Bacteria could be used to produce large quantities of medicines and fuels using a new gene programming technique, research suggests. The powerful method could enable bacteria to be used as cheap and environmentally friendly living factories that make a range…
Tag: genes
Scientists have found longevity biomarkers
An international group of scientists studied the effects of 17 different lifespan-extending interventions on gene activity in mice and discovered genetic biomarkers of longevity. The results of their study were published in the journal Cell Metabolism . Nowadays, dozens of…
A novel technology for genome-editing a broad range of mutations in live organisms
Salk scientists develop a new gene-editing tool that could help treat many disorders caused by gene
Bacterial sex drives evolution of microbes to conquer and colonize the gut
pioneer study now published in Proceedings of the National Academy of Science – USA, the research te
Moderate to Heavy Drinking During Pregnancy Alters Genes in Newborns, Mothers
Mothers who drink moderate to high levels of alcohol during pregnancy may be changing their babies’ DNA, according to a Rutgers-led study.
Dartmouth receives $12.5 million grant to establish Center for Quantitative Biology
Dartmouth’s Geisel School of Medicine has been awarded a 5-year, $12.5 million grant from the National Institutes of Health (NIH) to establish a Center for Quantitative Biology (CQB) that will bring together and enhance initiatives in computational biology, bioinformatics, and…
Tweaked CRISPR in neurons gives scientists new power to probe brain diseases
A team of scientists at UC San Francisco and the National Institutes of Health have achieved another CRISPR first, one which may fundamentally alter the way scientists study brain diseases. In a paper published August 15 in the journal Neuron…
Genetic redundancy aids competition among bacteria in symbiosis with squid
The molecular mechanism used by many bacteria to kill neighboring cells has redundancy built into its genetic makeup, which could allow for the mechanism to be expressed in different environments. Some strains of luminescent bacteria that compete to colonize the…
AAV9 gene therapy vector dramatically increases life span in krabbe disease mouse model
New Rochelle, NY, August 12, 2019–An optimized and newly engineered form of the adeno-associated vector 9 (AAV9) vector used to deliver the galactosylceramidase gene to a mouse model of the inherited neurogenerative and rapidly fatal form of Krabbe dis-ease improved…
Simple protocol for assessing maturation of HPCs from induced pluripotent stem cells
New Rochelle, NY, August 13, 2019-Researchers have developed a guide to help labs standardize the production of mature hepatic-like cells (HPCs) from stem cells and easily compare gene expression of HPCs to actual human liver tissue. This moderately high throughput…
NIH’s All of Us Research Program recaps progress and next steps
WHAT: The All of Us Research Program at the National Institutes of Health has made strong progress in its efforts to advance precision medicine, according to program leadership in a forthcoming paper in the New England Journal of Medicine .…
Helping bacteria be better friends
Engineering multiple bacterial strains reverses antagonistic interactions and results in more balanc
Genes linked to Alzheimer’s risk, resilience ID’d
Genes in the brain’s immune cells may point to strategy to protect against the disease
Gene mutation combo linked to common cancer in women
Michigan State University researchers, in collaboration with the Van Andel Institute, have identified a combination of two gene mutations that is linked to endometrial cancer.
A Snapshot in Time: Study Captures Fleeting Cell Differences That Can Alter Disease Risk
In cinema and science fiction, one small change in the past can have major, sometimes life-changing effects in the future. Using a series of snapshots, researchers recently captured such so-called “butterfly effects” in heart muscle cell development, and say this…