news, journals and articles from all over the world.
The National Academy of Sciences elected two more UT Southwestern Medical Center scientists in the fields of molecular genetics and physiology into its membership, one of the highest honors for American scientists. Russell DeBose-Boyd, Ph.D., Professor of Molecular Genetics, and Duojia Pan, Ph.D., Chair of Physiology and a Howard Hughes Medical Institute Investigator, were elected by their peers in recognition of the importance of their scientific discoveries.
Researchers have long known there are sex disparities when it comes to the prevalence and severity of knee osteoarthritis, a disease that causes cartilage degeneration. Now, investigations underway at UT Southwestern Medical Center point to biological differences in the knee cartilage of male and female animals that could explain substantial variances in rates of osteoarthritis between the sexes and may eventually lead to tailored treatments that take these into account.
The rate of heart attacks, strokes, and other cardiovascular complications increased among patients hospitalized with COVID-19 between March 2020 and December 2021, according to a new study led by UT Southwestern Medical Center researchers. The rise came even as patients hospitalized with the virus tended to be younger and less likely to have had cardiovascular disease (CVD) as the pandemic wore on.
UT Southwestern Medical Center will lead a national multicenter clinical trial to test a treatment strategy for pediatric cancer patients that has shown promising results in adults. The trial will examine the effects of combining several chemotherapy agents with an immunotherapy drug in children with solid tumors that have recurred or shown no significant response after initial treatment.
While rheumatic diseases typically affect the joints, muscles, or ligaments, the first signs of a problem may appear on the skin. A UT Southwestern physician who specializes in rheumatology says it’s essential to know what to look for.
Women with chronic hypertension and diabetes who were enrolled in an award-winning program for 12 months after childbirth were more likely to keep follow-up health care visits, which in turn led to improved care, according to initial findings of the program published in The Joint Commission Journal on Quality and Patient Safety.
A team led by UT Southwestern Medical Center researchers has discovered a protein that appears to be pivotal for traumatic heterotopic ossification (HO), a condition in which bone forms in muscles, tendons, and other soft tissues after traumatic injury or surgery. The findings, published in Science Advances, could yield new ways to prevent this common complication, the researchers say.
Susan Hedayati, M.D., Director of Clinical and Population Health Research in Nephrology at UT Southwestern, has spent a career investigating the links between kidney disease and depression and developing methods to improve care from a patient-centric perspective for those with chronic kidney disease.
New technologies that can capture subtle changes in a patient’s voice may help physicians diagnose cognitive impairment and Alzheimer’s disease before symptoms begin to show, according to a UT Southwestern Medical Center researcher who led a study published in the Alzheimer’s Association publication Diagnosis, Assessment & Disease Monitoring.
Spring marks the arrival of baseball, and with it the risk of elbow injuries among young players. Tears or ruptures of the ulnar collateral ligament (UCL) are the most common elbow injury among baseball players from youth leagues to the major leagues, especially pitchers. The most severe cases require reconstructive surgery, commonly known as Tommy John surgery.
Multiple studies have demonstrated that Black patients are significantly less likely than white patients to undergo invasive cardiovascular procedures. Prior research also has demonstrated substantial racial disparities in the use of implantable cardioverter-defibrillators (ICDs) that can be lifesaving for those at high risk for sudden cardiac death.
About 1 million people in the United States have Parkinson’s disease, a progressive neurological disorder that ranks second to Alzheimer’s among the most common neurodegenerative diseases. While many tend to associate Parkinson’s with hand tremors, it can cause a broad range of symptoms, affecting both motor and nonmotor functions.
Researchers led by a team at UT Southwestern Medical Center have created a statistical model to identify standards for typical, high, or low rates of bleeding after pediatric tonsillectomies. The findings, published in JAMA Otolaryngology-Head & Neck Surgery, could help doctors and hospitals improve outcomes for the third-most common pediatric surgery in the U.S.
After a school shooting like the one that occurred in Nashville, parents may find themselves trying to navigate difficult conversations with their children. What to say is just as important as what not to say, according to experts at UT Southwestern Medical Center. Children are naturally curious and may have questions, or they may be worried about their own safety.
Patients overwhelmingly prefer to receive test results as soon as they are available on online medical portals, even if it means viewing the results prior to discussing them with their doctor, a new study co-led by researchers at UT Southwestern and Vanderbilt University medical centers reports.
Nearly 100% of UT Southwestern Medical School students matched to residency programs – well above the national average of 94% – including about half who matched to hospitals affiliated with U.S. News & World Report’s top 25 medical schools, including UT Southwestern. More than 100 matched to Texas programs.
