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UrduImmunotherapy also appears to fuel tumor growth in these cancers
Tag: Internal Medicine
Fatty liver hepatitis is caused by auto-aggressive immune cells
Non-alcoholic steatohepatitis (NASH), often called ‘fatty liver hepatitis’, can lead to serious liver damage and liver cancer. A team of researchers at the Technical University of Munich (TUM) has discovered that this condition is caused by cells that attack healthy…
Aging cells in abdominal fluid cause increased peritoneal dissemination of gastric cancer
Closing in on complete control over peritoneal dissemination of cancer.
study: Precautions used to prevent COVID-19 decreased common respiratory illness rates
Boston – Wearing masks and physical distancing – two key infection prevention strategies implemented to stop the spread of COVID-19 – may have led to the dramatic decrease in rates of common respiratory viral infections, such as influenza. A study…
Large new study reveals rates of brain abnormalities in healthy children
A large study of brain MRI scans from 11,679 nine- and ten-year-old children reviewed by UC San Francisco neuroradiologists identified potentially life-threatening conditions in 1 in 500 children, and more minor but possibly clinically significant brain abnormalities in 1 out…
Common inflammatory bowel disease treatment linked to reduced COVID-19 antibody response
New evidence indicates the commonly-prescribed inflammatory bowel disease (IBD) drug infliximab blunts the immune system to COVID-19 infection, potentially increasing the risk of reinfection.
Ultra-processed foods are breaking your heart
Ultra-processed food consumption associated with increased risk of heart disease, death
Total knee replacement cost effective for patients with osteoarthritis and extreme obesity
Embargoed news from Annals of Internal Medicine
New Barrett’s esophagus monitoring method could aid in easier and more precise prognoses
CLEVELAND–A new technique for sampling and testing cells from Barrett’s esophagus (BE) patients could result in earlier and easier identification of patients whose disease has progressed toward cancer or whose disease is at high risk of progressing toward cancer, according…
Unmet need for equipment to help with bathing, toileting among older adults
What The Study Did: This study estimates how many older adults in the United States who need equipment to help with bathing and toileting don’t have it and the factors associated with not having such equipment. Authors: Kenneth Lam, M.D.,…
Anti-tuberculosis drug can be safely dosed even higher
Publication in European Respiratory Journal
Readmission rate high for adults hospitalized for diabetic ketoacidosis
Readmitted patients with type 1 diabetes have two times the death rate during second hospitalization
Combination thyroid hormone therapies treat hypothyroidism as well as levothyroxine
Treatment should be individualized for common thyroid condition, researchers say
Genetic evidence suggests men can develop PCOS-like condition
Study indicates PCOS may not be primarily a female reproductive disorder
Many endocrine patients, providers want to continue telehealth after pandemic
Three in four patients say telehealth quality of care is similar to in-person visits
Study finds oral testosterone therapy undecanoate is effective, with no liver toxicity
Safety profile consistent with non-oral testosterone replacement products
Semaglutide reduces excess body fat in people with obesity
Findings suggest drug has potential to reduce risk of heart disease, diabetes and stroke
Research reveals human immune system reduces potency of antibiotics
Research from the University of Kent’s School of Biosciences has revealed that a molecule produced by the human immune system can severely diminish the potency of certain antibiotics.
1 in 3 older thyroid patients take medications that interfere with thyroid function tests
Study highlights complexity of managing thyroid hormone replacement in older adults
Osteoporosis drug prescribing often does not follow guidelines
Recommended osteoporosis treatment after hip fracture rarely occurs, study finds
Research reveals human immune system reduces potency of antibiotics
Research from the University of Kent’s School of Biosciences has revealed that a molecule produced by the human immune system can severely diminish the potency of certain antibiotics. This may explain why antibiotics effective in laboratory settings can be less…
Reversing cancer’s gluttony
Researchers report that pancreatic cancer tumors use multiple mechanisms to avoid starvation, suggesting a new target for treating a very difficult and deadly disease
Novel treatment for life-threatening lung condition wins NSF support
WEST LAFAYETTE, Ind. – A Purdue University-affiliated startup developing a novel treatment for a life-threatening lung condition has won a $256,000 Small Business Technology Transfer Phase I award from the National Science Foundation. Spirrow Therapeutics offers help for patients with…
Consumption of added sugar doubles fat production
Sugar is added to many common foodstuffs, and people in Switzerland consume more than 100 grams of it every day. The high calorie content of sugar causes excessive weight and obesity, and the associated diseases. But does too much sugar…
Surgery should remain as mainstay of treatment for acute uncomplicated appendicitis
An RCSI study conducted in Beaumont Hospital in Dublin has found that surgery, rather than antibiotics-only, should remain as the mainstay of treatment for acute uncomplicated appendicitis. Published in the Annals of Surgery and led by researchers from the RCSI…
Switching from TDF- to TAF-containing ART associated with the development of obesity in people living with HIV
Embargoed News from Annals of Internal Medicine
Screening mammography recommendations by breast cancer centers
