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UrduWhat The Study Did: Researchers looked at demographic, socioeconomic and clinical factors that were associated with timely access to hearing aids for children. To access the embargoed study: Visit our For The Media website at this link https:/ / media.…
Tag: Clinical Trials
AI and big data predict which research will influence future medical treatments
An artificial intelligence/machine learning model to predict which scientific advances are likely to eventually translate to the clinic has been developed by Ian Hutchins and colleagues in the Office of Portfolio Analysis (OPA), a team led by George Santangelo at…
Taking RTKI drugs during radiotherapy may not aid survival, worsens side effects
UNIVERSITY PARK, Pa. — Taking certain cancer-fighting drugs while undergoing radiation therapy may not increase survival for patients, but may, instead, increase side effects, according to a team of researchers. The drugs, however, may be beneficial for patients who are…
Skin cancer above the neck more likely to spread, research shows
(MADRID, 11 October, 2019) New results from a descriptive, 6-month clinical study suggest that malignant melanoma (MM) that develops on the neck has a higher chance of spreading beyond the skin compared with MM that develops below the neck. However,…
Virtual review of cancer clinical trial treatment options quicker than conventional method
WASHINGTON — Using virtual, cloud-based, interconnected computing techniques applied to 51,000 variables, researchers at Georgetown University Medical Center and colleagues reduced the time needed to assess a cancer patient’s tumor profile and suitability for clinical trials from 14 to 4…
NCI-sponsored trial explores better treatment for brain tumors in children
AUGUSTA, Ga. (Oct. 8, 2019) Children with recurrent brain tumors or newly diagnosed, particularly aggressive tumors called diffuse intrinsic pontine gliomas are being enrolled in the first study to examine the efficacy of a drug that inhibits an enzyme these…
Prenatal stress could affect baby’s brain, say researchers
New research from King’s College London has found that maternal stress before and during pregnancy could affect a baby’s brain development. In their study published in Biological Psychiatry , MRC Doctoral Researcher in Perinatal Imaging and Health, Alexandra Lautarescu and…
Nanostics expands ClarityDX prostate clinical study into the United States
Nanostics is expanding its ClarityDX Prostate clinical validation study into the US by opening the Florida-based Century Clinical Research Inc. recruitment site; significantly accelerating the study timeline and increasing patient cohort diversity.
Rice bran may help curb malnutrition, diarrhea for infants
Results from a clinical trial in Nicaragua and Mali
Clinical research for PET imaging for prostate cancer begins at Osaka University Hospital
Osaka University Hospital began Japan’s first clinical research for diagnosis of prostate cancer (PC) using PET (positron emission tomography) scan results in September 2019. In this study, the 18 F-labelled PSMA-1007 radiotracer (fluorine-18 [ 18 F]-PSMA-1007) that targets Prostate Specific…
Cincinnati Children’s receives NIH grant renewal on eosinophilic disorders
CINCINNATI — Cincinnati Children’s Hospital Medical Center has received a 5-year, $7.57 million grant renewal from the National Institutes of Health (NIH) to continue leading a consortium of organizations from around the country that will conduct clinical research into eosinophilic…
Secrets of lung cancer spread found in patients’ blood and biopsies
Early signs that a patient’s lung cancer may spread and become untreatable can be picked up in samples of their blood and tumour, according to a trio of papers published in Nature Medicine today (Monday). The three studies are all…
North American IASLC North America Conference on Lung Cancer- – Oct. 10-12
What: The International Association for the Study of Lung Cancer (IASLC) will host the North America Conference on Lung Cancer Oct. 10-12, 2019, in Chicago, Illinois. The IASLC North America conference is an educational and scientific event covering key aspects…
Kessler scientists receive grant to study exercise benefits in multiple sclerosis
Consortium of Multiple Sclerosis Centers awards grant to Drs. John DeLuca and Helen Genova to study the effects of different exercise regimens across multiple realms of symptoms and functioning
Long-term study data shows DBS is effective treatment for most severe form of depression
A study published online on Friday, October 4, in the American Journal of Psychiatry found that deep brain stimulation (DBS) of an area in the brain called the subcallosal cingulate (SCC) provides a robust antidepressant effect that is sustained over…
High fiber diet associated with reduced CV risk in hypertension, type 2 diabetes patients
Medical nutrition therapy paired with medical treatment may reduce future heart disease
$28m grant funds coordinating center for Rare Diseases Clinical Research Network
The federal agency that oversees a large network of research centers seeking cures for hundreds of rare, disabling and often fatal diseases has named Cincinnati Children’s as its new data management and coordinating center. The five-year, $28 million grant from…
Response rate to albumin-bound paclitaxel plus gemcitabine plus cisplatin treatment among patients with advanced pancreatic cancer: A phase 1b/2 pilot clinical trial
Clinical trial demonstrates substantial patient benefit in treating late-stage pancreatic cancer one of the most aggressive of all cancers
FODMAPs diet relieves symptoms of inflammatory bowel disease
New research from King’s College London has found that a diet low in fermented carbohydrates has improved certain gut symptoms and improved health-related quality of life for sufferers of inflammatory bowel disease (IBD).