Ten scientists in the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern Medical Center have been awarded nearly $15 million in grants from the Cancer Prevention and Research Institute of Texas (CPRIT) to advance research on a wide range of cancer issues.
UT Southwestern Medical Center has established the Beth Levine, M.D. Prize in Autophagy Research, an annual award and lecture for exceptional scientists who have made significant contributions to the field of autophagy.
Researchers at UT Southwestern Medical Center have discovered how healthy bacteria can escape the intestine, travel to lymph nodes and cancerous tumors elsewhere in the body, and boost the effectiveness of certain immunotherapy drugs. The findings, published in Science Immunology, shed light on why antibiotics can weaken the effect of immunotherapies and could lead to new cancer treatments.
A shot of a liver-produced hormone called FGF21 sobered up mice that had passed out from alcohol, allowing them to regain consciousness and coordination much faster than those that didn’t receive this treatment, UT Southwestern researchers report in a new study. The findings, published in Cell Metabolism, could lead to effective treatments for acute alcohol intoxication, which is responsible for about 1 million emergency room visits in the U.S. each year.
How estrogen receptor-positive (ER+) breast cancer responds to hormone therapy may hold keys to understanding how it will respond to radiation therapy, and an experimental drug that increases the effectiveness of hormone therapy also overcomes radiation resistance in breast cancer, a study by UT Southwestern Medical Center researchers shows.
Cell membrane protrusions called blebs that typically signify the end of life for healthy cells do the opposite for melanoma cells, activating processes in these cells that help them to survive and spread, a UT Southwestern study suggests.
Business consultant, attorney, and investor Debra Hunter Johnson, founder of Reciprocity Consulting Group, will chair the UT Southwestern Medical Center President’s Advisory Board for the 2023-2025 term.
Researchers at UT Southwestern Medical Center have discovered the first molecular biomarker for acquired generalized lipodystrophy (AGL), a rare disorder in which fat deposits are destroyed, causing patients to have dangerously low body fat, signs of accelerated aging, and severe metabolic diseases including diabetes and fatty liver.
Young adolescents face different challenges in pregnancy compared with their older teenage peers and adults that are sometimes exacerbated by high rates of obesity, a new study by UT Southwestern researchers suggests. The findings, published in the American Journal of Obstetrics & Gynecology MFM, could highlight at-risk populations for targeted prevention efforts.
Technology can be a pain in the neck, leading to what’s known as “tech neck,” chronic pain that results from prolonged use of mobile phones, tablets, and other electronic devices.
UT Southwestern Medical Center researchers have mapped gene control elements in specialized cardiac cells responsible for coordinating heartbeats. The findings of the genome exploration study, published in The Journal of Clinical Investigation, provide insight into how heartbeats are regulated and could impact diagnosis and risk prediction for a variety of common arrhythmias.
The severity of a lung disease associated with e-cigarettes in teens decreased during the COVID-19 pandemic, but hospitalizations from the disease continued to mount, according to a study of more than three dozen patients by UT Southwestern researchers published in Pediatric Pulmonology.
UT Southwestern Medical Center researchers have discovered a method cells use to turn genes on and off that involves portions of proteins whose function has long been a mystery. The findings, reported in Cell, could lead to new ways of controlling gene regulation and may one day lead to new treatments for a broad array of diseases.
A study of retired professional football players by researchers at UT Southwestern Medical Center found that their cognitive abilities did not differ significantly from a control group of similarly aged men who did not play football, nor did those abilities show significant change over one to five years. The findings were published in Brain Injury.
A study by UT Southwestern researchers has identified three factors that increase the risk that bunion surgery will fail to fix this painful foot condition. The findings, published in The Journal of Foot and Ankle Surgery, provide information that surgeons can use to counsel patients considering this elective procedure.
Hepatocellular carcinoma (HCC), the most common type of liver cancer, can place a significant financial burden on patients, according to an analysis led by a researcher at UT Southwestern Medical Center.
UT Southwestern physician-scientist Hesham Sadek, M.D., Ph.D., has received the prestigious National Institutes of Health (NIH) Outstanding Investigator Award to support his ongoing research into mechanisms behind heart regeneration that could lead to treatments for heart failure.
Two of UT Southwestern’s Howard Hughes Medical Institute researchers in biochemistry and molecular biology will lead separate teams as part of HHMI’s Emerging Pathogens Initiative (EPI) targeting infectious diseases that pose a threat to human health.
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