What The Study Did: Researchers examined the screening mammography recommendations regarding starting age and interval for nearly 500 breast cancer centers in the United States. Authors: Jennifer L. Marti, M.D., of Weill Cornell Medicine in New York, is the corresponding…
Exercise during pregnancy may save kids from health problems as adults
Parental obesity predisposes children to develop diabetes, metabolic issues
CT colonography most effective noninvasive colorectal cancer screening test
Compared with multi-target stool-DNA and fecal immunochemical test, CT colonography with 10 mm threshold most effectively targets advanced neoplasia–preserving detection while decreasing unnecessary colonoscopies
CHOP researchers reveal how critical part of lung forms at cellular level
Knowing which cells are involved in the formation of healthy lung tissue at birth may provide a basis for therapies that help regenerate a critical portion of the lung
Discovery of new protein with an important role in atherosclerosis
Atherosclerosis is the underlying condition that causes heart attacks and strokes. Researchers at Radboudumc in the Netherlands have discovered a protein that appears to play an important role in atherosclerosis. The protein is called Prosaposin, and its role in atherosclerosis…
Multicellular liver-on-a-chip for modeling fatty liver disease
(LOS ANGELES) – Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease worldwide. It is found in 30% of people in developed countries and occurs in approximately 25% of people in the United States. Risk factors for…
Health behavior outcomes can help determine efficacy of interventions for multimorbidities
Scaling up patient-centered interdisciplinary care for multimorbidity: A pragmatic mixed-methods randomized controlled trial
FDA qualifies C-Path’s Diary for Irritable Bowel Syndrome Symptoms-Constipation (DIBSS-C)
TUCSON, Ariz., March 9, 2021 — Critical Path Institute’s (C-Path) Patient-Reported Outcome (PRO) Consortium announces the qualification of the Diary for Irritable Bowel Syndrome Symptoms-Constipation (DIBSS-C) by the U.S. Food and Drug Administration (FDA). The DIBSS-C was developed by the…
Characterizing different cell types in the upper gastrointestinal tract
Researchers from the group of Hans Clevers identified and characterized rare cell types in the upper gastrointestinal tract. Using single cell RNA sequencing, they studied the cellular composition of the esophagus, stomach and upper part of the small intestine. They…
Home testing for COVID-19 could prevent infections and reduce deaths at justifiable cost
New Haven, Conn. — Mailing a package of SARS-CoV-2 tests to every household in America and asking people to use them once a week could greatly reduce total infections and mortality at a justifiable cost, a new study led by…
Food insecurity may make losing weight more difficult, even with an intense intervention
Embargoed news from Annals of Internal Medicine
Canadian scientists and Swiss surgeons discover the cause of excess post-surgical scarring
The finding could improve recovery from abdominal and pelvic surgery
RCSI researchers discover new way to halt excessive inflammation
DUBLIN, Friday, 5 March 2021: RCSI researchers have discovered a new way to ‘put the brakes’ on excessive inflammation by regulating a type of white blood cell that is critical for our immune system. The discovery has the potential to…
The gut mycobiome influences the metabolism of processed foods
New research in mice points to a significant role for fungi to shape metabolism, including fat deposition, and metabolic hormones.
Controlling adhesions in the abdomen
Scars inside the abdomen, known as adhesions, form after inflammation or surgery. They can cause chronic pain and digestive problems, lead to infertility in women, or even have potentially life-threatening consequences such as intestinal obstruction. If adhesions develop, they must…
Do known drugs help against SARS-coronavirus-2?
There are no therapeutics available that have been developed for COVID-19 treatment. Repurposing of already available medication for COVID-19 therapy is an attractive option to shorten the road to treatment development. The drug Camostat could be suitable. Camostat exerts antiviral…
Study links kidney stones with bone problems
In an analysis of nationwide data from the Veterans Health Administration, approximately one-quarter of individuals with kidney stones had a diagnosis of osteoporosis or bone fracture around the time of their kidney stone diagnosis. The findings are published in the…
Diagnosis of genetic condition could help patients stop smoking and prevent lung disease
Estimated 40,000 smokers in Ireland with condition are undiagnosed
Albumin provides no benefit to hospitalized patients with advanced liver disease
Peer reviewed; randomized controlled trial; people
Study reveals frequency and characteristics of stroke in COVID-19 patients
Findings also show coronavirus patients with stroke face increased need for long-term care
New study gives the most detailed look yet at the neuroscience of placebo effects
A large proportion of the benefit that a person gets from taking a real drug or receiving a treatment to alleviate pain is due to an individual’s mindset, not to the drug itself. Understanding the neural mechanisms driving this placebo…
Division of labor within regenerating liver maintains metabolism, mouse study finds
CHAMPAIGN, Ill. — The liver has a rare superpower among body organs – the ability to regenerate, even if 70% of its mass is removed. It also keeps up its metabolic and toxin-removing work during the process of regeneration, thanks…
CER-001 helps restore kidney function and vision for patient with rare genetic kidney disease
Embargoed news from Annals of Internal Medicine
Multiple aspects of Coronavirus disease
The Coronavirus Disease 2019 (COVID-19) pandemic has affected almost every part of the globe with millions of cases and over a million deaths. The pandemic has had a significant global economic impact and addressing it systematically requires significant efforts from…