Sex-based differences in the development of brain hubs involved in memory and emotion
Findings may help researchers understand why mental disorders present differently in males and females during adolescence
Fourth baby born after uterus transplant at Baylor University Medical Center in Dallas
Family of fourth baby shares their story of hope
CSHL press publishes ‘Conscience and Courage,’ the remarkable life story of Henri Termeer
Cold Spring Harbor, New York, October 1, 2019 — Cold Spring Harbor Laboratory Press (CSHL Press) today announced the publication of Conscience and Courage: How Visionary CEO Henri Termeer Built a Biotech Giant and Pioneered the Rare Disease Industry. Written…
Treatment with long term, low dose antibiotic could help people born with chronic lung condition
Madrid, Spain: Taking a low dose of the antibiotic azithromycin for six months reduces symptoms for patients with the chronic lung condition primary ciliary dyskinesia (PCD), according to research presented at the European Respiratory Society International Congress. [1] PCD is…
Study demonstrates antibody responses within 6 weeks of initial vaccination
SEATTLE, OCTOBER 01, 2019 – An early phase study was conducted in the U.S. in which different combinations of DNA (DNA-HIV-PT123) and protein (AIDSVAX® B/E) vaccines were administered in four randomized treatment groups (T1, T2, T3, T4), to determine which…
Cerebral reperfusion of reading network predicts recovery of reading ability after stroke
New Jersey researchers find early reperfusion of left reading network predicts reading ability in people recovering from left-sided stroke
New in Ethics & Human Research, September-October 2019
Participant Engagement in Translational Genomics Research: Respect for Persons–and Then Some Janet E. Childerhouse, Candice R. Finnila, Joon-Ho Yu, Barbara A. Koenig, Jean McEwen, Stacey L. Berg, Benjamin S. Wilfond, Paul S. Appelbaum, and Kyle B. Brothers The expansion of…
New study links vitamin C therapy to better survival rates after sepsis
Exploratory 3-year study finds that treating septic patients with intravenous vitamin C could lead to decreased mortality, quicker recovery
The Lancet journals: Papers at ERS Congress 2019
The following papers will be presented at the ERS Congress 2019, organised by the European Respiratory Society, in Madrid and published simultaneously in either The Lancet or The Lancet Respiratory Medicine journals. All papers are under embargo until the stated…
New clinical trial analyses predict response to benralizumab by patients with COPD
Analyses of two international clinical trials predict response to asthma drug benralizumab by subpopulation of patients with COPD
New smallpox vaccine tested by USAMRIID receives FDA approval
Army scientists played a key role in testing a new smallpox vaccine approved last week by the U.S. Food and Drug Administration. Marketed under the brand name JYNNEOS, the product, developed by Bavarian Nordic, is a live, non-replicating vaccine for…
University of Cincinnati experts research going keto to fight cancer
Scientists are studying whether an Atkins-type ketogenic diet could help make treatments for glioblastoma more effective
Blood test can replace invasive biopsy for more patients with lung cancer
ESMO 2019 Congress, Sept. 27 — Oct. 1, Barcelona, Spain
Mesothelioma trial suggests immunotherapy as an alternative to chemotherapy
ESMO 2019 Congress, Sept. 27 — Oct. 1, Barcelona, Spain
TAILORx: New data on cohort with recurrence score 26-100 shows 93% cancer-free rate at 5 years
The prospective TAILORx trial has 5 year clinical outcomes with chemo and high Recurrence Score 26-100, in JAMA Oncology and at ESMO today. 4th peer-reviewed publication for TAILORx, which continues to define new standards in early breast cancer.
