Age, sex, race among top risk factors for revision knee surgery

Patients who are younger than about 40, male, or Black are among those most at risk for revision surgery after having had a total knee replacement, according to researchers at UT Southwestern Medical Center. The study, published in the Archives of Orthopaedic and Trauma Surgery, was the first to explore relationships among risk factors for revision after total knee arthroplasty (TKA).

Male, female knee cartilage disparities may explain differences in rates of degeneration

Researchers have long known there are sex disparities when it comes to the prevalence and severity of knee osteoarthritis, a disease that causes cartilage degeneration. Now, investigations underway at UT Southwestern Medical Center point to biological differences in the knee cartilage of male and female animals that could explain substantial variances in rates of osteoarthritis between the sexes and may eventually lead to tailored treatments that take these into account.