English
Arabic
Chinese (Simplified)
Dutch
Esperanto
French
German
Greek
Italian
Japanese
Korean
Portuguese
Russian
Spanish
UrduIntermittent high dosing regimen for patients with advanced cancers is safe and results in very high concentrations of the drug in the tumor
Tag: Gastroenterology
Vaccine to treat and prevent lung, bowel and pancreatic cancer shows promise in the lab
An experimental vaccine, designed to enlist the body’s own immune system to target cancer cells, has shown promise for treating and preventing cancer in mice. The vaccine was created to target a gene called KRAS that is involved in the…
Discoveries reshape understanding of gut microbiome
Findings could lead to new therapies for IBD and people who’ve had portions of their bowels removed due to conditions like colon cancer and ulcerative colitis
Cutting cancer off at the head
Osaka City University detects cancer cells in 2ml blood samples and connects them back to their origin tumor — creating a new diagnostic tool that may aid in quicker and more accurate anti-cancer measures
More turkey dinners for people with celiac disease?
Researchers find combo of tryptophan with probiotics may help them heal
UArizona Health Sciences researchers find biomarker that can appear before stomach cancer
A promising new biomarker that appears in patients before stomach cancer develops may help with early detection of the disease and improve patient response to therapy, according to findings in a study led by University of Arizona Health Sciences researchers.…
UC studies tobacco use, cancer connection
Research shows that tobacco use changes the metabolism of a type of kidney cancer which could lead to individualized treatment
Enhanced-image endoscopy more effective than conventional imaging for detecting upper GI cancers
Embargoed News from Annals of Internal Medicine
Body MRI reinterpretations plagued by discrepancies and errors
Secondary interpretations of body MR images at tertiary care centers identify high rate of discrepancies, with cognitive error types predominating, suggesting subspecialty interpretations and additional resources are needed
Study identifies gene variants to help personalize treatment of eosinophilic esophagitis
Findings suggest precision medicine could improve treatment for children with eosinophilic esophagitis
All-terrain microrobot flips through a live colon
WEST LAFAYETTE, Ind. — A rectangular robot as tiny as a few human hairs can travel throughout a colon by doing back flips, Purdue University engineers have demonstrated in live animal models. Why the back flips? Because the goal is…
Nearly 1 in 8 patients receive unexpected out-of-network bills after colonoscopy
Embargoed news from Annals of Internal Medicine
Asthma and food allergies during childhood associated with increased risk of IBS
Asthma and food hypersensitivity at age 12 is associated with an increased risk of having irritable bowel syndrome at 16, a new study presented today at UEG Week Virtual 2020 has found.
COVID-related delays to CRC screening causing 11.9% rise in death rates, research reveals
Based on survival rates at 5 years for stage III-IV CRC, the results showed a significant 11.9% increase in deaths when comparing a 0-3 month delay to a >12 month delay
Weight loss surgery in obese diabetic patients significantly cuts pancreatic cancer risk
Weight loss surgery significantly cuts the risk of developing pancreatic cancer in people who are obese with diabetes, a new 20-year analysis has found
Could a poo transplant one day be the secret of eternal youth?
Peer reviewed – experimental study – mice
Biomedical sciences researchers find new way to prevent and cure rotavirus, other viral infections
ATLANTA–A combination of two substances secreted by the immune system can cure and prevent rotavirus infection, as well as potentially treat other viral infections that target epithelial cells, which cover body surfaces such as skin, blood vessels, organs and the…
Caesarean birth, prolonged labour influence infant gut bacteria, risk of childhood obesity
U of A researchers identify specific bacteria linked with changes in gut microbiome of infants
AGA releases largest report on safety and effectiveness of fecal microbiota transplantation
Ninety percent of patients tracked in the AGA FMT National Registry were cured of C. difficile infection with few serious side effects.
Repurposed anti-malarial compounds kill diarrheal parasite, study finds
CHAMPAIGN, Ill. — A class of compounds used for malaria treatment also kill the intestinal parasite Cryptosporidium, a leading cause of diarrheal disease and death in children that has no cure, a multi-institution collaboration of researchers found in a new…
Single-cell RNA sequencing reveals details about individual cells in pancreatic tumors
TGen and HonorHealth investigators suggest this granular analysis could lead to better treatments for pancreatic cancer patients
High-fibre diet, low level inflammation: sidestepping the effects of radiation
Loved or hated, the humble oat could be the new superfood for cancer patients as international research shows a diet rich in fibre could significantly reduce radiation-induced gut inflammation. Conducted by the University of Gothenburg, Lund University and the University…
Study reveals dietary fructose heightens inflammatory bowel disease
STONY BROOK, NY, September 29, 2020 – Diet remains an important part of disease prevention and management, and a new study suggests that consumption of fructose may worsen intestinal inflammation common to inflammatory bowel diseases (IBD). Led by David Montrose,…
Drug found to correct gene defect that causes immune-driven gut leakiness
UC Riverside-led study is the first to show how tofacitinib rescues gut barrier function from overactive immune cells
Genetic Testing Cost Effective for Newly Diagnosed GIST
UC San Diego School of Medicine researchers reported that genetic testing is cost-effective and beneficial for newly diagnosed patients with metastatic gastrointestinal stromal tumors (GIST), a rare type of cancer.