First targeted therapy for cholangiocarcinoma shows clinical benefit in phase III trial
ESMO 2019 Congress, Sept. 27 — Oct. 1, Barcelona, Spain
Targeted therapy slows progression of advanced prostate cancer
ESMO 2019 Congress, Sept. 27 — Oct. 1, Barcelona, Spain
GARDP and Entasis Therapeutics initiate global phase 3 trial of zoliflodacin
The Global Antibiotic Research and Development Partnership (GARDP), a not for profit organisation developing new treatments for drug resistant infections, and Entasis Therapeutics (NASDAQ: ETTX), a clinical-stage biopharmaceutical company focused on the discovery and development of novel antibacterial products, today…
ESMO 2019: Breast and ovarian cancer drug outperforms targeted hormone therapy in some men
A drug used for breast and ovarian cancer is more effective than modern targeted hormone treatments at slowing progression and improving survival in some men with advanced prostate cancer, phase III clinical trial findings reveal. The PROfound trial compared the…
The Lancet: 3-in-1 inhaler therapy can improve lung function and reduce asthma attacks
Patients with severe asthma which is not controlled with standard treatment – leaving them at risk of severe asthma attacks – could benefit from using a single inhaler combining three, instead of two therapies, according to two phase 3 randomised…
Immune therapy eliminates tumour cells in early triple negative breast cancer
ESMO 2019 Congress, Sept. 27 – Oct. 1, 2019, Barcelona, Spain
Two studies show CDK4/6 inhibitors improve overall survival in advanced breast cancer
ESMO 2019 Congress, Sept. 27 – Oct. 1, 2019, Barcelona, Spain
Wrist-worn step trackers accurate in predicting patient health outcomes
Determining how far patients with pulmonary disease can walk in six minutes has long been an effective clinical tool to help physicians determine their exercise capacity, as well as to aid in predicting health outcomes and mortality. Now, in a…
Targeted therapy drug helps women with aggressive breast cancer live longer
UCLA researchers find ribociclib significantly improves overall survival
Nintedanib slows progression for broad range of scarring lung diseases
Findings suggest all progressive, scarring lung diseases may share similar mechanisms
Ovarian cancer: more women benefit from maintenance combined targeted therapy
ESMO 2019 Congress, Sept. 27 – Oct. 1, 2019, Barcelona, Spain
Two immunotherapy drug combination offers chemotherapy-free option for advanced NSCLC
ESMO 2019 Congress, Sept. 27 — Oct. 1, Barcelona, Spain
Additional heart artery stenting reduces risk of future heart attacks
Research shows that patients requiring emergency heart attack treatment also benefit from further intervention to reduce risk of future heart attacks The international trial included 4000 patients, 713 of which were from the UK in investigations led by the University…
One in two pts with metastatic melanoma alive after 5 years with combination immunotherapy
ESMO 2019 Congress, Sept. 27 – Oct. 1, Barcelona, Spain
Combination immunotherapy drugs herald new hope for melanoma patients with long term survival rates
Royal Marsden Hospital research being presented at ESMO
Front-line osimertinib improves overall survival in EGFR-mutation positive NSCLC
ESMO 2019 Congress, Sept. 27, 2019 – Oct. 1, 2019, Barcelona, Spain