairment
Patients with Alzheimer’s and their families deserve and need early detection, early diagnosis, care and treatment
Researchers identify novel anti-aging targets
A recent study published in Nature has reported two conserved epigenetic regulators as novel anti-aging targets. The research, by scientists from Dr. CAI Shiqing’s Lab at the Center for Excellence in Brain Science and Intelligence Technology, Institute of Neuroscience of…
Hearing aids may delay cognitive decline, research finds
Wearing hearing aids may delay cognitive decline in older adults and improve brain function, according to promising new research
Temple’s Dr. Silvia Fossati awarded $500,000 grant for Alzheimer’s drug discovery research
(Philadelphia, PA) – Silvia Fossati, PhD, Associate Professor of Pharmacology and Associate Director of the Alzheimer’s Center at Temple at the Lewis Katz School of Medicine, has been awarded a two-year $500,000 grant from The Edward N. and Della L.…
Temple’s Dr. Silvia Fossati awarded $500,000 grant for Alzheimer’s drug discovery research
(Philadelphia, PA) – Silvia Fossati, PhD, Associate Professor of Pharmacology and Associate Director of the Alzheimer’s Center at Temple at the Lewis Katz School of Medicine, has been awarded a two-year $500,000 grant from The Edward N. and Della L.…
Two grants will fund research into neurotechnology, drug delivery system
Two grants will fund interdisciplinary research, including a look at how neurons and muscle cells communicate with each other and also to develop a drug delivery system for treatment of Alzheimer’s disease.
Neighborhood Features and One’s Genetic Makeup Interact to Affect Cognitive Function
FAU Study First to Examine How Neighborhood Environment Affects Cognition Based on One’s Genetic Risk for Alzheimer’s, Dementia
One drug, many diseases
It seems too good to be true: a single drug that could treat humanity’s worst afflictions, including atherosclerosis, cancer, Alzheimer’s, Parkinson’s and arthritis. All of these diseases have one thing in common — they involve an inflammatory protein called NLRP3.…
Right place, right time
Harvard researchers shed light on how the brain and its arteries communicate to supply blood to areas of heightened neural activity
Right place, right time
Harvard researchers shed light on how the brain and its arteries communicate to supply blood to areas of heightened neural activity
Researchers discover how cells clear misfolded proteins from tissues
Researchers in Japan have identified a new quality control system that allows cells to remove damaged and potentially toxic proteins from their surroundings. The study, which will be published February 18 in the Journal of Cell Biology, finds that the Clusterin protein and heparan sulfate proteoglycans combine to bring misfolded proteins into cells for degradation. The findings may lead to new therapeutic targets for neurodegenerative disorders, including Alzheimer’s disease.
Despite a marked reduction in the prevalence of dementia, the number of people with dementia is set to double by 2050 according to new Alzheimer Europe report
Brussels, 18 February 2020 – Today, at a European Parliament lunch debate hosted by Christophe Hansen MEP (Luxembourg), Alzheimer Europe launched a new report presenting the findings of its collaborative analysis of recent prevalence studies and setting out updated prevalence…
Subtle decline in cognition predicts progression to Alzheimer’s pathology
Abnormal levels of beta-amyloid plaques in brain predict cognitive decline and higher risk of developing Alzheimer’s disease, but study also finds that cognitive performance predicts progression from normal to abnormal levels of beta-amyloid
Subtle decline in cognition predicts progression to Alzheimer’s pathology
Abnormal levels of beta-amyloid plaques in brain predict cognitive decline and higher risk of developing Alzheimer’s disease, but study also finds that cognitive performance predicts progression from normal to abnormal levels of beta-amyloid
Public lecture on human cooperation, press room, and more: CNS 2020 is 1 month away
27th Annual Meeting of the Cognitive Neuroscience Society
Second South Texas Alzheimer’s Conference convenes Feb. 23-25 in San Antonio
Increasing representation of Hispanics/Latinos in clinical trials among key topics
New Brazilian study describes neural inflammatory processes in lab-developed human cells
Astrogliosis, an inflammation that occurs in the brain tissue, is common to Alzheimer’s and Parkinson’s diseases
Can bilingualism protect the brain even with early stages of dementia?
Researchers find bilingualism provides the brain with greater cognitive reserve, delaying onset of symptoms
Second South Texas Alzheimer’s Conference convenes Feb. 23-25 in San Antonio
Increasing representation of Hispanics/Latinos in clinical trials among key topics