Genetic testing cost effective for newly diagnosed GIST
Because gastrointestinal stromal tumors (GIST) are sensitive to the targeted small molecule therapy imatinib, oncologists tend to treat all patients with metastatic GIST with this drug. However, because this rare type of cancer is caused by different genetic mutations, imatinib…
Team develops wearable sensor to help people with inflammatory bowel disease
Researchers’ device tracks biomarkers in sweat, may indicate flare-ups
Hypercoagulability in patients with coronavirus disease (COVID-19)
Because COVID-19 may present with medium to large arterial and venous abdominal and extremity macrothrombi, radiologists should raise concern for COVID-19 when identifying thromboembolic abdominopelvic findings
Researcher gets $1.95 million grant to study how gut bacteria cause decline of aging immune system
ATLANTA–Dr. Leszek Ignatowicz, a professor in the Institute for Biomedical Sciences at Georgia State University, has received a five-year, $1.95 million federal grant to study how changes in the microorganisms in the gut, referred to as intestinal microbiota, cause the…
Cincinnati Children’s scientists identify hormone that might help treat malabsorption
Human intestinal organoids grown from stem cells used to model congenital disorder in babies
Coffee associated with improved survival in metastatic colorectal cancer patients
BOSTON – In a large group of patients with metastatic colorectal cancer, consumption of a few cups of coffee a day was associated with longer survival and a lower risk of the cancer worsening, researchers at Dana-Farber Cancer Institute and…
Pattern of gut bacteria linked to effectiveness of chemotherapy in breast cancer patients
Researchers studying the activity of gut bacteria in breast cancer patients have found a possible link with how well their chemotherapy works. The study, presented at the 12th European Breast Cancer Conference, included a small group of women who were…
Examining association of coffee consumption, survival in patients with colorectal cancer
What The Study Did: Researchers in this observational study investigated the association between the number of cups of coffee consumed per day and survival in patients with advanced or metastatic colorectal cancer. Authors: Christopher Mackintosh, M.L.A., a medical student at…
Next-gen organoids grow and function like real tissues
Organoids are fast-becoming one of the most cutting-edge tools of modern life sciences. The idea is to use stem cells to build miniature tissues and organs that accurately resemble and behave like their real counterparts. One can immediately appreciate the…
Molecular basis underlying colorectal cancer revealed
A team of scientists has unraveled the molecular mechanism behind one of the causes of colorectal cancer, and a treatment target. The Wnt signaling pathway is a cell signaling pathway that promotes cell proliferation and is essential for the development…
University of South Carolina study reveals how cannabinoids may be useful to prevent colon cancer
COLUMBIA, SC — Inflammatory bowel diseases (IBD) such as Crohn’s disease and ulcerative colitis are caused by unrestrained inflammation of the gastrointestinal tract. Patients with IBD are at a higher risk of developing colorectal cancer. In a recent study published…
High-risk Patients for Colorectal Cancer Lack Knowledge About Colonoscopy
Many clinicians rely on self-reports from their high-risk patients about their need and proper interval for repeat surveillance colonoscopy. Researchers analyzed data over four years to explore the knowledge of these high-risk patients. Twenty-eight percent were unaware of either the need for a repeat colonoscopy or the proper surveillance interval. Of these, 16.6 percent were unaware of the proper three-year interval to obtain a follow-up surveillance colonoscopy. Also, 12 percent were not even aware that they required a follow-up surveillance colonoscopy.
Researchers discover gene that could decrease likelihood of developing alcoholic cirrhosis
INDIANAPOLIS–Researchers at Indiana University School of Medicine are learning more about how a person’s genes play a role in the possibility they’ll suffer from alcoholic cirrhosis with the discovery of a gene that could make the disease less likely. Alcoholic…
Human norovirus strains differ in sensitivity to the body’s first line of defense
Interferon (IFN) responses are one of the first defenses the body mounts against viral infections, and research has shown that it plays a role controlling viral replication. But when researchers at Baylor College of Medicine investigated whether IFN restricted human…
Sampling the gut microbiome with an ingestible pill
Gut microbes affect human health, but there is still much to learn, in part because they’re not easy to collect. But researchers now report in ACS Nano that they have developed an ingestible capsule that in rat studies captured bacteria…
Black people more likely than others to die from colorectal cancer spreading to the liver
Social reform to eliminate health disparities is necessary so that Black people, the most vulnerable group for advanced colorectal cancer, get the care they need for a disease that is curable if caught early, says City of Hope expert
Gut microbes could allow space travelers to stay healthy on long voyages
Review highlights that treatments targeting the gut microbiome could protect space travelers against negative health effects of space travel
Prophylactic antivirals prevent chronic HCV in patients receiving kidneys from positive donors
Embargoed News from Annals of Internal Medicine
AGA recommends bidirectional endoscopy for most patients with iron deficiency anemia
Early gastrointestinal evaluation can lead to the identification and treatment of underlying causes such as gastrointestinal malignancy, peptic ulcer disease and inflammatory bowel disease
Scientists discover key regulator of neuron function and survival
Preclinical study in Cell Reports points to possible treatment for epileptic seizures
How bacteria adhere to fiber in the gut
Molecular mechanics of bacterial superglue
Two discoveries boost next-generation organoid development
New research collaboration tunes into signals that will help make better organoids to mimic functions of the trachea, esophagus, stomach, liver, gallbladder, bile ducts and pancreas
During COVID-19, liver disease and transplant patients need targeted and sustained support
Digital ILC 2020: The liver community has been prompt in addressing the challenges of COVID-19 for liver patients – joining forces to support these patients, provide recommendations to their doctors, and keep research at the forefront.
Liver fibrosis in routine care for diabetes could uncover advanced liver disease patients
Digital ILC 2020: A pilot study from the UK has suggested that diagnosis of advanced liver disease in people living with diabetes could be increased 5-fold if the assessment of liver fibrosis is included in routine care.
Novel agents for the treatment of chronic HBV infection have cure in their sights
Digital ILC 2020: Focused viral hepatitis sessions at Digital International Liver Congress™ 2020 reveal new drugs that aim to cure chronic HBV infection