The present article reviews the emerging role of melatonin (MT) and the Hippo-Yes-associated protein signaling pathway in periodontal regeneration, highlighting their potential to delay the aging process of periodontal ligament stem cells (
Tag: Melatonin
Melatonin-based priming of stem cells to alleviate oxidative stress
Stem cell expansion in vitro and transplantation in the cytokine-rich proinflammatory milieu in the injured tissue generate immense oxidative stress that interferes with the cells’ survival, stemness, and repairability. Stem cell priming
Yes-associated protein-mediated melatonin regulates the function of periodontal ligament stem cells under oxidative stress conditions
BACKGROUNDHuman periodontal ligament stem cells (PDLSCs) regenerate oral tissue. In vitro expansion causes replicative senescence in stem cells. This causes intracellular reactive oxygen species (ROS) accumulation, which can impair stem cel
Mount Sinai Researchers Identify Potential New Treatment for Those Who Act Out Their Dreams While Sleeping
Experts say medication commonly used to treat insomnia may also be a therapeutic option for the condition known as REM sleep behavior disorder
Use of melatonin linked to decreased self-harm in young people
Medical sleep treatment may reduce self-harm in young people with anxiety and depression, an observational study from Karolinska Institutet in Sweden suggests.
Combining Melatonin with Vancomycin Reduces Kidney Failure
A study by researchers at the Rutgers Ernest Mario School of Pharmacy finds that melatonin significantly reduces kidney failure in people being treated with the antibiotic vancomycin.
The Latest Science on Staying Healthy During Pregnancy
Healthy habits are particularly important during pregnancy. Four new studies being presented at NUTRITION 2021 LIVE ONLINE look at how supplements, eating habits and physical activity can affect various aspects of health during pregnancy.
Missing the mark with melatonin: Finding the best treatment for insomnia
Stressful days and sleepless nights leave many people searching for a quick solution to their sleep troubles – is melatonin the answer? As the coronavirus pandemic enters its second year, stress and anxiety are leaving many American adults struggling to…
Seasons of Our Hormones
Weizmann Institute scientists analyzed around six million blood tests to obtain data on several types of hormones, discovering that some peak in winter/spring and others in summer. Peaks in stress or reproductive hormones may have “evolved to help us cope with seasonal changes in our surrounding environment.”
Researchers Develop First Model to Predict Likelihood of Testing Positive for COVID-19 and Outcomes from the Disease
Cleveland Clinic researchers have developed the world’s first risk prediction model for healthcare providers to forecast an individual patient’s likelihood of testing positive for COVID-19 as well as their outcomes from the disease.
According a new study published in CHEST, the risk prediction model (called a nomogram) shows the relevance of age, race, gender, socioeconomic status, vaccination history and current medications in COVID-19 risk.